Yohimbe 750 mg with Avena Sativa Ingredients & Drug Interactions
by herbscience
What is this page for?
First and foremost: checking Yohimbe 750 mg with Avena Sativa against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Yohimbe 750 mg with Avena Sativa is a dietary supplement by herbscience with 3 active ingredients. Its ingredients are commonly taken for enlarged prostate (bph) symptoms, seasonal allergies, joint pain and arthritis.Based on those ingredients, 1,204 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Yohimbe, Stinging Nettle, Avena sativa. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Yohimbe 750 mg with Avena Sativa by herbscience
Ask about any prescription or over-the-counter medication and we check it for interactions with Yohimbe 750 mg with Avena Sativa by herbscience — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Yohimbe 750 mg with Avena Sativa by herbscience
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 3 active ingredients: a yohimbe extract (standardized to 10:1 concentration), an oat extract (4:1 concentration), and a stinging nettle extract (4:1 concentration). Yohimbe is included for its stimulant effects, oats for their potential heart and cholesterol benefits, and stinging nettle for its traditional use in supporting overall wellness.
The remaining ingredients are inactive — fillers and binders like microcrystalline cellulose, dicalcium phosphate, and silica that help form and stabilize the tablet.
Does it work?
Not established
The evidence for what this product actually does is limited. Yohimbe has insufficient reliable evidence to support its use for obesity, low blood pressure on standing (orthostatic hypotension), or sexual side effects from antidepressants.
The oat extract is likely effective for lowering cholesterol and supporting heart health, based on clinical evidence. Stinging nettle shows possibly effective evidence for blood sugar control in diabetes but insufficient evidence for allergies, anemia, asthma, prostate health, or gum inflammation.
So while the oat component has solid support, the yohimbe claims lack strong evidence, and stinging nettle's benefits beyond blood sugar are not well established in the data we hold.
How safe is it?
Well-documented data
Yohimbe carries serious cautions. It can cause dangerous heart and blood pressure effects, and because supplement potency is unpredictable, the risk is hard to predict.
Common side effects from yohimbine — the active compound — include anxiety, agitation, sweating, diarrhea, flushing, headache, high blood pressure, increased urination, nausea, rapid heart rate, tremors, dizziness, and vomiting. Rare but serious effects include hypertensive crisis (severely high blood pressure requiring emergency care), heart rhythm problems, fluid retention, and chest discomfort.
Yohimbe is unsafe in pregnancy and should be avoided while breastfeeding. Oats in food form are generally well tolerated and considered safe in pregnancy and while breastfeeding, though concentrated oat supplements are less studied.
Common side effects are bloating, gas, and abdominal distention — usually manageable by increasing your dose slowly. Stinging nettle is generally well tolerated but is best avoided in pregnancy and during breastfeeding due to insufficient safety data.
It can cause constipation or diarrhea, and rare cases of liver injury have been reported.
Meds to double-check
Major interaction found
Before taking this product, talk with your pharmacist if you take monoamine oxidase inhibitors (MAOIs) for depression — this is a Major-severity interaction. Also check with them if you're on blood pressure medications, heart drugs, stimulants, tricyclic antidepressants, antipsychotics, diabetes medications, insulin, diuretics, lithium, or blood thinners like warfarin.
Additionally, tell your pharmacist about any medications metabolized by liver enzymes (CYP2D6 or CYP3A4), as yohimbe may slow how your body clears them.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
Consider this product only if you don't take any heart, blood pressure, mood, diabetes, or stimulant medications — and even then, yohimbe's unpredictable strength and serious side effects make it a high-risk choice. If you take any prescription drugs, especially for heart, blood pressure, mood, or blood sugar, talk with your pharmacist or doctor before starting.
Pregnant or breastfeeding? Skip the yohimbe entirely.
The oat and nettle components are generally safer, but this product's yohimbe content makes it a caution overall.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Yohimbe 750 mg with Avena Sativa, straight from the product label.
| Brand | herbscience |
|---|---|
| Barcode (UPC) | 035046041922 |
| Net contents | 60 Caplet(s) |
| Market status | On market |
| Date entered into DSLD | Mar 23, 2012 |
| DSLD ID | 7111 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Yohimbe 750 mg with Avena Sativa by herbscience, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Stinging Nettle | 400 mg | -- |
| Yohimbe | 750 mg | -- |
| standardized 10:1 {Yohimbe} extract | 75 mg | -- |
| Avena sativa | 180 mg | -- |
| 4:1 {Avena sativa} extract | 45 mg | -- |
| 4:1 {Stinging Nettle} extract | 100 mg | -- |
Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Wheat Germ, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Pharmaceutical Glaze
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
BLUEPRINT BOTANICALS(TM)
At herbscience(TM), we have found a way to combine high technology with age-old herbal tradition. The Blueprint Botanicals(TM) system begins with select herbs gathered from all over the world. Pre-tested, using advanced analytical methods, our herbal extracts are patiently concentrated utilizing time-tested methods. Once we have attained the highly standardized levels recommended by leading herbalists, our finished products are packaged and double-sealed for optimal freshness. This is your assurance of potency and purity. Blueprint Botanicals(TM) for herbscience(TM)- Perfecting the Science of Nature(TM).
(C) Copyright 1998 Windmill Consumer Products(TM)
General
TC# 54310602 ITEM# N4192
General Statements
support MALE FUNCTION
STANDARDIZED-FULL POTENCY
Seals/Symbols
(BB) BLUEPRINT BOTANICALS(TM)
Suggested/Recommended/Usage/Directions
DIRECTIONS: Take one caplet daily as a dietary supplement or as recommended by a healthcare professional.
Precautions
WARNING: Pregnant or lactating women should consult their physician prior to taking this product.
Keep out of reach of children.
Do not use if seal is broken.
Storage
Protect from heat, light and moisture.
FDA Statement of Identity
herbal supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Yohimbe 750 mg with Avena Sativa by herbscience label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Yohimbe 750 mg with Avena Sativa by herbscience
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Stinging Nettle
Interacts with164 drugs
Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...
Stinging Nettle monograph & interactionsYohimbe
Interacts with1,125 drugs
Yohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription...
Yohimbe monograph & interactionsAvena sativa
Interacts with86 drugs
Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a f...
Avena sativa monograph & interactionsOther (inactive) ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Wheat Germ, Croscarmellose Sodium, Stearic Acid, Silica, Magnesium Stearate, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.
Yohimbe 750 mg with Avena Sativa by herbscience Drug Interactions
HelloPharmacist Interaction Report
Yohimbe 750 mg with Avena Sativa by herbscience has documented interactions with a significant number of medications, mainly through its yohimbe content.
The most serious concern is with monoamine oxidase inhibitors (MAOIs) — a Major-severity interaction. Yohimbine, the active compound in yohimbe, has MAOI-like effects itself, and combining them can cause dangerous additive effects.
Read the full breakdown — every affected drug type, severity by severity
Yohimbe also has Moderate-severity interactions with blood pressure medications (antihypertensives), stimulant drugs, heart and blood vessel medications, antidepressants (particularly tricyclic antidepressants), and certain psychiatric medications (phenothiazines). It can also affect how your liver processes other drugs through two enzyme systems: CYP2D6 and CYP3A4.
The oat extract in this product may lower blood sugar, creating a Moderate-severity interaction with diabetes medications and insulin; stinging nettle similarly may lower blood sugar and interfere with diuretics, lithium, and blood thinners like warfarin.
Altogether, these interactions span 1,191 individual medications. Because yohimbe's potency varies unpredictably from batch to batch, the strength of these interactions can be hard to predict.
If you take any prescription medication — especially for heart, blood pressure, mood, or diabetes — check your exact drugs with the tool below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Yohimbe 750 mg with Avena Sativa?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Yohimbe 750 mg with Avena Sativa interact with 1,204 drugs. Click any drug to see the details.
3 of the 3 ingredients in Yohimbe 750 mg with Avena Sativa interact with drugs. Each result below shows which ingredient is responsible. Yohimbe Stinging Nettle Avena sativa
AmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois), Cytochrome P450 2d6 (cyp2d6) Substrates +1 Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Amphetamine interactionIsocarboxazidMarplan
How Isocarboxazid interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Isocarboxazid interactionMoclobemideManerix, Moclobemide
How Moclobemide interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois), Cytochrome P450 2d6 (cyp2d6) Inhibitors Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Moclobemide interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Ozanimod Hydrochloride interactionPhenelzine SulfateNardil
How Phenelzine Sulfate interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Phenelzine Sulfate interactionRasagilineAzilect
How Rasagiline interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois), Cytochrome P450 1a2 (cyp1a2) Substrates Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Rasagiline interactionSafinamide MesylateXadago
How Safinamide Mesylate interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Safinamide Mesylate interactionSelegilineCarbex, Eldepryl, Emsam, Zelapar
How Selegiline interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Selegiline interactionTranylcypromineParnate
How Tranylcypromine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Concomitant use of MAOIs with yohimbe can result in additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Tranylcypromine interactionAbametapirXeglyze
How Abametapir interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 3a4 (cyp3a4) Inhibitors Moderate
Interaction Summary
Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of yohimbine, a constituent of yohimbe bark.
Read the full Standardized 10:1 {yohimbe} Extract + Abametapir interactionAbiraterone
How Abiraterone interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 3a4 (cyp3a4) Inhibitors +1 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 2d6 (cyp2d6) Inhibitors, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
Read the full Standardized 10:1 {yohimbe} Extract + Abiraterone Acetate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Yohimbe 750 mg with Avena Sativa — through 2 ingredients. Tap an ingredient for the detail:
4:1 {avena Sativa} ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Read the full 4:1 {avena Sativa} Extract + Acarbose interaction4:1 {stinging Nettle} ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Read the full 4:1 {stinging Nettle} Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Read the full Standardized 10:1 {yohimbe} Extract + Acebutolol interactionAcepromazineAtravet
How Acepromazine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractPhenothiazines Moderate
Interaction Summary
Theoretically, using yohimbine with phenothiazines might have additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Acepromazine interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical research.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractStimulant Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Stimulant Drugs +1 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +3 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractStimulant Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Yohimbe 750 mg with Avena Sativa — through 2 ingredients. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Caffeine, Pyrilamine interaction4:1 {stinging Nettle} ExtractDiuretic Drugs Moderate
Interaction Summary
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Read the full 4:1 {stinging Nettle} Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 2d6 (cyp2d6) Inhibitors, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Stimulant Drugs +3 Moderate
Interaction Summary
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Yohimbe 750 mg with Avena Sativa — through 1 ingredient. Tap an ingredient for the detail:
Standardized 10:1 {yohimbe} ExtractCytochrome P450 2d6 (cyp2d6) Inhibitors, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
Read the full Standardized 10:1 {yohimbe} Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Yohimbe 750 mg with Avena Sativa with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Yohimbe
Monoamine Oxidase Inhibitors (Maois)
Concomitant use of MAOIs with yohimbe can result in additive effects.
Yohimbine, a constituent of yohimbe, has MAO inhibitory effects. At high doses, yohimbine is a non-selective inhibitor of MAO.
Antihypertensive Drugs
Theoretically, yohimbe might reduce the effects of antihypertensive drugs.
Yohimbine, a constituent of yohimbe, is an alpha-2 adrenoceptor antagonist and has been reported to increase blood pressure in clinical research. Theoretically, concomitant use of yohimbe and antihypertensive drugs can interfere with blood pressure control.
Clonidine (Catapres)
Theoretically, yohimbe might precipitate clonidine withdrawal.
Chronic clonidine use can downregulate alpha-2 adrenoreceptors. Animal research and one human case report suggest that concomitant administration of yohimbine, an alpha-2 adrenoceptor antagonist, may precipitate clonidine withdrawal and lead to sympathomimetic toxicity, including hypertensive crisis.
Cytochrome P450 2D6 (Cyp2D6) Inhibitors
CYP2D6 inhibitors may increase the levels and adverse effects of yohimbine, a constituent of yohimbe.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP2D6 isoenzymes. Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine and reduces the clearance of yohimbine compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers..
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, yohimbe might increase the levels and adverse effects of CYP2D6 substrates.
In vitro research suggests that yohimbine, a constituent of yohimbe bark, inhibits CYP2D6 enzyme activity.
Cytochrome P450 3A4 (Cyp3A4) Inhibitors
Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of yohimbine, a constituent of yohimbe bark.
In vitro and clinical research shows that the yohimbe bark constituent, yohimbine, is metabolized by CYP3A4 enzymes. Theoretically, drugs that inhibit CYP3A4 might increase the levels and adverse effects of yohimbine.
Paroxetine (Paxil)
Paroxetine decreases the clearance of yohimbine and may increase its effects.
Paroxetine, a cytochrome P450 (CYP) 2D6 inhibitor, increases the maximum serum concentration of yohimbine by about 350% and reduces the clearance of yohimbine by about 80% compared to yohimbine alone in patients who are extensive CYP2D6 metabolizers. No significant changes in pharmacokinetic parameters of yohimbine were observed with coadministration of paroxetine in patients who are poor CYP2D6 metabolizers.
Phenothiazines
Theoretically, using yohimbine with phenothiazines might have additive effects.
Yohimbine, a constituent of yohimbe, has alpha-2 adrenergic antagonist effects. Theoretically, combining it with phenothiazines can cause additive alpha-2 adrenergic antagonism.
Stimulant Drugs
Theoretically, taking yohimbe with stimulant drugs can have additive effects.
Yohimbine, a constituent of yohimbe, has sympathomimetic effects and increases blood pressure in a dose-dependent manner. Theoretically, taking yohimbe with stimulant drugs can have additive stimulant and hypertensive effects.
Tricyclic Antidepressants (Tcas)
Theoretically, taking yohimbe with TCAs can increase adverse effects.
A small clinical study in patients taking TCAs for at least 4 weeks shows that receiving doses of intravenous yohimbine 2.5-20 mg daily for up to 7 days precipitates severe anxiety, agitation, and tremor. The effects of yohimbe bark itself are unclear; oral yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.
Anticoagulant/Antiplatelet Drugs
Theoretically, combining yohimbe bark with antiplatelet or anticoagulant drugs might have additive effects; however, this has not been reported in clinical research.
Research in healthy adults shows that taking yohimbine, a constituent of yohimbe bark, in doses of 8 mg or more, seems to inhibit platelet aggregation in vitro by binding to the alpha-2 adrenoceptor. The effects of yohimbe bark itself are unclear; yohimbe bark contains 0.6% to 1.38% yohimbine, but it is unclear how much is absorbed.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, yohimbe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that yohimbe extract induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, yohimbe might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that yohimbe extract induces CYP3A4 enzymes.
Stinging Nettle
Antidiabetes Drugs
Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.
Diuretic Drugs
Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.
Lithium
Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.
Warfarin (Coumadin)
There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.
Avena sativa
Antidiabetes Drugs
Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.
Insulin
Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.
Brand information
Manufacturer and brand details for Yohimbe 750 mg with Avena Sativa, from the product label.
herbscience
See all herbscience products- Name
- Windmill Consumer Products
- City
- West Caldwell
- State
- NJ
- ZipCode
- 07006
Yohimbe 750 mg with Avena Sativa by herbscience: Common Questions
Does Yohimbe 750 mg with Avena Sativa by herbscience interact with any medications?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Yohimbe 750 mg with Avena Sativa’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Stinging Nettle
Interacts with 164 drugsStinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...
Read the full Stinging Nettle monograph → Herb & supplement monographYohimbe
Interacts with 1,125 drugsYohimbe is a West African tree bark that contains yohimbine, a compound mainly promoted for erectile dysfunction and as an aphrodisiac. A prescription form of yohimbine has some evidence for...
Read the full Yohimbe monograph → Herb & supplement monographOats
Interacts with 86 drugsOats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...
Read the full Oats monograph →Sources & How We Checked
Yohimbe 750 mg with Avena Sativa's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 102 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Stinging Nettle 23 references
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Yohimbe 66 references
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Oats 13 references
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