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basic care nasal oxymetazoline hydrochloride .05 g/100mL Spray — NDC 72288-0304-10 package photo

basic care nasal oxymetazoline hydrochloride .05 g/100mL Spray

by Amazon.com Services LLC · 1 BOTTLE, SPRAY in 1 CARTON (72288-304-10) / 30 mL in 1 BOTTLE, SPRAY
NDC 72288-0304-10
🏷️ FDA NDC (as labeled) 72288-304-10 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

⚠️
Other active recalls for Oxymetazoline Hydrochloride (different manufacturers) — 3 · tap to view
These affect other manufacturers’ products for the same ingredient — not necessarily the exact NDC on this page.
Class II · Dec 28, 2023 — CGMP Deviations: Firm reported possible microbial contamination in the purified water used in the manufacturing of the products. No contamination was found in the final products. (Seaway Pharma Inc.) · FDA recall D-0216-2024
Class II · Dec 28, 2023 — CGMP Deviations: Firm reported possible microbial contamination in the purified water used in the manufacturing of the products. No contamination was found in the final products. (Seaway Pharma Inc.) · FDA recall D-0214-2024
Class II · Dec 28, 2023 — CGMP Deviations: Firm reported possible microbial contamination in the purified water used in the manufacturing of the products. No contamination was found in the final products. (Seaway Pharma Inc.) · FDA recall D-0217-2024
Each entry is an official FDA enforcement report — look up any recall number in the FDA recall database ↗

🆔 Identity & classification

FDA NDC (as labeled) 72288-304-10
Product NDC 72288-304
11-digit billing NDC 72288030410
RxCUI 1000990
UNII K89MJ0S5VY
Application # M012
SPL Set ID a154e500-2b45-4242-a26c-9530849f99df
Established class (EPC) Vasoconstrictor
Physiologic effect Increased Sympathetic Activity; Vasoconstriction
Chemical class Imidazolines
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2021-07-09
Route NASAL
Dosage form SPRAY
Substance OXYMETAZOLINE HYDROCHLORIDE
Why two NDCs? The FDA registers this code as 72288-304-10 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 72288-0304-10. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏷️ RxNorm drug class

This medicine belongs to the Vasoconstrictor class.

Pharmacologic class Vasoconstrictor
Drug family (ATC) Other dermatologicals, Sympathomimetics, plain, Sympathomimetics used as decongestants
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

🏭 Manufacturer & labeler

LabelerAmazon.com Services LLC
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code72288
First marketedJul 2021
Product typeHuman Otc Drug
Portfolio331 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

📖 What it is MedlinePlus · NLM

Oxymetazoline nasal spray is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Oxymetazoline nasal spray should not be used to treat children younger than 6 years of age unless it is recommended by a doctor. Children 6 to 12 years of age should use oxymetazoline nasal spray carefully and under adult supervision. Oxymetazoline is in a class of medications called nasal decongestants. It works by narrowing the blood vessels in the nasal passages.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • It's really important to stick to 3 days maximum with oxymetazoline nasal spray. Using it longer can actually make your congestion worse — this is called rebound congestion, where...
  • Can I use the nasal spray for more than a few days if my congestion keeps coming back?
  • Upneeq doesn't fix the underlying cause of the drooping — it temporarily lifts the lid by stimulating a small muscle in your eyelid. The effect kicks in around 2 hours after you us...
  • What exactly does Upneeq do for a drooping eyelid — will it fix the problem permanently?
📖 Read our full Oxymetazoline guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

💊 What it looks like

Color White
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII F5UM2KM3W7
    Benzalkonium chloride is a chemical compound that works as a preservative and antimicrobial agent in medications. It prevents bacterial and fungal growth in liquid formulations to keep the product safe during storage and use.
  • UNII LKG8494WBH
    Benzyl alcohol is a clear liquid used as a preservative and solvent in medicines. It helps prevent bacterial and fungal growth and dissolves other ingredients to create uniform liquid formulations.
  • UNII 7FLD91C86K
    Edetate disodium is a chemical compound that binds and removes certain metal ions. In medicines, it acts as a preservative and stabilizer by preventing metals like calcium from interfering with the product's shelf life and consistency.
  • UNII 3WJQ0SDW1A
    Polyethylene glycol is a synthetic liquid or solid polymer used in medicines as a solvent, lubricant, and humectant. It helps dissolve active ingredients, reduces friction during manufacturing, and retains moisture in the final product.
  • UNII FZ989GH94E
    Povidone is a synthetic polymer made from a plastic-like material. It acts as a binder to hold tablet ingredients together and as a disintegrant to help the tablet break apart in your stomach so the medicine can be absorbed.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII GR686LBA74
    Sodium phosphate, dibasic is a salt derived from phosphoric acid. It acts as a buffer to help maintain the medicine's pH balance and may serve as a binder or filler in tablets and capsules.
  • UNII 3980JIH2SW
    A salt form of phosphoric acid that acts as a buffer and pH adjuster in medicines. It helps keep the product at the correct acidity level for stability and effectiveness.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

9 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesbenzalkonium chloride solution, benzyl alcohol, dibasic sodium phosphate, edetate disodium, monobasic sodium phosphate, polyethylene glycol, povidone, propylene glycol, purified water

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Sense Nasal .5 mg/mL 00113-0304-10 L. 1 bottle $0.076 — Availability likely —
good sense nasal .05 g/100mL 00113-0388-10 L. 1 bottle $0.076 — Availability likely —
Major Nasal Decongestant .5 mg/mL 00904-7427-30 Major 1 bottle $0.076 — Availability likely —
12 Hour Original Nasal Decongestant 50 mg/100mL 11527-0140-55 Sheffield 1 bottle $0.076 — Availability likely —
Good Neighbor Pharmacy Nasal .05 g/100mL 24385-0352-10 Amerisource 1 bottle $0.076 — Availability likely —
oxymetazoline hcl .05 g/100mL 45802-0410-59 Padagis 1 bottle $0.076 — Availability likely —
good neighbor pharmacy nasal .05 g/100mL 46122-0165-10 Amerisource 1 bottle $0.076 — Availability likely —
foster and thrive nasal .05 g/100mL 70677-1037-01 Strategic 1 bottle $0.076 — Availability likely —
Quality Choice Nasal .05 g/100mL 83324-0238-01 CHAIN 1 bottle $0.076 — Availability likely —
Sunmark Nasal Original .05 mg/100mL 49348-0028-27 Strategic 1 bottle $0.076 — Discontinued —
Good Neighbor No Drip Nasal Mist Extra Moisturizing .05 g/100mL 46122-0792-35 AMERISOURCE 1 bottle $0.105 — Availability likely —
GOOD NEIGHBOR PHARMACY No Drip Nasal Mist .05 g/100mL 46122-0796-35 AMERISOURCE 1 bottle $0.105 — Availability likely —
Leader Nasal Decongestant .5 mg/mL 70000-0665-01 Cardinal 1 bottle $0.105 — Availability likely —
foster and thrive nasal .05 g/100mL 70677-1039-01 Strategic 1 bottle $0.105 — Availability likely —
Quality Choicel Nasal Mist Extra Moisturizing .05 g/100mL 83324-0211-01 CHAIN 1 bottle $0.105 — Availability likely —
Quality Choice Nasal Mist Severe Congestion .05 g/100mL 83324-0274-01 CHAIN 1 bottle $0.105 — Availability likely —
Major Nasal Decongestant .5 mg/mL 00904-7435-35 Major 1 bottle $0.122 — Availability likely —
Leader Nasal Decongestant .5 mg/mL 70000-0676-01 Cardinal 1 bottle $0.122 — Availability likely —
Theraflu Severe Congestion Relief Cooling Nasal Mist .5 mg/mL 00067-0109-01 Haleon 1 bottle — — FDA listed —
Theraflu Severe Congestion Relief Nasal Mist .5 mg/mL 00067-0110-01 Haleon 1 bottle — — FDA listed —
good sense nasal .05 g/100mL 00113-6200-10 L. 1 bottle — — FDA listed —
Anefrin Nasal Original .05 g/100mL 00363-0304-10 Walgreen 1 bottle — — FDA listed —
No Drip Nasal Mist 50 mg/mL 00363-2303-52 Walgreens 1 bottle — — FDA listed —
Severe Sinus Relief Mist 50 mg/100mL 00363-2305-52 Walgreens 1 bottle — — FDA listed —
No Drip Nasal Mist 50 mg/100mL 00363-2307-52 Walgreens 1 bottle — — FDA listed —
No Drip Severe Anefrin Nasal 50 mg/100mL 00363-2350-52 Walgreens 1 bottle — — FDA listed —
Walgreens Moisturizing Ultra Fine Mist with Aloe 50 mg/100mL 00363-2355-15 Walgreens 1 bottle — — FDA listed —
Walgreen .05 g/100mL 00363-7151-15 WALGREENS 1 bottle — — FDA listed —
Zicam Extreme Congestion Relief .5 mg/mL 10237-0464-15 Church 1 bottle — — FDA listed —
Zicam Intense Sinus Relief .5 mg/mL 10237-0471-15 Church 1 bottle — — FDA listed —
Afrin NoDrip Allergy Sinus Night .5 mg/mL 11523-0034-01 Bayer 15 ml — — FDA listed —
Afrin Allergy Sinus Nasal .5 g/100mL 11523-0073-01 Bayer 1 bottle — — FDA listed —
Children Afrin No Drip Extra Moisturizing Stuffy Nose Pump Mist Stuffy Nose Pump Mist .05 g/100mL 11523-0090-01 Bayer 1 bottle — — FDA listed —
Afrin No Drip Pump Mist Bundle Pack 11523-0147-01 Bayer 1 kit — — FDA listed —
Afrin Original Pump Mist .05 g/100mL 11523-1159-01 Bayer 1 bottle — — FDA listed —
Afrin Original .05 g/100mL 11523-1167-01 Bayer 6 ml — — FDA listed —
Afrin Original Nasal .05 g/100mL 11523-1168-06 Bayer 6 bottles — — FDA listed —
Afrin No Drip Severe Congestion .05 g/100mL 11523-1350-01 Bayer 1 bottle — — FDA listed —
Afrin No Drip Extra Moisturizing .05 g/100mL 11523-1783-01 Bayer 1 bottle — — FDA listed —
Afrin No Drip Original Pump Mist .05 g/100mL 11523-3142-01 Bayer 1 bottle — — FDA listed —
Afrin No-Drip Allergy Sinus .05 mg/mL 11523-3220-01 Bayer 1 bottle — — FDA listed —
Afrin Severe Congestion .05 g/100mL 11523-7020-01 Bayer 1 bottle — — FDA listed —
Up and up nasal .05 g/100mL 11673-0304-10 Target 1 bottle — — FDA listed —
nasal .05 g/100mL 11822-0304-01 Rite 1 bottle — — FDA listed —
nasal .05 g/100mL 11822-6319-01 Rite 1 bottle — — FDA listed —
nasal .05 g/100mL 11822-6378-01 Rite 1 bottle — — FDA listed —
nasal .05 g/100mL 11822-6623-01 Rite 1 bottle — — FDA listed —
SinuFrin NeilMed 7.5 mg/15mL 13709-0231-04 NeilMed 15 ml — — FDA listed —
SinuFrin Plus NeilMed 7.5 mg/15mL 13709-0232-05 NeilMed 15 ml — — FDA listed —
No Drip 15 mg/30mL 13709-0315-01 NeilMed 1 bottle — — FDA listed —
Sinufrin Decongestant 7.5 mg/15mL 13709-0355-01 NeilMed 1 bottle — — FDA listed —
Sinufrin Plus No Drip Decongestant 7.5 mg/15mL 13709-0356-01 NeilMed 1 bottle — — FDA listed —
nasal decongestant .05 g/100mL 21130-0420-10 Safeway 1 bottle — — FDA listed —
Signature Care Nasal Decongestant .05 g/100mL 21130-0589-10 Safeway 1 bottle — — FDA listed —
Signature Care Nasal Decongestant .05 g/100mL 21130-0801-10 Safeway 1 bottle — — FDA listed —
nasal decongestant .05 g/100mL 21130-0807-10 Safeway 1 bottle — — FDA listed —
signature care nasal decongestant .05 g/100mL 21130-0813-10 Safeway 1 bottle — — FDA listed —
nasal decongestant .05 g/100mL 21130-0837-10 Safeway 1 bottle — — FDA listed —
Signature Care Original .05 g/100mL 21130-0956-28 SAFEWAY, 1 bottle — — FDA listed —
Xlear Nasal Decongestant .0005 g/g 27017-0018-01 Xlear 1 g — — FDA listed —
Nasal .05 g/100mL 30142-0304-10 Kroger 1 bottle — — FDA listed —
nasal .05 g/100mL 30142-0388-10 Kroger 1 bottle — — FDA listed —
No Drip Nasal Mist .05 g/100mL 30142-0606-10 Kroger 1 bottle — — FDA listed —
Kroger No Drip .05 mg/mL 30142-0718-30 KROGER 1 bottle — — FDA listed —
Topcare Nasal .05 g/100mL 36800-0304-10 Topco 1 bottle — — FDA listed —
Topcare Nasal .05 g/100mL 36800-0388-10 Topco 1 bottle — — FDA listed —
topcare sinus nasal .05 g/100mL 36800-0711-10 Topco 1 bottle — — FDA listed —
Topcare Nasal .05 g/100mL 36800-0907-10 Topco 1 bottle — — FDA listed —
nasal .05 g/100mL 37808-0004-10 H 1 bottle — — FDA listed —
nasal .05 g/100mL 37808-0752-10 H 1 bottle — — FDA listed —
Nasal .05 g/100mL 37835-0995-34 Bi-Mart 1 bottle — — FDA listed —
Oxymetazoline Hydrochloride .05 g/100mL 37835-0996-01 Bi-Mart 1 bottle — — FDA listed —
equaline nasal .05 g/100mL 41163-0061-10 United 1 bottle — — FDA listed —
Equaline Nasal .05 g/100mL 41163-0343-10 United 1 bottle — — FDA listed —
equaline nasal .05 g/100mL 41163-0703-10 United 1 bottle — — FDA listed —
KROGER No Drip Nasal Mist Severe Congestion .05 g/100mL 41226-0718-30 KROGER 1 bottle — — FDA listed —
nasal 12 hour .05 g/100mL 41250-0304-10 Meijer 1 bottle — — FDA listed —
nasal .05 g/100mL 41250-0388-10 Meijer 1 bottle — — FDA listed —
Meijer Original .05 g/100mL 41250-0457-01 MEIJER 1 bottle — — FDA listed —
nasal .05 g/100mL 41250-0989-10 Meijer 1 bottle — — FDA listed —
Publix Maximum Strength .05 g/100mL 41415-0715-30 PUBLIX 1 bottle — — FDA listed —
Publix .05 g/100mL 41415-0716-30 PUBLIX 1 bottle — — FDA listed —
Publix Extra Moisturizing .05 g/100mL 41415-0720-30 PUBLIX 1 bottle — — FDA listed —
CareOne Severe Congestion Nasal .05 g/100mL 41520-0108-10 American 1 bottle — — FDA listed —
care one nasal original .05 g/100mL 41520-0304-10 American 1 bottle — — FDA listed —
Care One Nasal .05 g/100mL 41520-0388-10 American 1 bottle — — Discontinued —
nasal original .05 g/100mL 42507-0304-10 HyVee 1 bottle — — FDA listed —
nasal .05 g/100mL 42507-0388-10 HyVee 1 bottle — — FDA listed —
nasal .05 g/100mL 42507-0796-10 HyVee 1 bottle — — FDA listed —
AVON HeXashield Congestion Relief Original .05 g/mL 43136-0105-01 Tai 1 bottle — — FDA listed —
equate nasal original .05 g/100mL 49035-0304-10 Wal-Mart 1 bottle — — FDA listed —
Equate Nasal .05 g/100mL 49035-0388-10 Wal-Mart 1 bottle — — FDA listed —
No Drip Nasal Mist Nasal Decongestant Severe Congestion .05 g/100mL 49035-0991-30 Wal-Mart 1 bottle — — FDA listed —
Tukol Max Action .5 mg/mL 50066-0518-05 Genomma 1 bottle — — FDA listed —
oxymetazoline hcl .05 g/100mL 50090-4308-00 A-S 1 bottle — — FDA listed —
nasal decongestant .05 g/100mL 50090-5281-00 A-S 1 bottle — — FDA listed —
Good Sense Nasal .5 mg/mL 50090-7409-00 A-S 1 bottle — — FDA listed —
Major Nasal Decongestant .5 mg/mL 50090-7630-00 A-S 1 bottle — — FDA listed —
Afrin Original Nasal .05 g/100mL 50269-0017-06 JC 6 bottles — — FDA listed —
SUDAFED OM Sinus Severe No Drip Nasal Mist 50 mg/100mL 50580-0364-01 Kenvue 1 bottle — — FDA listed —
SUDAFED OM Sinus Severe No Drip Nasal Mist with Cooling Menthol 50 mg/100mL 50580-0368-01 Kenvue 1 bottle — — FDA listed —
SUDAFED OM Sinus Severe Original 50 mg/100mL 50580-0787-01 Kenvue 1 bottle — — FDA listed —
CVS Original Nasal Mist .05 g/100mL 51316-0140-30 CVS 1 bottle — — FDA listed —
No Drip Nasal Mist 50 mg/100mL 51316-0312-32 CVS 1 bottle — — FDA listed —
Oxymetazoline Hydrochloride 12-Hour .05 g/100mL 51672-2030-03 Sun 1 bottle — — FDA listed —
Discount Drug Mart Original Nasal .05 g/100mL 53943-0715-30 DISCOUNT 1 bottle — — FDA listed —
Discount Drug Mart Maximum Strength Nasal .05 g/100mL 53943-0716-30 DISCOUNT 1 bottle — — FDA listed —
Discount Drug Mart Severe Congestion Nasal .05 g/100mL 53943-0718-30 DISCOUNT 1 bottle — — FDA listed —
Discount drug mart Extra Moisturizing .05 g/100mL 53943-0720-30 DISCOUNT 1 bottle — — FDA listed —
Discount Drug Mart Severe Nasal .05 g/100mL 53943-0726-30 DISCOUNT 1 bottle — — FDA listed —
Exchange Select Nasal .05 g/100mL 55301-0304-10 Army 1 bottle — — FDA listed —
Exchange Select Nasal .05 g/100mL 55301-0388-10 Army 1 bottle — — FDA listed —
Family Dollar .05 g/100mL 55319-0715-30 FAMILY 1 bottle — — FDA listed —
No Drip Nasal Mist .05 g/100mL 55319-0716-30 FAMILY 1 bottle — — FDA listed —
Family Dollar Ultra Fine Mist Sinus Relief .05 g/100mL 55319-0726-30 FAMILY 1 bottle — — FDA listed —
Family Wellness Oxymetazoline Sinus Severe 50 mg/100mL 55319-0827-30 FAMILY 1 bottle — — FDA listed —
Family Wellness Oxymetazoline No Drip 50 mg/100mL 55319-0983-28 FAMILY 1 bottle — — FDA listed —
Family Wellness Oxymetazoline 50 mg/100mL 55319-0985-28 FAMILY 1 bottle — — FDA listed —
dg health nasal original .05 g/100mL 55910-0304-10 Dolgencorp, 1 bottle — — FDA listed —
DG Health Nasal .05 g/100mL 55910-0511-10 Dolgencorp, 1 bottle — — FDA listed —
dg health nasal .05 g/100mL 55910-0623-10 Dolgencorp, 1 bottle — — FDA listed —
Ultra Fine Mist Sinus Relief .05 g/100mL 55910-0627-30 DOLGENCORP, 1 bottle — — FDA listed —
DG health sinus severe .05 g/100mL 55910-0696-10 Dolgencorp, 1 bottle — — FDA listed —
Giltuss Severe Sinus .05 g/100mL 58552-0142-15 Gil 1 bottle — — FDA listed —
nasal .05 g/100mL 59640-0388-10 H 1 bottle — — FDA listed —
nasal mist .05 g/100mL 59779-0388-10 CVS 1 bottle — — FDA listed —
CVS Health Sinus Relief .0005 g/mL 59779-0787-15 CVS 1 bottle — — FDA listed —
Nostrilla .05 mg/100mL 63736-0730-01 Insight 1 bottle — — FDA listed —
MUCINEX SINUS-MAX SEVERE CONGESTION RELIEF SINUS and ALLERGY .05 g/100mL 63824-0120-11 Reckitt 1 bottle — — FDA listed —
MUCINEX SINUS-MAX SEVERE NASAL CONGESTION RELIEF CLEAR and COOL NASAL .05 g/100mL 63824-0129-17 Reckitt 1 bottle — — FDA listed —
MUCINEX Childrens Stuffy Nose .05 g/100mL 63824-0961-22 Reckitt 1 bottle — — FDA listed —
Oxymetazoline Hydrochloride .05 g/100mL 63868-0605-01 CHAIN 30 ml — — FDA listed —
Oxymetazoline Hydrochloride .05 g/100mL 63868-0607-01 CHAIN 30 ml — — FDA listed —
Oxymetazoline Hydrochloride .05 g/100mL 63868-0676-01 CHAIN 30 ml — — FDA listed —
Quality Choice Maximum Strength .05 g/100mL 63868-0698-30 CHAIN 1 bottle — — FDA listed —
Quality Choice .05 g/100mL 63868-0699-22 CHAIN 1 bottle — — FDA listed —
Best Choice Maximum Strength .05 g/100mL 63941-0715-30 BEST 1 bottle — — FDA listed —
Best Choice .05 g/100mL 63941-0716-30 BEST 1 bottle — — FDA listed —
Best Choice Maximum Strength .05 g/100mL 63941-0718-30 BEST 1 bottle — — FDA listed —
Best Choice .05 g/100mL 63941-0720-30 BEST 1 bottle — — FDA listed —
Best Choice Ultra Fine Mist .05 g/100mL 63941-0726-30 BEST 1 bottle — — FDA listed —
Vicks Sinex SEVERE CONGESTION .0005 g/mL 64336-0002-01 Procter 1 bottle — — FDA listed —
VICKS SINEX SEVERE CONGESTION ORIGINAL Ultra Fine Mist .0005 g/mL 64336-0003-01 Procter 1 bottle — — FDA listed —
Vicks Sinex SEVERE CONGESTION MOISTURIZING ULTRA FINE MIST .0005 g/mL 64336-0004-01 Procter 1 bottle — — FDA listed —
Vicks SINEX SEVERE CONGESTION VapoCOOL ULTRA FINE MIST .0005 g/mL 64336-0005-01 Procter 1 bottle — — FDA listed —
Vicks Sinex Severe Original .0005095 g/mL 64336-0170-01 Procter 1 bottle — — FDA listed —
Vicks Sinex SEVERE ORIGINAL ULTRA FINE MIST .0005095 g/mL 64336-0171-01 Procter 1 bottle — — FDA listed —
Vicks Sinex SEVERE VapoCOOL ULTRA FINE MIST .0005095 g/mL 64336-0173-01 Procter 1 bottle — — FDA listed —
Family Care Nasal Relief .05 g/100mL 65923-0570-15 United 1 bottle — — FDA listed —
Nasal Spray, Circle K .05 g/100mL 66715-5460-04 Lil' 1 bottle — — FDA listed —
Nasal Spray, 1oz, 24/7 Life by 7-Eleven .05 g/100mL 66715-5526-04 Lil' 1 bottle — — FDA listed —
Circle K Congestion Relief .05 g/100mL 66715-5560-04 Lil' 1 bottle — — FDA listed —
Nasal Spray, 24-7 for Life .05 g/100mL 66715-5626-04 Lil' 1 bottle — — FDA listed —
Afrin Original .05 g/100mL 66715-5880-00 Lil' 1 bottle — — FDA listed —
Nasal Spray, Lil Drug Store .05 g/100mL 66715-6760-04 Lil' 1 bottle — — FDA listed —
Congestion Relief Lil Drug Store Products .05 g/100mL 66715-6860-04 Lil' 1 bottle — — FDA listed —
Afrin Original .05 g/100mL 66715-7016-03 Lil' 1 bottle — — FDA listed —
Extra Moisturizing Nasal Pump Mist Anti Drip .05 g/100mL 67091-0324-30 WinCo 1 bottle — — FDA listed —
Severe Congestion Nasal Anti-Drip Nasal Decongestant .05 g/100mL 67091-0325-30 WinCo 1 bottle — — FDA listed —
ORIGINAL Nasal PUMP MIST No Drip .05 g/100mL 67091-0326-30 WinCo 1 bottle — — FDA listed —
12 Hour Nasal Decongestant Extra Moisturizing 50 mg/100mL 67091-0377-08 WinCo 1 bottle — — FDA listed —
12 Hour Original Nasal Decongestant 50 mg/100mL 67091-0378-08 WinCo 1 bottle — — FDA listed —
Afrin .05 g/100mL 67751-0185-01 Navajo 15 ml — — FDA listed —
oxymetazoline hydrochloride .05 g/100mL 68071-3422-01 NuCare 1 bottle — — FDA listed —
Major Nasal Decongestant .5 mg/mL 68071-3858-03 NuCare 1 bottle — — FDA listed —
foster and thrive nasal .05 g/100mL 68071-3984-03 NuCare 1 bottle — — FDA listed —
Oxymetazoline hydrochloride .05 g/100mL 68210-5056-01 Prodose, 1 bottle — — FDA listed —
berkley and jensen nasal .05 g/100mL 68391-0721-16 BJWC 2 bottles — — FDA listed —
good neighbor pharmacy nasal .05 g/100mL 68788-4121-03 Preferred 1 bottle — — FDA listed —
Major Nasal Decongestant .5 mg/mL 68788-8744-03 Preferred 1 bottle — — FDA listed —
Marc Glassman Maximum Strength .05 g/100mL 68998-0715-30 MARC 1 bottle — — FDA listed —
Oxymethazoline HCL .05 mg 69618-0050-51 Reliable 1 bottle — — FDA listed —
Reliable-1 Anti Drip Pump Mist .05 g/100mL 69618-0716-30 Reliable 1 bottle — — FDA listed —
No Drip Nasal Mist 50 mg/100mL 69842-0312-51 CVS 1 bottle — — FDA listed —
No Drip Severe Nasal Mist 50 mg/100mL 69842-0315-30 CVS 1 bottle — — FDA listed —
Maximum Strength Nasal Decongestant 50 mg/100mL 69842-0316-51 CVS 1 bottle — — FDA listed —
Nasal .05 g/100mL 69842-0547-10 CVS 1 bottle — — FDA listed —
CVS Health .05 g/100mL 69842-0575-15 CVS 1 bottle — — FDA listed —
CVS Severe Nasal Congestion Relief Clear and Cool .05 g/100mL 69842-0614-22 CVS 1 bottle — — FDA listed —
CVS Health Sinus .05 g/100mL 69842-0715-15 CVS 1 bottle — — FDA listed —
CVS Health Ultra Fine Mist .05 g/100mL 69842-0726-16 CVS 1 bottle — — FDA listed —
CVS Health No Drip .05 g/100mL 69842-0781-15 CVS 1 bottle — — FDA listed —
CVS Health No Drip .05 g/100mL 69842-0815-15 CVS 1 bottle — — FDA listed —
Oxymethazoline HCL .05 mg 71205-0383-30 Proficient 1 bottle — — FDA listed —
basic care nasal .05 g/100mLthis 72288-0304-10 Amazon.com 1 bottle — — FDA listed —
basic care no drip nasal .05 g/100mL 72288-0388-10 Amazon.com 1 bottle — — FDA listed —
basic care no drip nasal .05 g/100mL 72288-0703-10 Amazon.com 1 bottle — — FDA listed —
Mucinex Sinus Max Clear and Cool Severe Congestion .05 g/100mL 72854-0218-11 Reckitt 1 bottle — — FDA listed —
Mucinex Sinus Max Sinus Pressure Severe Congestion .05 g/100mL 72854-0219-11 Reckitt 1 bottle — — FDA listed —
No More Nosebleed .05 g/100mL 73169-0001-01 DR. 1 bottle — — FDA listed —
Severe Nasal .05 g/100mL 73492-0715-15 ALAINA 1 bottle — — FDA listed —
nasal .05 g/100mL 79481-0425-00 Meijer, 1 bottle — — FDA listed —
Equate .05 g/100mL 79903-0195-15 Walmart 1 bottle — — FDA listed —
Equate .05 g/100mL 79903-0346-05 Walmart 1 bottle — — FDA listed —
Dristan 12 hr .5 mg/mL 80070-0400-05 Foundation 1 bottle — — FDA listed —
Up And Up No Drip Nasal .05 g/100mL 82442-0388-10 Target 1 bottle — — FDA listed —
Sinus Severe Ultra Fine Mist .5 mg/mL 82706-0026-01 VIVUNT 1 bottle — — FDA listed —
AXIV Sinus Severe Ultra Fine Mist .5 mg/mL 82706-0030-01 VIVUNT 1 bottle — — FDA listed —
AXIV Sinus OVERNIGHT .5 mg/mL 82706-0034-01 VIVUNT 1 bottle — — FDA listed —
QUALITY CHOICE No Drip Nasal Mist .05 g/100mL 83324-0142-01 QUALITY 1 bottle — — FDA listed —
foster and thrive nasal .05 g/100mL 85766-0087-30 Sportpharm 1 bottle — — FDA listed —
Good Sense Nasal .5 mg/mL 85766-0164-30 Sportpharm 1 bottle — — FDA listed —
Sine Aid PEAK MISERY .05 g/100mL 62372-0100-30 Infirst 30 ml — — FDA listed —
Nasal .05 g/100mL 72288-0859-10 Amazon.com 1 bottle — — FDA listed —
Oxymetazoline hydrochloride nasal solution .05 g/100mL 87265-0049-01 ACCENT 1 bottle — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2021
On the market since
Jul 2021
📍
2026
Currently FDA-listed
5 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
72288-0304-10 You're viewing this 1 BOTTLE, SPRAY in 1 CARTON (72288-304-10) / 30 mL in 1 BOTTLE, SPRAY 2021-07-09 Active

🧭 About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 72288-304-10, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 72288-0304-10, written without dashes as 72288030410. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 72288-0304-10, the first segment (72288) is the labeler code FDA assigned to Amazon.com Services LLC; the middle segment (0304) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (10) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Amazon.com Services LLC. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Amazon.com Services LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 36 words ▾

Uses • temporarily relieves nasal congestion due to: • common cold • hay fever • upper respiratory allergies • temporarily relieves sinus congestion and pressure • shrinks swollen nasal membranes so you can breathe more freely

⏱️ Dosage and Administration 84 words ▾

Directions • adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. Do not exceed 2 doses in any 24-hour period. • children under 6 years of age: ask a doctor To Use: Push firmly down on cap and turn counter clockwise. To spray, squeeze bottle quickly and firmly. Do not tilt head backward while spraying. Wipe nozzle clean after use. Secure cap after use.

⚠️ Warnings 134 words ▾

Warnings Ask a doctor before use if you have • heart disease • high blood pressure • thyroid disease • diabetes • trouble urinating due to an enlarged prostate gland When using this product • do not use more than directed • do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen. • temporary discomfort such as burning, stinging, sneezing or an increase in nasal discharge may occur • use of this container by more than one person may spread infection Stop use and ask a doctor if symptoms persist If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222).

📦 Storage and Handling 16 words ▾

Other information • store at 20-25°C (68-77°F) • retain carton for future reference on full labeling

🧪 Active Ingredient 5 words ▾

Active ingredient Oxymetazoline hydrochloride 0.05%

🧪 Inactive Ingredients 22 words ▾

Inactive ingredients benzalkonium chloride solution, benzyl alcohol, dibasic sodium phosphate, edetate disodium, monobasic sodium phosphate, polyethylene glycol, povidone, propylene glycol, purified water

🎯 Purpose 3 words ▾

Purpose Nasal decongestant

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 72288-0303-91 · Amazon.com 72288-0310-06 · Amazon.com →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.