Bendamustine Injection
Generic name: Pronounced as (ben'' da mus' teen)
Medical Content Reviewed By HelloPharmacist Staff
Last Revised - 09/15/2019
On this page
- Why is this medication prescribed?
- How should this medicine be used?
- Other uses for this medicine
- What special precautions should I follow?
- What special dietary instructions should I follow?
- What should I do if I forget a dose?
- What side effects can this medication cause?
- What should I do in case of OVERDOSE?
- What OTHER INFORMATION should I know?
- Drug interactions
Why is this medication prescribed?
Bendamustine injection is used to treat chronic lymphocytic leukemia (CLL; a type of cancer of the white blood cells). Bendamustine injection is also used to treat a type of non-Hodgkins lymphoma (NHL: cancer that begins in a type of white blood cell that normally fights infection) that is slow spreading, but has continued to worsen during or after treatment with another medication. Bendamustine is in a class of medications called alkylating agents. It works by killing existing cancer cells and limiting the growth of new cancer cells.
How should this medicine be used?
Bendamustine comes as a solution (liquid) or as a powder to be mixed with liquid and injected intravenously (into a vein) over 10 minutes or infused intravenously over 30 or 60 minutes by a doctor or nurse in a medical office or hospital outpatient clinic. When bendamustine injection is used to treat CLL, it is usually injected once a day for 2 days, followed by 26 days when the medication is not given. This treatment period is called a cycle, and the cycle may be repeated every 28 days for as long as 6 cycles. When bendamustine injection is used to treat NHL, it is usually injected once a day for 2 days, followed by 19 days when the medication is not given. This treatment cycle may be repeated every 21 days for up to 8 cycles.
Your doctor may need to delay your treatment and adjust your dose if you experience certain side effects. Your doctor may also give you other medication(s) to prevent or treat certain side effects. Be sure to tell your doctor how you are feeling during your treatment with bendamustine injection.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before receiving bendamustine injection,
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tell your doctor and pharmacist if you are allergic to bendamustine, any other medications, or any of the ingredients in bendamustine injection. Ask your pharmacist for a list of the ingredients.
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tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: ciprofloxacin (Cipro), fluvoxamine (Luvox, and omeprazole (Prilosec). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may interact with bendamustine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
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tell your doctor if you have or have ever had cytomegalovirus infection (CMV; a viral infection that may cause symptoms in patients with weak immune systems), hepatitis B virus infection (HBV; an ongoing liver infection), tuberculosis (TB; a serious infection that affects the lungs and sometimes other parts of the body), herpes zoster (shingles; a rash that can occur in people who have had chickenpox in the past), or kidney or liver disease.
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tell your doctor if you are pregnant or plan to become pregnant, or if you plan to father a child. You or your partner should not become pregnant while you are receiving bendamustine injection. You should use birth control to prevent pregnancy in yourself or your partner during your treatment with bendamustine injection and for 3 months afterwards. Talk to your doctor about birth control methods that will work for you. If you or your partner becomes pregnant while receiving bendamustine injection, call your doctor. Bendamustine injection can harm the fetus.
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tell your doctor if you are breast-feeding. You should not breastfeed during your treatment with bendamustine.
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you should know that bendamustine injection may make you tired. Do not drive a car or operate machinery until you know how this medication affects you.
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tell your doctor if you use tobacco products. Smoking may decrease the effectiveness of this medication.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Call your doctor right away if you are unable to keep an appointment to receive a dose of bendamustine injection.
What side effects can this medication cause?
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Bendamustine injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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nausea
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vomiting
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diarrhea
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heartburn
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constipation
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stomach pain or swelling
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sores or white patches in the mouth
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dry mouth
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bad taste in the mouth or difficulty tasting food
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loss of appetite
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weight loss
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headache
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anxiety
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depression
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difficulty falling asleep or staying asleep
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back, bone, joint, arm or leg pain
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dry skin
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sweating
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night sweats
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Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
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pain in the place where the medication was injected
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hives
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rash
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itching
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blistering or peeling skin
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difficulty breathing or swallowing
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swelling of the eyes, face, lips, tongue, arms, hands, feet, ankles, or lower legs
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shortness of breath
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chest pain
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fast heartbeat
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excessive tiredness or weakness
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pale skin
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fever, chills, cough, or other signs of infection
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nausea; vomiting; unusual bleeding or bruising; yellowing of the skin or eyes, dark urine, or light colored stool; tenderness on the right upper side of the stomach
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Bendamustine injection may cause infertility in some men. This infertility may end after treatment, may last for several years, or may be permanent. Talk to your doctor about the risks of receiving this medication.
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Some people developed other types of cancer while they were using bendamustine injection. There is not enough information to tell whether bendamustine injection caused these cancers to develop. Talk to your doctor about the risks of receiving this medication.
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Bendamustine injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
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If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
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rapid, irregular, or pounding heartbeat
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to bendamustine injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Drug interactions
Drug | Interaction |
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Moxifloxacin | Moxifloxacin The metabolism of Bendamustine can be decreased when combined with Moxifloxacin. |
Insulin Glargine (rDNA origin) Injection | Insulin Glargine (rDNA origin) Injection The metabolism of Bendamustine can be increased when combined with Insulin glargine. |
Leflunomide | Leflunomide The risk or severity of adverse effects can be increased when Leflunomide is combined with Bendamustine. |
Nevirapine | Nevirapine The metabolism of Bendamustine can be decreased when combined with Nevirapine. |
Aminophylline | Aminophylline The metabolism of Bendamustine can be decreased when combined with Aminophylline. |
Anagrelide | Anagrelide The metabolism of Bendamustine can be decreased when combined with Anagrelide. |
Cilostazol | Cilostazol The metabolism of Bendamustine can be decreased when combined with Cilostazol. |
Clopidogrel | Clopidogrel The metabolism of Bendamustine can be decreased when combined with Clopidogrel. |
Erythromycin and Sulfisoxazole | Erythromycin and Sulfisoxazole The serum concentration of Bendamustine can be increased when it is combined with Erythromycin. |
Estrogen and Progestin (Oral Contraceptives) | Estrogen and Progestin (Oral Contraceptives) The metabolism of Bendamustine can be decreased when combined with Conjugated estrogens. |
Mycophenolate | Mycophenolate The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Bendamustine. |
Paregoric | Paregoric The serum concentration of Bendamustine can be increased when it is combined with Morphine. |
Prednisone | Prednisone The risk or severity of adverse effects can be increased when Prednisone is combined with Bendamustine. |
Ranitidine | Ranitidine The metabolism of Bendamustine can be decreased when combined with Ranitidine. |
Reserpine | Reserpine The serum concentration of Bendamustine can be increased when it is combined with Reserpine. |
Tacrolimus | Tacrolimus Tacrolimus may increase the immunosuppressive activities of Bendamustine. |
Tizanidine | Tizanidine The metabolism of Bendamustine can be decreased when combined with Tizanidine. |
Triamcinolone | Triamcinolone The risk or severity of adverse effects can be increased when Triamcinolone is combined with Bendamustine. |
Zolmitriptan | Zolmitriptan The metabolism of Bendamustine can be decreased when combined with Zolmitriptan. |
Famotidine Injection | Famotidine Injection The metabolism of Bendamustine can be decreased when combined with Famotidine. |
Fluconazole Injection | Fluconazole Injection The serum concentration of Bendamustine can be increased when it is combined with Fluconazole. |
Interferon Beta-1b Injection | Interferon Beta-1b Injection The risk or severity of adverse effects can be increased when Interferon beta-1b is combined with Bendamustine. |
Interferon Gamma-1b Injection | Interferon Gamma-1b Injection The risk or severity of adverse effects can be increased when Interferon gamma-1b is combined with Bendamustine. |
Levofloxacin Injection | Levofloxacin Injection The metabolism of Bendamustine can be decreased when combined with Levofloxacin. |
Meperidine Injection | Meperidine Injection The metabolism of Bendamustine can be increased when combined with Meperidine. |
Methylprednisolone Injection | Methylprednisolone Injection The risk or severity of adverse effects can be increased when Methylprednisolone is combined with Bendamustine. |
Metoclopramide Injection | Metoclopramide Injection The metabolism of Bendamustine can be decreased when combined with Metoclopramide. |
Morphine Injection | Morphine Injection The serum concentration of Bendamustine can be increased when it is combined with Morphine. |
Zidovudine Injection | Zidovudine Injection The risk or severity of adverse effects can be increased when Zidovudine is combined with Bendamustine. |
Cyclosporine | Cyclosporine Bendamustine may increase the immunosuppressive activities of Cyclosporine. |
Ondansetron | Ondansetron The metabolism of Bendamustine can be decreased when combined with Ondansetron. |
Enoxaparin Injection | Enoxaparin Injection The risk or severity of bleeding can be increased when Enoxaparin is combined with Bendamustine. |
Olanzapine | Olanzapine The metabolism of Bendamustine can be decreased when combined with Olanzapine. |
Alosetron | Alosetron The metabolism of Bendamustine can be decreased when combined with Alosetron. |
Hydroxychloroquine | Hydroxychloroquine The risk or severity of adverse effects can be increased when Hydroxychloroquine is combined with Bendamustine. |
Temozolomide | Temozolomide The risk or severity of adverse effects can be increased when Temozolomide is combined with Bendamustine. |
Anakinra | Anakinra The metabolism of Bendamustine can be increased when combined with Anakinra. |
Linezolid | Linezolid The risk or severity of adverse effects can be increased when Linezolid is combined with Bendamustine. |
Pentosan Polysulfate | Pentosan Polysulfate The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Bendamustine. |
Etanercept Injection | Etanercept Injection The metabolism of Bendamustine can be increased when combined with Etanercept. |
Modafinil | Modafinil The metabolism of Bendamustine can be increased when combined with Modafinil. |
Tenofovir | Tenofovir The serum concentration of Bendamustine can be increased when it is combined with Tenofovir. |
Sirolimus | Sirolimus The risk or severity of adverse effects can be increased when Sirolimus is combined with Bendamustine. |
Epirubicin | Epirubicin The risk or severity of adverse effects can be increased when Epirubicin is combined with Bendamustine. |
Zonisamide | Zonisamide The serum concentration of Bendamustine can be increased when it is combined with Zonisamide. |
Adalimumab Injection | Adalimumab Injection The metabolism of Bendamustine can be increased when combined with Adalimumab. |
Glatiramer Injection | Glatiramer Injection The risk or severity of adverse effects can be increased when Glatiramer is combined with Bendamustine. |
Vardenafil | Vardenafil The serum concentration of Bendamustine can be increased when it is combined with Vardenafil. |
Interferon Beta-1a Subcutaneous Injection | Interferon Beta-1a Subcutaneous Injection The metabolism of Bendamustine can be decreased when combined with Interferon beta-1a. |
Tegaserod | Tegaserod The metabolism of Bendamustine can be decreased when combined with Tegaserod. |
Frovatriptan | Frovatriptan The metabolism of Bendamustine can be decreased when combined with Frovatriptan. |
Gemifloxacin | Gemifloxacin The metabolism of Bendamustine can be decreased when combined with Gemifloxacin. |
Darbepoetin Alfa Injection | Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Bendamustine. |
Infliximab Injection | Infliximab Injection The metabolism of Bendamustine can be increased when combined with Infliximab. |
Duloxetine | Duloxetine The metabolism of Bendamustine can be decreased when combined with Duloxetine. |
Cinacalcet | Cinacalcet The metabolism of Bendamustine can be decreased when combined with Cinacalcet. |
Natalizumab Injection | Natalizumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Natalizumab. |
Erlotinib | Erlotinib The metabolism of Bendamustine can be decreased when combined with Erlotinib. |
Palifermin | Palifermin The therapeutic efficacy of Palifermin can be decreased when used in combination with Bendamustine. |
Entecavir | Entecavir The metabolism of Bendamustine can be decreased when combined with Entecavir. |
Peginterferon Alfa-2a Injection | Peginterferon Alfa-2a Injection The risk or severity of adverse effects can be increased when Peginterferon alfa-2a is combined with Bendamustine. |
Peginterferon Alfa-2b (PEG-Intron) | Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Bendamustine can be increased when it is combined with Peginterferon alfa-2b. |
Ramelteon | Ramelteon The metabolism of Bendamustine can be decreased when combined with Ramelteon. |
Deferasirox | Deferasirox The serum concentration of Bendamustine can be increased when it is combined with Deferasirox. |
Phenylephrine | Phenylephrine The metabolism of Bendamustine can be increased when combined with Phenylephrine. |
Tipranavir | Tipranavir The serum concentration of Bendamustine can be increased when it is combined with Tipranavir. |
Ranolazine | Ranolazine The serum concentration of Bendamustine can be increased when it is combined with Ranolazine. |
Abatacept Injection | Abatacept Injection The metabolism of Bendamustine can be increased when combined with Abatacept. |
Rasagiline | Rasagiline The metabolism of Bendamustine can be decreased when combined with Rasagiline. |
Imatinib | Imatinib The risk or severity of adverse effects can be increased when Imatinib is combined with Bendamustine. |
Sitagliptin | Sitagliptin The serum concentration of Bendamustine can be increased when it is combined with Sitagliptin. |
Bevacizumab Injection | Bevacizumab Injection The risk or severity of adverse effects can be increased when Bevacizumab is combined with Bendamustine. |
Paliperidone | Paliperidone The serum concentration of Bendamustine can be increased when it is combined with Paliperidone. |
Bortezomib | Bortezomib The risk or severity of adverse effects can be increased when Bortezomib is combined with Bendamustine. |
Clofarabine Injection | Clofarabine Injection The risk or severity of adverse effects can be increased when Clofarabine is combined with Bendamustine. |
Hepatitis B Vaccine | Hepatitis B Vaccine The therapeutic efficacy of Hepatitis B Vaccine (Recombinant) can be decreased when used in combination with Bendamustine. |
Influenza Vaccine, Inactivated or Recombinant | Influenza Vaccine, Inactivated or Recombinant The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Bendamustine. |
Influenza Vaccine, Live Intranasal | Influenza Vaccine, Live Intranasal The risk or severity of infection can be increased when Typhoid Vaccine Live is combined with Bendamustine. |
Live Shingles (Zoster) Vaccine (ZVL) | Live Shingles (Zoster) Vaccine (ZVL) The risk or severity of infection can be increased when Varicella Zoster Vaccine (Live/attenuated) is combined with Bendamustine. |
Insulin Glulisine (rDNA origin) Injection | Insulin Glulisine (rDNA origin) Injection The metabolism of Bendamustine can be increased when combined with Insulin glulisine. |
Oxaliplatin Injection | Oxaliplatin Injection The risk or severity of adverse effects can be increased when Oxaliplatin is combined with Bendamustine. |
Posaconazole | Posaconazole The serum concentration of Bendamustine can be increased when it is combined with Posaconazole. |
Primaquine | Primaquine The metabolism of Bendamustine can be increased when combined with Primaquine. |
Rituximab Injection | Rituximab Injection The risk or severity of adverse effects can be increased when Rituximab is combined with Bendamustine. |
Pemetrexed Injection | Pemetrexed Injection The risk or severity of adverse effects can be increased when Pemetrexed is combined with Bendamustine. |
Vorinostat | Vorinostat The risk or severity of adverse effects can be increased when Vorinostat is combined with Bendamustine. |
Sorafenib | Sorafenib The serum concentration of Bendamustine can be increased when it is combined with Sorafenib. |
Sunitinib | Sunitinib The risk or severity of adverse effects can be increased when Sunitinib is combined with Bendamustine. |
Lapatinib | Lapatinib The serum concentration of Bendamustine can be increased when it is combined with Lapatinib. |
Dasatinib | Dasatinib The risk or severity of adverse effects can be increased when Dasatinib is combined with Bendamustine. |
Mexiletine | Mexiletine The metabolism of Bendamustine can be decreased when combined with Mexiletine. |
Armodafinil | Armodafinil The metabolism of Bendamustine can be increased when combined with Armodafinil. |
Azacitidine Injection | Azacitidine Injection The risk or severity of adverse effects can be increased when Azacitidine is combined with Bendamustine. |
Temsirolimus | Temsirolimus The serum concentration of Bendamustine can be increased when it is combined with Temsirolimus. |
Nelarabine Injection | Nelarabine Injection The risk or severity of adverse effects can be increased when Nelarabine is combined with Bendamustine. |
Lenalidomide | Lenalidomide The risk or severity of adverse effects can be increased when Lenalidomide is combined with Bendamustine. |
Nilotinib | Nilotinib The serum concentration of Bendamustine can be increased when it is combined with Nilotinib. |
Toremifene | Toremifene The serum concentration of Bendamustine can be increased when it is combined with Toremifene. |
Bexarotene | Bexarotene The risk or severity of adverse effects can be increased when Bexarotene is combined with Bendamustine. |
Budesonide | Budesonide The risk or severity of adverse effects can be increased when Budesonide is combined with Bendamustine. |
Chloramphenicol Injection | Chloramphenicol Injection The risk or severity of adverse effects can be increased when Chloramphenicol is combined with Bendamustine. |
Decitabine Injection | Decitabine Injection The risk or severity of adverse effects can be increased when Decitabine is combined with Bendamustine. |
Etravirine | Etravirine The serum concentration of Bendamustine can be decreased when it is combined with Etravirine. |
Arsenic Trioxide Injection | Arsenic Trioxide Injection The risk or severity of adverse effects can be increased when Arsenic trioxide is combined with Bendamustine. |
Mitoxantrone Injection | Mitoxantrone Injection The risk or severity of adverse effects can be increased when Mitoxantrone is combined with Bendamustine. |
Tretinoin | Tretinoin The risk or severity of adverse effects can be increased when Tretinoin is combined with Bendamustine. |
Flecainide | Flecainide The metabolism of Bendamustine can be decreased when combined with Flecainide. |
Certolizumab Injection | Certolizumab Injection The metabolism of Bendamustine can be increased when combined with Certolizumab pegol. |
Ixabepilone Injection | Ixabepilone Injection The risk or severity of adverse effects can be increased when Ixabepilone is combined with Bendamustine. |
Irinotecan Injection | Irinotecan Injection The risk or severity of adverse effects can be increased when Irinotecan is combined with Bendamustine. |
Estramustine | Estramustine The risk or severity of adverse effects can be increased when Estramustine is combined with Bendamustine. |
Praziquantel | Praziquantel The metabolism of Bendamustine can be decreased when combined with Praziquantel. |
Alemtuzumab Injection (Chronic Lymphocytic Leukemia) | Alemtuzumab Injection (Chronic Lymphocytic Leukemia) The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Bendamustine. |
Silodosin | Silodosin The serum concentration of Bendamustine can be increased when it is combined with Silodosin. |
Dexrazoxane Injection | Dexrazoxane Injection The risk or severity of adverse effects can be increased when Dexrazoxane is combined with Bendamustine. |
Eltrombopag | Eltrombopag The metabolism of Bendamustine can be decreased when combined with Eltrombopag. |
Ibritumomab Injection | Ibritumomab Injection The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Bendamustine. |
Betaxolol | Betaxolol The metabolism of Bendamustine can be decreased when combined with Betaxolol. |
Prasugrel | Prasugrel The risk or severity of bleeding can be increased when Prasugrel is combined with Bendamustine. |
Everolimus | Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Bendamustine. |
Tolvaptan (low blood sodium) | Tolvaptan (low blood sodium) The serum concentration of Bendamustine can be increased when it is combined with Tolvaptan. |
Dronedarone | Dronedarone The serum concentration of Bendamustine can be increased when it is combined with Dronedarone. |
Pralatrexate Injection | Pralatrexate Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Pralatrexate. |
Romidepsin Injection | Romidepsin Injection The serum concentration of Bendamustine can be increased when it is combined with Romidepsin. |
Topotecan | Topotecan The risk or severity of adverse effects can be increased when Topotecan is combined with Bendamustine. |
Golimumab Injection | Golimumab Injection The metabolism of Bendamustine can be increased when combined with Golimumab. |
Pazopanib | Pazopanib The risk or severity of adverse effects can be increased when Pazopanib is combined with Bendamustine. |
Asenapine | Asenapine The metabolism of Bendamustine can be decreased when combined with Asenapine. |
Albendazole | Albendazole The metabolism of Bendamustine can be decreased when combined with Albendazole. |
Denosumab Injection | Denosumab Injection The risk or severity of adverse effects can be increased when Denosumab is combined with Bendamustine. |
Dabigatran | Dabigatran The risk or severity of bleeding can be increased when Dabigatran is combined with Bendamustine. |
Tocilizumab Injection | Tocilizumab Injection The metabolism of Bendamustine can be increased when combined with Tocilizumab. |
Fingolimod | Fingolimod Bendamustine may increase the immunosuppressive activities of Fingolimod. |
Eribulin Injection | Eribulin Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Eribulin. |
Cabazitaxel Injection | Cabazitaxel Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Cabazitaxel. |
Acetaminophen Injection | Acetaminophen Injection The metabolism of Bendamustine can be decreased when combined with Acetaminophen. |
Denileukin Diftitox Injection | Denileukin Diftitox Injection The risk or severity of adverse effects can be increased when Aldesleukin is combined with Bendamustine. |
Sipuleucel-T Injection | Sipuleucel-T Injection The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Bendamustine. |
Belimumab Injection | Belimumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Belimumab. |
Busulfan Injection | Busulfan Injection The risk or severity of adverse effects can be increased when Busulfan is combined with Bendamustine. |
Roflumilast | Roflumilast Roflumilast may increase the immunosuppressive activities of Bendamustine. |
Linagliptin | Linagliptin The serum concentration of Bendamustine can be increased when it is combined with Linagliptin. |
Telaprevir | Telaprevir The serum concentration of Bendamustine can be increased when it is combined with Glecaprevir. |
Cyclophosphamide Injection | Cyclophosphamide Injection The risk or severity of adverse effects can be increased when Cyclophosphamide is combined with Bendamustine. |
Abiraterone | Abiraterone The serum concentration of Bendamustine can be increased when it is combined with Abiraterone. |
Rivaroxaban | Rivaroxaban The serum concentration of Bendamustine can be increased when it is combined with Rivaroxaban. |
Ticagrelor | Ticagrelor The serum concentration of Bendamustine can be increased when it is combined with Ticagrelor. |
Brentuximab Vedotin Injection | Brentuximab Vedotin Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Brentuximab vedotin. |
Ruxolitinib | Ruxolitinib The risk or severity of adverse effects can be increased when Bendamustine is combined with Ruxolitinib. |
Vandetanib | Vandetanib The serum concentration of Bendamustine can be increased when it is combined with Vandetanib. |
Clobazam | Clobazam The serum concentration of Bendamustine can be increased when it is combined with Clobazam. |
Vemurafenib | Vemurafenib The serum concentration of Bendamustine can be increased when it is combined with Vemurafenib. |
Belatacept Injection | Belatacept Injection The risk or severity of adverse effects can be increased when Belatacept is combined with Bendamustine. |
Ivacaftor | Ivacaftor The serum concentration of Bendamustine can be increased when it is combined with Ivacaftor. |
Basiliximab Injection | Basiliximab Injection The risk or severity of adverse effects can be increased when Basiliximab is combined with Bendamustine. |
Axitinib | Axitinib The metabolism of Bendamustine can be decreased when combined with Axitinib. |
Crizotinib | Crizotinib The serum concentration of Bendamustine can be increased when it is combined with Crizotinib. |
Melphalan Injection | Melphalan Injection The risk or severity of adverse effects can be increased when Melphalan is combined with Bendamustine. |
Ambrisentan | Ambrisentan The serum concentration of Bendamustine can be increased when it is combined with Ambrisentan. |
Eculizumab Injection | Eculizumab Injection The risk or severity of adverse effects can be increased when Eculizumab is combined with Bendamustine. |
Fondaparinux Injection | Fondaparinux Injection The risk or severity of bleeding can be increased when Fondaparinux is combined with Bendamustine. |
Carfilzomib Injection | Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Bendamustine. |
Iloprost | Iloprost The risk or severity of bleeding can be increased when Iloprost is combined with Bendamustine. |
Enzalutamide | Enzalutamide The serum concentration of Bendamustine can be increased when it is combined with Enzalutamide. |
Mirabegron | Mirabegron The serum concentration of Bendamustine can be increased when it is combined with Mirabegron. |
Regorafenib | Regorafenib The serum concentration of Bendamustine can be increased when it is combined with Regorafenib. |
Bosutinib | Bosutinib The risk or severity of adverse effects can be increased when Bosutinib is combined with Bendamustine. |
Corticotropin, Repository Injection | Corticotropin, Repository Injection The risk or severity of adverse effects can be increased when Corticotropin is combined with Bendamustine. |
Teriflunomide | Teriflunomide The serum concentration of Bendamustine can be decreased when it is combined with Teriflunomide. |
Icosapent Ethyl | Icosapent Ethyl The risk or severity of bleeding can be increased when Icosapent ethyl is combined with Bendamustine. |
Tofacitinib | Tofacitinib Bendamustine may increase the immunosuppressive activities of Tofacitinib. |
Dimethyl Fumarate | Dimethyl Fumarate The risk or severity of adverse effects can be increased when Bendamustine is combined with Dimethyl fumarate. |
Ponatinib | Ponatinib The serum concentration of Ponatinib can be increased when it is combined with Bendamustine. |
Pomalidomide | Pomalidomide The risk or severity of adverse effects can be increased when Bendamustine is combined with Pomalidomide. |
Ado-trastuzumab Emtansine Injection | Ado-trastuzumab Emtansine Injection The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Bendamustine. |
Apixaban | Apixaban The serum concentration of Bendamustine can be increased when it is combined with Apixaban. |
Canagliflozin | Canagliflozin The serum concentration of Bendamustine can be increased when it is combined with Canagliflozin. |
Dabrafenib | Dabrafenib The serum concentration of Bendamustine can be increased when it is combined with Dabrafenib. |
Dolutegravir | Dolutegravir The serum concentration of Bendamustine can be increased when it is combined with Dolutegravir. |
Afatinib | Afatinib The serum concentration of Bendamustine can be increased when it is combined with Afatinib. |
Perampanel | Perampanel The metabolism of Perampanel can be decreased when combined with Bendamustine. |
Ibrutinib | Ibrutinib The risk or severity of adverse effects can be increased when Bendamustine is combined with Ibrutinib. |
Lomitapide | Lomitapide The serum concentration of Bendamustine can be increased when it is combined with Lomitapide. |
Obinutuzumab Injection | Obinutuzumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Obinutuzumab. |
Simeprevir | Simeprevir The serum concentration of Bendamustine can be increased when it is combined with Simeprevir. |
Sofosbuvir | Sofosbuvir The serum concentration of Bendamustine can be increased when it is combined with Sofosbuvir. |
Dapagliflozin | Dapagliflozin The metabolism of Bendamustine can be decreased when combined with Dapagliflozin. |
Apremilast | Apremilast The metabolism of Bendamustine can be increased when combined with Apremilast. |
Ceritinib | Ceritinib The serum concentration of Bendamustine can be increased when it is combined with Ceritinib. |
Siltuximab Injection | Siltuximab Injection The metabolism of Bendamustine can be increased when combined with Siltuximab. |
Vedolizumab Injection | Vedolizumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Vedolizumab. |
Belinostat Injection | Belinostat Injection The risk or severity of adverse effects can be increased when Belinostat is combined with Bendamustine. |
Idelalisib | Idelalisib The risk or severity of adverse effects can be increased when Bendamustine is combined with Idelalisib. |
Vorapaxar | Vorapaxar The serum concentration of Bendamustine can be increased when it is combined with Vorapaxar. |
Suvorexant | Suvorexant The serum concentration of Bendamustine can be increased when it is combined with Suvorexant. |
Edoxaban | Edoxaban The serum concentration of Bendamustine can be increased when it is combined with Edoxaban. |
Peginterferon Beta-1a Injection | Peginterferon Beta-1a Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Peginterferon beta-1a. |
Olaparib | Olaparib The risk or severity of adverse effects can be increased when Bendamustine is combined with Olaparib. |
Blinatumomab Injection | Blinatumomab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Blinatumomab. |
Tasimelteon | Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Bendamustine. |
Pirfenidone | Pirfenidone The risk or severity of adverse effects can be increased when Pirfenidone is combined with Bendamustine. |
Nintedanib | Nintedanib The serum concentration of Bendamustine can be increased when it is combined with Nintedanib. |
Secukinumab Injection | Secukinumab Injection The metabolism of Bendamustine can be increased when combined with Secukinumab. |
Palbociclib | Palbociclib The serum concentration of Palbociclib can be increased when it is combined with Bendamustine. |
Insulin Human Inhalation | Insulin Human Inhalation The metabolism of Bendamustine can be increased when combined with Insulin human. |
Lenvatinib | Lenvatinib The metabolism of Bendamustine can be decreased when combined with Lenvatinib. |
Panobinostat | Panobinostat The risk or severity of adverse effects can be increased when Panobinostat is combined with Bendamustine. |
Dinutuximab Injection | Dinutuximab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Dinutuximab. |
Haloperidol Injection | Haloperidol Injection The metabolism of Bendamustine can be decreased when combined with Haloperidol. |
Isavuconazonium Injection | Isavuconazonium Injection The serum concentration of Bendamustine can be increased when it is combined with Isavuconazonium. |
Flibanserin | Flibanserin The serum concentration of Bendamustine can be increased when it is combined with Flibanserin. |
Rolapitant | Rolapitant The serum concentration of Bendamustine can be increased when it is combined with Rolapitant. |
Prednisolone | Prednisolone The risk or severity of adverse effects can be increased when Prednisolone is combined with Bendamustine. |
Daclatasvir | Daclatasvir The serum concentration of Bendamustine can be increased when it is combined with Daclatasvir. |
Insulin Degludec (rDNA Origin) Injection | Insulin Degludec (rDNA Origin) Injection The metabolism of Bendamustine can be increased when combined with Insulin degludec. |
Cobimetinib | Cobimetinib The serum concentration of Bendamustine can be increased when it is combined with Cobimetinib. |
Mepolizumab Injection | Mepolizumab Injection The risk or severity of adverse effects can be increased when Mepolizumab is combined with Bendamustine. |
Trabectedin Injection | Trabectedin Injection The risk or severity of adverse effects can be increased when Trabectedin is combined with Bendamustine. |
Osimertinib | Osimertinib The serum concentration of Bendamustine can be decreased when it is combined with Osimertinib. |
Dexamethasone Injection | Dexamethasone Injection The risk or severity of adverse effects can be increased when Dexamethasone is combined with Bendamustine. |
Defibrotide Injection | Defibrotide Injection The risk or severity of bleeding can be increased when Defibrotide is combined with Bendamustine. |
Ixekizumab Injection | Ixekizumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Ixekizumab. |
Venetoclax | Venetoclax The serum concentration of Bendamustine can be increased when it is combined with Venetoclax. |
Cobicistat | Cobicistat The serum concentration of Bendamustine can be increased when it is combined with Cobicistat. |
Selexipag | Selexipag The serum concentration of Bendamustine can be increased when it is combined with Selexipag. |
Obeticholic Acid | Obeticholic Acid The risk or severity of adverse effects can be increased when Obeticholic acid is combined with Bendamustine. |
Rucaparib | Rucaparib The serum concentration of Rucaparib can be increased when it is combined with Bendamustine. |
Brodalumab Injection | Brodalumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Brodalumab. |
Doxepin (Insomnia) | Doxepin (Insomnia) The metabolism of Bendamustine can be decreased when combined with Doxepin. |
Deflazacort | Deflazacort The risk or severity of adverse effects can be increased when Bendamustine is combined with Deflazacort. |
Safinamide | Safinamide The metabolism of Bendamustine can be decreased when combined with Safinamide. |
Ocrelizumab Injection | Ocrelizumab Injection Ocrelizumab may increase the immunosuppressive activities of Bendamustine. |
Sarilumab Injection | Sarilumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Sarilumab. |
Midostaurin | Midostaurin The serum concentration of Bendamustine can be increased when it is combined with Midostaurin. |
Neratinib | Neratinib The serum concentration of Bendamustine can be increased when it is combined with Neratinib. |
Guselkumab Injection | Guselkumab Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Guselkumab. |
Enasidenib | Enasidenib The serum concentration of Bendamustine can be increased when it is combined with Enasidenib. |
Inotuzumab Ozogamicin Injection | Inotuzumab Ozogamicin Injection The serum concentration of Bendamustine can be increased when it is combined with Inotuzumab ozogamicin. |
Copanlisib Injection | Copanlisib Injection The serum concentration of Bendamustine can be increased when it is combined with Copanlisib. |
Betrixaban | Betrixaban The serum concentration of Bendamustine can be increased when it is combined with Betrixaban. |
Gemtuzumab Ozogamicin Injection | Gemtuzumab Ozogamicin Injection The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Bendamustine. |
Ertugliflozin | Ertugliflozin The serum concentration of Bendamustine can be increased when it is combined with Ertugliflozin. |
Apalutamide | Apalutamide The serum concentration of Bendamustine can be decreased when it is combined with Apalutamide. |
Penicillamine | Penicillamine The risk or severity of adverse effects can be increased when Penicillamine is combined with Bendamustine. |
Avatrombopag | Avatrombopag The serum concentration of Bendamustine can be increased when it is combined with Avatrombopag. |
Baricitinib | Baricitinib The risk or severity of adverse effects can be increased when Bendamustine is combined with Baricitinib. |
Lofexidine | Lofexidine The metabolism of Bendamustine can be decreased when combined with Lofexidine. |
Eliglustat | Eliglustat The serum concentration of Bendamustine can be increased when it is combined with Eliglustat. |
Binimetinib | Binimetinib The metabolism of Binimetinib can be decreased when combined with Bendamustine. |
Ivosidenib | Ivosidenib The serum concentration of Bendamustine can be increased when it is combined with Ivosidenib. |
Lusutrombopag | Lusutrombopag The serum concentration of Bendamustine can be increased when it is combined with Lusutrombopag. |
Elagolix | Elagolix The serum concentration of Bendamustine can be increased when it is combined with Elagolix. |
Cannabidiol | Cannabidiol The metabolism of Bendamustine can be decreased when combined with Cannabidiol. |
Dacomitinib | Dacomitinib The serum concentration of Bendamustine can be increased when it is combined with Dacomitinib. |
Duvelisib | Duvelisib The serum concentration of Bendamustine can be increased when it is combined with Duvelisib. |
Omadacycline | Omadacycline The serum concentration of Bendamustine can be increased when it is combined with Omadacycline. |
Sarecycline | Sarecycline The serum concentration of Bendamustine can be increased when it is combined with Sarecycline. |
Stiripentol | Stiripentol The metabolism of Bendamustine can be decreased when combined with Stiripentol. |
Talazoparib | Talazoparib The serum concentration of Bendamustine can be increased when it is combined with Talazoparib. |
Gilteritinib | Gilteritinib The serum concentration of Bendamustine can be increased when it is combined with Gilteritinib. |
Glasdegib | Glasdegib The serum concentration of Bendamustine can be increased when it is combined with Glasdegib. |
Larotrectinib | Larotrectinib The serum concentration of Bendamustine can be increased when it is combined with Larotrectinib. |
Methoxy Polyethylene Glycol-Epoetin Beta Injection | Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Bendamustine. |
Paclitaxel (with albumin) Injection | Paclitaxel (with albumin) Injection The risk or severity of adverse effects can be increased when Paclitaxel is combined with Bendamustine. |
Rifamycin | Rifamycin The serum concentration of Bendamustine can be increased when it is combined with Rifamycin. |
Ravulizumab-cwvz Injection | Ravulizumab-cwvz Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Ravulizumab. |
Emapalumab-lzsg Injection | Emapalumab-lzsg Injection The metabolism of Bendamustine can be increased when combined with Emapalumab. |
Siponimod | Siponimod The risk or severity of adverse effects can be increased when Bendamustine is combined with Siponimod. |
Acyclovir Ophthalmic | Acyclovir Ophthalmic The metabolism of Bendamustine can be decreased when combined with Acyclovir. |
Caplacizumab-yhdp Injection | Caplacizumab-yhdp Injection The risk or severity of bleeding can be increased when Caplacizumab is combined with Bendamustine. |
Erdafitinib | Erdafitinib The serum concentration of Bendamustine can be increased when it is combined with Erdafitinib. |
Risankizumab-rzaa Injection | Risankizumab-rzaa Injection The risk or severity of adverse effects can be increased when Bendamustine is combined with Risankizumab. |
Cladribine | Cladribine The risk or severity of adverse effects can be increased when Cladribine is combined with Bendamustine. |
Darolutamide | Darolutamide The serum concentration of Bendamustine can be increased when it is combined with Darolutamide. |
Triclabendazole | Triclabendazole The metabolism of Bendamustine can be decreased when combined with Triclabendazole. |
Entrectinib | Entrectinib The serum concentration of Bendamustine can be increased when it is combined with Entrectinib. |
Istradefylline | Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Bendamustine. |
Pitolisant | Pitolisant The metabolism of Bendamustine can be increased when combined with Pitolisant. |
Fedratinib | Fedratinib The serum concentration of Bendamustine can be increased when it is combined with Fedratinib. |
Lefamulin | Lefamulin The serum concentration of Bendamustine can be increased when it is combined with Lefamulin. |
Fosphenytoin Injection | Fosphenytoin Injection The metabolism of Bendamustine can be increased when combined with Fosphenytoin. |
Enfortumab vedotin-ejfv Injection | Enfortumab vedotin-ejfv Injection The serum concentration of Bendamustine can be increased when it is combined with Enfortumab vedotin. |
Lasmiditan | Lasmiditan The serum concentration of Bendamustine can be increased when it is combined with Lasmiditan. |
Ubrogepant | Ubrogepant The serum concentration of Bendamustine can be increased when it is combined with Ubrogepant. |
Tazemetostat | Tazemetostat The serum concentration of Bendamustine can be increased when it is combined with Tazemetostat. |
Ozanimod | Ozanimod The risk or severity of adverse effects can be increased when Bendamustine is combined with Ozanimod. |
Selumetinib | Selumetinib The metabolism of Selumetinib can be decreased when combined with Bendamustine. |
Rimegepant | Rimegepant The serum concentration of Bendamustine can be increased when it is combined with Rimegepant. |
Tucatinib | Tucatinib The serum concentration of Bendamustine can be increased when it is combined with Tucatinib. |
Remdesivir Injection | Remdesivir Injection The serum concentration of Bendamustine can be increased when it is combined with Remdesivir. |
Ripretinib | Ripretinib The serum concentration of Bendamustine can be increased when it is combined with Ripretinib. |
Capmatinib | Capmatinib The serum concentration of Bendamustine can be increased when it is combined with Capmatinib. |
Lemborexant | Lemborexant The serum concentration of Bendamustine can be increased when it is combined with Lemborexant. |
Fostemsavir | Fostemsavir The serum concentration of Bendamustine can be increased when it is combined with Fostemsavir. |
Belantamab Mafodotin-blmf Injection | Belantamab Mafodotin-blmf Injection The serum concentration of Bendamustine can be increased when it is combined with Belantamab mafodotin. |
Pralsetinib | Pralsetinib The serum concentration of Bendamustine can be increased when it is combined with Pralsetinib. |
Satralizumab-mwge Injection | Satralizumab-mwge Injection The serum concentration of Bendamustine can be decreased when it is combined with Satralizumab. |
Viloxazine | Viloxazine The metabolism of Bendamustine can be decreased when combined with Viloxazine. |
Theophylline | Theophylline The metabolism of Bendamustine can be decreased when combined with Theophylline. |
Indomethacin | Indomethacin The risk or severity of adverse effects can be increased when Indomethacin is combined with Bendamustine. |
Naproxen | Naproxen The metabolism of Bendamustine can be decreased when combined with Naproxen. |
Trazodone | Trazodone The serum concentration of Bendamustine can be decreased when it is combined with Trazodone. |
Hydroxyurea | Hydroxyurea The risk or severity of adverse effects can be increased when Hydroxyurea is combined with Bendamustine. |
Floxuridine | Floxuridine The risk or severity of adverse effects can be increased when Floxuridine is combined with Bendamustine. |
Methotrexate Injection | Methotrexate Injection The excretion of Methotrexate can be decreased when combined with Bendamustine. |
Primidone | Primidone The serum concentration of Bendamustine can be increased when it is combined with Primidone. |
Chlorpromazine | Chlorpromazine The metabolism of Bendamustine can be decreased when combined with Chlorpromazine. |
Carmustine | Carmustine The risk or severity of adverse effects can be increased when Carmustine is combined with Bendamustine. |
Tranylcypromine | Tranylcypromine The metabolism of Bendamustine can be decreased when combined with Tranylcypromine. |
Procarbazine | Procarbazine The risk or severity of adverse effects can be increased when Procarbazine is combined with Bendamustine. |
Thioguanine | Thioguanine The risk or severity of adverse effects can be increased when Tioguanine is combined with Bendamustine. |
Trifluoperazine | Trifluoperazine The metabolism of Bendamustine can be decreased when combined with Trifluoperazine. |
Bleomycin | Bleomycin The risk or severity of adverse effects can be increased when Bleomycin is combined with Bendamustine. |
Maprotiline | Maprotiline The metabolism of Bendamustine can be decreased when combined with Maprotiline. |
Orphenadrine | Orphenadrine The metabolism of Bendamustine can be decreased when combined with Orphenadrine. |
Perphenazine | Perphenazine The metabolism of Bendamustine can be decreased when combined with Perphenazine. |
Azathioprine | Azathioprine The risk or severity of adverse effects can be increased when Azathioprine is combined with Bendamustine. |
Sulfasalazine | Sulfasalazine The risk or severity of adverse effects can be increased when Sulfasalazine is combined with Bendamustine. |
Lomustine | Lomustine The risk or severity of adverse effects can be increased when Lomustine is combined with Bendamustine. |
Doxorubicin | Doxorubicin The risk or severity of adverse effects can be increased when Doxorubicin is combined with Bendamustine. |
Cytarabine | Cytarabine The risk or severity of adverse effects can be increased when Cytarabine is combined with Bendamustine. |
Mechlorethamine | Mechlorethamine The risk or severity of adverse effects can be increased when Mechlorethamine is combined with Bendamustine. |
Dactinomycin | Dactinomycin The risk or severity of adverse effects can be increased when Dactinomycin is combined with Bendamustine. |
Carbamazepine | Carbamazepine The serum concentration of Bendamustine can be increased when it is combined with Carbamazepine. |
Clonidine | Clonidine The metabolism of Bendamustine can be decreased when combined with Clonidine. |
Cimetidine | Cimetidine The metabolism of Bendamustine can be decreased when combined with Cimetidine. |
Warfarin | Warfarin The metabolism of Bendamustine can be decreased when combined with Warfarin. |
Loperamide | Loperamide The serum concentration of Bendamustine can be increased when it is combined with Loperamide. |
Daunorubicin | Daunorubicin The risk or severity of adverse effects can be increased when Daunorubicin is combined with Bendamustine. |
Griseofulvin | Griseofulvin The metabolism of Bendamustine can be increased when combined with Griseofulvin. |
Digoxin | Digoxin The serum concentration of Bendamustine can be increased when it is combined with Digoxin. |
Loxapine | Loxapine The serum concentration of Bendamustine can be increased when it is combined with Loxapine. |
Quinine | Quinine The serum concentration of Bendamustine can be increased when it is combined with Quinine. |
Triamterene | Triamterene The metabolism of Bendamustine can be decreased when combined with Triamterene. |
Sulfinpyrazone | Sulfinpyrazone The risk or severity of bleeding can be increased when Sulfinpyrazone is combined with Bendamustine. |
Chlorothiazide | Chlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Chlorothiazide is combined with Bendamustine. |
Secobarbital | Secobarbital The metabolism of Bendamustine can be increased when combined with Secobarbital. |
Amitriptyline | Amitriptyline The metabolism of Bendamustine can be decreased when combined with Amitriptyline. |
Imipramine | Imipramine The metabolism of Bendamustine can be decreased when combined with Imipramine. |
Quinidine | Quinidine The serum concentration of Bendamustine can be increased when it is combined with Quinidine. |
Isoniazid | Isoniazid The metabolism of Bendamustine can be decreased when combined with Isoniazid. |
Rifampin | Rifampin The serum concentration of Bendamustine can be increased when it is combined with Rifampicin. |
Disopyramide | Disopyramide The metabolism of Bendamustine can be decreased when combined with Disopyramide. |
Valproic Acid | Valproic Acid The metabolism of Bendamustine can be decreased when combined with Valproic acid. |
Tamoxifen | Tamoxifen The serum concentration of Bendamustine can be increased when it is combined with Tamoxifen. |
Mitomycin | Mitomycin The risk or severity of adverse effects can be increased when Mitomycin is combined with Bendamustine. |
Levothyroxine | Levothyroxine The serum concentration of Bendamustine can be decreased when it is combined with Levothyroxine. |
Methimazole | Methimazole The risk or severity of adverse effects can be increased when Methimazole is combined with Bendamustine. |
Propylthiouracil | Propylthiouracil The risk or severity of adverse effects can be increased when Propylthiouracil is combined with Bendamustine. |
Cyclobenzaprine | Cyclobenzaprine The metabolism of Bendamustine can be decreased when combined with Cyclobenzaprine. |
Methyclothiazide | Methyclothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Methyclothiazide is combined with Bendamustine. |
Hydrochlorothiazide | Hydrochlorothiazide The risk or severity of neutropenia and thrombocytopenia can be increased when Hydrochlorothiazide is combined with Bendamustine. |
Chlorzoxazone | Chlorzoxazone The metabolism of Bendamustine can be decreased when combined with Chlorzoxazone. |
Propranolol (Cardiovascular) | Propranolol (Cardiovascular) The metabolism of Bendamustine can be decreased when combined with Propranolol. |
Mercaptopurine | Mercaptopurine The risk or severity of adverse effects can be increased when Mercaptopurine is combined with Bendamustine. |
Allopurinol | Allopurinol The risk or severity of rash, hypersensitivity reaction, Stevens-Johnson syndrome, and Cutaneous drug reaction can be increased when Allopurinol is combined with Bendamustine. |
Clomiphene | Clomiphene The serum concentration of Bendamustine can be increased when it is combined with Clomifene. |
Fluorouracil Injection | Fluorouracil Injection The risk or severity of adverse effects can be increased when Fluorouracil is combined with Bendamustine. |
Colchicine | Colchicine The risk or severity of adverse effects can be increased when Colchicine is combined with Bendamustine. |
Dacarbazine | Dacarbazine The risk or severity of adverse effects can be increased when Dacarbazine is combined with Bendamustine. |
Bacillus Calmette-Guerin (BCG) Vaccine | Bacillus Calmette-Guerin (BCG) Vaccine The risk or severity of infection can be increased when Bacillus calmette-guerin substrain tice live antigen is combined with Bendamustine. |
Ketoconazole | Ketoconazole The serum concentration of Bendamustine can be increased when it is combined with Ketoconazole. |
Thiotepa Injection | Thiotepa Injection The risk or severity of adverse effects can be increased when Thiotepa is combined with Bendamustine. |
Vincristine Injection | Vincristine Injection The risk or severity of adverse effects can be increased when Vincristine is combined with Bendamustine. |
Dipyridamole | Dipyridamole The risk or severity of bleeding can be increased when Dipyridamole is combined with Bendamustine. |
Vinblastine | Vinblastine The risk or severity of adverse effects can be increased when Vinblastine is combined with Bendamustine. |
Thiothixene | Thiothixene The metabolism of Bendamustine can be decreased when combined with Thiothixene. |
Aspirin | Aspirin The risk or severity of bleeding can be increased when Acetylsalicylic acid is combined with Bendamustine. |
Chlorambucil | Chlorambucil The risk or severity of adverse effects can be increased when Chlorambucil is combined with Bendamustine. |
Nifedipine | Nifedipine The metabolism of Bendamustine can be decreased when combined with Nifedipine. |
Verapamil | Verapamil The serum concentration of Bendamustine can be increased when it is combined with Verapamil. |
Cisplatin Injection | Cisplatin Injection The risk or severity of adverse effects can be increased when Cisplatin is combined with Bendamustine. |
Streptozocin | Streptozocin The risk or severity of adverse effects can be increased when Streptozocin is combined with Bendamustine. |
Etoposide | Etoposide The risk or severity of adverse effects can be increased when Etoposide is combined with Bendamustine. |
Nafcillin Injection | Nafcillin Injection The metabolism of Bendamustine can be increased when combined with Nafcillin. |
Pentoxifylline | Pentoxifylline The metabolism of Bendamustine can be decreased when combined with Pentoxifylline. |
Gemfibrozil | Gemfibrozil The metabolism of Bendamustine can be decreased when combined with Gemfibrozil. |
Guanabenz | Guanabenz The metabolism of Bendamustine can be decreased when combined with Guanabenz. |
Pimozide | Pimozide The metabolism of Bendamustine can be decreased when combined with Pimozide. |
Amiodarone | Amiodarone The serum concentration of Bendamustine can be increased when it is combined with Amiodarone. |
Ciprofloxacin | Ciprofloxacin The serum concentration of Bendamustine can be increased when it is combined with Ciprofloxacin. |
Diclofenac | Diclofenac The metabolism of Bendamustine can be decreased when combined with Diclofenac. |
Fluoxetine | Fluoxetine The metabolism of Bendamustine can be decreased when combined with Fluoxetine. |
Interferon Alfa-2b Injection | Interferon Alfa-2b Injection The risk or severity of adverse effects can be increased when Interferon alfa-2b is combined with Bendamustine. |
Clozapine | Clozapine The risk or severity of neutropenia can be increased when Bendamustine is combined with Clozapine. |
Idarubicin | Idarubicin The risk or severity of adverse effects can be increased when Idarubicin is combined with Bendamustine. |
Ofloxacin | Ofloxacin The metabolism of Bendamustine can be decreased when combined with Ofloxacin. |
Fludarabine Injection | Fludarabine Injection The risk or severity of adverse effects can be increased when Fludarabine is combined with Bendamustine. |
Pentostatin Injection | Pentostatin Injection The risk or severity of adverse effects can be increased when Pentostatin is combined with Bendamustine. |
Clarithromycin | Clarithromycin The serum concentration of Bendamustine can be increased when it is combined with Clarithromycin. |
Nabumetone | Nabumetone The metabolism of Bendamustine can be decreased when combined with Nabumetone. |
Pravastatin | Pravastatin The serum concentration of Bendamustine can be increased when it is combined with Pravastatin. |
Simvastatin | Simvastatin The serum concentration of Bendamustine can be increased when it is combined with Simvastatin. |
Epoetin Alfa, Injection | Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Bendamustine. |
Teniposide Injection | Teniposide Injection The risk or severity of adverse effects can be increased when Teniposide is combined with Bendamustine. |
Itraconazole | Itraconazole The serum concentration of Bendamustine can be increased when it is combined with Itraconazole. |
Bisoprolol | Bisoprolol The serum concentration of Bendamustine can be increased when it is combined with Bisoprolol. |
Zolpidem | Zolpidem The metabolism of Bendamustine can be decreased when combined with Zolpidem. |
Omeprazole | Omeprazole The metabolism of Bendamustine can be increased when combined with Omeprazole. |
Fluvoxamine | Fluvoxamine The serum concentration of Bendamustine can be increased when it is combined with Fluvoxamine. |
Vinorelbine Injection | Vinorelbine Injection The risk or severity of adverse effects can be increased when Vinorelbine is combined with Bendamustine. |
Carboplatin Injection | Carboplatin Injection The risk or severity of adverse effects can be increased when Carboplatin is combined with Bendamustine. |
Ifosfamide Injection | Ifosfamide Injection The risk or severity of adverse effects can be increased when Ifosfamide is combined with Bendamustine. |
Pegaspargase Injection | Pegaspargase Injection The risk or severity of adverse effects can be increased when Pegaspargase is combined with Bendamustine. |
Ticlopidine | Ticlopidine The metabolism of Bendamustine can be decreased when combined with Ticlopidine. |
Saquinavir | Saquinavir The serum concentration of Bendamustine can be increased when it is combined with Saquinavir. |
Dalteparin Injection | Dalteparin Injection The risk or severity of bleeding can be increased when Dalteparin is combined with Bendamustine. |
Riluzole | Riluzole The metabolism of Bendamustine can be decreased when combined with Riluzole. |
Gemcitabine Injection | Gemcitabine Injection The risk or severity of adverse effects can be increased when Gemcitabine is combined with Bendamustine. |
Ritonavir | Ritonavir The serum concentration of Bendamustine can be increased when it is combined with Ritonavir. |
Docetaxel Injection | Docetaxel Injection The risk or severity of adverse effects can be increased when Docetaxel is combined with Bendamustine. |
Clomipramine | Clomipramine The metabolism of Bendamustine can be decreased when combined with Clomipramine. |
Zafirlukast | Zafirlukast The serum concentration of Bendamustine can be increased when it is combined with Zafirlukast. |
Mirtazapine | Mirtazapine The metabolism of Bendamustine can be decreased when combined with Mirtazapine. |
Zileuton | Zileuton The metabolism of Bendamustine can be decreased when combined with Zileuton. |
Insulin Lispro Injection | Insulin Lispro Injection The metabolism of Bendamustine can be increased when combined with Insulin lispro. |
Fexofenadine | Fexofenadine The serum concentration of Bendamustine can be increased when it is combined with Fexofenadine. |
Carvedilol | Carvedilol The serum concentration of Bendamustine can be increased when it is combined with Carvedilol. |
Flutamide | Flutamide The metabolism of Bendamustine can be decreased when combined with Flutamide. |
Selegiline | Selegiline The metabolism of Bendamustine can be decreased when combined with Selegiline. |
Propafenone | Propafenone The serum concentration of Bendamustine can be increased when it is combined with Propafenone. |
Paroxetine | Paroxetine The metabolism of Bendamustine can be decreased when combined with Paroxetine. |
Citalopram | Citalopram The metabolism of Bendamustine can be decreased when combined with Citalopram. |
Capecitabine | Capecitabine The risk or severity of adverse effects can be increased when Capecitabine is combined with Bendamustine. |
Efavirenz | Efavirenz The metabolism of Bendamustine can be decreased when combined with Efavirenz. |
Sildenafil | Sildenafil The serum concentration of Bendamustine can be increased when it is combined with Sildenafil. |
Trastuzumab Injection | Trastuzumab Injection Trastuzumab may increase the neutropenic activities of Bendamustine. |
Rosiglitazone | Rosiglitazone The metabolism of Bendamustine can be decreased when combined with Rosiglitazone. |
Thalidomide | Thalidomide The risk or severity of adverse effects can be increased when Thalidomide is combined with Bendamustine. |
Rabeprazole | Rabeprazole The metabolism of Bendamustine can be increased when combined with Rabeprazole. |
Terbinafine | Terbinafine The metabolism of Bendamustine can be decreased when combined with Terbinafine. |
Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists