Butea Superba + Naltrexone
Naltrexone brand names: Trexan, Depade, Vivitrol.
We found no known interaction between Butea Superba and Naltrexone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Butea Superba and Naltrexone
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Naltrexone and Butea Superba in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Butea Superba safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Naltrexone
Interactions in our licensed database are recorded against drug classes, not just single drug names. Naltrexone is filed under 3 classifications — including hepatotoxic drugs, oral drugs. Butea Superba has documented interactions with 1 drug class — the most serious being phosphodiesterase-5 inhibitors (moderate) — and none of Naltrexone’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Butea Superba Does Interact With Other Medications
Butea Superba has 7 moderate known drug interactions in our database — Naltrexone isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Butea Superba
We haven’t checked that one against Butea Superba yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Butea Superba. Pick one to open its full report.
See Every Supplement That Interacts With Naltrexone
This page covers Butea Superba only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naltrexone page lists 56 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Ashwagandha (moderate).
By severity: 4 major · 43 moderate · 9 minor.
From our pharmacist’s overview on the Naltrexone page
“The single biggest risk on this page is to your liver. Naltrexone (Vivitrol, Depade), prescribed for alcohol and opioid dependence, carries its own warnings about liver stress at higher doses, and 38 of the 56 supplements here share that liability, led by Siberian cocklebur, a major-rated entry tied to outright liver failure.”
Reviewed by 2 · Jul 18, 2026
Taking Butea Superba as Part of a Dietary Supplement Product? Check It for Interactions
We hold 23 real supplement products containing Butea Superba, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Butea Superba. Even though Butea Superba itself has no known interaction with Naltrexone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Butea Superba and Naltrexone Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,172 of 1,452 supplements looked up here in the last 7 days
#347 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Butea Superba reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Butea Superba and Naltrexone records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Butea Superba
What is Butea Superba?
- Erectile dysfunction
- Low libido
- Male sexual performance
- General vitality and energy
- Traditional tonic
Butea superba is a Thai herb traditionally used to support male sexual health, but the human evidence is very limited and mostly small or low-quality. Its safety has not been well studied, so caution is advised, and you should talk with a pharmacist or doctor before trying it—especially if you have a medical condition or take other medicines.
Butea superba · Fabaceae · Root (tuber) · Capsules, tablets, powder, tinctures, topical gels
An interaction check asks whether these two react with each other — it does not ask whether Butea Superba is a good idea for someone in your situation. Here is what our Butea Superba record says about it on its own.
Butea Superba: dosing
There is no well-established or standardized dose for Butea superba. Studies have used different amounts and preparations, so it is hard to recommend a specific, reliable dose.If you choose to use it, follow the directions on the product label and do not exceed them.
From our Butea Superba monograph — the full record covers uses, side effects and every documented interaction.
About Naltrexone
What Is Naltrexone Used For?
Brand names: Trexan, Depade, Vivitrol
Naltrexone Hydrochloride tablets are used to treat alcohol dependence and to block the effects of opioids in people with opioid dependence. The extended-release injectable suspension — sold as Vivitrol and also available as a generic injectable — is used to treat alcohol dependence and to prevent relapse to opioid dependence after a person has completed opioid detoxification.
All formulations are meant to be part of a broader treatment plan that includes counseling and other support — naltrexone works best when it is not used alone.
Most-Reported Side Effects for Naltrexone
From FAERS, the FDA’s public side-effect reporting system (40,504 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Butea Superba
Browse every other medication we’ve checked against Butea Superba — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
7 interactions
No interaction 2,822 drugs checked — show the list
We also checked Butea Superba against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Acetaminophen ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Abemaciclib ›
- Ibuprofen ›
- Methamphetamine ›
- Semaglutide ›
- Sumatriptan ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Bupropion ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Acyclovir ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Methotrexate ›
- Lamotrigine ›
- Fluoxetine ›
- Amphetamine ›
- Pregabalin ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Omeprazole ›
- Quetiapine ›
- Methylene Blue ›
- Amlodipine Besylate ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Ciprofloxacin ›
- Bisoprolol ›
Showing the 60 most looked-up of 2,822 medications checked with no known interaction — see the full Butea Superba list.
Butea Superba References
The 2 references that drive our Butea Superba monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Cherdshewasart W, Nimsakul N. Clinical trial of Butea superba, an alternative herbal treatment for erectile dysfunction. Asian J Androl 2003;5:243-6.
- Cortés-González JR, Arratia-Maqueo JA, Gómez-Guerra LS, Holmberg AR. The use of Butea superba (Roxb.) compared to sildenafil for treating erectile dysfunction. BJU Int 2010;105(2):225-8. doi: 10.1111/j.1464-410X.2009.08748.x.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Butea Superba and Naltrexone Together: Common Questions
Is it safe to take Butea Superba with Naltrexone?
How was the Butea Superba and Naltrexone combination checked?
Does Butea Superba interact with any other medications?
Does Naltrexone interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Naltrexone and Butea Superba?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.