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Dietary supplement

Umckaloabo Extract Ingredients & Drug Interactions

by NusaPure

Umckaloabo Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Umckaloabo Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Umckaloabo Extract is a dietary supplement by NusaPure with 1 active ingredient. Its ingredients are commonly taken for acute bronchitis, common cold, sinusitis.Based on those ingredients, 241 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Umckaloabo extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Umckaloabo Extract by NusaPure

Ask about any prescription or over-the-counter medication and we check it for interactions with Umckaloabo Extract by NusaPure — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Umckaloabo Extract by NusaPure

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: umckaloabo extract, a traditional herbal remedy made from Pelargonium sidoides, a South African geranium. The capsule also holds inactive ingredients — cellulose, silica, magnesium stearate, microcrystalline cellulose, and rice flour — which are common binders and fillers that help hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: respiratory health and upper respiratory infections.
  • We looked for evidence on: Acute Bronchitis, Upper respiratory tract infection (URTI), Rhinosinusitis, Tonsillopharyngitis, Common cold, Sore throat — and 1 related terms.
  • The strongest evidence on file: Umckaloabo is rated "Possibly Effective" for Acute Bronchitis (Natural Medicines).
  • Also on file: Umckaloabo is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Rhinosinusitis, Tonsillopharyngitis.

Umckaloabo extract is possibly effective for acute bronchitis and chronic obstructive pulmonary disease (COPD), meaning there's some evidence it may help with these conditions, though the research isn't conclusive. For tonsillopharyngitis (sore throat and tonsil inflammation), there isn't enough reliable evidence to say whether it works.

The evidence we have comes from clinical trials, but more research would strengthen our confidence.

The evidence, ingredient by ingredient Umckaloabo

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Umckaloabo extract is generally well tolerated for short-term use. The most common side effects are allergic skin rash, diarrhea, and gastrointestinal upset.

It doesn't appear to damage the liver, though quality and standardization vary by product, so that can affect how it affects you. During pregnancy, safety has not been established, so it's best avoided.

While breastfeeding, there isn't enough safety information, so you should avoid it as well.

Side effects, ingredient by ingredient Umckaloabo

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Umckaloabo.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 241 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take immunosuppressants (a Moderate interaction) — umckaloabo may reduce their effectiveness. Also double-check if you're on blood thinners or antiplatelet drugs like warfarin or aspirin (Minor interaction), though the practical risk appears lower than the theory suggests.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have acute bronchitis or COPD and want to try an herbal approach, umckaloabo is a candidate — the evidence suggests it might help. However, if you take immunosuppressants or blood thinners, you'll need to check with your pharmacist first.

Avoid it in pregnancy and while breastfeeding. It's generally mild on the stomach for most people, but watch for rash or diarrhea.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Umckaloabo Extract, straight from the product label.

Brand NusaPure
Barcode (UPC) X001O7W6WT
Net contents 200 Veg Cap(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 247055
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Umckaloabo Extract by NusaPure, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
100
UPC/BARCODE
X001O7W6WT
IngredientAmount% DV
Umckaloabo extract60 mg--

Other ingredients: Cellulose, Silica, Magnesium Stearate, Microcrystalline Cellulose, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one (1) or two (2) capsules daily, preferably with a meal.

Precautions

Warning: For adults only.

If you are pregnant, nursing, or taking any medication (especially antiplatelet, anticoagulant drugs, aspirin and NSAIDs), or have a medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

Allergen Information: Contains no artificial coloring, artificial flavors, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Assembled in USA Natural Healthy respiratory & immune support Support healthy sinus, nasal & bronchial function Max Strength

Allergen Information: Contains no artificial coloring, artificial flavors, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

Storage

Store in a cool, dry place after opening.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Premium Quality Assembled in USA GMO Free Made with non-GMO Ingredients Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility

Formula

Umckaloabo extract 240 mg equivalent per serving

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Umckaloabo Extract by NusaPure label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Umckaloabo Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Umckaloabo Extract by NusaPure

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Umckaloabo extract

Interacts with
241 drugs
60 mg per serving

Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respiratory infect...

Umckaloabo extract monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Magnesium Stearate, Microcrystalline Cellulose, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Umckaloabo Extract by NusaPure Drug Interactions

Want to check YOUR meds against Umckaloabo Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
241Drugs
121 Moderate 120 Minor

Ingredients driving the most interactions

Umckaloabo extract 241

Individual Drug Interactions

The ingredients in Umckaloabo Extract interact with 241 drugs. Click any drug to see the details.

1 of the 1 ingredient in Umckaloabo Extract interact with drugs. Each result below shows which ingredient is responsible. Umckaloabo extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Umckaloabo Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Umckaloabo extract2 drug types · 241 drugs

Immunosuppressants

Theoretically, Pelargonium sidoides might decrease the effectiveness of immunosuppressant therapy.
In vitro research suggests that Pelargonium sidoides has immunostimulant effects.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, Pelargonium sidoides might increase the risk of bleeding when taken with anticoagulant and antiplatelet drugs.
Pelargonium sidoides contains coumarin, which may reduce platelet aggregation. However, in animal models, Pelargonium sidoides extract does not appear to inhibit coagulation or interact with warfarin. This interaction has not been documented in humans.

Likelihood Unlikely Evidence D
Umckaloabo extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Umckaloabo Extract, from the product label.

NusaPure

See all NusaPure products
Name
Gmax Central LLC
Street Address
4700 Millenia Boulevard, Suite 175 PMB 92909
City
Orlando
State
FL
ZipCode
32839
Pharmacist Counseling Corner

Umckaloabo Extract by NusaPure: Common Questions

Does Umckaloabo Extract by NusaPure interact with any medications?
Yes. Based on its ingredients, Umckaloabo Extract has a known interaction with 241 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Umckaloabo Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Umckaloabo theoretically might increase bleeding risk with warfarin because it contains coumarin. However, animal studies found it doesn't actually inhibit blood clotting or interact with warfarin itself. Still, this is one you should run by your pharmacist before adding — they can check your specific situation.
Is it safe to take while breastfeeding?
No — there isn't enough safety information available, so it's best to avoid umckaloabo while breastfeeding. Talk with your doctor or pharmacist if you're wondering about alternatives.
Can I take this if I'm pregnant?
No — safety has not been established during pregnancy, so it's best avoided. If you're pregnant or planning to become pregnant, talk with your doctor about other options.
What are the side effects?
Most side effects are mild. The most common are allergic skin rash, diarrhea, and gastrointestinal upset. It doesn't appear to damage your liver. Overall it's generally well tolerated, especially for short-term use.
Does umckaloabo actually work for bronchitis?
For acute bronchitis, the evidence suggests it's possibly effective — meaning there's some research backing it, but it's not definitive. For COPD, it's also possibly effective. For sore throat (tonsillopharyngitis), there isn't enough reliable evidence to say whether it helps.
Will this interfere with my immunosuppressant medication?
Possibly yes — umckaloabo has immune-stimulating effects, which theoretically could make your immunosuppressant weaker. This is a Moderate-severity interaction, so check with your pharmacist before adding this supplement to your routine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Umckaloabo Extract label
Go deeper

The Full Monographs Behind Umckaloabo Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Umckaloabo

Interacts with 241 drugs

Umckaloabo is a root extract from a South African geranium that is most studied for short-term relief of acute bronchitis and other respiratory infections. Some clinical research suggests it...

Read the full Umckaloabo monograph →
Sources

Sources & How We Checked

Umckaloabo Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Umckaloabo 16 references
  1. Chuchalin AG, Berman B, Lehmacher W. Treatment of acute bronchitis in adults with a pelargonium sidoides preparation (EPs 7630): A randomized, double-blind, placebo-controlled trial. Explore 2005;1:437-45. PubMed
  2. Kolodziej H, Kayser O, Radtke OA, et al. Pharmacological profile of extracts of Pelargonium sidoides and their constituents. Phytomedicine 2003;10 Suppl 4:18-24. PubMed
  3. Bereznoy VV, Riley DS, Wassmer G, Heger M. Efficacy of extract of Pelargonium sidoides in children with acute non-group A beta-hemolytic streptococcus tonsillopharyngitis: a randomized, double-blind, placebo-controlled trial. Altern Ther Health Med 2003;9
  4. Kolodziej H, Kiderlen AF. In vitro evaluation of antibacterial and immunomodulatory activities of Pelargonium reniforme, Pelargonium sidoides and the related herbal drug preparation EPs 7630. Phytomedicine 2007;14 Suppl 6:18-26. PubMed
  5. Koch E, Biber A. Treatment of rats with the Pelargonium sidoides extract EPs 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin. Phytomedicine 2007;14 Suppl 6:40-5. PubMed
  6. Conrad A, Hansmann C, Engels I, et al. Extract of Pelargonium sidoides (EPs 7630) improves phagocytosis, oxidative burst, and intracellular killing of human peripheral blood phagocytes in vitro. Phytomedicine 2007;14 Suppl 6:46-51. PubMed
  7. Matthys H, Kamin W, Funk P, Heger M. Pelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and children. Phytomedicine 2007;14 Suppl 6:69-73. PubMed
  8. Conrad A, Jung I, Tioua D, et al. Extract of Pelargonium sidoides (EPs 7630) inhibits the interactions of group A-streptococci and host epithelia in vitro. Phytomedicine 2007;14 Suppl 6:52-9. PubMed
  9. Matthys, H., Eisebitt, R., Seith, B., and Heger, M. Efficacy and safety of an extract of Pelargonium sidoides (EPs 7630) in adults with acute bronchitis. A randomised, double-blind, placebo-controlled trial. Phytomedicine 2003;10 Suppl 4:7-17. PubMed
  10. de Boer, H. J., Hagemann, U., Bate, J., and Meyboom, R. H. Allergic reactions to medicines derived from Pelargonium species. Drug Saf 2007;30(8):677-680. PubMed
  11. Teschke R, Frenzel C, Schulze J, Eickhoff A. Spontaneous reports of primarily suspected herbal hepatotoxicity by Pelargonium sidoides: was causality adequately ascertained? Regul Toxicol Pharmacol 2012;63(1):1-9. PubMed
  12. Teschke R, Frenzel C, Wolff A, et al. Initially purported hepatotoxicity by Pelargonium sidoides: the dilemma of pharmacovigilance and proposals for improvement. Ann Hepatol 2012;11(4):500-12. DOI
  13. Riley DS, Lizogub VG, Zimmermann A, Funk P, Lehmacher W. Efficacy and tolerability of high-dose Pelargonium extract in patients with the common cold. Altern Ther Health Med 2018;24(2):16-26.
  14. Matthys H, Pliskevich DA, Bondarchuk OM, Malek FA, Tribanek M, Kieser M. Randomised, double-blind, placebo-controlled trial of EPs 7630 in adults with COPD. Respir Med 2013;107(5):691-701. PubMed
  15. Willcox M, Simpson C, Wilding S, et al. Pelargonium sidoides root extract for the treatment of acute cough due to lower respiratory tract infection in adults: a feasibility double-blind, placebo-controlled randomised trial. BMC Complement Med Ther 2021;21 PubMed
  16. Kamin W, Behre U, Helm K, Reling B, Funk P, Malek FA. Safety of Pelargonium extract EPs 7630 in young children with acute bronchitis. Front Pediatr 2023;11:1107984. PubMed

See these in context on the Umckaloabo monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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