Trans-Resveratrol 100 Milligrams Ingredients & Drug Interactions
by NutraBio
What is this page for?
First and foremost: checking Trans-Resveratrol 100 Milligrams against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Trans-Resveratrol 100 Milligrams is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 826 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Trans-Resveratrol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Trans-Resveratrol 100 Milligrams by NutraBio
Ask about any prescription or over-the-counter medication and we check it for interactions with Trans-Resveratrol 100 Milligrams by NutraBio — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Trans-Resveratrol 100 Milligrams by NutraBio
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: polygonum cuspidatum extract, a plant source of trans-resveratrol. The extract comes in a vegetable capsule, which is the only inactive ingredient listed.
Does it work?
No specific claim
The evidence on hu zhang and resveratrol effectiveness is not established in our data. We hold insufficient reliable evidence for this product's use in hepatitis, rheumatoid arthritis, wound healing, gout, osteoarthritis, and unstable angina.
If you're considering it for one of these conditions, talk with your doctor about whether the evidence supports it and what other options exist.
How safe is it?
Some data gaps
Human safety data for hu zhang are limited. The ingredient's emodin content may cause digestive upset.
The safety data advise against use during pregnancy and breastfeeding — there isn't enough information to know whether it's safe, and some compounds in hu zhang may affect the uterus or bowel. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (moderate risk of increased bleeding), any medications processed by the liver's CYP1A2, CYP2C19, CYP2E1, or CYP3A4 enzymes (moderate risk of raised drug levels), estrogen replacement therapy (moderate risk of reduced effectiveness), or carbamazepine (minor risk of increased effects and side effects). Altogether, these interactions span 827 individual medications.
The bottom line
Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.
This product may be of interest to someone looking for trans-resveratrol support, but it carries moderate interaction risks with blood thinners, antiplatelet drugs, and many medications processed by the liver. If you take any prescription medications — especially blood thinners, seizure drugs, or hormone replacement therapy — check with your doctor or pharmacist before starting.
The same goes if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Trans-Resveratrol 100 Milligrams, straight from the product label.
| Brand | NutraBio |
|---|---|
| Barcode (UPC) | 649908244507 |
| Net contents | 150 V-Cap(s) |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2015 |
| DSLD ID | 51150 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Trans-Resveratrol 100 Milligrams by NutraBio, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Trans-Resveratrol | 100 mg | -- |
| Polygonum cuspidatum extract | 200 mg | -- |
Other ingredients: Vegetable Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
VEGETARIAN
~ ALLERGEN FREE ~ NON-GMO ~ GLUTEN FREE ~ BSE/TSE FREE ~ NON-IRR/ETO
No fillers ~ No Excipients ~ No additives
Free of Harmful Impurities
Formula
ALLERGEN FREE
Suggested/Recommended/Usage/Directions
1 capsule 1-2x daily Suggested Use: As a dietary supplement, take 1 capsule with your favorite beverage, 1-2 times daily, or as directed by a physician.
Precautions
Warning: NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF THE REACH OF CHILDREN.
If you are pregnant or breast feeding, consult your health care practitioner before using this product. People with known medical conditions and/or taking drugs should consult with a licensed physician prior to taking.
General Statements
Manufactured in a GMP & FDA inspected facility
ANTIOXIDANT
ANTIOXIDANT & CARDIOVASCULAR SUPPORT
Pharmaceutical Grade HPLC Lab Tested for Potency
150 Servings 100 Milligrams
Made in a GMP & FDA inspected facility
Since 1996
Made in USA
Vegetable capsule
Seals/Symbols
TRUE LABEL FULL LABEL DISCLOSURE
OU
Storage
STORE IN A COOL DRY PLACE.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
General
24450-005 B20053-002
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Trans-Resveratrol 100 Milligrams by NutraBio label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Trans-Resveratrol 100 Milligrams by NutraBio
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetable Capsule(s) Dosage formCapsule Servings per container150 Amounts shown are per serving.
Trans-Resveratrol
Interacts with822 drugs
Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...
Trans-Resveratrol monograph & interactionsOther (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.
Trans-Resveratrol 100 Milligrams by NutraBio Drug Interactions
HelloPharmacist Interaction Report
Trans-Resveratrol 100 Milligrams by NutraBio contains polygonum cuspidatum extract (hu zhang), which has documented interactions with several medication types.
The most serious concern is a moderate-severity interaction with blood thinners and antiplatelet drugs (such as warfarin and aspirin), where the ingredient may increase bleeding risk through its antiplatelet effects.
Read the full breakdown — every affected drug type, severity by severity
The product may also affect how your body metabolizes a large number of medications. Hu zhang contains resveratrol, which appears to inhibit several liver enzymes (CYP1A2, CYP2C19, CYP2E1, and CYP3A4) in laboratory studies.
This could theoretically raise blood levels of drugs processed by these pathways — though a human study of high-dose resveratrol did not require dose adjustments to other medications. Additionally, the product may theoretically interfere with estrogen replacement therapy by competing with its effects, and may increase the effects and side effects of carbamazepine (an anti-seizure medication).
Although these are theoretical concerns based on lab findings rather than widespread human reports, the sheer number of medications affected makes it important to check your specific prescriptions before starting. Altogether, these interactions span 827 individual medications.
Use the search tool below to look up your exact drugs, and discuss the results with your doctor or pharmacist before you begin taking this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Trans-Resveratrol 100 Milligrams?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Trans-Resveratrol 100 Milligrams interact with 826 drugs. Click any drug to see the details.
1 of the 1 ingredient in Trans-Resveratrol 100 Milligrams interact with drugs. Each result below shows which ingredient is responsible. Trans-Resveratrol
Acetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Trans-resveratrol + Acetaminophen, Oxycodone interactionPolygonum Cuspidatum ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Pamabrom, Pyrilamine interactionTrans-resveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Trans-resveratrol + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Pentazocine interactionTrans-resveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Trans-resveratrol + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Trans-resveratrol + Acetaminophen, Phenylephrine, Chlorpheniramine interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Trans-resveratrol + Acetaminophen, Phenylpropanolamine interactionPolygonum Cuspidatum ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionTrans-resveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Trans-resveratrol + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Trans-resveratrol + Acetaminophen, Phenyltoloxamine interactionPolygonum Cuspidatum ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Trans-resveratrol + Acetaminophen, Phenyltoloxamine, Salicylamide interactionPolygonum Cuspidatum ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Propoxyphene interactionTrans-resveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Trans-resveratrol + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Trans-resveratrol + Acetaminophen, Pseudoephedrine interactionPolygonum Cuspidatum ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2E1.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Polygonum Cuspidatum Extract + Acetaminophen, Pseudoephedrine, Triprolidine interactionTrans-resveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Trans-resveratrol + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Polygonum Cuspidatum Extract + Acetylsalicylic Acid interactionTrans-resveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Trans-resveratrol + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Adagrasib interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP2C19.
Read the full Polygonum Cuspidatum Extract + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionTrans-resveratrolCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
Read the full Trans-resveratrol + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
Read the full Trans-resveratrol + Agomelatine interactionPolygonum Cuspidatum ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Polygonum Cuspidatum Extract + Agomelatine interactionAlfentanilAlfenta
How Alfentanil interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Alfentanil interactionTrans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Alfuzosin interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Aliskiren interactionTrans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Aliskiren interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Almotriptan interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Alogliptin interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Alogliptin, Pioglitazone interactionTrans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Alpelisib interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Alprazolam interactionTrans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Alprazolam interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Trans-resveratrol + Alteplase, Tpa interactionPolygonum Cuspidatum ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Polygonum Cuspidatum Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Polygonum Cuspidatum Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionTrans-resveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Trans-resveratrol + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Trans-resveratrol + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionPolygonum Cuspidatum ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hu zhang might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Polygonum Cuspidatum Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Ambrisentan interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Ambrisentan interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Amiodarone interactionPolygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Polygonum Cuspidatum ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP3A4.
Read the full Polygonum Cuspidatum Extract + Amitriptyline interactionTrans-resveratrolCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
Read the full Trans-resveratrol + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Trans-Resveratrol 100 Milligrams — through 2 ingredients. Tap an ingredient for the detail:
Trans-resveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Trans-resveratrol + Amitriptyline, Chlordiazepoxide interactionPolygonum Cuspidatum ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Moderate
Interaction Summary
Theoretically, hu zhang might increase levels of drugs metabolized by CYP1A2.
Read the full Polygonum Cuspidatum Extract + Amitriptyline, Chlordiazepoxide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Trans-Resveratrol 100 Milligrams with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Trans-Resveratrol
Anticoagulant/Antiplatelet Drugs
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.
Brand information
Manufacturer and brand details for Trans-Resveratrol 100 Milligrams, from the product label.
NutraBio
See all NutraBio products- Name
- NutraBio Labs, Inc.
- Street Address
- 564 Lincoln Blvd.
- City
- Middlesex
- State
- NJ
- ZipCode
- 08846
- Phone Number
- 732-748-8606
- Web Address
- www.nutrabio.com
Trans-Resveratrol 100 Milligrams by NutraBio: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Trans-Resveratrol 100 Milligrams’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Resveratrol
Interacts with 822 drugsResveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...
Read the full Resveratrol monograph → Herb & supplement monographHu Zhang
Interacts with 826 drugsHu Zhang (Japanese knotweed root) is a traditional Chinese herb that is one of the richest natural sources of resveratrol and emodin. Some lab and early human research looks interesting for...
Read the full Hu Zhang monograph →Sources & How We Checked
Trans-Resveratrol 100 Milligrams's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 43 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Resveratrol 24 references
- Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
- Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
- Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
- Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
- Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
- Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
- Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
- Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
- Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
- Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
- Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
- Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
- Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
- Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
- la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
- Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
- Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
- Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
- Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
- Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
- Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
- McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
- Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
- Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.
Hu Zhang 19 references
- Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
- Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
- Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
- Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
- Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
- Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
- Matsuda H, Shimoda H, Morikawa T, Yoshikawa M. Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorg Med Chem Lett 2001;11:1839-42. PubMed
- Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
- Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
- Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
- Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
- Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
- Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
- Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
- Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
- Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
- Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
- Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
- Chi YC, Lin SP, Hou YC. A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats. Toxicol Appl Pharmacol 2012;263(3):315-22. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC