Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Wormwood Ingredients & Drug Interactions

by Herb Pharm

Wormwood label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wormwood against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wormwood is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, intestinal parasites, crohn's disease symptoms.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wormwood Flowering Aerial Parts Extract, Fresh, Undried. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Wormwood by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Wormwood by Herb Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Wormwood by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Wormwood Flowering Aerial Parts Extract, made from fresh, undried plant material. Wormwood is an herbal extract that's been used traditionally for digestive and biliary concerns.

The liquid is suspended in cane alcohol as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Wormwood's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: gastrointestinal system restoration and digestive support.
  • We looked for evidence on: Dyspepsia, Gastritis, Crohn disease, indigestion, poor appetite, digestive upset — and 1 related terms.
  • The closest evidence on file: Wormwood is rated "Insufficient Reliable Evidence To Rate" for Crohn disease (Natural Medicines).
  • Also on file: Wormwood is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia, Gastritis.

The evidence behind wormwood for its traditional uses — biliary disorders, Crohn disease, depression, indigestion (dyspepsia), and osteoarthritis — is insufficient. We don't hold reliable evidence that it works for any of these conditions.

If you're considering it for a specific health concern, talk with your pharmacist or doctor about whether the evidence supports its use for you.

The evidence, ingredient by ingredient Wormwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wormwood contains thujone, a compound that can be toxic at higher doses. Short-term use of properly prepared products may be acceptable, but chronic or high-dose use carries real risks.

Common side effects from the oil include nausea, vomiting, and muscle aches. Rare but serious effects — acute kidney toxicity, severe muscle breakdown (rhabdomyolysis), and seizures — have been reported.

Chronic heavy use has historically been linked to hallucinations, tremors, paralysis, and brain damage. Wormwood is unsafe during pregnancy because it may stimulate the uterus.

There isn't enough safety data to recommend it while breastfeeding, so it's best avoided then too.

Side effects, ingredient by ingredient Wormwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsants (seizure medications), you need to check your specific drug before using this product — wormwood may interfere with how it works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Wormwood is a single-ingredient herbal extract with a major interaction concern for anyone on seizure medications. If you take anticonvulsants, check with your pharmacist first.

Even without drug interactions, the thujone it contains carries toxicity risks at higher doses, and the evidence for its intended uses is weak. This isn't a product to use long-term or casually.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wormwood, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700002503
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 307833
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wormwood by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.45 mL
Maximum serving Sizes:
0.45 mL
Servings per container
264
UPC/BARCODE
090700002503
IngredientAmount% DV
Wormwood Flowering Aerial Parts Extract, Fresh, Undried395 mg--

Other ingredients: Cane Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Shake well before using Adults: Add 0.45 ml (20 drops) to 2 oz. of water or juice, 1 to 3 times per day. Best taken between meals.

Precautions

Caution: Not for use in pregnancy or nursing.

Not for long term use, do not exceed recommended serving.

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Artemisia absinthium

Wormwood liquid extract

We prepare our Wormwood extract from the fresh (undried) flowering aerial parts of certified organic Artemisia absinthium plants.

Formulation

System restoration Gastrointestinal

Gluten-free

Certified organic by Organic Certifiers

Seals/Symbols

USDA Organic

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wormwood by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wormwood label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wormwood by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.45 mL Dosage formLiquid Servings per container264 Amounts shown are per serving.

Wormwood Flowering Aerial Parts Extract, Fresh, Undried

Interacts with
50 drugs
395 mg per serving Form: Artemisia absinthium Flowering Aerial Parts Extract, Fresh, Undried

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It...

Wormwood Flowering Aerial Parts Extract, Fresh, Undried monograph & interactions

Other (inactive) ingredients: Cane Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wormwood by Herb Pharm Drug Interactions

Want to check YOUR meds against Wormwood?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Wormwood Flowering Aerial Parts Extract, Fresh, Undried 50

Individual Drug Interactions

The ingredients in Wormwood interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wormwood interact with drugs. Each result below shows which ingredient is responsible. Wormwood Flowering Aerial Parts Extract, Fresh, Undried

Each ingredient & the kinds of drugs it affects

For each ingredient in Wormwood with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wormwood Flowering Aerial Parts Extract, Fresh, Undried1 drug type · 50 drugs

Anticonvulsants

Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.

Likelihood Possible Evidence D
Wormwood Flowering Aerial Parts Extract, Fresh, Undried full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wormwood, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Wormwood by Herb Pharm: Common Questions

Does Wormwood by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Wormwood has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wormwood contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Wormwood is considered unsafe in pregnancy because it may stimulate the uterus. While breastfeeding, there isn't enough safety information, so it's best avoided then too. Talk with your doctor or pharmacist about safer options.
What are the side effects?
The most common ones are nausea, vomiting, and muscle aches from the oil in wormwood leaves. Serious but rare effects include kidney toxicity, severe muscle breakdown, and seizures. Long-term heavy use carries risks of hallucinations, tremors, paralysis, and brain damage.
How long can I safely use this?
Short-term use of properly prepared wormwood may be acceptable, but thujone — a neurotoxin in the plant — accumulates and becomes toxic at higher amounts. We'd advise keeping use brief and talking with your pharmacist about a safe duration for your situation.
Does wormwood actually work for digestive problems?
The evidence isn't there yet. For indigestion, Crohn disease, biliary disorders, and the other conditions it's traditionally used for, we don't hold reliable evidence it works. If you're dealing with a digestive issue, your doctor or pharmacist can suggest options with better evidence behind them.
Is this safe to use with my seizure medication?
Not without checking first. Wormwood contains thujone, which has effects similar to seizure triggers, and it may interfere with how anticonvulsants work. Use the interaction checker on this page for your exact medication, then talk with your pharmacist or doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wormwood is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wormwood label
Go deeper

The Full Monographs Behind Wormwood’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wormwood

Interacts with 50 drugs

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It contains thujone, which can be toxic in...

Read the full Wormwood monograph →
Sources

Sources & How We Checked

Wormwood's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team