Furosemide Injection

241 interactions 649 cited references

Also sold as: Disal Furoscix Furoscix® Lasix Lasix® Salix - substance

About Furosemide Injection

Furosemide injection is used in adults and children who cannot take oral medications or in emergency situations to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart failure, pulmonary edema (excess fluid in the lungs), kidney, and liver disease. Furosem… Read the full Furosemide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Methenamine Desmopressin Vonoprazan Dexibuprofen Dasabuvir Dapagliflozin

2 Contraindicated 195 Major 41 Moderate 3 Minor

All (241) Contraindicated (2) Major (195) Moderate (41) Minor (3)

Moderate

Furosemide Injection Balsalazide Colazal An increased risk of salicylate toxicity Details Furosemide Injection Carbamazepine Carbatrol Hyponatremia Details Furosemide Injection Cephaloridine An increased risk of cephaloridine toxicity Details Furosemide Injection Cholestyramine Prevalite Decreased furosemide effectiveness Details Furosemide Injection Clofibrate Muscle pain and stiffness, accentuation of diuretic effects, and elevations in serum transaminases and creatine phosphokinase Details Furosemide Injection Colestipol Colestid Decreased furosemide effectiveness Details Furosemide Injection Corticotropin Increased electrolyte loss associated with diuretic use, such as potassium Details Furosemide Injection Cortisone Hypokalemia Details Furosemide Injection Cyclosporine Atopica Increased risk of gouty arthritis secondary to furosemide-induced hyperuricemia and cyclosporine impairment of renal urate excreti... Details Furosemide Injection Dibekacin Ototoxicity and/or nephrotoxicity Details Furosemide Injection Digoxin Cardoxin® Increased risk of digoxin toxicity (nausea, vomiting, cardiac arrhythmias) Details Furosemide Injection Dofetilide Tikosyn An increased risk of hypokalemia or hypomagnesemia and an increased risk of torsade de pointes Details Furosemide Injection Dronedarone Multaq Risk of hypokalemia and hypomagnesemia Details Furosemide Injection Droperidol An increased risk of electrolyte imbalance Details Furosemide Injection Fludrocortisone Hypokalemia Details Furosemide Injection Germanium Increased risk of diuretic resistance Details Furosemide Injection Ginseng Increased risk of diuretic resistance Details Furosemide Injection Gossypol Increased risk of hypokalemia Details Furosemide Injection Hydrocortisone Ala-Cort Hypokalemia Details Furosemide Injection Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Furosemide Injection Levalbuterol Xopenex ECG changes or hypokalemia Details Furosemide Injection Licorice Increased risk of hypokalemia and/or reduced effectiveness of the diuretic Details Furosemide Injection Ma Huang Reduced hypotensive effect of loop diuretics Details Furosemide Injection Mesalamine Apriso An increased risk of salicylate toxicity Details Furosemide Injection Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details Furosemide Injection Olodaterol Striverdi An increased risk of ECG changes and/or an increased risk of hypokalemia Details Furosemide Injection Olsalazine Dipentum An increased risk of salicylate toxicity Details Furosemide Injection Oxycodone Oxaydo Reduced efficacy of diuretics Details Furosemide Injection Pancuronium Increased or decreased neuromuscular blockade Details Furosemide Injection Propranolol Hemangeol Hypotension, bradycardia Details Furosemide Injection Sildenafil Liqrev Increased risk of hearing loss Details Furosemide Injection Succinylcholine Anectine Alterations of neuromuscular blockade Details Furosemide Injection Sucralfate Carafate Decreased antihypertensive and natriuretic effects of furosemide Details Furosemide Injection Sulfasalazine Azulfidine An increased risk of salicylate toxicity Details Furosemide Injection Tubocurarine Antagonism of skeletal muscle relaxant effects of tubocurarine Details Furosemide Injection Vecuronium Increased or decreased neuromuscular blockade Details Furosemide Injection Vilanterol An increased risk of ECG changes or hypokalemia Details Furosemide Injection Yohimbine Reduced diuretic effectiveness Details

Minor

Furosemide Injection Hydralazine Apresoline® An enhanced diuretic response to furosemide Details Furosemide Injection Phenprocoumon Altered protein binding of phenprocoumon and furosemide Details

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