Drug & supplement interaction

Carqueja + Mestranol, Norethynodrel

Mestranol, Norethynodrel brand name: Enovid-E.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Carqueja and Mestranol, Norethynodrel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Carqueja and Mestranol, Norethynodrel

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mestranol, Norethynodrel and Carqueja in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Carqueja safety at a glance

Carqueja overall Use caution Limited human safety data; use cautiously and discuss with a healthcare professional.
Pregnancy Avoid Traditionally avoided and possibly linked to effects on the uterus; do not use.
Breastfeeding Avoid No reliable safety information during breastfeeding, so avoid it.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mestranol, Norethynodrel and Carqueja? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mestranol, Norethynodrel

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mestranol, Norethynodrel is filed under 5 classifications — including contraceptive drugs, cytochrome p450 1a2 (cyp1a2) inhibitors, hepatotoxic drugs. Carqueja has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Mestranol, Norethynodrel’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Carqueja Does Interact With Other Medications

Carqueja has 86 moderate known drug interactions in our database — Mestranol, Norethynodrel isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Mestranol, Norethynodrel)
Taking anything else?

Check Another of Your Medications Against Carqueja

Covers the 2,830 medications we’ve checked against Carqueja. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Mestranol, Norethynodrel

This page covers Carqueja only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mestranol, Norethynodrel page lists 188 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 6 major · 140 moderate · 42 minor.

From our pharmacist’s overview on the Mestranol, Norethynodrel page

“The list for Mestranol and Norethynodrel (Enovid-E, a combined birth control pill) deserves genuine care, because several entries can quietly undo the pill itself. St.”

Reviewed by 2 · Jul 18, 2026

Open the Mestranol, Norethynodrel interaction page

One more smart check

Taking Carqueja as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Carqueja, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Carqueja. Even though Carqueja itself has no known interaction with Mestranol, Norethynodrel, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Carqueja and Mestranol, Norethynodrel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Carqueja
Steady interest

#1,299 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mestranol, Norethynodrel
Steady interest

#2,440 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Carqueja reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Carqueja and Mestranol, Norethynodrel records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Carqueja

What is Carqueja?

  • Digestive upset and bloating
  • Liver and gallbladder support
  • Blood sugar control
  • Weight loss
  • Anti-inflammatory

Carqueja is a South American herb traditionally used as a bitter tea for digestion, liver complaints, and blood sugar. Human evidence is very limited, so its benefits are not well proven. Because safety data are thin, it should be avoided in pregnancy and breastfeeding and used cautiously by everyone else.

Baccharis trimera · Asteraceae · Aerial parts (stems and winged branches) · Tea (infusion or decoction), tincture, capsules, liquid extract

An interaction check asks whether these two react with each other — it does not ask whether Carqueja is a good idea for someone in your situation. Here is what our Carqueja record says about it on its own.

Carqueja: dosing

There is no well-established standardized dose for carqueja. Traditional use is most often as a tea made from the dried aerial parts, but the strength of teas, tinctures, and capsules varies widely between products.The safest approach is to follow the directions on the product label and not exceed the suggested amount.

From our Carqueja monograph — the full record covers uses, side effects and every documented interaction.

Read the full Carqueja monograph & all interactions
Keep checking

Other Drugs & Carqueja

Browse every other medication we’ve checked against Carqueja — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Carqueja page.

No interaction 2,743 drugs checked — show the list

We also checked Carqueja against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Carqueja list.

See the full Carqueja interactions page
See every supplement checked against Mestranol, Norethynodrel, ranked by severity
Evidence & sources

Carqueja References

The 2 references that drive our Carqueja monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Coelho MG, Reis PA, Gava VB, et al. Anti-arthritic effect and subacute toxicological evaluation of Baccharis genistelloides aqueous extract. Toxicol Lett 2004;154:69-80. PubMed
  2. Oliveira AC, Endringer DC, Amorim LA, et al. Effect of the extracts and fractions of Baccharis trimera and Syzygium cumini on glycaemia of diabetic and non-diabetic mice. J Ethnopharmacol 2005;102:465-9. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Carqueja and Mestranol, Norethynodrel Together: Common Questions

Is it safe to take Carqueja with Mestranol, Norethynodrel?
We do not list a known interaction between Carqueja and Mestranol, Norethynodrel. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Carqueja and Mestranol, Norethynodrel combination checked?
Interactions in our licensed database are recorded against drug classes. Mestranol, Norethynodrel is filed under 5 classifications, and Carqueja has documented interactions with 1 drug class — none of Mestranol, Norethynodrel's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Carqueja interact with any other medications?
Yes. Carqueja has 86 documented drug interactions in our database — Mestranol, Norethynodrel is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mestranol, Norethynodrel interact with any supplements?
Yes. Mestranol, Norethynodrel has documented interactions with 188 supplements in our database — Carqueja is not one of them. The Mestranol, Norethynodrel interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Carqueja monograph Uses, safety profile, and every drug interaction in one place Mestranol, Norethynodrel supplement interactions Every supplement checked against Mestranol, Norethynodrel, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mestranol, Norethynodrel and Carqueja?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.