Chenopodium Oil - Xifaxan (Rifaximin) Interaction
Herbal: Chenopodium Oil
Also Known As: Aceite de Paico, Aceite de Quenopodio, American Wormseed, Ansérine, Aritasou, Epazote, Épazote, Fausse Ambroisie, Goosefoot, Jesuit Tea, Mastruz, Mentrasto, Mentruco, Mexican Tea, Paico, Pazote, Thé du Mexique, Wormseed
Drug: Rifaximin
Brand names:
Xifaxan
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Rifaximin and Chenopodium Oil. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Chenopodium Oil Overview
Chenopodium oil is an essential oil extracted from the leaves and seeds of the Dysphania ambrosioides plant, which is also commonly known as Mexican tea and epazote. The oil is a pale yellow to green in color and has a strong, pungent smell.
Chenopodium oil has been used in traditional medicine for a variety of conditions, including respiratory problems, digestive issues, and skin conditions. Its most common use is as an anti-infective against roundworms and hookworms.
In general, the use of Chenopodium oil is not recommended, at least orally, as it contains ascaridole, which is toxic.
Rifaximin Overview
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Rifaximin 200-mg tablets are used to treat traveler's diarrhea caused by certain bacteria in adults and children at least 12 years of age. Rifaximin 550-mg tablets are used to prevent episodes of hepatic encephalopathy (changes in thinking, behavior, and personality caused by a build-up of toxins in the brain in people who have liver disease) in adults who have liver disease and to treat irritable bowel syndrome (with diarrhea) in adults. Rifaximin is in a class of medications called antibiotics. Rifaximin treats traveler's diarrhea and irritable bowel syndrome by stopping the growth of the bacteria that cause diarrhea. Rifaximin treats hepatic encephalopathy by stopping the growth of bacteria that produce toxins and that may worsen liver disease. Rifaximin will not work to treat traveler's diarrhea that is bloody or occurs with fever.
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Antibiotics such as rifaximin will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
Chenopodium Oil - More Interactions
Chenopodium Oil interacts with 333 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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