Drug & supplement interaction

Abuta + Perindopril Erbumine

Perindopril Erbumine brand name: Aceon.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Abuta and Perindopril Erbumine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Abuta and Perindopril Erbumine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Perindopril Erbumine and Abuta in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Abuta safety at a glance

Abuta overall Use caution Human safety data are limited, so use cautiously and under professional guidance.
Pregnancy Avoid Traditionally used to affect the uterus and childbirth; avoid during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding; best avoided.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Perindopril Erbumine and Abuta? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Perindopril Erbumine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Perindopril Erbumine is filed under 4 classifications — including ace inhibitors (aceis), antihypertensive drugs, nephrotoxic drugs. Abuta has documented interactions with 1 drug class — the most serious being diuretic drugs (moderate) — and none of Perindopril Erbumine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Abuta Does Interact With Other Medications

Abuta has 75 moderate known drug interactions in our database — Perindopril Erbumine isn’t one of them. If you take anything else, check it against the full list below.

Moderate 75 No known interaction 2,755 (incl. Perindopril Erbumine)
Taking anything else?

Check Another of Your Medications Against Abuta

Covers the 2,830 medications we’ve checked against Abuta. Pick one to open its full report.

What to actually watch for

What Perindopril Erbumine’s Own FDA Label Lists

This is not an interaction — none of it involves Abuta. These are the most notable effects listed in the ADVERSE REACTIONS section of Perindopril Erbumine’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • High potassium Worth acting on
  • Low sodium Worth acting on
  • Pancreatitis Worth acting on
  • Yellowing of the skin or eyes Worth acting on
  • Raised blood pressure Worth acting on mentioned in 4.7% of FDA reports for Perindopril Erbumine
  • A low platelet count Worth acting on
  • Kidney problems Worth acting on
  • Anemia Worth acting on
  • A severe allergic reaction Worth acting on
  • A low white blood cell count Worth acting on

Showing the 10 most notable of 21 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Perindopril Erbumine. Read the label on DailyMed › Where a percentage is shown, it is the share of 5,566 voluntary FDA FAERS reports for Perindopril Erbumine that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Abuta’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Abuta side to compare — that is a limit of the record, not a statement that Abuta has no side effects.

Overlapping uses

What Perindopril Erbumine Is Prescribed For, and What Abuta Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Perindopril Erbumine is a prescription medicine with approved uses on its FDA label. Abuta is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Perindopril Erbumine is prescribed for: Perindopril erbumine tablets treat essential hypertension (high blood pressure with no single identified cause). They can be used alone or with other blood pressure medicines, especially thiazide diuretics (water pills). They are also used in people with stable coronary artery disease (narrowed heart arteries). Here, the goal is to lower the risk of cardiovascular death or a nonfatal heart attack.

Read the rest of what Perindopril Erbumine is prescribed for

They can be added to usual care such as antiplatelet, blood pressure or cholesterol-lowering medicines.

Abuta has been studied for:

  • Hypertension studied, not established Abuta has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Abuta for hypertension

    Although there has been interest in using oral abuta for hypertension, there is insufficient reliable information about the clinical effects of abuta for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Perindopril Erbumine on your own; if you are taking Abuta for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Abuta or Perindopril Erbumine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Abuta or Perindopril Erbumine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Perindopril Erbumine

This page covers Abuta only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Perindopril Erbumine page lists 149 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Siberian Cocklebur (major).

By severity: 6 major · 119 moderate · 24 minor.

Open the Perindopril Erbumine interaction page

One more smart check

Taking Abuta as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Abuta, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Abuta. Even though Abuta itself has no known interaction with Perindopril Erbumine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Abuta and Perindopril Erbumine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Abuta
Steady interest

#756 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Perindopril Erbumine
Top 25%

#639 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Abuta reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Abuta and Perindopril Erbumine records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Abuta

What is Abuta?

Abuta
  • Menstrual cramps and women's health
  • Kidney and urinary tract complaints
  • Digestive upset
  • Fever
  • Traditional support during pregnancy and childbirth

Abuta (Cissampelos pareira) is a tropical climbing plant used in traditional medicine, especially for menstrual and urinary complaints. Good-quality human studies are lacking, so its benefits and safety are not well established. Because of uncertain safety—and its traditional use to affect the uterus—it should be avoided during pregnancy and breastfeeding and discussed with a pharmacist or doctor first.

Cissampelos pareira · Menispermaceae · Root (most common), with bark, seeds, and above-ground parts also used · Dried root, tea/decoction, tincture, capsules, powder

An interaction check asks whether these two react with each other — it does not ask whether Abuta is a good idea for someone in your situation. Here is what our Abuta record says about it on its own.

Abuta: dosing

There is no established, standardized dose of abuta. Traditional preparations vary, and modern supplements come in different strengths and forms, so there is no single recommended amount that has been proven safe and effective.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Abuta monograph — the full record covers uses, side effects and every documented interaction.

Read the full Abuta monograph & all interactions
Medication

About Perindopril

What Is Perindopril Used For?

Brand name: Aceon

Perindopril erbumine tablets treat essential hypertension (high blood pressure with no single identified cause). They can be used alone or with other blood pressure medicines, especially thiazide diuretics (water pills).

They are also used in people with stable coronary artery disease (narrowed heart arteries). Here, the goal is to lower the risk of cardiovascular death or a nonfatal heart attack. They can be added to usual care such as antiplatelet, blood pressure or cholesterol-lowering medicines.

Most-Reported Side Effects for Perindopril Erbumine

From FAERS, the FDA’s public side-effect reporting system (5,566 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 361 reports
Malaise 320 reports
Fall 288 reports
Fatigue 262 reports
Diarrhea 259 reports
See full Perindopril drug information
Keep checking

Other Drugs & Abuta

Browse every other medication we’ve checked against Abuta — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
75Moderate
0Minor
2,754No known interaction
75 Moderate 2,754 No interaction
Moderate

75 interactions

Showing 60 of 75 moderate interactions — see all 75 on the Abuta page.

No interaction 2,754 drugs checked — show the list

We also checked Abuta against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,754 medications checked with no known interaction — see the full Abuta list.

See the full Abuta interactions page
See every supplement checked against Perindopril Erbumine, ranked by severity
Evidence & sources

Abuta References

The 1 references that drive our Abuta monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sayana SB, Khanwelkar CC, Nimmagadda VR, et al. Evaluation of diuretic activity of alcoholic extract of roots of cissampelos pareira in albino rats. J Clin Diagn Res. 2014;8(5):HC01-4.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Abuta and Perindopril Erbumine Together: Common Questions

Is it safe to take Abuta with Perindopril Erbumine?
We do not list a known interaction between Abuta and Perindopril Erbumine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Abuta and Perindopril Erbumine used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Abuta in each. That is a conversation for your prescriber, especially if Perindopril Erbumine is being adjusted to a target.
How was the Abuta and Perindopril Erbumine combination checked?
Interactions in our licensed database are recorded against drug classes. Perindopril Erbumine is filed under 4 classifications, and Abuta has documented interactions with 1 drug class — none of Perindopril Erbumine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Abuta interact with any other medications?
Yes. Abuta has 75 documented drug interactions in our database — Perindopril Erbumine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Perindopril Erbumine interact with any supplements?
Yes. Perindopril Erbumine has documented interactions with 149 supplements in our database — Abuta is not one of them. The Perindopril Erbumine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Abuta monograph Uses, safety profile, and every drug interaction in one place Perindopril drug information The full plain-English guide to this medication Perindopril Erbumine supplement interactions Every supplement checked against Perindopril Erbumine, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Perindopril Erbumine and Abuta?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.