Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Ultra Cordyceps Ingredients & Drug Interactions

by Doctor's Best

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Ultra Cordyceps is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 282 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Cordyceps sinensis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Ultra Cordyceps by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Cordyceps sinensis” is listed as a grouped ingredient — the label gives one combined amount (750 mg) without saying how much of each component you get.

Ultra Cordyceps supplies two active ingredients: Cordyceps sinensis (a fungal extract) and 8% cordycepic acid. The product also contains inactive ingredients — modified cellulose, cellulose, and magnesium silicate — which are binders and capsule material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Adenosine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: improves energy stamina and vitality.
  • We looked for evidence on: fatigue, athletic performance.
  • The closest evidence on file: Adenosine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

The data we hold on adenosine, one of this product's active ingredients, shows effectiveness for paroxysmal supraventricular tachycardia (a type of rapid heart rhythm) and cardiovascular disease diagnosis. These ratings come from intravenous prescription use, not oral supplement form.

We don't have effectiveness data on file for Cordyceps sinensis or cordycepic acid as a supplement.

The evidence, ingredient by ingredient Cordyceps Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Adenosine's safety profile in oral supplement form is limited and not well established. The prescription injectable form is powerful and carries serious cardiovascular and respiratory risks — intravenous use can cause chest pain, dizziness, shortness of breath, flushing, low blood pressure, heart rhythm problems, and in rare cases, cardiac arrest or heart attack.

Oral or intramuscular adenosine hasn't reported adverse effects in available data, but a thorough safety evaluation hasn't been done. The safety notes advise caution with oral supplements and recommend avoiding this product during pregnancy and breastfeeding due to insufficient safety information.

Side effects, ingredient by ingredient Cordyceps Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Adenosine.
  • The most serious interaction on file is rated Major.
  • For scale: 47 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Ultra Cordyceps, check with your doctor or pharmacist if you take dipyridamole (Persantine) — a Major interaction can cause dizziness, slow heart rate, and fainting. Also check if you take carbamazepine (Tegretol) for a possible Moderate risk of heart block.

Finally, avoid caffeine, theophylline, and aminophylline for 24 hours before use, as they can block adenosine's effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

This product is marketed as a cordyceps supplement, but it contains adenosine — a prescription cardiac drug in injectable form — whose oral supplement safety and effectiveness aren't well established. If you take dipyridamole, carbamazepine, or methylxanthines like caffeine or theophylline, talk with your doctor or pharmacist before starting it.

For personalized advice on whether this is right for you, check with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultra Cordyceps, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950002678
Net contents 10 Veggie Cap(s)
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 25545
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultra Cordyceps by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
10
UPC/BARCODE
753950002678
IngredientAmount% DV
Cordyceps sinensis750 mg--
Supplying 8% cordycepic acid60 mg--
0.3 adenosine2 mg--

Other ingredients: Modified Cellulose, Cellulose, Magnesium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General

_P 06/11

General Statements

IMPROVES ENERGY, STAMINA & VITALITY*

CONTAINS NOTHING OTHER THAN LISTED INGREDIENTS

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 to 4 capsules daily, with or without food.

Precautions

Note: Cordyceps has mild blood-thinning properties. Use with caution when taking anti-coagulant (blood thinning) medications.

Keep out of reach of children.

Formulation

Suitable for Vegetarians

Brand IP Statement(s)

Science-Based Nutrition(TM)

FDA Statement of Identity

Dietary Supplement

See for yourself

Ultra Cordyceps by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Ultra Cordyceps by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container10 Amounts shown are per serving.

Cordyceps sinensis

Interacts with
249 drugs
750 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps sinensis monograph & interactions

Other (inactive) ingredients: Modified Cellulose, Cellulose, Magnesium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ultra Cordyceps by Doctor's Best Drug Interactions

Want to check YOUR meds against Ultra Cordyceps?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
282Drugs
2 Major 240 Moderate 40 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultra Cordyceps with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps sinensis3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Ultra Cordyceps, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
City
San Clemente
State
CA
ZipCode
92673
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Ultra Cordyceps by Doctor's Best: Common Questions

Does Ultra Cordyceps by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Ultra Cordyceps has a known interaction with 282 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultra Cordyceps contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's actually in Ultra Cordyceps?
It contains Cordyceps sinensis fungal extract and 8% cordycepic acid as active ingredients. The capsule also has binders and filler materials — modified cellulose, cellulose, and magnesium silicate.
Is this safe to take while pregnant or breastfeeding?
The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know if it's safe. Talk with your doctor or pharmacist about your specific situation.
Why does a cordyceps supplement contain adenosine?
Adenosine is one of the compound's active ingredients. What we know about adenosine comes mainly from its use as a prescription injection for heart conditions, not from oral supplement use, so the oral safety profile isn't fully established.
Can I take this if I drink coffee or tea?
Caffeine blocks adenosine's effects, so you should avoid it for 24 hours before taking this product. Black tea and coffee contain caffeine, so plan accordingly.
What side effects might I experience?
Adverse effects haven't been thoroughly studied for the oral supplement form. The prescription injectable form can cause chest pain, dizziness, shortness of breath, flushing, low blood pressure, and heart rhythm problems, but those data don't directly apply to oral use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultra Cordyceps is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultra Cordyceps label
Sources

Sources & How We Checked

Ultra Cordyceps's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring