Drug & supplement interaction

Acai + Etodolac

Etodolac brand names: Lodine, Lodine XL, Ultradol, Etodolac.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated June 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Acai and Etodolac in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Acai and Etodolac

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Etodolac and Acai in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Acai safety at a glance

Acai overall Use caution Acai is generally well tolerated as a food, but supplement quality and high-dose effects are not well studied.

Pregnancy Use caution Acai as a food is likely fine, but concentrated supplements have not been studied in pregnancy, so it is best to use caution.

Breastfeeding Use caution There is not enough safety information on acai supplements during breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Etodolac and Acai? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Etodolac

Interactions in our licensed database are recorded against drug classes, not just single drug names. Etodolac is filed under 6 classifications — including nonsteroidal anti-inflammatory drugs (nsaids), organic anion transporter 3 (oat3) substrates, organic anion transporter 1 (oat1) substrates. Acai has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Etodolac’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Acai Does Interact With Other Medications

Acai has 86 moderate known drug interactions in our database — Etodolac isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Etodolac)

Taking anything else?

Check Another of Your Medications Against Acai

Covers the 2,830 medications we’ve checked against Acai. Pick one to open its full report.

What to actually watch for

What Etodolac’s Own FDA Label Lists

This is not an interaction — none of it involves Acai. These are the most notable effects listed in the ADVERSE REACTIONS section of Etodolac’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

Hearing loss Worth acting on
A stroke or mini-stroke Worth acting on
Pain or burning when passing urine Worth acting on
Bleeding in the gut Worth acting on
A heart attack Worth acting on
Hallucinations Worth acting on
Pancreatitis Worth acting on
Yellowing of the skin or eyes Worth acting on
Heart failure Worth acting on
High blood sugar Worth acting on

Showing the 10 most notable of 66 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Etodolac. Read the label on DailyMed › Where a percentage is shown, it is the share of 5,959 voluntary FDA FAERS reports for Etodolac that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Acai’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Acai side to compare — that is a limit of the record, not a statement that Acai has no side effects.

Overlapping uses

What Etodolac Is Prescribed For, and What Acai Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Etodolac is a prescription medicine with approved uses on its FDA label. Acai is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Etodolac is prescribed for: Etodolac capsules and tablets are used to manage the signs and symptoms of osteoarthritis and rheumatoid arthritis, both short-term and long-term. They are also used for acute pain relief. Etodolac extended-release tablets are indicated for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, and juvenile arthritis (in patients aged 6 to 16).

Acai has been studied for:

Osteoarthritis studied, not established Acai has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

Acai for osteoarthritis

Although there is interest in using oral acai for osteoarthritis, there is insufficient reliable information about the clinical effects of acai for this condition.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Etodolac on your own; if you are taking Acai for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Acai or Etodolac

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Acai or Etodolac, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Etodolac

This page covers Acai only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Etodolac page lists 52 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 35 moderate · 12 minor.

From our pharmacist’s overview on the Etodolac page

“Etodolac (Lodine) is an NSAID for arthritis and other pain, and NSAIDs already stress the stomach lining and the kidneys, so the supplements on this page deserve more than a glance. Five of the 52 entries are rated major, and those five are where I would start reading.”

Reviewed by 2 · Jul 18, 2026

Open the Etodolac interaction page

One more smart check

Taking Acai as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3,313 real supplement products containing Acai, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Acai. Even though Acai itself has no known interaction with Etodolac, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Acai and Etodolac Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Acai

Top 10%

#102 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Etodolac

Steady interest

#2,387 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Acai reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Acai and Etodolac records this page draws on were last updated June 22, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Acai

What is Acai?

Antioxidant support
Weight loss
Energy and vitality
Heart health
General wellness ('superfood')

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacking for the bold health claims often attached to acai supplements, including weight loss and disease prevention.

Euterpe oleracea · Arecaceae · Fruit (berry) and its pulp · Juice, frozen pulp, smoothie packs, powder, capsules, tablets

An interaction check asks whether these two react with each other — it does not ask whether Acai is a good idea for someone in your situation. Here is what our Acai record says about it on its own.

Acai: dosing

There is no officially established or standardized dose for acai. Amounts used in studies and products vary widely depending on the form (juice, pulp, powder, or capsule).The best approach is to follow the directions on the product label and not exceed the recommended amount.

From our Acai monograph — the full record covers uses, side effects and every documented interaction.

Read the full Acai monograph & all interactions

Medication

About Etodolac

What Is Etodolac Used For?

Brand names: Lodine, Lodine XL, Ultradol, Etodolac

Etodolac capsules and tablets are used to manage the signs and symptoms of osteoarthritis and rheumatoid arthritis, both short-term and long-term. They are also used for acute pain relief.

Etodolac extended-release tablets are indicated for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, and juvenile arthritis (in patients aged 6 to 16).

Most-Reported Side Effects for Etodolac

From FAERS, the FDA’s public side-effect reporting system (5,959 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 292 reports

Arthralgia 285 reports

Fatigue 279 reports

Headache 240 reports

Diarrhea 235 reports

See full Etodolac drug information

Keep checking

Other Drugs & Acai

Browse every other medication we’ve checked against Acai — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

86Moderate

0Minor

2,743No known interaction

86 Moderate 2,743 No interaction

Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Acai page.

No interaction 2,743 drugs checked — show the list

We also checked Acai against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Acai list.

See the full Acai interactions page

See every supplement checked against Etodolac, ranked by severity

Evidence & sources

Acai References

The 2 references that drive our Acai monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of acai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J 2011;10:45.
de Liz S, Cardoso AL, Copetti CLK, et al. Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study. Clin Nutr. 2020;39(12):3629-3636. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Acai and Etodolac Together: Common Questions

Is it safe to take Acai with Etodolac?

We do not list a known interaction between Acai and Etodolac. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Are Acai and Etodolac used for the same thing?

They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Acai in each. That is a conversation for your prescriber, especially if Etodolac is being adjusted to a target.

How was the Acai and Etodolac combination checked?

Interactions in our licensed database are recorded against drug classes. Etodolac is filed under 6 classifications, and Acai has documented interactions with 1 drug class — none of Etodolac's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Acai interact with any other medications?

Yes. Acai has 86 documented drug interactions in our database — Etodolac is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Etodolac interact with any supplements?

Yes. Etodolac has documented interactions with 52 supplements in our database — Acai is not one of them. The Etodolac interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Acai monograph Uses, safety profile, and every drug interaction in one place Etodolac drug information The full plain-English guide to this medication Etodolac supplement interactions Every supplement checked against Etodolac, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Etodolac and Acai?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.