Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Vitamin D3 Formula Ingredients & Drug Interactions

by Beyond Health

Vitamin D3 Formula label
See full label image
Capsule Category: Vitamin
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin D3 Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin D3 Formula is a dietary supplement by Beyond Health with 5 active ingredients. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 1,048 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are D-Alpha Tocopherol, Vitamin D3, Vitamin A. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Vitamin D3 Formula by Beyond Health

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin D3 Formula by Beyond Health — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Vitamin D3 Formula by Beyond Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Vitamin D3 Formula contains five active ingredients. Vitamin K2 supports blood clotting and bone health.

Vitamin D3 is the active form your body makes from sunlight; it helps your body absorb calcium and supports immune function. D-Alpha Tocopherol is a natural form of vitamin E that acts as an antioxidant.

Vitamin A supports vision and immune health. Mixed Tocotrienols are compounds related to vitamin E that may have antioxidant properties.

The product also contains inactive ingredients including gelatin, glycerin, beeswax, purified water, sunflower lecithin, rice bran oil, and turmeric powder.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Vitamin D, E, A, and K supplementation.
  • We looked for evidence on: Aging, Aging skin, Atopic dermatitis (eczema), Acne, Age-related macular degeneration (AMD), Ataxia with vitamin E deficiency (AVED) — and 4 related terms.
  • The strongest evidence on file: Vitamin E is rated "Effective" for Vitamin E deficiency (Natural Medicines).
  • Also on file: Vitamin E is rated "Effective" for Ataxia with vitamin E deficiency (AVED).
  • Also on file: Vitamin A is rated "Possibly Effective" for Aging skin.

The evidence varies by ingredient and condition. Vitamin D3 is effective for rickets, osteomalacia, renal bone disease, and familial hypophosphatemia — these are established uses.

Vitamin K2 is effective for vitamin K deficiency states and clotting disorders. Vitamin E (D-Alpha Tocopherol) is effective for vitamin E deficiency itself, though it's possibly effective for conditions like Alzheimer's disease and beta-thalassemia.

Vitamin A is effective for vitamin A deficiency and possibly effective for measles and aging skin. Mixed Tocotrienols show possibly effective evidence only for diabetes; evidence for other uses like cholesterol is insufficient or suggests they may not help.

The product isn't positioned as treatment for a single condition, so talk with your pharmacist or doctor about whether the combination matches what you need.

The evidence, ingredient by ingredient Vitamin K Vitamin D Vitamin E Vitamin A Tocotrienols

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D3 is generally well tolerated at recommended doses; very high doses over time can cause vitamin D toxicity with symptoms like elevated calcium, bone loss, and decreased growth in children. Vitamin K2 taken orally is generally well tolerated, though some people report mild stomach upset, nausea, or diarrhea.

Vitamin E may increase bleeding risk, especially at high doses or with certain medications, and there's a rare concern about hemorrhagic stroke with long-term high-dose synthetic vitamin E in male smokers. Vitamin A is generally safe at recommended amounts, but high doses can accumulate in your body and cause toxicity including liver damage, headache, and skin problems.

Mixed Tocotrienols appear well tolerated in studies, though long-term safety at supplement doses isn't fully established. The safety data on Vitamin D3 during pregnancy and lactation is not on file in our data; talk with your doctor about use during these times.

Side effects, ingredient by ingredient Vitamin K Vitamin D Vitamin E Vitamin A Tocotrienols

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Vitamin D, Vitamin E, Vitamin A, Vitamin K, Tocotrienols.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; heart-rhythm medications.
  • For scale: 1,049 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take warfarin (a blood thinner) — Vitamin K2 can reduce its effect, and Vitamin A and E may increase bleeding risk. Thiazide diuretics, verapamil, diltiazem, digoxin, atorvastatin, or calcipotriene need caution with the vitamin D3 dose.

Retinoid medications (like isotretinoin) are a Major concern with the Vitamin A in this product. Tetracycline antibiotics and any other blood thinners or antiplatelet agents should be flagged.

Use the medication search tool on this page with your full list before you begin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is a multivitamin formula with several active ingredients, each with established or possible benefits. It's not right for anyone taking warfarin, retinoid medications, or certain other prescription drugs without checking first.

Even if you don't take those, run your exact medications through the checker below before you start — the ingredient count and interaction potential are substantial. Talk with your pharmacist about whether the combination of these vitamins suits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin D3 Formula, straight from the product label.

Brand Beyond Health
Barcode (UPC) 610079876491
Net contents 150 Gel Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 306904
Product type Vitamin
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin D3 Formula by Beyond Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gel Capsule(s)
Maximum serving Sizes:
1 Gel Capsule(s)
Servings per container
150
UPC/BARCODE
610079876491
IngredientAmount% DV
Vitamin K210 mg8.3%
Vitamin D3125 mcg625%
D-Alpha Tocopherol0.67 mg4.5%
Vitamin A300 mcg33%
Mixed Tocotrienols1.2 mg--

Other ingredients: Gelatin, Glycerin, Yellow Beeswax, Water, Purified, Sunflower Lecithin, Rice Bran Oil, Turmeric, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Beyond Health Helping You Get Well and Stay Well

One Disease Two Causes Six Pathways

Formula

Vitamin D3 Formula

FDA Statement of Identity

Dietary Supplements

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 softgel capsule daily with food, or as directed by a health care professional.

FDA Disclaimer Statement

This product has not been evaluated by the Food and Drug Administration and is not intended to diagnose, cure, or prevent any disease.

Storage

Store in a cool, dry place.

Must be stored with cap on tightly. Do not use if the tamper-resistant band around the cap or inner seal below the cap appears to have been tampered with or is missing.

General Statements

World Class Supplements

Precautions

Keep out of reach of children.

Formulation

Does not contain: wheat, rye, oats, corn, barley, gluten, egg, dairy, sugar, GMOs, shellfish, yeast, preservatives, artificial colorings, soy, or artificial flavorings.

Manufactured in the U.S.A.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin D3 Formula by Beyond Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin D3 Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin D3 Formula by Beyond Health

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gel Capsule(s) Dosage formCapsule Servings per container150 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin K2

Interacts with
2 drugs
10 mg per serving Form: Menaquinone-7

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K2 monograph & interactions

Vitamin D3

Interacts with
715 drugs
125 mcg per serving Form: Fish Liver Oil

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D3 monograph & interactions

D-Alpha Tocopherol

Interacts with
764 drugs
0.67 mg per serving Form: Oryza Rice Bran Oil

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correc...

D-Alpha Tocopherol monograph & interactions

Vitamin A

Interacts with
387 drugs
300 mcg per serving Form: Fish Liver Oil

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Mixed Tocotrienols

Interacts with
122 drugs
1.2 mg per serving Form: Rice bran oil

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early resea...

Mixed Tocotrienols monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Yellow Beeswax, Water, Purified, Sunflower Lecithin, Rice Bran Oil, Turmeric, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin D3 Formula by Beyond Health Drug Interactions

Want to check YOUR meds against Vitamin D3 Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,048Drugs
11 Major 1,037 Moderate

Ingredients driving the most interactions

D-Alpha Tocopherol 764
Vitamin D3 715
Vitamin A 387
Mixed Tocotrienols 122
Vitamin K2 2

Individual Drug Interactions

The ingredients in Vitamin D3 Formula interact with 1,048 drugs. Click any drug to see the details.

5 of the 5 ingredients in Vitamin D3 Formula interact with drugs. Each result below shows which ingredient is responsible. D-Alpha Tocopherol Vitamin D3 Vitamin A Mixed Tocotrienols Vitamin K2

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin D3 Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

D-Alpha Tocopherol8 drug types · 764 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of alkylating agents.
There's concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Concomitant use of vitamin E and anticoagulant or antiplatelet agents might increase the risk of bleeding.
Vitamin E seems to inhibit of platelet aggregation and antagonize the effects of vitamin K-dependent clotting factors. These effects appear to be dose-dependent, and are probably only likely to be clinically significant with doses of at least 800 units daily. Mixed tocopherols, such as those found in food, might have a greater antiplatelet effect than alpha-tocopherol. RRR alpha-tocopherol (natural vitamin E) 1000 IU daily antagonizes vitamin K-dependent clotting factors. Advise patients to avoid high doses of vitamin E, especially in people with low vitamin K intake or other risk factors for bleeding.

Likelihood Possible Evidence B
Antitumor Antibiotics

Theoretically, antioxidant effects of vitamin E might reduce the effectiveness of antitumor antibiotics.
There's concern that antioxidants could reduce the activity of antitumor antibiotic drugs such as doxorubicin, which generate free radicals. However, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that might interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin E have on chemotherapy involving antitumor antibiotics. Advise patients to consult their oncologist before using vitamin E supplements, especially in high doses.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

A specific form of vitamin E might increase absorption and levels of cyclosporine.
There is some evidence that one specific formulation of vitamin E (D-alpha-tocopheryl-polyethylene glycol-1000 succinate, TPGS, tocophersolan, Liqui-E) might increase absorption of cyclosporine. This vitamin E formulation forms micelles which seems to increase absorption of cyclosporine by 40% to 72% in some patients. However, this interaction is unlikely to occur with the usual forms of vitamin E.

Likelihood Unlikely Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.
Vitamin E appears to bind with the nuclear receptor, pregnane X receptor (PXR), which results in increased expression of CYP3A4. Although the clinical significance of this is not known, use caution when considering concomitant use of vitamin E and other drugs affected by these enzymes.

Likelihood Possible Evidence D
Selumetinib (Koselugo)

Taking selumetinib with vitamin E can result in a total daily dose of vitamin E that exceeds safe limits and therefore might increase the risk of bleeding.
Selumetinib contains 48-54 IU vitamin E per capsule. The increased risk of bleeding with vitamin E appears to be dose-dependent. Be cautious when using selumetinib in combination with supplemental vitamin E, especially in patients at higher risk of bleed, such as those with chronic conditions and those taking antiplatelet drugs.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Using vitamin E with warfarin might increase the risk of bleeding.
Due to interference with production of vitamin K-dependent clotting factors, use of more than 400 IU of vitamin E daily with warfarin might increase prothrombin time (PT), INR, and the risk of bleeding,. At a dose of 1000 IU per day, vitamin E can antagonize vitamin K-dependent clotting factors even in people not taking warfarin. Limited clinical evidence suggests that doses up to 1200 IU daily may be used safely by patients taking warfarin, but this may not be applicable in all patient populations.

Likelihood Possible Evidence B
Niacin

Vitamin E might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises high-density lipoprotein (HDL) cholesterol levels in people with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50%. Vitamin E alone combined with a statin does not seem to decrease HDL levels. It is not known whether the adverse effect on HDL is due to one of the other antioxidants or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
D-Alpha Tocopherol full monograph & interactions

Vitamin D38 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D3 full monograph & interactions

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A full monograph & interactions

Mixed Tocotrienols1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
Mixed Tocotrienols full monograph & interactions

Vitamin K21 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
Vitamin K2 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin D3 Formula, from the product label.

Beyond Health

See all Beyond Health products
Name
Beyond Health International
Street Address
6555 Powerline Road, #101
City
Fort Lauderdale
State
FL
ZipCode
33309
Phone Number
800-250-3063
Web Address
www.beyondhealth.com
Pharmacist Counseling Corner

Vitamin D3 Formula by Beyond Health: Common Questions

Does Vitamin D3 Formula by Beyond Health interact with any medications?
Yes. Based on its ingredients, Vitamin D3 Formula has a known interaction with 1,048 medications, including 11 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin D3 Formula contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on warfarin?
Not without checking with your pharmacist or doctor first. Both Vitamin K2 and Vitamin A in this product can interfere with warfarin's blood-thinning effect or increase bleeding risk — the Vitamin K2 effect is especially strong. You'll need personalized advice.
What are the most common side effects?
Vitamin K2 and Vitamin E may cause mild stomach upset, nausea, or diarrhea in some people. At recommended doses, side effects are generally uncommon. High doses of Vitamin A can cause headache, dry skin, and fatigue over time.
Is this safe during pregnancy?
Vitamin K2 is likely safe in pregnancy. High-dose Vitamin A (especially as retinol) can cause birth defects and should be avoided. The safety data for Vitamin D3 during pregnancy isn't on file in our system — ask your doctor or pharmacist for guidance on this product during pregnancy.
Can this help with bone health?
Vitamin D3 is effective for rickets and renal bone disease. Vitamin K2 is possibly effective for osteoporosis. The combination may support bone health, but talk with your doctor about whether this product and its doses are right for your situation.
Should I worry about vitamin A toxicity from this product?
At recommended supplement doses, Vitamin A is generally safe. High doses over time can accumulate and cause toxicity with symptoms like liver damage, headache, and skin problems. Don't exceed the tolerable upper intake level without medical supervision.
Does Vitamin E in this increase bleeding risk?
At typical supplement doses, Vitamin E is generally well tolerated. High doses — and especially combined with blood thinners or antiplatelet drugs — may increase bleeding risk. If you take those medications, check with your pharmacist before adding this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin D3 Formula label
Go deeper

The Full Monographs Behind Vitamin D3 Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin K

Interacts with 2 drugs

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but supplements are sometimes used for deficiency...

Read the full Vitamin K monograph → Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

Vitamin E

Interacts with 764 drugs

Vitamin E is an essential fat-soluble vitamin and antioxidant that most people get in adequate amounts from a normal diet. Supplements can help correct a true deficiency, but high-dose vitam...

Read the full Vitamin E monograph → Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph →
Sources

Sources & How We Checked

Vitamin D3 Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 136 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
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Vitamin D 26 references
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Vitamin E 64 references
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Vitamin A 31 references
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  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
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Tocotrienols 4 references
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  3. Khoo TL, Halim AS, Zakaria Z, Mat Saad AZ, Wu LY, Lau HY. A prospective, randomised, double-blinded trial to study the efficacy of topical tocotrienol in the prevention of hypertrophic scars. J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):e137-45. Epub 201 PubMed
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