Drug & supplement interaction

Beer + Lasmiditan Succinate

Lasmiditan Succinate brand name: Reyvow.

Major Interaction
The bottom line Major

Beer has a major interaction with Lasmiditan Succinate. Concomitant use may increase sedative and other adverse effects.

Read the full interaction report
SeverityMajor
LikelihoodLikely
EvidenceC
What do Severity, Likelihood & Evidence mean?
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Interaction report

Beer and Lasmiditan Succinate

Here is the interaction we found between these two, with the evidence behind it.

Major

CNS DEPRESSANTS

Why this applies to Lasmiditan Succinate

Lasmiditan Succinate falls under CNS DEPRESSANTS — the group Beer interacts with.

Concomitant use may increase sedative and other adverse effects.
Concomitant use of alcohol with CNS depressants can increase sedative and other adverse effects, potentially through inhibition of the metabolism of certain CNS depressants.
Severity Major Likelihood Likely Evidence C

Well-controlled human studies have demonstrated the likely existence of this interaction.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the thing about mixing beer with Reyvow (lasmiditan): both can slow down your central nervous system. Lasmiditan already tends to make people drowsy, dizzy, and a bit foggy or unsteady. Add alcohol on top, and those effects can stack and become stronger. You could feel extra sleepy, lightheaded, or off-balance, which raises your risk of falls or trouble concentrating. This isn't about beer activating the drug; lasmiditan works on its own, so the real issue is simply two sedating things piling up.

This is considered a real and likely concern, so my honest advice is to be cautious. Please check with your pharmacist or doctor before drinking beer while taking lasmiditan, especially since you shouldn't drive for at least 8 hours after a dose anyway.

References
  1. Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997;33:79-90. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Beer Also Interacts With Other Medications

Beer has 653 major, 272 moderate known drug interactions in our database — the Lasmiditan Succinate one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Beer

Covers the 2,830 medications we’ve checked against Beer. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Lasmiditan Succinate

This page covers Beer only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lasmiditan Succinate page lists 110 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Gamma-hydroxybutyrate (ghb) (major), Kava (major) and L-tryptophan (major).

By severity: 8 major · 87 moderate · 15 minor.

From our pharmacist’s overview on the Lasmiditan Succinate page

“Sedation is the thread running through most of this page. Lasmiditan (Reyvow) treats migraine attacks and is drowsy-making enough that patients are told not to drive for eight hours after a dose, so the many supplements here with sedative pull of their own deserve genuine wariness; kava and even a beer or glass of wine carry major rati…”

Reviewed by 2 · Jul 18, 2026

Open the Lasmiditan Succinate interaction page

How much people look this up

Where Beer and Lasmiditan Succinate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Beer
Top 25%

#330 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lasmiditan Succinate
Top half

#1,365 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Beer

What is Beer?

Beer
  • Social and recreational drinking
  • Relaxation
  • Heart health (popular belief)
  • Bone health (popular belief)
  • Source of antioxidants and B vitamins

Beer is an alcoholic beverage that contains some minerals, B vitamins, and plant compounds from hops and grain, but it is not a health supplement. Any possible benefits come only from light-to-moderate intake, and they are easily outweighed by the well-known harms of alcohol. The safest amount of alcohol for health is none, and beer should be avoided in pregnancy and breastfeeding.

Read the full Beer monograph & all interactions
Medication

About Lasmiditan

What Is Lasmiditan Used For?

Brand name: Reyvow

Reyvow (lasmiditan) is used to treat migraine attacks in adults, whether or not the migraine comes with an aura (visual or sensory symptoms that can appear before or during the headache). It is taken when a migraine starts — not used daily to prevent migraines from happening.

Reyvow is not intended for preventive (daily) migraine therapy. It is meant to stop an attack that has already begun.

See full Lasmiditan drug information
Keep checking

Other Drugs & Beer

Browse every other medication we’ve checked against Beer — both the ones with a known interaction and the ones without. Select any drug for the full detail.

653Major
272Moderate
0Minor
1,904No known interaction
Major

653 interactions

Showing 60 of 653 major interactions — see all 653 on the Beer page.

Moderate

272 interactions

Showing 60 of 272 moderate interactions — see all 272 on the Beer page.

No interaction 1,904 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Beer and Lasmiditan Succinate Together: Common Questions

Can you take Beer with Lasmiditan Succinate?
This is rated a major interaction, so the combination is best avoided unless your doctor or pharmacist has specifically told you otherwise. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Beer and Lasmiditan Succinate interaction?
We rate it Major. This is a clinically significant combination that is generally best avoided, or used only under the direct supervision of your physician or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Lasmiditan Succinate and Beer?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.