Drug & supplement interaction

Celery + Disulfiram

Disulfiram brand name: Antabuse.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Celery and Disulfiram in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Celery and Disulfiram

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Disulfiram and Celery in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Celery safety at a glance

Celery overall Use caution Generally safe as food, but concentrated supplements and allergy risk call for some caution.
Pregnancy Likely Unsafe When celery oil or seeds are used orally in larger amounts; celery might have uterine stimulant or abortifacient effects. Read the full pregnancy detail
Breastfeeding Use caution Not enough reliable information on celery supplements while breastfeeding, so it is best avoided.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Disulfiram and Celery? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Disulfiram

Interactions in our licensed database are recorded against drug classes, not just single drug names. Disulfiram is filed under 4 classifications — including cytochrome p450 2c9 (cyp2c9) inhibitors, seizure threshold lowering drugs, oral drugs. Celery has documented interactions with 8 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), antihypertensive drugs (moderate) and cytochrome p450 1a2 (cyp1a2) substrates (moderate) — and none of Disulfiram’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Celery Does Interact With Other Medications

Celery has 449 moderate, 202 minor known drug interactions in our database — Disulfiram isn’t one of them. If you take anything else, check it against the full list below.

Moderate 449 Minor 202 No known interaction 2,179 (incl. Disulfiram)
Taking anything else?

Check Another of Your Medications Against Celery

Covers the 2,830 medications we’ve checked against Celery. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Celery and Disulfiram May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Celery

    “Due to its psoralen content, contact with or ingestion of celery and exposure to ultraviolet radiation may cause photodermatitis (4,34347,40968,40969,40986,41085,41087,41143,41146,41151). Acute symptoms include skin eruption with edema and erythema; the main chronic symptom is hyperpigmentation at the eruption site.

    Celery can also cause contact or atopic dermatitis (19,41118,41124) and urticaria pigmentosa.”

    Celery · Natural Medicines adverse-effect record, reported in dermatitis.

    6 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 34347. Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water". Cutis 2002;70(1):29-30.
    3. 40968. DeLeo, V. A. Photocontact dermatitis. Dermatol Ther 2004;17(4):279-288. PubMed
    4. 40969. Groot, B. J., Belinfante-van Gelder, M. E., and Jans, H. W. [An epidemic of dermatitis caused by blanched celery]. Ned.Tijdschr.Geneeskd. 6-20-1992;136(25):1210-1213.
    5. 40986. Jeanmougin, M., Varroud-Vial, C., and Dubertret, L. [Phototoxic side-effect following celery ingestion during puvatherapy]. Ann.Dermatol Venereol 2005;132(6-7 Pt 1):566-567.
    6. 41085. Maso, M. J., Ruszkowski, A. M., Bauerle, J., DeLeo, V. A., and Gasparro, F. P. Celery phytophotodermatitis in a chef. Arch.Dermatol. 1991;127(6):912-913. DOI

    Disulfiram

    Listed in the ADVERSE REACTIONS section of the FDA label for Disulfiram. Read the label on DailyMed ›

Reported for Celery but not commonly for Disulfiram: a severe allergic reaction, mouth irritation or sores, shortness of breath and an allergic reaction.

Effects for Disulfiram come from the ADVERSE REACTIONS section of its FDA label; effects for Celery come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 1,124 voluntary FDA FAERS reports for Disulfiram that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Celery in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When celery oil or seeds are used orally in larger amounts; celery might have uterine stimulant or abortifacient effects.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Disulfiram Is Prescribed For, and What Celery Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Disulfiram is a prescription medicine with approved uses on its FDA label. Celery is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Disulfiram is prescribed for: Disulfiram is used as part of a treatment program for people with chronic alcoholism who want to stop drinking. It works by making the body react very unpleasantly to alcohol, which helps reinforce the commitment to stay sober. It is not a cure for alcoholism, and it works best when combined with counseling, motivation, and support. Used alone, without those supports, it is unlikely to make a lasting difference.

Celery has been studied for:

  • Headache studied, not established Celery has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Celery for headache

    Although there has been interest in using oral celery for headache, there is insufficient reliable information about the clinical effects of celery for this purpose.

  • Anxiety studied, not established Celery has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Celery for anxiety

    It is unclear if oral celery seed extract is beneficial in patients with anxiety.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Disulfiram on your own; if you are taking Celery for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Celery or Disulfiram

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Celery or Disulfiram, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Disulfiram

This page covers Celery only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Disulfiram page lists 45 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Bach Flower Remedies (major), Beer (major), Wine (major) and Biofeedback (moderate).

By severity: 4 major · 30 moderate · 11 minor.

Open the Disulfiram interaction page

One more smart check

Taking Celery as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,687 real supplement products containing Celery, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Celery. Even though Celery itself has no known interaction with Disulfiram, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Celery and Disulfiram Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Celery
Top 25%

#160 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Disulfiram
Steady interest

#1,462 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Celery reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Celery and Disulfiram records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Celery

What is Celery?

Celery
  • High blood pressure
  • Fluid retention (diuretic)
  • Joint pain and inflammation
  • Anxiety and sleep
  • Digestive support

Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort. Human evidence for these supplement uses is limited and mostly preliminary, so it should not replace proven treatments. Celery is generally safe as food, but concentrated supplements and possible allergic reactions warrant caution.

Apium graveolens · Apiaceae · Stalks, seeds, and seed oil (sometimes the whole plant and root) · Fresh vegetable, juice, seed powder, capsules, tablets, and seed oil extract

An interaction check asks whether these two react with each other — it does not ask whether Celery is a good idea for someone in your situation. Here is what our Celery record says about it on its own.

Celery: dosing

There is no official or well-established standardized dose for celery supplements. Products vary widely in strength, especially celery seed extracts and oils.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Celery monograph — the full record covers uses, side effects and every documented interaction.

Read the full Celery monograph & all interactions
Medication

About Disulfiram

What Is Disulfiram Used For?

Brand name: Antabuse

Disulfiram is used as part of a treatment program for people with chronic alcoholism who want to stop drinking. It works by making the body react very unpleasantly to alcohol, which helps reinforce the commitment to stay sober.

It is not a cure for alcoholism, and it works best when combined with counseling, motivation, and support. Used alone, without those supports, it is unlikely to make a lasting difference.

Most-Reported Side Effects for Disulfiram

From FAERS, the FDA’s public side-effect reporting system (1,124 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 83 reports
Toxicity to various agents 64 reports
Nausea 52 reports
Confusional state 48 reports
Drug abuse 44 reports
See full Disulfiram drug information
Keep checking

Other Drugs & Celery

Browse every other medication we’ve checked against Celery — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
449Moderate
202Minor
2,178No known interaction
449 Moderate 202 Minor 2,178 No interaction
Moderate

449 interactions

Showing 60 of 449 moderate interactions — see all 449 on the Celery page.

Minor

202 interactions

Showing 60 of 202 minor interactions — see all 202 on the Celery page.

No interaction 2,178 drugs checked — show the list

We also checked Celery against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,178 medications checked with no known interaction — see the full Celery list.

See the full Celery interactions page
See every supplement checked against Disulfiram, ranked by severity
Evidence & sources

Celery References

The 48 references that drive our Celery monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  5. Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
  6. Moses, G. Thyroxine interacts with celery seed tablets? Australian Prescriber 2001;24:6-7. DOI
  7. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  8. Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
  9. Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water". Cutis 2002;70(1):29-30.
  10. Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
  11. Rueff, F., Eberlein-Konig, B., and Przybilla, B. Oral hyposensitization with celery juice. Allergy 2001;56(1):82-83. PubMed
  12. Lombaert, G. A., Siemens, K. H., Pellaers, P., Mankotia, M., and Ng, W. Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. J AOAC Int 2001;84(4):1135-1143. DOI
  13. Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B., Luttkopf, D., Pompei, C., Wangorsch, A., Kastner, M., and Vieths, S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy PubMed
  14. Hoerler, S. and Ukiwe, J. Laryngeal edema from celery allergic reaction. Am.J.Emerg.Med. 1992;10(6):613. PubMed
  15. DeLeo, V. A. Photocontact dermatitis. Dermatol Ther 2004;17(4):279-288. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Celery and Disulfiram Together: Common Questions

Is it safe to take Celery with Disulfiram?
We do not list a known interaction between Celery and Disulfiram. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Celery and Disulfiram have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Celery and Disulfiram used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Celery in each. That is a conversation for your prescriber, especially if Disulfiram is being adjusted to a target.
How was the Celery and Disulfiram combination checked?
Interactions in our licensed database are recorded against drug classes. Disulfiram is filed under 4 classifications, and Celery has documented interactions with 8 drug classes — none of Disulfiram's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Celery interact with any other medications?
Yes. Celery has 651 documented drug interactions in our database — Disulfiram is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Disulfiram interact with any supplements?
Yes. Disulfiram has documented interactions with 45 supplements in our database — Celery is not one of them. The Disulfiram interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Celery monograph Uses, safety profile, and every drug interaction in one place Disulfiram drug information The full plain-English guide to this medication Disulfiram supplement interactions Every supplement checked against Disulfiram, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 48 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Disulfiram and Celery?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.