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Dietary supplement

Vigor Blue Ingredients & Drug Interactions

by Vigor Labs

Vigor Blue label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vigor Blue against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Vigor Blue is a dietary supplement by Vigor Labs with 2 active ingredients. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Propionyl-L-Carnitine Hydrochloride, Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vigor Blue by Vigor Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with Vigor Blue by Vigor Labs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vigor Blue by Vigor Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Vigor Blue contains 2 active ingredients: glycine and propionyl-L-carnitine hydrochloride. The product also contains inactive ingredients—gelatin, silicon dioxide, and magnesium stearate—which are used to form and stabilize the capsule.

Glycine is an amino acid. Propionyl-L-carnitine hydrochloride is a compound derived from carnitine, which plays a role in how your cells produce energy.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Companion supplement for erectile dysfunction treatment.
  • We looked for evidence on: Erectile dysfunction (ED), Age-related testosterone deficiency, Peyronie disease, Sexual function, Penile hemodynamics.
  • The closest evidence on file: Propionyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED) (Natural Medicines).
  • Also on file: Propionyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Peyronie disease, Age-related testosterone deficiency.

Glycine is possibly effective for schizophrenia, though the evidence is limited. For 3-phosphoglycerate dehydrogenase deficiency, ADHD, benign prostatic hyperplasia, and cystic fibrosis, there isn't enough reliable evidence to say whether it works.

Propionyl-L-carnitine is possibly effective for ulcerative colitis, heart failure, and angina. Evidence for cardiovascular disease more broadly is also possibly effective, but again limited.

The evidence, ingredient by ingredient Glycine Propionyl-l-carnitine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. Rare side effects include mild sedation, irritability, insomnia, fatigue, memory impairment, headache, and sensory impairment—though it's unclear if glycine is the cause.

Soft stools, nausea, vomiting, and upper GI discomfort have also been reported rarely and resolve quickly if you stop taking it. There isn't enough reliable safety data for pregnancy, so it's best avoided unless your doctor approves.

Breastfeeding safety data are also insufficient; caution is advised. Propionyl-L-carnitine is generally well tolerated for short-term use.

Common side effects are diarrhea, stomach pain, nausea, vomiting, and a fishy odor of urine, breath, or sweat. Bronchitis and back pain were reported more often in one clinical trial than with placebo.

It is not safe in pregnancy and should be avoided while breastfeeding.

Side effects, ingredient by ingredient Glycine Propionyl-l-carnitine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Propionyl-l-carnitine, Glycine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 20 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Vigor Blue, check with your pharmacist if you take clozapine (Clozaril) for schizophrenia, or blood thinners like warfarin (Coumadin) or acenocoumarol (Sintrom), or thyroid hormone replacement. All of these are Moderate interactions with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have schizophrenia and take clozapine, or if you take blood thinners or thyroid hormone, talk to your pharmacist before starting this product. Glycine and propionyl-L-carnitine show some promise for specific heart and digestive conditions, but evidence is limited for many uses.

Your pharmacist can help you weigh whether this is right for you and check your exact medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vigor Blue, straight from the product label.

Brand Vigor Labs
Barcode (UPC) 860006695514
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334347
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vigor Blue by Vigor Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
860006695514
IngredientAmount% DV
Glycine100 mg--
Propionyl-L-Carnitine Hydrochloride2000 mg--

Other ingredients: Gelatin, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Companion supplement for: Viagra HIMS Blue Chew

Suggested use: As a dietary supplement, take three (3) capsules daily, or 30 minutes to 4 hours before intercourse, in combination with prescribed sildnafil (PDE5 inhibitor), or as directed by your health care professional.

FDA Statement of Identity

Dietary Supplement

General Statements

Limited edition

Follow us Instagram @VigorLabs X @VigorLabs Facebook @VigorLabs

Precautions

Caution: Do not exceed recommended dose. Discontinue use immediately if nausea, sleeplessness, or nervousness occur. If you have questions about the advisability of taking this product, consult your physician prior to use. Do not use this product if printed inner seal under cap is missing or broken.

This product is not intended for pregnant or nursing mothers, children under the age of 18. Do not take this product if you have a known medical condition including high blood pressure, diabetes, any cardiovascular disorder, heart disease, hyperthyroidism, or are taking anti-depressant or contra-indicated medications.

This product is not intended for pregnant or nursing mothers, children under the age of 18. Keep out of reach of children Must be 18 years of age to use or buy

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

USA Made in the USA

Formulation

Natural PDE5 inhibitor companion

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vigor Blue by Vigor Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vigor Blue label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vigor Blue by Vigor Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glycine

Interacts with
1 drug
100 mg per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions

Propionyl-L-Carnitine Hydrochloride

Interacts with
19 drugs
2000 mg per serving

Propionyl-l-carnitine is a form of the amino acid derivative carnitine that the body uses to help turn fat into energy, and it is studied mostly for c...

Propionyl-L-Carnitine Hydrochloride monograph & interactions

Other (inactive) ingredients: Gelatin, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vigor Blue by Vigor Labs Drug Interactions

Want to check YOUR meds against Vigor Blue?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
20Drugs
20 Moderate

Ingredients driving the most interactions

Propionyl-L-Carnitine Hydrochloride 19
Glycine 1

Individual Drug Interactions

The ingredients in Vigor Blue interact with 20 drugs. Click any drug to see the details.

2 of the 2 ingredients in Vigor Blue interact with drugs. Each result below shows which ingredient is responsible. Propionyl-L-Carnitine Hydrochloride Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Vigor Blue with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Propionyl-L-Carnitine Hydrochloride3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, propionyl-L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine, the parent compound of propionyl-L-carnitine, might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation when L-carnitine was taken with acenocoumarol. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product. It is unclear if such an interaction would also occur with propionyl-L-carnitine.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, acetyl-L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism. It is unclear if such an interaction would occur with propionyl-L-carnitine.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Theoretically, propionyl-L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine, the parent compound of propionyl-L-carnitine, might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with propionyl-L-carnitine and warfarin.

Likelihood Possible Evidence D
Propionyl-L-Carnitine Hydrochloride full monograph & interactions

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vigor Blue, from the product label.

Vigor Labs

See all Vigor Labs products
Name
Bioearth, LLC
Street Address
1430 S. Dixie Hwy. Suite 105-1074
City
Coral Gables
State
FL
ZipCode
33146
Phone Number
(888) 698-6603
Web Address
www.vigorlabs.com
Pharmacist Counseling Corner

Vigor Blue by Vigor Labs: Common Questions

Does Vigor Blue by Vigor Labs interact with any medications?
Yes. Based on its ingredients, Vigor Blue has a known interaction with 20 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vigor Blue contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Vigor Blue if I'm pregnant or breastfeeding?
Not based on what we know. Propionyl-L-carnitine is not safe in pregnancy and should be avoided while breastfeeding. Glycine hasn't been studied enough in pregnancy or while breastfeeding—there isn't enough data to know either way. Talk with your doctor or pharmacist for personalized advice.
What is propionyl-L-carnitine hydrochloride, and what's it supposed to do?
It's a form of carnitine, a compound that helps your cells make energy. In this product it's included for its possibly effective uses in heart failure, angina, and some digestive conditions, though the evidence is limited.
Does glycine help with schizophrenia?
There's some evidence it may help—it's rated possibly effective for schizophrenia. But if you already take clozapine for schizophrenia, adding glycine may actually make symptoms worse, so don't use this product without talking to your doctor first.
What side effects might I get from this product?
Glycine can rarely cause mild sedation, irritability, insomnia, fatigue, headache, or GI upset that usually clears up if you stop. Propionyl-L-carnitine more commonly causes diarrhea, nausea, stomach pain, or a fishy odor to urine, breath, and sweat.
Is this product safe to use long-term?
Glycine is generally well tolerated, but long-term safety data are limited. Propionyl-L-carnitine is well tolerated for short-term use, but talk to your healthcare provider first about extended use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vigor Blue label
Go deeper

The Full Monographs Behind Vigor Blue’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph → Herb & supplement monograph

Propionyl-l-carnitine

Interacts with 19 drugs

Propionyl-l-carnitine is a form of the amino acid derivative carnitine that the body uses to help turn fat into energy, and it is studied mostly for circulation problems like peripheral arte...

Read the full Propionyl-l-carnitine monograph →
Sources

Sources & How We Checked

Vigor Blue's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Propionyl-l-carnitine 12 references
  1. Cherchi A, Lai C, Onnis E, et al. Propionyl carnitine in stable effort angina. Cardiovasc Drugs Ther 1990;4:481-6. PubMed
  2. Bartels GL, Remme WJ, den Hartog FR, et al. Additional anti-ischemic effects of long-term L-propionylcarnitine in anginal patients treated with conventional antianginal therapy. Cardiovasc Drugs Ther 1995;9:749-53.
  3. Caponnetto S, Canale C, Masperone MA, et al. Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction. Eur Heart J 1994;15:1267-73. PubMed
  4. Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
  5. Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
  6. Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
  7. Gentile V, Vicini P, Prigiotti G, et al. Preliminary observations on the use of propionyl-L-carnitine in combination with sildenafil in patients with erectile dysfunction and diabetes. Curr Med Res Opin 2004;20:1377-84. PubMed
  8. 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
  9. Brass EP, Koster D, Hiatt WR, Amato A. A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication. Vasc Med 2013;18:3-12.
  10. Hiatt WR, Creager MA, Amato A, Brass EP. Effect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease. J Cardiopulm Rehabil Prev 2011;31:125-32. PubMed
  11. Jacobs PL, Goldstein ER, Blackburn W, et al. Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males. J Int Soc Sports Nutr 2009;6:9. PubMed
  12. Jacobs PL, Goldstein ER. Long-term glycine propionyl-l-carnitine supplementation and paradoxical effects on repeated anaerobic sprint performance. J Int Soc Sports Nutr 2010;7:35.

See these in context on the Propionyl-l-carnitine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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