Drug & supplement interaction

Biofeedback + Pregabalin

Pregabalin brand names: Lyrica, Lyrica CR.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Biofeedback and Pregabalin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Biofeedback and Pregabalin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pregabalin and Biofeedback in our sources. This does not guarantee that the combination is completely free of risk — research on Biofeedback alongside specific medications may be limited.

Biofeedback is a treatment rather than something you take. Tell whoever provides it which medicines you use, and ask your prescriber whether it is appropriate for your health and treatment. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Biofeedback safety at a glance

Biofeedback overall Generally safe Biofeedback is non-invasive and considered very safe for most people.
Pregnancy Generally safe Generally considered safe in pregnancy and sometimes used for stress, but check with your provider first.
Breastfeeding Generally safe There is no known risk while breastfeeding since nothing is ingested.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pregabalin and Biofeedback? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Pregabalin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Pregabalin is filed under 3 classifications — including cns depressants, oral drugs. Biofeedback has documented interactions with 1 drug class — the most serious being seizure threshold lowering drugs (moderate) — and none of Pregabalin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Biofeedback Does Interact With Other Medications

Biofeedback has 418 moderate known drug interactions in our database — Pregabalin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 418 No known interaction 2,412 (incl. Pregabalin)
Taking anything else?

Check Another of Your Medications Against Biofeedback

Covers the 2,830 medications we’ve checked against Biofeedback. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Biofeedback and Pregabalin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so having Biofeedback while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on Additional detail

    Biofeedback

    “Biofeedback is generally well tolerated. Electroencephalogram (EEG) biofeedback has been linked to reports of headaches, tiredness, dizziness, and decreased or increased seizure threshold. The tape from biofeedback sensors can cause skin irritation in some people.”

    Biofeedback · Natural Medicines adverse-effect record, reported in epilepsy.

    2 sources cited
    1. 16175. Friel PN. EEG biofeedback in the treatment of attention deficit hyperactivity disorder. Altern Med Rev 2007;12:146-51.
    2. 96834. Kent P, Laird R, Haines T. The effect of changing movement and posture using motion-sensor biofeedback, versus guidelines-based care, on the clinical outcomes of people with sub-acute or chronic low back pain-a multicentre, cluster-randomised, placebo-con

    “Electroencephalogram (EEG) biofeedback has been linked to reports of headaches, tiredness, and dizziness. Also, EEG biofeedback can either decrease or increase the seizure threshold depending on where sensors are placed.”

    Biofeedback · Natural Medicines adverse-effect record, reported in epilepsy.

    1 source cited
    1. 16175. Friel PN. EEG biofeedback in the treatment of attention deficit hyperactivity disorder. Altern Med Rev 2007;12:146-51.

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

  • Tiredness / Dizziness / Headache Additional detail

    Biofeedback

    Recorded for Biofeedback in the same Natural Medicines adverse-effect record shown under Seizures above.

    Pregabalin

    Listed in the ADVERSE REACTIONS section of the FDA label for Pregabalin. Read the label on DailyMed ›

Effects for Pregabalin come from the ADVERSE REACTIONS section of its FDA label; effects for Biofeedback come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Pregabalin Is Prescribed For, and What Biofeedback Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Pregabalin is a prescription medicine with approved uses on its FDA label. Biofeedback is a treatment: what follows is what researchers have looked at it for, and how strong that evidence is.

Pregabalin is prescribed for: Pregabalin is used to manage several types of nerve pain, including neuropathic pain from diabetic peripheral neuropathy (nerve damage caused by diabetes) and postherpetic neuralgia (lingering nerve pain after shingles). It is also used to treat fibromyalgia and neuropathic pain associated with spinal cord injury. Lyrica (capsule and oral solution), pregabalin capsules, and pregabalin oral solution are also approved as add-on therapy for partial-onset seizures — Lyrica for patients 1 month and older, and pregabalin capsules for patients 17 years and older. Lyrica CR and pregabalin extended-release tablets are approved only for diabetic peripheral neuropathy pain and postherpetic neuralgia — their effectiveness for fibromyalgia or as seizure add-on therapy has not been established.

Biofeedback has been studied for:

  • Fibromyalgia studied, not established Biofeedback has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Biofeedback for fibromyalgia

    Preliminary clinical research shows that electromyography (EMG) biofeedback reduces measures of pain and tender points in patients with fibromyalgia when compared with sham biofeedback.

    1 source cited
    1. 16173. Babu AS, Mathew E, Danda D, Prakash H. Management of patients with fibromyalgia using biofeedback: a randomized control trial. Indian J Med Sci 2007;61:455-61. DOI

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Pregabalin on your own; if you are taking Biofeedback for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Biofeedback or Pregabalin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Biofeedback or Pregabalin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Pregabalin

This page covers Biofeedback only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pregabalin page lists 95 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 7 major · 73 moderate · 15 minor.

From our pharmacist’s overview on the Pregabalin page

“Pregabalin (Lyrica) calms overactive nerves, which is how it eases nerve pain, seizures, and anxiety, and that calming action stacks with almost everything on this list. Of the 95 supplements and herbs, the large majority add their own sedation on top of pregabalin's, and a few can tip that into genuine danger, with deep sedation and s…”

Reviewed by 2 · Jul 18, 2026

Open the Pregabalin interaction page

How much people look this up

Where Biofeedback and Pregabalin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Biofeedback
Top 25%

#221 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pregabalin
Top 5%

#39 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Biofeedback reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Biofeedback and Pregabalin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Treatment approach

About Biofeedback

What is Biofeedback?

  • Chronic pain
  • Headaches and migraines
  • Anxiety and stress
  • High blood pressure
  • Urinary incontinence
  • Tension and muscle relaxation

Biofeedback is a mind-body technique, not an herb or supplement. It uses sensors to show you real-time information about body functions like heart rate, muscle tension, or skin temperature so you can learn to control them. It is generally very safe and has reasonable evidence for headaches, certain pain conditions, and pelvic floor problems, but it works best alongside standard medical care.

Not applicable (mind-body therapy, not a plant or supplement) · In-office sessions with sensors and a monitor, wearable devices, and home apps

An interaction check asks whether these two react with each other — it does not ask whether Biofeedback is a good idea for someone in your situation. Here is what our Biofeedback record says about it on its own.

Biofeedback: dosing

There is no pill or standard dose for biofeedback because it is a learned skill, not a substance. Treatment is usually given as a series of sessions, often weekly, with practice in between.The number of sessions needed varies by person and condition. Many programs involve several visits before skills are well learned. Home devices and apps come with their own instructions.For best results, work with a qualified, trained biofeedback practitioner and follow their plan.

From our Biofeedback monograph — the full record covers uses, side effects and every documented interaction.

Read the full Biofeedback monograph & all interactions
Medication

About Pregabalin

What Is Pregabalin Used For?

Brand names: Lyrica, Lyrica CR

Pregabalin is used to manage several types of nerve pain, including neuropathic pain from diabetic peripheral neuropathy (nerve damage caused by diabetes) and postherpetic neuralgia (lingering nerve pain after shingles). It is also used to treat fibromyalgia and neuropathic pain associated with spinal cord injury.

Lyrica (capsule and oral solution), pregabalin capsules, and pregabalin oral solution are also approved as add-on therapy for partial-onset seizures — Lyrica for patients 1 month and older, and pregabalin capsules for patients 17 years and older. Lyrica CR and pregabalin extended-release tablets are approved only for diabetic peripheral neuropathy pain and postherpetic neuralgia — their effectiveness for fibromyalgia or as seizure add-on therapy has not been established.

Most-Reported Side Effects for Pregabalin

From FAERS, the FDA’s public side-effect reporting system (270,557 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 15,629 reports
Dizziness 14,844 reports
Nausea 14,507 reports
Headache 13,067 reports
Malaise 12,884 reports
See full Pregabalin drug information
Keep checking

Other Drugs & Biofeedback

Browse every other medication we’ve checked against Biofeedback — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
418Moderate
0Minor
2,411No known interaction
418 Moderate 2,411 No interaction
Moderate

418 interactions

Showing 60 of 418 moderate interactions — see all 418 on the Biofeedback page.

No interaction 2,411 drugs checked — show the list

We also checked Biofeedback against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,411 medications checked with no known interaction — see the full Biofeedback list.

See the full Biofeedback interactions page
See every supplement checked against Pregabalin, ranked by severity
Evidence & sources

Biofeedback References

The 50 references that drive our Biofeedback monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Rett MT, Simoes JA, Herrmann V, et al. Management of stress urinary incontinence with surface electromyography-assisted biofeedback in women of reproductive age. Phys Ther 2007;87;136-42. PubMed
  2. Kibar Y, Demir E, Irkilata C, et al. Effect of biofeedback treatment on spinning top urethra in children with voiding dysfunction. Urology 2007;70:781-5. PubMed
  3. Naimy N, Lindam AT, Bakka A, et al. Biofeedback vs. electrostimulation in the treatment of postdelivery anal incontinence: a randomized, clinical trial. Dis Colon Rectum 2007;50:2040-6. PubMed
  4. Ciancarelli I, Tozzi-Ciancarelli MG, Spacca G, et al. Relationship between biofeedback and oxidative stress in patients wtih chronic migraine. Cephalalgia 2007;27:1136-41.
  5. Babu AS, Mathew E, Danda D, Prakash H. Management of patients with fibromyalgia using biofeedback: a randomized control trial. Indian J Med Sci 2007;61:455-61. DOI
  6. Tsai PS, Chang NC, Chang WY, et al. Blood pressure biofeedback exerts intermediate-term effects on blood pressure and pressure reactivity in individuals with mild hypertension: a randomized controlled study. J Altern Complement Med 2007;13:547-54. PubMed
  7. Friel PN. EEG biofeedback in the treatment of attention deficit hyperactivity disorder. Altern Med Rev 2007;12:146-51.
  8. Byrne CM, Solomon MJ, Young JM, et al. Biofeedback for fecal incontinence: short-term outcomes of 513 consecutive patients and predictors of successful treatment. Dis Colon Rectum 2007;50:417-27. PubMed
  9. Woodford H, Price C. EMG biofeedback for the recovery of motor function after stroke. Cochrane Database Syst Rev 2007;(2):CD004585. DOI
  10. Karavidas MK, Lehrer PM, Vaschillo E, et al. Preliminary results of an open label study of heart rate variability biofeedback for the treatment of major depression. Appl Psychophysiol Biofeedback 2007;32:19-30. PubMed
  11. Heymen S, Scarlett Y, Jones K, et al. Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation. Dis Colon Rectum 2007;50:428-41. PubMed
  12. Qaseem A, Wilt TJ, McLean RM, et al. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians. Ann Intern Med. 2017;166(7):514-530. PubMed
  13. Carpinella I, Cattaneo D, Bonora G, et al. Wearable sensor-based biofeedback training for balance and gait in Parkinson disease: A pilot randomized controlled trial. Arch Phys Med Rehabil. 2017;98(4):622-630.e3. PubMed
  14. Stubberud A, Varkey E, McCrory DC, Pedersen SA, Linde M. Biofeedback as prophylaxis for pediatric migraine: A meta-analysis. Pediatrics. 2016;138(2). pii: e20160675. PubMed
  15. Sielski R, Rief W, Glombiewski JA. Efficacy of biofeedback in chronic back pain: a meta-analysis. Int J Behav Med. 2017;24(1):25-41. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Having Biofeedback While Taking Pregabalin: Common Questions

Is it safe to have Biofeedback while taking Pregabalin?
We do not list a known interaction between Biofeedback and Pregabalin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Biofeedback and Pregabalin have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Biofeedback and Pregabalin used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Biofeedback in each. That is a conversation for your prescriber, especially if Pregabalin is being adjusted to a target.
How was the Biofeedback and Pregabalin combination checked?
Interactions in our licensed database are recorded against drug classes. Pregabalin is filed under 3 classifications, and Biofeedback has documented interactions with 1 drug class — none of Pregabalin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Biofeedback interact with any other medications?
Yes. Biofeedback has 418 documented drug interactions in our database — Pregabalin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Pregabalin interact with any supplements?
Yes. Pregabalin has documented interactions with 95 supplements in our database — Biofeedback is not one of them. The Pregabalin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Biofeedback monograph Uses, safety profile, and every drug interaction in one place Pregabalin drug information The full plain-English guide to this medication Pregabalin supplement interactions Every supplement checked against Pregabalin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 50 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Pregabalin and Biofeedback?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.