Urinary Bladder Support Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Urinary Bladder Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Urinary Bladder Support is a dietary supplement by Hawaii Pharm with 4 active ingredients. Its ingredients are commonly taken for cough and sore throat, dry mouth and throat irritation, digestive upset and heartburn.Based on those ingredients, 2,143 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow Leaf Extract, Dry, Uva Ursi Herb Extract, Dry, Corn Silk Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Urinary Bladder Support by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Urinary Bladder Support by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Urinary Bladder Support by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid formula contains four active plant extracts. Marshmallow leaf extract, corn silk extract, couch grass root extract, and uva ursi herb extract are blended together to support urinary tract health.
The product also includes alcohol, water, and glycerin as inactive ingredients that help preserve and deliver the extracts.
Does it work?
Leans against
The evidence for these ingredients is limited. Marshmallow leaf has insufficient evidence to rate for the conditions it's traditionally used for — including vaginal yeast infections, diarrhea, eczema, and respiratory infections.
Corn silk, too, shows insufficient evidence for its proposed uses like heart disease, diabetes, and fatigue. Uva ursi herb extract is rated possibly ineffective for urinary tract infections, the very condition this product seems designed to address — the data we hold doesn't support its use for that purpose.
Couch grass root has no effectiveness ratings in our data.
How safe is it?
Well-documented data
Marshmallow leaf and corn silk are generally well tolerated for short-term use, though human safety data are limited for both. Uva ursi is also generally well tolerated at low doses in the short term, but can be toxic at high doses or with prolonged use — at very high doses (30 grams or more), it may be fatal.
All three have advised against use during pregnancy due to insufficient safety data. Marshmallow and uva ursi should be avoided while breastfeeding; for corn silk, safety while breastfeeding is unknown, so avoid it unless a doctor approves.
Uva ursi may cause nausea, vomiting, diarrhea, and stomach upset, and at high doses can cause serious effects like convulsions and delirium. Couch grass is considered generally well tolerated but should be avoided in pregnancy and breastfeeding due to limited safety data.
Meds to double-check
Moderate interaction found
Before taking Urinary Bladder Support, check with your pharmacist if you take blood pressure medications (antihypertensives), diabetes medications, corticosteroids, diuretics, or warfarin — corn silk extract has moderate interactions with all of these. Uva ursi may affect medications metabolized by CYP2C19 or CYP3A4 enzymes, glucuronidated drugs, or lithium, and urinary acidifiers can interfere with uva ursi's function.
Marshmallow leaf may impair absorption of oral medications — space them 30–60 minutes apart. If you're on any regular medication, use the checker on this page with your specific drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines four plant extracts aimed at urinary tract support, but the evidence that they work is not established in our data — uva ursi is even rated possibly ineffective for UTIs. If you take blood pressure, diabetes, or blood-thinning medications, or corticosteroids or diuretics, you need to check your exact drugs with the tool below before starting, because corn silk and other ingredients carry documented interactions.
Talk to your pharmacist or doctor about whether this product is right for you and your medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Urinary Bladder Support, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 840253664150 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2023 |
| DSLD ID | 301953 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Urinary Bladder Support by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 983 mg | -- |
| Marshmallow Leaf Extract, Dry | 0 NP | -- |
| Corn Silk Extract, Dry | 0 NP | -- |
| Couch Root Extract, Dry | 0 NP | -- |
| Uva Ursi Herb Extract, Dry | 0 NP | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Hawaii Pharm Herbal Extract Highest quality since 2008
Suggested/Recommended/Usage/Directions
Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.
Precautions
Warning: We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.
Keep out of the reach of children!
Storage
Store in a cool dry place.
Seals/Symbols
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Organic Alcohol Based USA Made in United States of America
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Made in USA, Hawaii
Only natural ingredients Purity is laboratory tested and verified
All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives
Not tested on animals
Organic Alcohol Based
FDA Statement of Identity
Herbal Supplement
Formula
Organic Alcohol Based
General Statements
Scan this QR-code to get 15% discount on your next purchase. Limited time deal
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Urinary Bladder Support by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Urinary Bladder Support by Hawaii Pharm
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Urinary Bladder Support by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Urinary Bladder Support by Hawaii Pharm contains four ingredients, two of which have documented interactions with medications.
The most serious concern is corn silk extract, which can lower blood pressure — if you take blood pressure medications (antihypertensives), combining them with this product could drop your pressure too far.
Read the full breakdown — every affected drug type, severity by severity
Corn silk also raises your risk of low potassium (hypokalemia) when taken with corticosteroids or diuretics, and it may increase the chance of low blood sugar (hypoglycemia) if you're on diabetes medications. Because corn silk contains vitamin K, it can also interfere with warfarin — you'd need to keep your intake consistent to maintain steady blood thinning.
Uva ursi herb extract has theoretical interactions with several drug-metabolizing pathways: it may affect how your body breaks down medications processed by CYP2C19 or CYP3A4 enzymes, or drugs cleared by glucuronidation. It may also raise lithium levels if you take that medication, and urinary acidifiers can reduce uva ursi's own effects.
Marshmallow leaf extract carries minor interactions — it may impair absorption of oral medications and theoretically has antiplatelet effects, though the leaf (not flower) is less likely to cause issues. Couch grass root extract was checked and shows no known interactions.
Altogether, these interactions span 2,124 individual medications. Check your exact medications with the tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Urinary Bladder Support?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Urinary Bladder Support interact with 2,143 drugs. Click any drug to see the details.
3 of the 4 ingredients in Urinary Bladder Support interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Leaf Extract, Dry Uva Ursi Herb Extract, Dry Corn Silk Extract, Dry
AmitriptylineElavil
How Amitriptyline interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amitriptyline interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amitriptyline, Chlordiazepoxide interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amitriptyline, Perphenazine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amlodipine interactionCorn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Amlodipine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Amlodipine Benzoate interactionUva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amlodipine Benzoate interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Amlodipine Besilate interactionUva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amlodipine Besilate interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amlodipine Besylate interactionCorn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Amlodipine Besylate interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Amlodipine Besylate, Benazepril interactionUva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amlodipine Besylate, Benazepril interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Amlodipine, Celecoxib interactionUva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amlodipine, Celecoxib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Read the full Corn Silk Extract, Dry + Ammonium Chloride interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Ammonium Chloride interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmprenavirAgenerase
How Amprenavir interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract, Dry + Amprenavir interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Amprenavir interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Corn Silk Extract, Dry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionUva Ursi Herb Extract, DryP-glycoprotein Substrates Minor
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract, Dry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionApalutamideErleada
How Apalutamide interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Apalutamide interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Apalutamide interactionApixabanEliquis
How Apixaban interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Apixaban interactionMarshmallow Leaf Extract, DryOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Apixaban interactionApomorphineAPO-go, APO-go Pen, APO-go PFS, Apokyn, Uprima
How Apomorphine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryP-glycoprotein Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract, Dry + Apomorphine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Apomorphine interactionApomorphine HydrochlorideKynmobi
How Apomorphine Hydrochloride interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryGlucuronidated Drugs, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract, Dry + Apomorphine Hydrochloride interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Apomorphine Hydrochloride interactionApremilastOtezla
How Apremilast interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Apremilast interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Apremilast interactionAprepitantCinvanti, Emend
How Aprepitant interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aprepitant interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Aprepitant interactionAprocitentanTryvio
How Aprocitentan interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Aprocitentan interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Aprocitentan interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aripiprazole interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aripiprazole Lauroxil interactionArmodafinilNuvigil
How Armodafinil interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Armodafinil interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Armodafinil interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Butalbital, Caffeine interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionMarshmallow Leaf Extract, DryOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Butalbital, Caffeine, Phenacetin interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Caffeine interactionMarshmallow Leaf Extract, DryOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Caffeine, Codeine Phosphate interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionMarshmallow Leaf Extract, DryOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract, Dry + Aspirin, Caffeine, Dover's Pwd interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Aspirin, Caffeine, Dover's Pwd interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Urinary Bladder Support with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Marshmallow Leaf Extract, Dry
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
Uva Ursi Herb Extract, Dry
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Corn Silk Extract, Dry
Antidiabetes Drugs
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.
Antihypertensive Drugs
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.
Corticosteroids
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.
Diuretic Drugs
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.
Warfarin (Coumadin)
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.
Brand information
Manufacturer and brand details for Urinary Bladder Support, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- Street Address
- 510 Sumner St. Ste. 613
- City
- Honolulu
- State
- HI
- ZipCode
- 96817
- Phone Number
- 888-854-2924
- Web Address
- www.hawaiipharm.com
Urinary Bladder Support by Hawaii Pharm: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Urinary Bladder Support’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Marshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph → Herb & supplement monographCorn Silk
Interacts with 290 drugsCorn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...
Read the full Corn Silk monograph → Herb & supplement monographCouch Grass
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...
Read the full Couch Grass monograph → Herb & supplement monographUva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph →Sources & How We Checked
Urinary Bladder Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Marshmallow 5 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.
Corn Silk 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
- Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed
Uva Ursi 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
- Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
- Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
- Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC