Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Yohimbe 750 mg with Avena Sativa Ingredients & Drug Interactions

by herbscience

Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Yohimbe 750 mg with Avena Sativa is a dietary supplement by herbscience with 3 active ingredients. Its ingredients are commonly taken for enlarged prostate (bph) symptoms, seasonal allergies, joint pain and arthritis.Based on those ingredients, 1,204 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Yohimbe, Stinging Nettle, Avena sativa. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Yohimbe 750 mg with Avena Sativa by herbscience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “Stinging Nettle” is listed as a grouped ingredient — the label gives one combined amount (400 mg) without saying how much of each component you get.
  • “Yohimbe” is listed as a grouped ingredient — the label gives one combined amount (750 mg) without saying how much of each component you get.
  • “Avena sativa” is listed as a grouped ingredient — the label gives one combined amount (180 mg) without saying how much of each component you get.

This product contains 3 active ingredients: a yohimbe extract (standardized to 10:1 concentration), an oat extract (4:1 concentration), and a stinging nettle extract (4:1 concentration). Yohimbe is included for its stimulant effects, oats for their potential heart and cholesterol benefits, and stinging nettle for its traditional use in supporting overall wellness.

The remaining ingredients are inactive — fillers and binders like microcrystalline cellulose, dicalcium phosphate, and silica that help form and stabilize the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support male function.
  • We looked for evidence on: Erectile dysfunction (ED), Benign prostatic hyperplasia (BPH), Sexual performance, Low libido.
  • The closest evidence on file: Stinging Nettle is rated "Insufficient Reliable Evidence To Rate" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Yohimbe is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence for what this product actually does is limited. Yohimbe has insufficient reliable evidence to support its use for obesity, low blood pressure on standing (orthostatic hypotension), or sexual side effects from antidepressants.

The oat extract is likely effective for lowering cholesterol and supporting heart health, based on clinical evidence. Stinging nettle shows possibly effective evidence for blood sugar control in diabetes but insufficient evidence for allergies, anemia, asthma, prostate health, or gum inflammation.

So while the oat component has solid support, the yohimbe claims lack strong evidence, and stinging nettle's benefits beyond blood sugar are not well established in the data we hold.

The evidence, ingredient by ingredient Stinging Nettle Yohimbe Oats

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Yohimbe carries serious cautions. It can cause dangerous heart and blood pressure effects, and because supplement potency is unpredictable, the risk is hard to predict.

Common side effects from yohimbine — the active compound — include anxiety, agitation, sweating, diarrhea, flushing, headache, high blood pressure, increased urination, nausea, rapid heart rate, tremors, dizziness, and vomiting. Rare but serious effects include hypertensive crisis (severely high blood pressure requiring emergency care), heart rhythm problems, fluid retention, and chest discomfort.

Yohimbe is unsafe in pregnancy and should be avoided while breastfeeding. Oats in food form are generally well tolerated and considered safe in pregnancy and while breastfeeding, though concentrated oat supplements are less studied.

Common side effects are bloating, gas, and abdominal distention — usually manageable by increasing your dose slowly. Stinging nettle is generally well tolerated but is best avoided in pregnancy and during breastfeeding due to insufficient safety data.

It can cause constipation or diarrhea, and rare cases of liver injury have been reported.

Side effects, ingredient by ingredient Stinging Nettle Yohimbe Oats

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Stinging Nettle, Yohimbe, Oats.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 1,205 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, talk with your pharmacist if you take monoamine oxidase inhibitors (MAOIs) for depression — this is a Major-severity interaction. Also check with them if you're on blood pressure medications, heart drugs, stimulants, tricyclic antidepressants, antipsychotics, diabetes medications, insulin, diuretics, lithium, or blood thinners like warfarin.

Additionally, tell your pharmacist about any medications metabolized by liver enzymes (CYP2D6 or CYP3A4), as yohimbe may slow how your body clears them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Consider this product only if you don't take any heart, blood pressure, mood, diabetes, or stimulant medications — and even then, yohimbe's unpredictable strength and serious side effects make it a high-risk choice. If you take any prescription drugs, especially for heart, blood pressure, mood, or blood sugar, talk with your pharmacist or doctor before starting.

Pregnant or breastfeeding? Skip the yohimbe entirely.

The oat and nettle components are generally safer, but this product's yohimbe content makes it a caution overall.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Yohimbe 750 mg with Avena Sativa, straight from the product label.

Brand herbscience
Barcode (UPC) 035046041922
Net contents 60 Caplet(s)
Market status On market
Date entered into DSLD Mar 23, 2012
DSLD ID 7111
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Yohimbe 750 mg with Avena Sativa by herbscience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
UPC/BARCODE
035046041922
IngredientAmount% DV
Stinging Nettle400 mg--
Yohimbe750 mg--
standardized 10:1 {Yohimbe} extract75 mg--
Avena sativa180 mg--
4:1 {Avena sativa} extract45 mg--
4:1 {Stinging Nettle} extract100 mg--

Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Wheat Germ, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BLUEPRINT BOTANICALS(TM)

At herbscience(TM), we have found a way to combine high technology with age-old herbal tradition. The Blueprint Botanicals(TM) system begins with select herbs gathered from all over the world. Pre-tested, using advanced analytical methods, our herbal extracts are patiently concentrated utilizing time-tested methods. Once we have attained the highly standardized levels recommended by leading herbalists, our finished products are packaged and double-sealed for optimal freshness. This is your assurance of potency and purity. Blueprint Botanicals(TM) for herbscience(TM)- Perfecting the Science of Nature(TM).

(C) Copyright 1998 Windmill Consumer Products(TM)

General

TC# 54310602 ITEM# N4192

General Statements

support MALE FUNCTION

STANDARDIZED-FULL POTENCY

Seals/Symbols

(BB) BLUEPRINT BOTANICALS(TM)

Suggested/Recommended/Usage/Directions

DIRECTIONS: Take one caplet daily as a dietary supplement or as recommended by a healthcare professional.

Precautions

WARNING: Pregnant or lactating women should consult their physician prior to taking this product.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Protect from heat, light and moisture.

FDA Statement of Identity

herbal supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Yohimbe 750 mg with Avena Sativa by herbscience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Yohimbe 750 mg with Avena Sativa by herbscience

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Stinging Nettle

Interacts with
164 drugs
400 mg per serving

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...

Stinging Nettle monograph & interactions

Yohimbe

Interacts with
1,125 drugs
750 mg per serving

Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription...

Yohimbe monograph & interactions

Avena sativa

Interacts with
86 drugs
180 mg per serving

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a f...

Avena sativa monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Wheat Germ, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Yohimbe 750 mg with Avena Sativa by herbscience Drug Interactions

Want to check YOUR meds against Yohimbe 750 mg with Avena Sativa?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,204Drugs
9 Major 767 Moderate 428 Minor

Ingredients driving the most interactions

Yohimbe 1,125

Each ingredient & the kinds of drugs it affects

For each ingredient in Yohimbe 750 mg with Avena Sativa with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Yohimbe13 drug types · 1,125 drugs

Monoamine Oxidase Inhibitors (Maois)

Concomitant use of MAOIs with yohimbe can result in additive effects.
Yohimbine, a constituent of yohimbe, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO.

Likelihood Likely Evidence D
Antihypertensive Drugs

Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Yohimbine, a constituent of yohimbe, is an alpha-2 adrenoceptor antagonist and has been reported to increase blood pressure in clinical research. Theoretically, concomitant use of yohimbe and antihypertensive drugs can interfere with blood pressure control.

Likelihood Probable Evidence D
Clonidine (Catapres)

Theoretically, yohimbe might precipitate clonidine withdrawal.
Chronic clonidine use can downregulate alpha-2 adrenoreceptors. Animal research and one human case report suggest that concomitant administration of yohimbine, an alpha-2 adrenoceptor antagonist, may precipitate clonidine withdrawal and lead to sympathomimetic toxicity, including hypertensive crisis.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Inhibitors

CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP2D6 isoenzymes. Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine and reduces the clearance of yohimbine compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers..

Likelihood Probable Evidence B
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
In vitro research suggests that yohimbine, a constituent of yohimbe bark, inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Inhibitors

Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of yohimbine, a constituent of yohimbe bark.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP3A4 enzymes. Theoretically, drugs that inhibit CYP3A4 might increase the levels and adverse effects of yohimbine.

Likelihood Possible Evidence D
Paroxetine (Paxil)

Paroxetine decreases the clearance of yohimbine and may increase its effects.
Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine by about 350% and reduces the clearance of yohimbine by about 80% compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers. No significant changes in pharmacokinetic parameters of yohimbine were observed with coadministration of paroxetine in patients who are poor CYP2D6 metabolizers.

Likelihood Probable Evidence B
Phenothiazines

Theoretically, using yohimbine with phenothiazines might have additive effects.
Yohimbine, a constituent of yohimbe, has alpha-2 adrenergic antagonist effects. Theoretically, combining it with phenothiazines can cause additive alpha-2 adrenergic antagonism.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Yohimbine, a constituent of yohimbe, has sympathomimetic effects and increases blood pressure in a dose-dependent manner. Theoretically, taking yohimbe with stimulant drugs can have additive stimulant and hypertensive effects.

Likelihood Possible Evidence D
Tricyclic Antidepressants (Tcas)

Theoretically, taking yohimbe with TCAs can increase adverse effects.
A small clinical study in patients taking TCAs for at least 4 weeks shows that receiving doses of intravenous yohimbine 2.5-20 mg daily for up to 7 days precipitates severe anxiety, agitation, and tremor. The effects of yohimbe bark itself are unclear; oral yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical research.
Research in healthy adults shows that taking yohimbine, a constituent of yohimbe bark, in doses of 8 mg or more, seems to inhibit platelet aggregation in vitro by binding to the alpha-2 adrenoceptor. The effects of yohimbe bark itself are unclear; yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that yohimbe extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that yohimbe extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D

Stinging Nettle4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D

Avena sativa2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Yohimbe 750 mg with Avena Sativa, from the product label.

herbscience

See all herbscience products
Name
Windmill Consumer Products
City
West Caldwell
State
NJ
ZipCode
07006
Pharmacist Counseling Corner

Yohimbe 750 mg with Avena Sativa by herbscience: Common Questions

Does Yohimbe 750 mg with Avena Sativa by herbscience interact with any medications?
Yes. Based on its ingredients, Yohimbe 750 mg with Avena Sativa has a known interaction with 1,204 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Yohimbe 750 mg with Avena Sativa contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does yohimbe really work for sexual performance or weight loss?
According to the evidence available, there isn't enough reliable data to say yohimbe works for sexual side effects from antidepressants, weight loss, or low blood pressure on standing. The research just isn't there yet. That's why we rate it 'insufficient reliable evidence' for those uses.
What are the most common side effects I might notice?
Yohimbine can cause anxiety, agitation, sweating, tremors, nausea, diarrhea, headache, dizziness, and rapid heart rate. The oats may cause bloating and gas, especially when you first start. These tend to be dose-related — starting low and increasing slowly may help.
Is it safe to take this while pregnant or breastfeeding?
No. Yohimbe is unsafe in pregnancy and should be avoided while breastfeeding because safety hasn't been established. The oat and nettle extracts are less clear, but given the yohimbe content, this product isn't recommended for either.
Why does the interaction list mention so many blood pressure and heart drugs?
Yohimbine raises blood pressure in a dose-dependent way and has stimulant effects. It can work against blood pressure meds, add to the effects of stimulants, and trigger dangerous heart rhythms or blood pressure spikes, especially in combination with certain cardiac or psychiatric medications.
What's the difference between yohimbe and yohimbine?
Yohimbine is the active chemical compound found in yohimbe bark. When you take yohimbe, you're getting yohimbine — but the amount varies unpredictably from product to product, which makes side effects and interactions harder to predict.
Is the oat extract in this product the same as eating oatmeal?
No — this is a 4:1 concentrate, so it's much more potent than regular oatmeal. Food oats are safe in pregnancy and while breastfeeding, but concentrated oat supplements are less studied. However, the main concern with this product is the yohimbe, not the oat.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Yohimbe 750 mg with Avena Sativa label
Sources

Sources & How We Checked

Yohimbe 750 mg with Avena Sativa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 102 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
  11. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  12. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
  13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
  14. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  15. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
  16. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  17. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
  18. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
  19. Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  20. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
  21. Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
  22. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
  23. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed

See these in context on the Stinging Nettle monograph →

Yohimbe 66 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol 1980;60:85-7.
  6. Teloken C, Rhoden EL, Sogari P, et al. Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J Urol 1998;159:122-4. PubMed
  7. Jacobsen FM. Fluoxetine-induced sexual dysfunction and an open trial of yohimbine. J Clin Psychiatry 1992;53:119-22.
  8. Hollander E, McCarley A. Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. J Clin Psychiatry 1992;53:207-9.
  9. Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed
  10. Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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