Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Ultimate Flora Probiotic Gummies 2 Billion Ingredients & Drug Interactions

by Renew Life

Ultimate Flora Probiotic Gummies 2 Billion label
See full label image
Gummy Or Jelly Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ultimate Flora Probiotic Gummies 2 Billion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ultimate Flora Probiotic Gummies 2 Billion is a dietary supplement by Renew Life with 2 active ingredients. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus coagulans probiotic. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ultimate Flora Probiotic Gummies 2 Billion by Renew Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Ultimate Flora Probiotic Gummies 2 Billion by Renew Life — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ultimate Flora Probiotic Gummies 2 Billion by Renew Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Ultimate Flora Probiotic Gummies 2 Billion contains one active ingredient: Bacillus coagulans, a probiotic strain—live beneficial bacteria meant to support digestive health. The inactive ingredients include natural fruit juice, cane sugar, glucose syrup, gelatin, citric acid, natural flavors, color, and coconut oil.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Bacillus Coagulans's overall clinical evidence instead.

Moderate

Some clinical evidence supports Bacillus Coagulans for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Constipation — rated "Possibly Effective" (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Natural Medicines).

The evidence for Bacillus coagulans in this product shows it's possibly effective for constipation and irritable bowel syndrome (IBS). For antibiotic-associated diarrhea, athletic performance, cancer, and nonalcoholic fatty liver disease, the evidence isn't established in our data—there isn't enough reliable information to rate how well it works.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus coagulans is generally well tolerated in healthy adults, but safety data and product quality vary across brands. There isn't enough reliable safety information overall, so talk to your doctor before starting this product.

One concern: because it contains live organisms, there's a theoretical risk of infection in people with central lines, severe illness, or weakened immune systems—including premature infants. Healthy people with intact immunity appear to be at very low risk, but it's worth discussing with your doctor if you fall into a higher-risk group.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antibiotics, check with your doctor or pharmacist about timing—antibiotics can interfere with how well this probiotic works, so you may need to space them apart. No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may help with constipation or IBS symptoms. If you take antibiotics, space them out from this supplement to keep the probiotic working.

Before you start, especially if you're severely ill, immunocompromised, or have a central line, talk it over with your doctor or pharmacist to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultimate Flora Probiotic Gummies 2 Billion, straight from the product label.

Brand Renew Life
Net contents 2 Natural Flavored Gummie(s)
Market status On market
Date entered into DSLD Mar 24, 2017
DSLD ID 72325
Product type Non-nutrient/non-botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Seniors/Mature (>50 Years), Dairy Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultimate Flora Probiotic Gummies 2 Billion by Renew Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummie(s)
Maximum serving Sizes:
2 Gummie(s)
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Sugar3 Gram(s)--
Bacillus coagulans probiotic0 NP--

Other ingredients: natural Fruit Juice, Cane Sugar, Glucose Syrup, Gelatin, Citric Acid, Natural Flavors, Color, Coconut Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Dairy free Soy free No artificial ingredients

General Statements

Quality, purity, and potency guaranteed through expiration.

Manufactured in Australia in a GMP facility.

Sample packet not for individual sale

2 billion live cultures per serving ~ Promotes digestive balance ~ Supports immune health

90894A

Precautions

Keep out of reach of children.

Consult your healthcare professional before using this or any product if you are pregnant, nursing, or under medical supervision.

Children should be under adult supervision when consuming this product.

Tamper Evident: Do not use if packet is open

Not for children under 2 years of age due to the risk of choking.

Contains wheat, tree nuts (coconut).

General

#15692 011015

Formula

For kids ages 2-102

Contains wheat, tree nuts (coconut).

FDA Statement of Identity

Probiotic Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Adults and children 2 and up, chew two gummies daily.

Storage

Store in a dry place at 77(0)F (25(0)C) or below.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ultimate Flora Probiotic Gummies 2 Billion by Renew Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ultimate Flora Probiotic Gummies 2 Billion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ultimate Flora Probiotic Gummies 2 Billion by Renew Life

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummie(s) Dosage formGummy Or Jelly Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

3 Gram(s) per serving

Bacillus coagulans probiotic

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

Bacillus coagulans probiotic monograph & interactions

Other (inactive) ingredients: Natural Fruit Juice, Cane Sugar, Glucose Syrup, Gelatin, Citric Acid, Natural Flavors, Color, Coconut Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ultimate Flora Probiotic Gummies 2 Billion by Renew Life Drug Interactions

Want to check YOUR meds against Ultimate Flora Probiotic Gummies 2 Billion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bacillus coagulans probiotic 182

Individual Drug Interactions

The ingredients in Ultimate Flora Probiotic Gummies 2 Billion interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in Ultimate Flora Probiotic Gummies 2 Billion interact with drugs. Each result below shows which ingredient is responsible. Bacillus coagulans probiotic

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultimate Flora Probiotic Gummies 2 Billion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus coagulans probiotic1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans probiotic full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ultimate Flora Probiotic Gummies 2 Billion, from the product label.

Renew Life

Name
Renew Life Formulas
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Web Address
www.ultimateflora.com
Pharmacist Counseling Corner

Ultimate Flora Probiotic Gummies 2 Billion by Renew Life: Common Questions

Does Ultimate Flora Probiotic Gummies 2 Billion by Renew Life interact with any medications?
Yes. Based on its ingredients, Ultimate Flora Probiotic Gummies 2 Billion has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultimate Flora Probiotic Gummies 2 Billion contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my antibiotics?
Taking antibiotics and this probiotic at the same time can reduce the probiotic's effectiveness, because antibiotics kill the live organisms. Talk to your doctor or pharmacist about spacing them out—they can recommend how far apart to take them.
Does this really help with IBS or constipation?
The evidence shows Bacillus coagulans is possibly effective for both IBS and constipation, meaning there's some support but it's not definitive. Results vary between people.
Is this safe for most people?
It's generally well tolerated in healthy adults. However, safety data vary, and there's a theoretical risk of infection in people with weakened immune systems or central lines. Talk to your doctor first if you're severely ill or immunocompromised.
What are the inactive ingredients?
The inactive ingredients include natural fruit juice, cane sugar, glucose syrup, gelatin, citric acid, natural flavors, color, and coconut oil.
Is there enough data on safety during pregnancy or breastfeeding?
The safety data on file doesn't include pregnancy or breastfeeding information for this ingredient. Talk with your doctor or pharmacist before using it if you're pregnant or nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultimate Flora Probiotic Gummies 2 Billion is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultimate Flora Probiotic Gummies 2 Billion label
Go deeper

The Full Monographs Behind Ultimate Flora Probiotic Gummies 2 Billion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Ultimate Flora Probiotic Gummies 2 Billion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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