Medication interaction hub

What Supplements Interact with Etodolac?

Etodolac brand names: Lodine, Lodine XL, Ultradol, Etodolac. Every interaction below applies to the brands too.

52 Interactions 5 Major 35 Moderate 12 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Etodolac? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Etodolac against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Etodolac (Lodine) is an NSAID for arthritis and other pain, and NSAIDs already stress the stomach lining and the kidneys, so the supplements on this page deserve more than a glance. Five of the 52 entries are rated major, and those five are where I would start reading. Beer and wine are two of them, since alcohol alongside an NSAID raises the chance of gastrointestinal bleeding, and activated charcoal can bind the drug and blunt its effect.

The 35 moderate and 12 minor entries mostly fall into a few patterns. Twenty ingredients add to sun sensitivity, a handful of herbs can pile extra strain on kidneys already working harder because of the NSAID, and a group of bulky or absorbent products can interfere with how oral medicines are absorbed. Space those well apart from each dose, and treat the kidney entries as seriously as the alcohol ones.

— , Clinical Pharmacist · July 18, 2026

Major 5 Moderate 35 Minor 12 No known interaction 1,400

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Etodolac: Top Interactions at a Glance

The Etodolac supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 52 interacting ingredients — plus 1,400 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Etodolac Combinations Today

The Etodolac + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Probable Masterwort + Etodolaci

The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effects.

Read the full interaction Moderate Likelihood Possible Lime + Etodolaci

Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.

Read the full interaction Moderate Likelihood Possible Alfalfa + Etodolaci

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Read the full interaction Major Likelihood Probable Beer + Etodolaci

Concomitant use may increase the risk of gastrointestinal (GI) bleeding.

Read the full interaction Major Likelihood Likely Siberian Cocklebur + Etodolaci

Siberian cocklebur can adversely affect the kidney.

Read the full interaction Major Likelihood Probable Activated Charcoal + Etodolaci

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction
The complete list

Every Supplement Checked Against Etodolac

All 1,452 ingredients in our database, ranked by severity — 52 with a Etodolac interaction on file and 1,400 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Etodolac?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Masterwort with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. The use of masterwort in conjunction with photosensitizing drugs is contraindicated due to the potential for additive photosensitizing effec...

Full Masterwort + Etodolac answer

Can you take Lime with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of lime oil with photosensitizing drugs may increase the risk of phototoxicity.

Full Lime + Etodolac answer

Can you take Alfalfa with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.

Full Alfalfa + Etodolac answer

Can you take Beer with Etodolac?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase the risk of gastrointestinal (GI) bleeding.

Full Beer + Etodolac answer

Can you take Siberian Cocklebur with Etodolac?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Siberian cocklebur can adversely affect the kidney.

Full Siberian Cocklebur + Etodolac answer

Can you take Activated Charcoal with Etodolac?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the rout...

Full Activated Charcoal + Etodolac answer

Can you take Wine with Etodolac?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Concomitant use may increase the risk of gastrointestinal (GI) bleeding.

Full Wine + Etodolac answer

Can you take Asarabacca with Etodolac?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Asarabacca, a herbaceous plant, is often contaminated with aristolochic acid, a compound known for its nephrotoxic effects.

Full Asarabacca + Etodolac answer

Can you take Bergamot with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.

Full Bergamot + Etodolac answer

Can you take Chenopodium Oil with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.

Full Chenopodium Oil + Etodolac answer

Can you take Chlorophyll with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.

Full Chlorophyll + Etodolac answer

Can you take Chlorophyllin with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of chlorophyllin with photosensitizing drugs may have additive effects.

Full Chlorophyllin + Etodolac answer

Can you take Coffee Charcoal with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...

Full Coffee Charcoal + Etodolac answer

Can you take European Mandrake with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Etodolac answer

Can you take Glucomannan with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.

Full Glucomannan + Etodolac answer

Can you take Lithium with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking lithium supplements with NSAIDs might increase lithium levels and adverse effects.

Full Lithium + Etodolac answer

Can you take Wild Carrot with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might result in increased photosensitivity.

Full Wild Carrot + Etodolac answer

Can you take African Wild Potato with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro evidence shows that African wild potato extract inhibits OAT3.

Full African Wild Potato + Etodolac answer

Can you take Angelica Archangelica with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Angelica archangelica, whether ingested or applied to the skin, has the potential to induce photosensitivity reactions.

Full Angelica Archangelica + Etodolac answer

Can you take Aristolochia with Etodolac?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Aristolochia is nephrotoxic.

Full Aristolochia + Etodolac answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Etodolac is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Etodolac, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Etodolac sits in 6 interaction categories. Open any one to see what the group means:

Photosensitizing Drugs 20 ingredients

Medications that make skin more sun-sensitive. Supplements with the same property can compound it.

20 of the supplement ingredients on this page reach Etodolac through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Etodolac through this category.

Nephrotoxic Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Etodolac through this category.

Nonsteroidal Anti-Inflammatory Drugs (Nsaids) 5 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

5 of the supplement ingredients on this page reach Etodolac through this category.

Organic Anion Transporter 1 (Oat1) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Etodolac through this category.

Organic Anion Transporter 3 (Oat3) Substrates 4 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

4 of the supplement ingredients on this page reach Etodolac through this category.

About Etodolac

Etodolac is an NSAID used to relieve pain, swelling, and stiffness from osteoarthritis, rheumatoid arthritis, and other causes.

Generic name: Etodolac  ·  Brand names: Lodine, Lodine XL, Ultradol, Etodolac.

See the full Etodolac drug information
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Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Etodolac.

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Pharmacist Counseling Corner

Etodolac & Supplements: Common Questions

What supplements interact with Etodolac?
In our interaction database, 52 supplement and herbal ingredients have an interaction with Etodolac on file — 5 rated major, 35 moderate, and 12 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Siberian Cocklebur, Activated Charcoal, Beer.
Which Etodolac supplement interactions are the most serious?
Focus on the major group: Siberian Cocklebur, Activated Charcoal, Beer, Wine and Asarabacca. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Etodolac?
That depends entirely on which supplement. The honest answer for Etodolac is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Lodine have the same supplement interactions as Etodolac?
Yes — Lodine, Lodine XL, Ultradol, Etodolac all contain Etodolac, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Etodolac and my other medications?
This page covers Etodolac against supplements and herbal ingredients. Checking Etodolac against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Etodolac drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.