Vibegron

Name: Vibegron Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

11 interactions 2 explained in plain English

Also sold as: Gemtesa Gemtesa®

About Vibegron

Vibegron is a beta-3 adrenergic agonist used to treat overactive bladder in adults. Read the full Vibegron drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Relugolix Cyclosporine Injection Cyclosporine Ophthalmic Dabigatran Dabigatran Etexilate

1 Contraindicated 10 Major

All (11) Contraindicated (1) Major (10)

Major

Vibegron Relugolix Orgovyx Explained Increased relugolix exposure Details Vibegron Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Vibegron Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Vibegron Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Vibegron Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Vibegron Digoxin Cardoxin® Increased digoxin exposure Details Vibegron Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Vibegron Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Vibegron Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Vibegron Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.