Major interaction on record — check this product against your medications before combining. Based on 5 of 9 ingredients. Check your meds →
Dietary supplement

Total Man Ingredients & Drug Interactions

by Totally Products

Total Man label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Total Man against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Total Man is a dietary supplement by Totally Products with 9 active ingredients. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.Based on those ingredients, 533 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Tongkat Ali, Powder, Mucuna pruriens Seed Extract, Saw Palmetto berry powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Total Man by Totally Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Total Man by Totally Products — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Total Man by Totally Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 9 of its 9 active ingredients.
  • “Horny Goat Weed, Powder” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.

Total Man contains 9 active ingredients. The main ones are saw palmetto berry powder, which has traditionally been used for prostate and urinary concerns; mucuna pruriens seed extract, which contains levodopa, a compound similar to certain Parkinson's medications; and tongkat ali powder, marketed for sexual function and athletic performance.

You'll also find maca powder, panax ginseng powder, arginine, icariin, polypodium vulgare powder, and horny goat weed powder (a blend ingredient listed by component). The capsules also contain inactive ingredients—rice flour, gelatin, and magnesium stearate—that help hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Transurethral resection of the prostate (TURP) — rated "Possibly Effective" (Saw Palmetto) (Natural Medicines).
  • On file: Sexual desire — rated "Possibly Effective" (Eurycoma Longifolia) (Natural Medicines).

The evidence for most ingredients in this product is thin. Saw palmetto shows possibly ineffective evidence for benign prostatic hyperplasia (enlarged prostate), though it is possibly effective for transurethral resection of the prostate (TURP).

Tongkat ali has possibly effective evidence for sexual desire but possibly ineffective evidence for athletic performance. Maca, mucuna pruriens, and muira puama all carry insufficient evidence ratings for their intended uses—meaning the science isn't established enough for us to rate them.

We hold no effectiveness data for panax ginseng, arginine, icariin, polypodium vulgare, or horny goat weed.

The evidence, ingredient by ingredient Maca Saw Palmetto Cowhage Eurycoma Longifolia Muira Puama

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Saw palmetto is generally well tolerated as a food, but long-term safety in supplement amounts hasn't been well studied. Mild side effects like headache, dizziness, nausea, and constipation are uncommon but possible; rarely, cardiac issues like arrhythmia have been reported.

Avoid it during pregnancy and breastfeeding. Mucuna pruriens contains levodopa and should be used carefully with professional guidance.

Common side effects include diarrhea, flatulence, nausea, and abdominal distention. A small number of trial participants taking high doses reported insomnia.

Avoid during pregnancy and breastfeeding. Tongkat ali is generally tolerated short-term in studies, but long-term safety is uncertain; avoid during pregnancy and breastfeeding.

Maca is generally well tolerated as a food, but long-term supplement safety is unstudied; avoid during pregnancy and breastfeeding, and raw maca may cause stomach pain. We hold no safety data on file for muira puama, arginine, icariin, polypodium vulgare, panax ginseng, and horny goat weed.

Side effects, ingredient by ingredient Maca Saw Palmetto Cowhage Eurycoma Longifolia Muira Puama

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Saw Palmetto, Cowhage, Eurycoma Longifolia.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; Parkinson's medications.
  • For scale: 533 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Total Man, check your exact medications against these drug types: blood pressure medications (methyldopa, guanethidine, propranolol), blood thinners (anticoagulants or antiplatelet drugs), MAOIs, levodopa, tricyclic antidepressants, diabetes medications, antipsychotics, estrogens, and hormonal contraceptives. If you take any of these, do not start this product without talking to your doctor or pharmacist first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Total Man is positioned as a men's vitality blend, but most of its ingredients lack strong evidence for the purposes they're marketed for, and several—especially mucuna pruriens and saw palmetto—carry meaningful medication interactions. If you take any blood pressure drugs, antidepressants, diabetes medications, blood thinners, or MAOIs, this product is not safe to start without clearing it first with your doctor or pharmacist.

Even if you don't take medications, talk it over with your healthcare provider to see if this is the right fit for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Total Man, straight from the product label.

Brand Totally Products
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 18, 2023
DSLD ID 294248
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Women (not pregnant or lactating), Adult Male (18-50 Years), Seniors/Mature (>50 Years) - Men ONLY
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Total Man by Totally Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Panax ginseng, Powder20 mg--
Maca powder250 mg--
Arginine20 mg--
Saw Palmetto berry powder100 mg--
Icariin10 mg--
Polypodium vulgare powder20 mg--
Mucuna pruriens Seed Extract30 mg--
Tongkat Ali, Powder100 mg--
Muira Puama, Powder20 mg--
Horny Goat Weed, Powder1000 mg--

Other ingredients: Rice Flour, Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

How to use 2 capsules daily preferably with food 1 to 2 hours prior to physical activity or as directed by a healthcare professional.

Precautions

Caution This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, fish and crustacean shellfish.

Do not exceed recommended dose.

This product is not intended for pregnant or nursing mothers, children under the age of 18, or individuals taking prescription drugs.

This product is not intended for pregnant or nursing mothers, children under the age of 18, or individuals taking prescription drugs.

Discontinue use immediately if nausea, sleeplessness, or nervousness occur.

Do not take this product if you have a known medical condition including high blood pressure, diabetes, any cardiovascular disorder, heart disease, hyperthyroidism, or are taking antidepressant medications.

If you have questions about the advisability of taking this product, consult your physician prior to use.

Warning: Allergen warning: Contains soy (Lecithin)

Keep out of the reach of children.

Do not use if outer seal is broken or damaged.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Formulated in the USA

GMP Good Manufacturing Practices Consistent Quality GMP Certified Facility

General Statements

Please recycle.

Formulation

Performance Strength Stamina Sex drive support formula Prostate & sexual health Circulation Power Energy Drive Give your testosterone a

Formula

Powerful antioxidants

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Total Man by Totally Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Total Man label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Total Man by Totally Products

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Panax ginseng, Powder

20 mg per serving

Maca powder

No known
interactions
250 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca powder monograph & interactions

Arginine

20 mg per serving Form: L-Arginine Hydrochloride

Saw Palmetto berry powder

Interacts with
174 drugs
100 mg per serving

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

Saw Palmetto berry powder monograph & interactions

Polypodium vulgare powder

20 mg per serving

Mucuna pruriens Seed Extract

Interacts with
193 drugs
30 mg per serving

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied...

Mucuna pruriens Seed Extract monograph & interactions

Tongkat Ali, Powder

Interacts with
248 drugs
100 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Tongkat Ali, Powder monograph & interactions

Muira Puama, Powder

No known
interactions
20 mg per serving

Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limite...

Muira Puama, Powder monograph & interactions

Horny Goat Weed, Powder

1000 mg per serving
  • › Icariin

Other (inactive) ingredients: Rice Flour, Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Total Man by Totally Products Drug Interactions

Want to check YOUR meds against Total Man?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
533Drugs
17 Major 353 Moderate 163 Minor

Ingredients driving the most interactions

Tongkat Ali, Powder 248
Mucuna pruriens Seed Extract 193
Saw Palmetto berry powder 174

Individual Drug Interactions

The ingredients in Total Man interact with 533 drugs. Click any drug to see the details.

3 of the 9 ingredients in Total Man interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali, Powder Mucuna pruriens Seed Extract Saw Palmetto berry powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Total Man with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Tongkat Ali, Powder5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Tongkat Ali, Powder full monograph & interactions

Mucuna pruriens Seed Extract8 drug types · 193 drugs

Levodopa

Concomitant use can increase the risk of levodopa-related adverse effects.
Cowhage contains levodopa. Some cowhage products have been standardized to contain 75-400 mg of levodopa per dose.

Likelihood Likely Evidence D
Methyldopa (Aldomet)

Theoretically, concomitant use of cowhage and methyldopa might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with methyldopa might cause additive hypotension. In addition, methyldopa may inhibit peripheral decarboxylation of levodopa and increase levodopa levels in the central nervous system; avoid using.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use of cowhage and non-selective MAOIs might increase the risk of hypertensive crisis.
Cowhage contains levodopa. Use of levodopa with non-selective MAOIs might cause hypertensive crisis. However, this interaction has not been reported with MAO-B selective inhibitors such as selegiline.

Likelihood Probable Evidence D
Anesthesia

Theoretically, concomitant use of cowhage and anesthesia might increase the risk of arrhythmias.
Cowhage contains levodopa. Use of levodopa with cyclopropane or halogenated hydrocarbon anesthesia has led to arrhythmias. Other anesthetics have not been implicated. Use other anesthetics in patients taking cowhage or tell patients to stop taking cowhage at least 2 weeks before surgery.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of cowhage and antidiabetes drugs might increase the risk of hypoglycemia.
Animal research shows that cowhage might have hypoglycemic effects.

Likelihood Possible Evidence D
Antipsychotic Drugs

Theoretically, use of cowhage might decrease the clinical effects of antipsychotic drugs.
Cowhage contains levodopa. Use of levodopa might counteract the antidopaminergic effects of antipsychotic medications.

Likelihood Possible Evidence D
Guanethidine (Ismelin)

Theoretically, concomitant use of cowhage and guanethidine might increase the risk of hypotension.
Cowhage contains levodopa. Use of levodopa with guanethidine might cause additive hypotension; avoid using.

Likelihood Probable Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, use of TCAs might reduce the levels and clinical effects of cowhage.
Cowhage contains levodopa. Use of TCAs might reduce the absorption of levodopa. Some case reports describe patients that developed hypertension and dyskinesia when taking both levodopa and TCAs.

Likelihood Possible Evidence D
Mucuna pruriens Seed Extract full monograph & interactions

Saw Palmetto berry powder3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
Saw Palmetto berry powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Total Man, from the product label.

Totally Products

See all Totally Products products
Name
Totally Products LLC
Street Address
1835 E Hallandale Bch Blvd suite 425
City
Hallandale
State
FL
ZipCode
33009
Phone Number
800-924-0710
Pharmacist Counseling Corner

Total Man by Totally Products: Common Questions

Does Total Man by Totally Products interact with any medications?
Yes. Based on its ingredients, Total Man has a known interaction with 533 medications, including 17 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Total Man contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product actually work for sexual function or athletic performance?
The evidence isn't strong. Tongkat ali has some possibly effective evidence for sexual desire, but the other ingredients—maca, mucuna pruriens, muira puama, horny goat weed—have insufficient evidence or no data we can verify. Talk with your doctor about whether this is worth trying for your specific needs.
Can I take this while pregnant or breastfeeding?
No. Saw palmetto, mucuna pruriens, tongkat ali, maca, and muira puama all have insufficient or unsafe safety data for pregnancy and breastfeeding. Mucuna pruriens in particular contains levodopa, which can lower milk supply. Avoid this product if you're pregnant or nursing, and talk with your doctor before taking it if you're planning pregnancy.
What are the main side effects I might experience?
From saw palmetto: headache, dizziness, nausea, constipation, and rarely cardiac issues. From mucuna pruriens: diarrhea, flatulence, nausea, abdominal bloating, and insomnia in a small number of people. Most people tolerate these ingredients mildly, but effects vary.
Why does this product interact with so many medications?
Mucuna pruriens contains levodopa, which is an active drug-like compound that affects blood pressure, mood, and dopamine in your brain—so it interacts with blood pressure drugs, antidepressants, and psychiatric medications. Saw palmetto has antiestrogenic effects, so it interferes with hormonal drugs. These aren't flaws—they're the compounds actually doing something in your body—but they mean you must be careful about what else you take.
Is this product safe to use with my blood pressure medication?
That depends entirely on which blood pressure drug you take. Mucuna pruriens in this product can dangerously lower blood pressure with methyldopa and guanethidine, and tongkat ali can reduce effectiveness of propranolol. Check the medication list on this page or talk with your pharmacist about your specific medication before starting.
What is mucuna pruriens, and why is it in here?
Mucuna pruriens is a tropical plant seed that contains levodopa, a compound used in Parkinson's disease treatment. It's marketed here as a potential boost to sexual function and mood, but it's a potent ingredient that acts like a medication and carries serious interaction risks. It's not simply a food—it's an active botanical drug.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Total Man is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Total Man label
Go deeper

The Full Monographs Behind Total Man’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Cowhage

Interacts with 193 drugs

Cowhage (Mucuna pruriens) is a tropical legume best known as a natural source of L-dopa, the compound the body turns into dopamine. It is most studied for Parkinson's disease symptoms and ma...

Read the full Cowhage monograph → Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph → Herb & supplement monograph

Muira Puama

Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven,...

Read the full Muira Puama monograph →
Sources

Sources & How We Checked

Total Man's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 41 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Saw Palmetto 22 references
  1. Wilt TJ, Ishani A, Stark G, et al. Saw palmetto extracts for treatment of benign prostatic hyperplasia: a systematic review. JAMA 1998;280:1604-9. PubMed
  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
  3. Di Silverio F, D'Eramo G, Lubrano C, et al. Evidence that Serenoa repens extract displays an antiestrogenic activity in prostatic tissue of benign prostatic hypertrophy patients. Eur Urol 1992;21:309-14. PubMed
  4. Stepanov VN, Siniakova LA, Sarrazin B, Raynaud JP. Efficacy and tolerability of the lipidosterolic extract of Serenoa repens (Permixon) in benign prostatic hyperplasia: a double-blind comparison of two dosage regimens. Adv Ther 1999;16:231-41.
  5. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. PubMed
  6. Jibrin I, Erinle A, Saidi A, Aliyu ZY. Saw palmetto-induced pancreatitis. South Med J 2006;99:611-2. PubMed
  7. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  8. Avins AL, Bent S, Staccone S, et al. A detailed safety assessment of a saw palmetto extract. Complement Ther Med 2008;16:147-54. PubMed
  9. Morgia, G., Mucciardi, G., Gali, A., Madonia, M., Marchese, F., Di, Benedetto A., Romano, G., Bonvissuto, G., Castelli, T., Macchione, L., and Magno, C. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus
  10. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50.
  11. Agbabiaka, T. B., Pittler, M. H., Wider, B., and Ernst, E. Serenoa repens (saw palmetto): a systematic review of adverse events. Drug Saf 2009;32(8):637-647. PubMed
  12. Wargo, K. A., Allman, E., and Ibrahim, F. A possible case of saw palmetto-induced pancreatitis. South.Med.J. 2010;103(7):683-685. PubMed
  13. Lapi, F., Gallo, E., Giocaliere, E., Vietri, M., Baronti, R., Pieraccini, G., Tafi, A., Menniti-Ippolito, F., Mugelli, A., Firenzuoli, F., and Vannacci, A. Acute liver damage due to Serenoa repens: a case report. Br.J.Clin.Pharmacol. 2010;69(5):558-560.
  14. Mantovani, F. Serenoa repens in benign prostatic hypertrophy: analysis of 2 Italian studies. Minerva Urol.Nefrol. 2010;62(4):335-340.
  15. Hanaka, M., Yoshii, C., Yatera, K., Ito, C., Chojin, Y., Nagata, S., Yamasaki, K., Nishida, C., Kawanami, T., Kawanami, Y., Ishimoto, H., and Mukae, H. [A case of rhabdomyolysis caused by saw palmetto of healthy foods]. J.UOEH. 6-1-2012;34(2):193-199. PubMed
  16. Miroddi, M., Carni, A., Mannucci, C., Moleti, M., Navarra, M., and Calapai, G. Hot flashes in a young girl: a wake-up call concerning Serenoa repens use in children. Pediatrics 2012;130(5):e1374-e1376.
  17. Braeckman J. The extract of Serenoa repens in the treatment of benign prostatic hyperplasia: a multicenter open study. Current Therapeutic Research 1994;55(7):776-785. DOI
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  19. Morabito P, Miroddi M, Giovinazzo S, Spina E, Calapai G. Serenoa repens as an endocrine disruptor in a 10-year-Old young girl: a new case report. Pharmacology. 2015;96(1-2):41-3. doi: 10.1159/000431327.
  20. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247.
  21. Paulis G, Paulis A, Perletti G. Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials. Arch Ital Urol Androl 2021;93(4):475-480. PubMed
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Cowhage 12 references
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Eurycoma Longifolia 4 references
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Muira Puama 2 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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