Vitamin D Gummies Fruit Flavor Ingredients & Drug Interactions
by VitaDrops
What is this page for?
First and foremost: checking Vitamin D Gummies Fruit Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vitamin D Gummies Fruit Flavor is a dietary supplement by VitaDrops with 2 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 715 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vitamin D Gummies Fruit Flavor by VitaDrops
Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin D Gummies Fruit Flavor by VitaDrops — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Vitamin D Gummies Fruit Flavor by VitaDrops
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
VitaDrops Vitamin D Gummies contain one active ingredient: vitamin D. The gummies also contain inactive ingredients — glucose syrup, water, pectin, sodium citrate, citric acid, natural flavors, and natural color — that give them their texture, taste, and shelf life.
Does it work?
Strong evidence
Vitamin D in these gummies is effective for treating rickets, osteomalacia (soft bones from vitamin D deficiency), renal bone disease, hypoparathyroidism (low parathyroid hormone), and familial hypophosphatemia (a rare inherited disorder of phosphate metabolism). If you're taking these for a diagnosed deficiency or one of these conditions, the evidence supports their use.
How safe is it?
Well-documented data
Vitamin D is generally well tolerated at recommended doses. However, very high doses over time can cause toxicity with symptoms like high blood calcium (hypercalcemia), weak bones in adults, poor growth in children, eye inflammation, and sensitivity to light.
The product facts note that vitamin D is often used during pregnancy at recommended amounts, but only under your doctor's guidance — the same goes for breastfeeding and any amount above recommended doses. If you're pregnant, nursing, or considering higher amounts, talk with your doctor first.
Meds to double-check
Moderate interaction found
Before you start these gummies, double-check with your pharmacist if you take digoxin or other heart rhythm drugs, thiazide diuretics (water pills for blood pressure), verapamil or diltiazem (calcium channel blockers for arrhythmia or high blood pressure), atorvastatin (Lipitor) for cholesterol, calcipotriene (a vitamin D cream for psoriasis), or aluminum-containing products — especially if you have kidney disease. No interactions are documented for ingredients we could not check, but we've flagged all the data we do hold.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
These gummies are a straightforward way to get vitamin D if you have a deficiency or a condition that needs it. If you take heart rhythm medications, blood pressure pills, cholesterol drugs, or water pills, or if you use a vitamin D-based psoriasis cream, check with your pharmacist first — especially if your doses are high.
Keep amounts at or below the recommended daily limit to stay safe.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vitamin D Gummies Fruit Flavor, straight from the product label.
| Brand | VitaDrops |
|---|---|
| Barcode (UPC) | 035046112295 |
| Net contents | 60 Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2024 |
| DSLD ID | 314752 |
| Product type | Vitamin |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vitamin D Gummies Fruit Flavor by VitaDrops, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s) | 2% |
| Sugar | 3 Gram(s) | -- |
| Vitamin D | 50 mcg | 250% |
| Added Sugars | 3 Gram(s) | 6% |
Other ingredients: Glucose Syrup, Water, Pectin, Sodium Citrate, Citric Acid, Natural Flavors, Natural color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 1 serving (2 gummies) daily with food or as directed by your healthcare professional.
Precautions
Keep out of reach of children.
Do not ingest if seal is broken.
Storage
Store in a cool, dry place. Protect from heat, light and moisture.
General Statements
For more information, visit us at www.windmillvitamins.com
Please recycle
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Strong bones & immunity
Pectin based
Gluten free Gelatin free
No milk, eggs, peanuts or soy.
FDA Statement of Identity
Dietary Supplement
Formula
H (Halal)
Seals/Symbols
H (Halal)
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vitamin D Gummies Fruit Flavor by VitaDrops label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vitamin D Gummies Fruit Flavor by VitaDrops
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
Vitamin D
Interacts with715 drugs
Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...
Vitamin D monograph & interactionsOther (inactive) ingredients: Glucose Syrup, Water, Pectin, Sodium Citrate, Citric Acid, Natural Flavors, Natural color. These complete the product’s ingredient list but are not active constituents.
Vitamin D Gummies Fruit Flavor by VitaDrops Drug Interactions
HelloPharmacist Interaction Report
VitaDrops Vitamin D Gummies do interact with several medications, and the most serious concern involves heart rhythm drugs.
High-dose vitamin D can raise your blood calcium level (hypercalcemia), which increases the risk of dangerous irregular heartbeats if you're taking digoxin (a heart medication). The same high-dose risk applies to verapamil and diltiazem, which are used for arrhythmia and high blood pressure — elevated calcium can make them less effective.
Read the full breakdown — every affected drug type, severity by severity
Thiazide water pills (diuretics) are another Moderate concern: they already lower how much calcium your body loses in urine, and vitamin D amplifies that effect, raising your calcium level further. Calcipotriene, a vitamin D-like psoriasis cream, can also push calcium too high when combined with these gummies.
A small study suggests vitamin D might reduce how well atorvastatin (Lipitor) works for cholesterol, and there's a theoretical risk that vitamin D could interfere with enzymes that break down many other medications — though this is listed as Minor.
One more Moderate finding: vitamin D may increase absorption of aluminum, though this risk has mainly been seen in people with kidney failure. Altogether, these interactions span 705 individual medications.
The dose matters a lot — most of these risks are tied to vitamin D amounts above 4000 IU daily for adults. Check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Vitamin D Gummies Fruit Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vitamin D Gummies Fruit Flavor interact with 715 drugs. Click any drug to see the details.
1 of the 2 ingredients in Vitamin D Gummies Fruit Flavor interact with drugs. Each result below shows which ingredient is responsible. Vitamin D
Chlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Chlorthalidone, Clonidine interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Cyclothiazide interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Deserpidine, Methyclothiazide interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
Read the full Vitamin D + Digoxin interactionDihydroxyaluminum Sodium CarbonateRolaids
How Dihydroxyaluminum Sodium Carbonate interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Dihydroxyaluminum Sodium Carbonate interactionDiltiazemAdizem-SR, Adizem-XL, Angitil SR, Angitil XL, Calcicard CR, Cardizem +23 more
How Diltiazem interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DDiltiazem (cardizem, Others), Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
Read the full Vitamin D + Diltiazem interactionDiltiazem, EnalaprilTeczem
How Diltiazem, Enalapril interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DCytochrome P450 3a4 (cyp3a4) Substrates, Diltiazem (cardizem, Others) Moderate
Interaction Summary
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
Read the full Vitamin D + Diltiazem, Enalapril interactionEnalapril Maleate, HydrochlorothiazideVaseretic
How Enalapril Maleate, Hydrochlorothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Enalapril Maleate, Hydrochlorothiazide interactionEzetimibe, AtorvastatinLiptruzet
How Ezetimibe, Atorvastatin interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAtorvastatin (lipitor), Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Vitamin D might reduce absorption of atorvastatin.
Read the full Vitamin D + Ezetimibe, Atorvastatin interactionFish Oil TriglyceridesOmegaven
How Fish Oil Triglycerides interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DAluminum Moderate
Interaction Summary
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
Read the full Vitamin D + Fish Oil Triglycerides interactionFosinopril, HydrochlorothiazideMonopril HCT
How Fosinopril, Hydrochlorothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Fosinopril, Hydrochlorothiazide interactionGuanethidine, HydrochlorothiazideEsimil
How Guanethidine, Hydrochlorothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Guanethidine, Hydrochlorothiazide interactionHydralazine, HydrochlorothiazideApresazide, Apresoline-Esidrix
How Hydralazine, Hydrochlorothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydralazine, Hydrochlorothiazide interactionHydralazine, Hydrochlorothiazide, ReserpineSer-Ap-Es, Unipres, Uniserp
How Hydralazine, Hydrochlorothiazide, Reserpine interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydralazine, Hydrochlorothiazide, Reserpine interactionHydrochlorothiazideAquazide, Aquazide H, Esidrix, HCTZ, Hydro, Hydro-D +3 more
How Hydrochlorothiazide interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide interactionHydrochlorothiazide, IrbesartanAvalide
How Hydrochlorothiazide, Irbesartan interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Irbesartan interactionHydrochlorothiazide, LabetalolTrandate HCT
How Hydrochlorothiazide, Labetalol interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Labetalol interactionHydrochlorothiazide, LisinoprilPrinzide, Zestoretic
How Hydrochlorothiazide, Lisinopril interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Lisinopril interactionHydrochlorothiazide, Losartan PotassiumHyzaar
How Hydrochlorothiazide, Losartan Potassium interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Losartan Potassium interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Methyldopa interactionHydrochlorothiazide, MetoprololLopressor HCT
How Hydrochlorothiazide, Metoprolol interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Metoprolol interactionHydrochlorothiazide, MoexiprilUniretic
How Hydrochlorothiazide, Moexipril interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Moexipril interactionHydrochlorothiazide, PindololViskazide
How Hydrochlorothiazide, Pindolol interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Pindolol interactionHydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Propranolol interactionHydrochlorothiazide, QuinaprilAccuretic
How Hydrochlorothiazide, Quinapril interacts with Vitamin D Gummies Fruit Flavor — through 1 ingredient. Tap an ingredient for the detail:
Vitamin DThiazide Diuretics Moderate
Interaction Summary
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Read the full Vitamin D + Hydrochlorothiazide, Quinapril interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vitamin D Gummies Fruit Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin D
Aluminum
Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.
Atorvastatin (Lipitor)
Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.
Calcipotriene (Dovonex)
Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.
Digoxin (Lanoxin)
Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.
Diltiazem (Cardizem, Others)
Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.
Thiazide Diuretics
Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.
Verapamil (Calan, Others)
Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.
Brand information
Manufacturer and brand details for Vitamin D Gummies Fruit Flavor, from the product label.
VitaDrops
See all VitaDrops products- Name
- Windmill Health Products
- Street Address
- 10 Henderson Drive
- City
- West Caldwell
- State
- NJ
- ZipCode
- 07006
- Web Address
- www.windmillvitamins.com
Vitamin D Gummies Fruit Flavor by VitaDrops: Common Questions
Does Vitamin D Gummies Fruit Flavor by VitaDrops interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take these gummies while pregnant or breastfeeding?
Can too much vitamin D from these gummies hurt me?
What is vitamin D actually used for?
Do these gummies have any fillers?
If I take these gummies, will they affect how my cholesterol or heart medications work?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Vitamin D Gummies Fruit Flavor is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Vitamin D Gummies Fruit Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Vitamin D Gummies Fruit Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin D 26 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
- Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
- Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
- Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
- Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
- Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
- Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
- Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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