Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Udo's Oil 3-6-9 Blend Ingredients & Drug Interactions

by Flora Udo's Choice

Udo's Oil 3-6-9 Blend label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Udo's Oil 3-6-9 Blend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Udo's Oil 3-6-9 Blend is a dietary supplement by Flora Udo's Choice with 3 active ingredients. Its ingredients are commonly taken for brain and cognitive health, eye and vision health, fetal and infant development.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Omega-3 Fatty Acids. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Udo's Oil 3-6-9 Blend by Flora Udo's Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Udo's Oil 3-6-9 Blend by Flora Udo's Choice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Udo's Oil 3-6-9 Blend by Flora Udo's Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This blend contains 5 active ingredients: Omega-3 Fatty Acids, Omega-6 Fatty Acids, Omega-9 Fatty Acids, Polyunsaturated Fat, and Monounsaturated Fat. Together they supply a balance of essential fatty acids — the ones your body needs but can't make on its own.

The inactive ingredients include plant oils (flaxseed, sunflower, sesame, coconut, evening primrose, rice bran, oat bran), soy lecithin, mixed tocopherols (a form of vitamin E), and food additives to preserve and deliver the softgel.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: balanced omega-3 and omega-6 essential fatty acids.
  • We looked for evidence on: Cardiovascular disease (CVD), Hyperlipidemia, Hypertension, inflammation, joint health, skin health — and 1 related terms.
  • The strongest evidence on file: Docosahexaenoic Acid (dha) is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Omega-6 Fatty Acids is rated "Possibly Ineffective" for Cardiovascular disease (CVD), Hyperlipidemia.
  • Also on file: Omega-6 Fatty Acids is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

The evidence for omega-6 fatty acids in this product is limited. Studies show it's possibly ineffective for high cholesterol (hyperlipidemia), heart disease, multiple sclerosis, and child development.

We don't have effectiveness ratings on file for the omega-3, omega-9, or other fatty acid components in this blend.

The evidence, ingredient by ingredient Docosahexaenoic Acid (dha) Omega-6 Fatty Acids

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Omega-6 fatty acids from food are fine, but the safety of concentrated supplements isn't well established. The data notes that a higher ratio of omega-6 to omega-3 in your diet may increase the risk of heart disease compared to a lower ratio — so balance matters.

Some research links high omega-6 intake to increased depressive symptoms and, in population studies, possibly increased cancer risk, though the role is unclear. For pregnancy and breastfeeding, omega-6 has mixed safety data: one source rates it likely safe, another possibly unsafe — talk with your doctor or pharmacist about whether this is right for you during pregnancy or nursing.

Side effects, ingredient by ingredient Docosahexaenoic Acid (dha) Omega-6 Fatty Acids

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Docosahexaenoic Acid (dha).
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 375 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

No interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a straightforward essential fatty acid blend with no documented drug interactions. It's generally well tolerated, but the evidence that it works for any specific condition is weak.

If you're considering it for heart health or another reason, run it by your pharmacist first — they can help you weigh the benefit against the uncertain evidence and make sure it fits your overall plan.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Udo's Oil 3-6-9 Blend, straight from the product label.

Brand Flora Udo's Choice
Barcode (UPC) 061998615805
Net contents 90 Vegetarian Softgel(s)
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 304750
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Udo's Oil 3-6-9 Blend by Flora Udo's Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
45
UPC/BARCODE
061998615805
IngredientAmount% DV
Calories20 Calorie(s)--
Calories from Fat20 Calorie(s)--
Omega-3 Fatty Acids840 mg--
Omega-6 Fatty Acids420 mg--
Omega-9 Fatty Acids350 mg--
Total Fat2 Gram(s)3%
Polyunsaturated Fat1.5 Gram(s)--
Monounsaturated Fat0.5 Gram(s)--

Other ingredients: Flaxseed Oil, Sunflower Seed Oil, Sesame Seed Oil, Coconut Oil, Evening Primrose Seed Oil, Rice Bran Oil, Soy Lecithin, Oat Bran Oil, Mixed Tocopherols, Food Starch, Modified, Carrageenan, Glycerin, Sorbitol, Water, Caramel

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Udo's Oil 3-6-9 Blend provides a balanced 2:1 ratio of omega-3 (840 mg) to omega-6 (420 mg) essential fatty acids per serving, for people who want one product that gives them all of the good fats they need, without any of the bad fats they should avoid. Every cell, tissue, gland, and organ is dependent upon the presence of essential fatty acids. They are the main structural component of cell membranes and are important for cell growth and division.

Provides a balanced 2:1:1 ratio of omega fatty acids Made with flax, sesame, sunflower, and other seed oils

GreenCaps+ 14 softgels are equivalent to 1 tbsp. of Udo's Oil 3-6-9 Blend.

Plant based omega-3 fish free

Kosher Check

Formulation

Udo's Oil 3-6-9 Blend provides a balanced 2:1 ratio of omega-3 (840 mg) to omega-6 (420 mg) essential fatty acids per serving, for people who want one product that gives them all of the good fats they need, without any of the bad fats they should avoid.

Udo's oil blend is fresh-pressed in a state-of-the-art, low heat, light- and oxygen-free environment and packaged in an environmentally friendly glass bottle.

Gluten free!

Non GMO Project Verified nongmoproject.org

Product of USA

General Statements

Udo's Oil is formulated by Udo Erasmus, PhD, an internationally acclaimed authority on the subject of essential fatty acids and author of the groundbreaking book Fats That Heal Fats That Kill.

Try the other Udo's Choice products to enhance your health and well-being: Age- & condition-specific probiotics Fiber-rich wholesome fast food Age- & condition-specific enzymes Nutrient-rich green blend Formulated by: Udo Erasmus, PhD. Udo Erasmus

Seals/Symbols

Non GMO Project Verified nongmoproject.org

Kosher Check

FDA Statement of Identity

Dietary Supplement

Precautions

Caution: Manufactured in a facility that also processes mustard and wheat.

Keep out of reach of children.

Security sealed for your protection. Do not use if seal is missing or damaged.

Suggested/Recommended/Usage/Directions

Suggested use: Take 2 softgels three times a day with meals.

Udo's Oil 3-6-9 blend softgels are ideal for travelers and people on the go as a "maintenance use" omega fatty acid supplement. For best results, use Udo's Oil 3-6-9 blend in liquid form and take 1 tbsp. or more per day with meals (up to 1 tbsp. per 50 lb. of body weight per day).

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Udo's Oil 3-6-9 Blend by Flora Udo's Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Udo's Oil 3-6-9 Blend label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Udo's Oil 3-6-9 Blend by Flora Udo's Choice

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Omega-3 Fatty Acids

Interacts with
375 drugs
840 mg per serving

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...

Omega-3 Fatty Acids monograph & interactions

Omega-6 Fatty Acids

No known
interactions
420 mg per serving

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils,...

Omega-6 Fatty Acids monograph & interactions

Omega-9 Fatty Acids

350 mg per serving

Other (inactive) ingredients: Flaxseed Oil, Sunflower Seed Oil, Sesame Seed Oil, Coconut Oil, Evening Primrose Seed Oil, Rice Bran Oil, Soy Lecithin, Oat Bran Oil, Mixed Tocopherols, Food Starch, Modified, Carrageenan, Glycerin, Sorbitol, Water, Caramel. These complete the product’s ingredient list but are not active constituents.

Interaction report

Udo's Oil 3-6-9 Blend by Flora Udo's Choice Drug Interactions

Want to check YOUR meds against Udo's Oil 3-6-9 Blend?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
375Drugs
375 Moderate

Ingredients driving the most interactions

Omega-3 Fatty Acids 375

Individual Drug Interactions

The ingredients in Udo's Oil 3-6-9 Blend interact with 375 drugs. Click any drug to see the details.

1 of the 3 ingredients in Udo's Oil 3-6-9 Blend interact with drugs. Each result below shows which ingredient is responsible. Omega-3 Fatty Acids

Each ingredient & the kinds of drugs it affects

For each ingredient in Udo's Oil 3-6-9 Blend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Omega-3 Fatty Acids3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.

Likelihood Probable Evidence B
Omega-3 Fatty Acids full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Udo's Oil 3-6-9 Blend, from the product label.

Flora Udo's Choice

See all Flora Udo's Choice products
Name
Flora, Inc.
Street Address
805 E. Badger Rd.
City
Lynden
State
WA
ZipCode
98264
Phone Number
1.800.446.2110
Web Address
www.florahealth.com
Pharmacist Counseling Corner

Udo's Oil 3-6-9 Blend by Flora Udo's Choice: Common Questions

Does Udo's Oil 3-6-9 Blend by Flora Udo's Choice interact with any medications?
Yes. Based on its ingredients, Udo's Oil 3-6-9 Blend has a known interaction with 375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Udo's Oil 3-6-9 Blend contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
The data is mixed — one source rates omega-6 as likely safe, another as possibly unsafe. There isn't enough consistent information to say either way. Talk with your doctor or pharmacist before taking this while pregnant or nursing; they can give you personalized advice based on your health.
Does this product actually help with heart health or cholesterol?
For omega-6 fatty acids specifically, the evidence shows it's possibly ineffective for high cholesterol and heart disease. We don't have effectiveness data on file for the other fatty acids in the blend. It's worth discussing with your doctor whether this is the right choice for your goals.
What's the difference between omega-3, omega-6, and omega-9?
They're all types of fatty acids your body uses, but omega-3 and omega-6 are essential — your body can't make them, so you need to get them from food or supplements. Omega-9 is non-essential; your body can make it. This blend aims to give you a balance of all three.
Can I take this if I'm already eating a lot of omega-6 from my diet?
That's a good question. The data notes that a higher ratio of omega-6 to omega-3 in your diet may not be ideal for heart health, and most people already get plenty of omega-6 from food. Check with your pharmacist or doctor about whether adding a supplement makes sense for you.
What are the inactive ingredients in this softgel?
The softgel contains plant oils (flaxseed, sunflower, sesame, coconut, evening primrose, rice bran, and oat bran), soy lecithin, mixed tocopherols, and food additives like carrageenan, glycerin, sorbitol, and modified food starch to hold it together and keep it stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Udo's Oil 3-6-9 Blend is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Udo's Oil 3-6-9 Blend label
Go deeper

The Full Monographs Behind Udo's Oil 3-6-9 Blend’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Docosahexaenoic Acid (dha)

Interacts with 375 drugs

DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and generally well tolerated, with the stronges...

Read the full Docosahexaenoic Acid (dha) monograph → Herb & supplement monograph

Omega-6 Fatty Acids

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils, nuts, and seeds. Supplements such as ev...

Read the full Omega-6 Fatty Acids monograph →
Sources

Sources & How We Checked

Udo's Oil 3-6-9 Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 69 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Docosahexaenoic Acid (dha) 49 references
  1. Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
  2. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  3. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  4. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  5. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  6. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  7. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  8. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  9. Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
  10. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
  11. Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
  12. Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
  13. Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
  14. Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
  15. Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
  16. Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
  17. Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Supplementation with docosahexaenoic acid in the last trimester of pregnancy: maternal-fetal biochemical findings. J Perinat Med 2004;32:132-6.
  18. Montgomery C, Speake BK, Cameron A, et al. Maternal docosahexaenoic acid supplementation and fetal accretion. Br J Nutr 2003;90:135-45. DOI
  19. Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Pediatr Res 2005;58:235-42. PubMed
  20. Hawkes JS, Bryan DL, Makrides M, et al. A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha. Am J Clin Nutr 2002;75:75
  21. Uauy R, Hoffman DR, Mena P, et al. Term infant studies of DHA and ARA supplementation on neurodevelopment: Results of randomized controlled trials. J Pediatr 2003;143:S17-25. PubMed
  22. Decsi, T., Campoy, C., and Koletzko, B. Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. Adv.Exp Med Biol 2005;569:109-113. PubMed
  23. Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 1999;34(2):253-260. PubMed
  24. Otto, S. J., van Houwelingen, A. C., and Hornstra, G. The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. Prostaglandins Le PubMed
  25. Helland, I. B., Saugstad, O. D., Smith, L., Saarem, K., Solvoll, K., Ganes, T., and Drevon, C. A. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001;108(5):E82. PubMed
  26. Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., and Raederstorff, D. The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am.J.Clin.Nutr. 2002;76(2):326-330. PubMed
  27. Woodman, R. J., Mori, T. A., Burke, V., Puddey, I. B., Barden, A., Watts, G. F., and Beilin, L. J. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients PubMed
  28. Jensen, C. L., Voigt, R. G., Prager, T. C., Zou, Y. L., Fraley, J. K., Rozelle, J. C., Turcich, M. R., Llorente, A. M., Anderson, R. E., and Heird, W. C. Effects of maternal docosahexaenoic acid intake on visual function and neurodevelopment in breastfed
  29. Theobald, H. E., Goodall, A. H., Sattar, N., Talbot, D. C., Chowienczyk, P. J., and Sanders, T. A. Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and women. J Nutr 2007;137(4):973-978.
  30. Mischoulon D, Best-Popescu C, Laposata M, et al. A double-blind dose-finding pilot study of docosahexaenoic acid (DHA) for major depressive disorder. Eur Neuropsychopharmacol. 2008;18(9):639-645. PubMed
  31. Birch EE, Carlson SE, Hoffman DR, et al. The DIAMOND (DHA Intake And Measurement Of Neural Development) Study: a double-masked, randomized controlled clinical trial of the maturation of infant visual acuity as a function of the dietary level of docosahexa
  32. Carlson SE, Colombo J, Gajewski BJ, Gustafson KM, Mundy D, Yeast J, Georgieff MK, Markley LA, Kerling EH, Shaddy DJ. DHA supplementation and pregnancy outcomes. Am J Clin Nutr. 2013 Apr;97(4):808-15. PubMed
  33. Escamilla-Nuñez MC, Barraza-Villarreal A, Hernández-Cadena L, Navarro-Olivos E, Sly PD, Romieu I. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children. Chest. 2014 Aug;146(2):373-82. PubMed
  34. Fu YQ, Zheng JS, Yang B, Li D. Effect of individual omega-3 fatty acids on the risk of prostate cancer: a systematic review and dose-response meta-analysis of prospective cohort studies. J Epidemiol. 2015;25(4):261-74. PubMed
  35. Imhoff-Kunsch B, Stein AD, Villalpando S, Martorell R, Ramakrishnan U. Docosahexaenoic acid supplementation from mid-pregnancy to parturition influenced breast milk fatty acid concentrations at 1 month postpartum in Mexican women. J Nutr. 2011 Feb;141(2): PubMed
  36. Judge MP, Cong X, Harel O, Courville AB, Lammi-Keefe CJ. Maternal consumption of a DHA-containing functional food benefits infant sleep patterning: an early neurodevelopmental measure. Early Hum Dev. 2012 Jul;88(7):531-7. PubMed
  37. Mulder KA, King DJ, Innis SM. Omega-3 fatty acid deficiency in infants before birth identified using a randomized trial of maternal DHA supplementation in pregnancy. PLoS One. 2014 Jan 10;9(1):e83764. PubMed
  38. Richardson AJ, Burton JR, Sewell RP, Spreckelsen TF, Montgomery P. Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study). PLoS One. 2012;7(9):e43909. PubMed
  39. Drugs in Pregnancy and Lactation 2012;25(4);3-4
  40. FDA announces qualified health claims for omega-3 fatty acids. Available at: https://www.fda.gov/Food/LabelingNutrition/ucm072756.htm. Accessed April 15 2019.
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  42. Zhang Z, Fulgoni VL, Kris-Etherton PM, Mitmesser SH. Dietary Intakes of EPA and DHA Omega-3 Fatty Acids among US Childbearing-Age and Pregnant Women: An Analysis of NHANES 2001-2014. Nutrients. 2018;10(4). PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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