Drug & supplement interaction

Androsterone + Diethylpropion

Diethylpropion brand names: Radtue, Tenuate, Durad, Tenuate Dosepan.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Androsterone and Diethylpropion in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Androsterone and Diethylpropion

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diethylpropion and Androsterone in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Androsterone safety at a glance

Androsterone overall Avoid It is a controlled anabolic-androgenic steroid that is illegal to sell as a dietary supplement in the U.S.
Pregnancy Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diethylpropion and Androsterone? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Diethylpropion

Interactions in our licensed database are recorded against drug classes, not just single drug names. Diethylpropion is filed under 2 classifications — stimulant drugs, oral drugs. Androsterone has documented interactions with 1 drug class — the most serious being androgens (minor) — and none of Diethylpropion’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Androsterone Does Interact With Other Medications

Androsterone has 9 minor known drug interactions in our database — Diethylpropion isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Androsterone

Covers the 2,830 medications we’ve checked against Androsterone. Pick one to open its full report.

What to actually watch for

What Androsterone Itself Has Been Linked To

This is not an interaction — nothing below involves Diethylpropion. It is the side-effect record for Androsterone on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Androsterone, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on Additional detail

    “Orally, androsterone is possibly unsafe. As an anabolic androgenic steroid, there is concern that it might cause serious side effects including heart disease and liver injury.”

    Androsterone · Natural Medicines adverse-effect record, reported in cardiovascular disease (cvd).

Everything above comes from the Natural Medicines adverse-effect record for Androsterone — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Diethylpropion’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Diethylpropion column appears here.

Special populations

Androsterone in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Diethylpropion Is Prescribed For, and What Androsterone Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Diethylpropion is a prescription medicine with approved uses on its FDA label. Androsterone is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Diethylpropion is prescribed for: Diethylpropion is used to help manage exogenous obesity (excess body weight from outside factors like diet) in adults with a body mass index (BMI) of 30 or higher who haven't lost enough weight through diet and exercise alone. It is meant to be used for only a few weeks as part of a calorie-restricted diet plan. All available tablet products — both the immediate-release tablets and the extended-release tablets — are approved for this purpose. Each is approved for use as a single medication only; combining diethylpropion with any other weight-loss drug is not allowed.

Androsterone has been studied for:

  • Obesity studied, not established Androsterone has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Androsterone for obesity

    Although there is interest in using oral androsterone for weight loss and reducing abdominal obesity, there is insufficient reliable information about the clinical effects of androsterone for these uses.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Diethylpropion on your own; if you are taking Androsterone for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Diethylpropion

This page covers Androsterone only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diethylpropion page lists 61 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Ephedra (major), Peyote (major), Rauvolfia Vomitoria (major) and Sida Cordifolia (major).

By severity: 5 major · 43 moderate · 13 minor.

From our pharmacist’s overview on the Diethylpropion page

“Diethylpropion (Tenuate) is an appetite suppressant that works by revving up the nervous system, and that mechanism is why its interaction list calls for real vigilance. Of the 61 supplements and herbs on file, 44 add their own stimulant push, raising the risk of high blood pressure, a pounding heart, and sleeplessness.”

Reviewed by 2 · Jul 18, 2026

Open the Diethylpropion interaction page

One more smart check

Taking Androsterone as Part of a Dietary Supplement Product? Check It for Interactions

We hold 12 real supplement products containing Androsterone, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Androsterone. Even though Androsterone itself has no known interaction with Diethylpropion, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Androsterone and Diethylpropion Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Androsterone
Steady interest

#1,034 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Diethylpropion
Steady interest

#1,681 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Androsterone reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Androsterone and Diethylpropion records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Androsterone

What is Androsterone?

Androsterone
  • Muscle building and athletic performance
  • Boosting testosterone or androgen levels
  • Supporting libido
  • Bodybuilding 'prohormone' stacks

Androsterone is a natural androgenic steroid hormone made in the body, but supplement versions are classified as anabolic-androgenic steroids and are banned from U.S. dietary supplements under the DASCA law. There is no good evidence that taking it is safe or effective, and it carries the same hormone-related risks as other anabolic steroids. Avoid products that contain it, and talk to a pharmacist or doctor about safer, legal options.

Not applicable (a steroid hormone, not a plant) · Historically sold as oral capsules, tablets, and sublingual products in 'prohormone' supplements (now banned in the U.S.)

An interaction check asks whether these two react with each other — it does not ask whether Androsterone is a good idea for someone in your situation. Here is what our Androsterone record says about it on its own.

Androsterone: dosing

There is no established or recommended safe dose of androsterone as a supplement, and it is illegal to sell in U.S. dietary supplements. We do not provide dosing for it.If you see a product that lists androsterone or one of its alternate names on the label, treat it as a banned anabolic steroid rather than a normal supplement.

From our Androsterone monograph — the full record covers uses, side effects and every documented interaction.

Read the full Androsterone monograph & all interactions
Medication

About Diethylpropion

What Is Diethylpropion Used For?

Brand names: Radtue, Tenuate, Durad, Tenuate Dosepan

Diethylpropion is used to help manage exogenous obesity (excess body weight from outside factors like diet) in adults with a body mass index (BMI) of 30 or higher who haven't lost enough weight through diet and exercise alone. It is meant to be used for only a few weeks as part of a calorie-restricted diet plan.

All available tablet products — both the immediate-release tablets and the extended-release tablets — are approved for this purpose. Each is approved for use as a single medication only; combining diethylpropion with any other weight-loss drug is not allowed.

See full Diethylpropion drug information
Keep checking

Other Drugs & Androsterone

Browse every other medication we’ve checked against Androsterone — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
9Minor
2,820No known interaction
Minor

9 interactions

No interaction 2,820 drugs checked — show the list
Evidence & sources

Androsterone References

The 1 references that drive our Androsterone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Androsterone and Diethylpropion Together: Common Questions

Is it safe to take Androsterone with Diethylpropion?
We do not list a known interaction between Androsterone and Diethylpropion. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Androsterone and Diethylpropion used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Androsterone in each. That is a conversation for your prescriber, especially if Diethylpropion is being adjusted to a target.
How was the Androsterone and Diethylpropion combination checked?
Interactions in our licensed database are recorded against drug classes. Diethylpropion is filed under 2 classifications, and Androsterone has documented interactions with 1 drug class — none of Diethylpropion's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Androsterone interact with any other medications?
Yes. Androsterone has 9 documented drug interactions in our database — Diethylpropion is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Diethylpropion interact with any supplements?
Yes. Diethylpropion has documented interactions with 61 supplements in our database — Androsterone is not one of them. The Diethylpropion interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Diethylpropion and Androsterone?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.