1-androsterone + Human Chorionic Gonadotropin (HCG)
Human Chorionic Gonadotropin (HCG) brand name: Pregnyl.
We found no known interaction between 1-androsterone and Human Chorionic Gonadotropin (HCG) in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
1-androsterone and Human Chorionic Gonadotropin (HCG)
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Human Chorionic Gonadotropin (HCG) and 1-androsterone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
1-androsterone safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Human Chorionic Gonadotropin (HCG)
Interactions in our licensed database are recorded against drug classes, not just single drug names. Human Chorionic Gonadotropin (HCG) is filed under a single classification — thyroid hormone. 1-androsterone has documented interactions with 1 drug class — the most serious being testosterone (moderate) — and none of Human Chorionic Gonadotropin (HCG)’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
1-androsterone Does Interact With Other Medications
1-androsterone has 8 moderate known drug interactions in our database — Human Chorionic Gonadotropin (HCG) isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against 1-androsterone
We haven’t checked that one against 1-androsterone yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against 1-androsterone. Pick one to open its full report.
See Every Supplement That Interacts With Human Chorionic Gonadotropin (HCG)
This page covers 1-androsterone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Human Chorionic Gonadotropin (HCG) page lists 21 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Tiratricol (major), Acetyl-l-carnitine (moderate), Alpha-lipoic Acid (moderate), Ascophyllum Nodosum (moderate) and Ashwagandha (moderate).
By severity: 1 major · 19 moderate · 1 minor.
From our pharmacist’s overview on the Human Chorionic Gonadotropin (HCG) page
“Tiratricol is the entry to understand first. It is a thyroid hormone in its own right, and it carries the only major rating among the 21 supplements known to interact with human chorionic gonadotropin (HCG, sold as Pregnyl).”
Reviewed by 2 · Jul 18, 2026
Open the Human Chorionic Gonadotropin (HCG) interaction page
Taking 1-androsterone as Part of a Dietary Supplement Product? Check It for Interactions
We hold 35 real supplement products containing 1-androsterone, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 1-androsterone. Even though 1-androsterone itself has no known interaction with Human Chorionic Gonadotropin (HCG), another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where 1-androsterone and Human Chorionic Gonadotropin (HCG) Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#605 of 1,452 supplements looked up here in the last 7 days
#79 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 1-androsterone reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The 1-androsterone and Human Chorionic Gonadotropin (HCG) records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About 1-androsterone
What is 1-androsterone?
- Muscle building
- Increasing strength
- Athletic performance
- Body recomposition
1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It can affect hormones and may harm the liver and other organs, so most pharmacists would recommend avoiding it.
Synthetic compound (not a plant part) · Capsules, tablets, sometimes combined with other prohormones
An interaction check asks whether these two react with each other — it does not ask whether 1-androsterone is a good idea for someone in your situation. Here is what our 1-androsterone record says about it on its own.
1-androsterone: dosing
There is no established safe or standard dose for 1-androsterone, and no medical guideline supports its use. Products vary widely in strength and ingredients.Because of the health risks involved, the safest choice for most people is not to use it at all. Never combine it with other prohormones or hormone products.
From our 1-androsterone monograph — the full record covers uses, side effects and every documented interaction.
Other Drugs & 1-androsterone
Browse every other medication we’ve checked against 1-androsterone — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
8 interactions
No interaction 2,821 drugs checked — show the list
We also checked 1-androsterone against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Tadalafil ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Abemaciclib ›
- Hydroxyurea ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Warfarin Sodium ›
- Tirzepatide ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Acyclovir ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Lamotrigine ›
- Fluoxetine ›
- Acetaminophen, Codeine ›
- Amphetamine ›
- Gabapentin ›
- Pregabalin ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Methylene Blue ›
- Quetiapine ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Ciprofloxacin ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,821 medications checked with no known interaction — see the full 1-androsterone list.
1-androsterone References
The 2 references that drive our 1-androsterone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
- Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking 1-androsterone and Human Chorionic Gonadotropin (HCG) Together: Common Questions
Is it safe to take 1-androsterone with Human Chorionic Gonadotropin (HCG)?
How was the 1-androsterone and Human Chorionic Gonadotropin (HCG) combination checked?
Does 1-androsterone interact with any other medications?
Does Human Chorionic Gonadotropin (HCG) interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.