Drug & supplement interaction

Cereus + Hydrochlorothiazide, Labetalol

Hydrochlorothiazide, Labetalol brand name: Trandate HCT.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Cereus and Hydrochlorothiazide, Labetalol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Cereus and Hydrochlorothiazide, Labetalol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Hydrochlorothiazide, Labetalol and Cereus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Cereus safety at a glance

Cereus overall Use caution Limited safety data and possible effects on the heart make professional guidance important.
Pregnancy Avoid Not enough safety information; avoid during pregnancy.
Breastfeeding Avoid No reliable safety data, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Hydrochlorothiazide, Labetalol and Cereus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Hydrochlorothiazide, Labetalol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Hydrochlorothiazide, Labetalol is filed under 11 classifications — including beta-blockers, thiazide diuretics, diuretic drugs. Cereus has documented interactions with 2 drug classes — the most serious being digoxin (lanoxin) (moderate) and monoamine oxidase inhibitors (maois) (moderate) — and none of Hydrochlorothiazide, Labetalol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Cereus Does Interact With Other Medications

Cereus has 10 moderate known drug interactions in our database — Hydrochlorothiazide, Labetalol isn’t one of them. If you take anything else, check it against the full list below.

Moderate 10 No known interaction 2,820 (incl. Hydrochlorothiazide, Labetalol)
Taking anything else?

Check Another of Your Medications Against Cereus

Covers the 2,830 medications we’ve checked against Cereus. Pick one to open its full report.

What to actually watch for

What Cereus Itself Has Been Linked To

This is not an interaction — nothing below involves Hydrochlorothiazide, Labetalol. It is the side-effect record for Cereus on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Cereus, this list is the first place to look.

  • Itching / Diarrhea / Vomiting / Nausea Additional detail

    “Orally, fresh cereus juice may cause burning of the mouth, queasiness, nausea, vomiting, and diarrhea (4,18).

    Topically, it may cause itching and skin pustules (18).”

    Cereus · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Cereus — expand a row for the licensed statement it rests on. We haven’t matched Hydrochlorothiazide, Labetalol to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Hydrochlorothiazide, Labetalol.

Everything else you take

See Every Supplement That Interacts With Hydrochlorothiazide, Labetalol

This page covers Cereus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydrochlorothiazide, Labetalol page lists 265 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Beer (major).

By severity: 13 major · 228 moderate · 24 minor.

From our pharmacist’s overview on the Hydrochlorothiazide, Labetalol page

“Most people on Trandate HCT (hydrochlorothiazide with labetalol) are treating blood pressure for the long haul, often alongside calcium for bones or herbal wellness products, and that overlap is exactly where this list turns serious. Most of its 265 interacting ingredients either lower blood pressure beyond what was intended or pile on…”

Reviewed by 2 · Jul 18, 2026

Open the Hydrochlorothiazide, Labetalol interaction page

One more smart check

Taking Cereus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing Cereus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Cereus. Even though Cereus itself has no known interaction with Hydrochlorothiazide, Labetalol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Cereus and Hydrochlorothiazide, Labetalol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Cereus
Steady interest

#1,097 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Hydrochlorothiazide, Labetalol
Top 25%

#377 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Cereus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Cereus and Hydrochlorothiazide, Labetalol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Cereus

What is Cereus?

  • Heart palpitations
  • Mild heart symptoms
  • Anxiety and nervous tension
  • Shortness of breath
  • Fluid retention

Cereus (often called night-blooming cereus) is a cactus traditionally used in folk and homeopathic medicine for heart-related complaints like palpitations. High-quality human evidence supporting these uses is lacking, and because it may affect the heart, it should be used only under medical guidance. Pregnant and breastfeeding people should avoid it.

Selenicereus grandiflorus · Cactaceae · Flowers and young stems · Tincture, liquid extract, capsules, homeopathic preparations

An interaction check asks whether these two react with each other — it does not ask whether Cereus is a good idea for someone in your situation. Here is what our Cereus record says about it on its own.

Cereus: dosing

There is no established standard dose of Cereus. Products vary widely in strength, and homeopathic preparations are very different from herbal tinctures.If you choose to use a Cereus product, follow the directions on the label and do not exceed them.

From our Cereus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Cereus monograph & all interactions
Keep checking

Other Drugs & Cereus

Browse every other medication we’ve checked against Cereus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
10Moderate
0Minor
2,819No known interaction
10 Moderate 2,819 No interaction
Moderate

10 interactions

No interaction 2,819 drugs checked — show the list

We also checked Cereus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,819 medications checked with no known interaction — see the full Cereus list.

See the full Cereus interactions page
See every supplement checked against Hydrochlorothiazide, Labetalol, ranked by severity
Evidence & sources

Cereus References

The 3 references that drive our Cereus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Cereus and Hydrochlorothiazide, Labetalol Together: Common Questions

Is it safe to take Cereus with Hydrochlorothiazide, Labetalol?
We do not list a known interaction between Cereus and Hydrochlorothiazide, Labetalol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Cereus and Hydrochlorothiazide, Labetalol combination checked?
Interactions in our licensed database are recorded against drug classes. Hydrochlorothiazide, Labetalol is filed under 11 classifications, and Cereus has documented interactions with 2 drug classes — none of Hydrochlorothiazide, Labetalol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Cereus interact with any other medications?
Yes. Cereus has 10 documented drug interactions in our database — Hydrochlorothiazide, Labetalol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Hydrochlorothiazide, Labetalol interact with any supplements?
Yes. Hydrochlorothiazide, Labetalol has documented interactions with 265 supplements in our database — Cereus is not one of them. The Hydrochlorothiazide, Labetalol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Cereus monograph Uses, safety profile, and every drug interaction in one place Hydrochlorothiazide, Labetalol supplement interactions Every supplement checked against Hydrochlorothiazide, Labetalol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Hydrochlorothiazide, Labetalol and Cereus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.