Morphine Injection
437 interactions 767 cited referencesMorphine injection is used to relieve moderate to severe pain. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain. Read the full Morphine Injection drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Morphine Injection Chlorpheniramine Increased risk of urinary retention, severe constipation, paralytic ileus and an increased risk of serotonin syndrome Details Morphine Injection Chlorpromazine Increased risk of urinary retention, severe constipation, and paralytic ileus and an increased risk of profound sedation, respirat... Details Morphine Injection Chlorthalidone Hemiclor Reduced efficacy of diuretics Details Morphine Injection Chlorzoxazone Lorzone Increased risk of profound sedation, hypotension, coma and respiratory depression Details Morphine Injection Cimetidine Tagamet Increased risk of apnea, confusion and muscle twitching, an increased morphine exposure and an increased risk of morphine toxicity... Details Morphine Injection Citalopram Celexa Increased risk of serotonin syndrome Details Morphine Injection Clarithromycin Biaxin Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Injection Clemastine Clemasz Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Injection Clidinium Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Injection Clobazam Onfi Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Clomipramine Anafranil An increased risk of serotonin syndrome, an increased risk of CNS depression and an increased risk of urinary retention, severe co... Details Morphine Injection Clonazepam Klonopin Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Clopamide Reduced efficacy of diuretics Details Morphine Injection Clopidogrel Plavix Reduced efficacy of clopidogrel Details Morphine Injection Clorazepate Tranxene Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Cloxazolam Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Clozapine Clozaril Increased risk of urinary retention, severe constipation, and paralytic ileus and an increased risk of profound sedation, respirat... Details Morphine Injection Cobicistat Tybost Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Injection Cocaine Goprelto Increased risk of serotonin syndrome Details Morphine Injection Codeine Tuzistra XR® (as a combination product containing Chlorpheniramine, Codeine) Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Morphine Injection Conivaptan Vaprisol Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Injection Cyclobenzaprine Amrix Increased risk of respiratory and CNS depression, increased risk of serotonin syndrome and an increased risk of urinary retention,... Details Morphine Injection Cyclopenthiazide Reduced efficacy of diuretics Details Morphine Injection Cyclopentolate Cyclogyl Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Injection Cyclosporine Atopica Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Injection Cyclothiazide Reduced efficacy of diuretics Details Morphine Injection Cyproheptadine Increased risk of urinary retention, severe constipation, and paralytic ileus and an increased risk of CNS depression Details Morphine Injection Daclatasvir Daklinza® Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Injection Dantrolene Dantrium Increased degree of respiratory depression Details Morphine Injection Daridorexant An increased risk CNS depression Details Morphine Injection Darifenacin Enablex Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Injection Delorazepam Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Desipramine Norpramin Increased risk of urinary retention, severe constipation, paralytic ileus and an increased risk of serotonin syndrome Details Morphine Injection Desvenlafaxine Pristiq Increased risk of serotonin syndrome Details Morphine Injection Dexmedetomidine Dexased Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Dextroamphetamine Dexedrine Increased risk of serotonin syndrome Details Morphine Injection Dextromethorphan Delsym Increased risk of serotonin syndrome Details Morphine Injection Dezocine Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Morphine Injection Diacetylmorphine Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Injection Diazepam Diastat Increased risk of profound sedation, respiratory depression, hypotension, coma and death DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacist