Drug & supplement interaction

4-androsterone + Ceftizoxime

Ceftizoxime brand name: Cefizox.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 4-androsterone and Ceftizoxime in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

4-androsterone and Ceftizoxime

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ceftizoxime and 4-androsterone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

4-androsterone safety at a glance

4-androsterone overall Use caution Prohormones can disrupt hormones, strain the liver, and affect cholesterol; safety is not well studied.
Pregnancy Avoid Androgenic hormones can harm a developing baby; do not use during pregnancy.
Breastfeeding Avoid Hormonal effects on a nursing infant are unknown and potentially harmful; avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ceftizoxime and 4-androsterone? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Ceftizoxime

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ceftizoxime is filed under 5 classifications — including organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates, antibiotic drugs. 4-androsterone has documented interactions with 1 drug class — the most serious being testosterone (moderate) — and none of Ceftizoxime’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

4-androsterone Does Interact With Other Medications

4-androsterone has 8 moderate known drug interactions in our database — Ceftizoxime isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against 4-androsterone

Covers the 2,830 medications we’ve checked against 4-androsterone. Pick one to open its full report.

What to actually watch for

What 4-androsterone Itself Has Been Linked To

This is not an interaction — nothing below involves Ceftizoxime. It is the side-effect record for 4-androsterone on its own, from the licensed Natural Medicines monograph. If something new turns up after you add 4-androsterone, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Kidney problems / Liver problems Worth acting on Additional detail

    “There is insufficient information available about adverse effects associated with 4-androsterone. It is purported that 4-androsterone is metabolized to anabolic compounds. Therefore, in theory, there is concern that it might cause serious anabolic steroid-like side effects including stroke, kidney failure, and liver injury.”

    4-androsterone · Natural Medicines adverse-effect record, reported in kidney failure.

Everything above comes from the Natural Medicines adverse-effect record for 4-androsterone — expand a row for the licensed statement it rests on. We haven’t matched Ceftizoxime to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Ceftizoxime.

Everything else you take

See Every Supplement That Interacts With Ceftizoxime

This page covers 4-androsterone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ceftizoxime page lists 43 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Asarabacca (major), Siberian Cocklebur (major), African Wild Potato (moderate), Aristolochia (moderate) and Bacillus Coagulans (moderate).

By severity: 2 major · 39 moderate · 2 minor.

From our pharmacist’s overview on the Ceftizoxime page

“Ceftizoxime (Cefizox) is an injectable cephalosporin antibiotic given for serious infections, and two of the 43 supplements on this list call for genuine care. Both major-rated entries, Siberian cocklebur and asarabacca, can damage the kidneys on their own, stacking that risk on top of the drug, and asarabacca is often contaminated wit…”

Reviewed by 2 · Jul 18, 2026

Open the Ceftizoxime interaction page

One more smart check

Taking 4-androsterone as Part of a Dietary Supplement Product? Check It for Interactions

We hold 23 real supplement products containing 4-androsterone, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 4-androsterone. Even though 4-androsterone itself has no known interaction with Ceftizoxime, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where 4-androsterone and Ceftizoxime Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 4-androsterone
Top half

#537 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ceftizoxime
Steady interest

#2,442 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. 4-androsterone is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 4-androsterone reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The 4-androsterone and Ceftizoxime records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 4-androsterone

What is 4-androsterone?

  • Muscle building
  • Strength and athletic performance
  • Boosting testosterone
  • Bodybuilding cycles

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human studies are very limited and it carries real risks like liver strain, hormone imbalance, and cholesterol changes. Its legal status is uncertain in many places, and it may cause a positive result on drug tests. We do not recommend it without close medical supervision, and it should be avoided in pregnancy and breastfeeding.

Synthetic steroidal compound (not a plant part) · Capsules, tablets, transdermal gels or creams, liquid drops

An interaction check asks whether these two react with each other — it does not ask whether 4-androsterone is a good idea for someone in your situation. Here is what our 4-androsterone record says about it on its own.

4-androsterone: dosing

There is no established, medically recommended dose for 4-androsterone. Doses used in bodybuilding come from product labels and informal community advice, not from rigorous clinical research.Because purity and strength can vary between products and the risks are significant, we cannot recommend a specific amount. Never assume that a higher dose is safer or more effective.

From our 4-androsterone monograph — the full record covers uses, side effects and every documented interaction.

Read the full 4-androsterone monograph & all interactions
Keep checking

Other Drugs & 4-androsterone

Browse every other medication we’ve checked against 4-androsterone — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
8Moderate
0Minor
2,821No known interaction
Moderate

8 interactions

No interaction 2,821 drugs checked — show the list
Evidence & sources

4-androsterone References

The 3 sources that drive our 4-androsterone monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. 4-androsterone is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Anabolic Steroids and Other Appearance and Performance Enhancing Drugs (APEDs) — NIH National Institute on Drug Abuse Source
  2. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  3. DHEA — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 4-androsterone and Ceftizoxime Together: Common Questions

Is it safe to take 4-androsterone with Ceftizoxime?
We do not list a known interaction between 4-androsterone and Ceftizoxime. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the 4-androsterone and Ceftizoxime combination checked?
Interactions in our licensed database are recorded against drug classes. Ceftizoxime is filed under 5 classifications, and 4-androsterone has documented interactions with 1 drug class — none of Ceftizoxime's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does 4-androsterone interact with any other medications?
Yes. 4-androsterone has 8 documented drug interactions in our database — Ceftizoxime is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Ceftizoxime interact with any supplements?
Yes. Ceftizoxime has documented interactions with 43 supplements in our database — 4-androsterone is not one of them. The Ceftizoxime interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ceftizoxime and 4-androsterone?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.