Drug & supplement interaction

Chickpea + Valproic Acid

Valproic Acid brand names: Depakene, Depacon, Valproate.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Chickpea and Valproic Acid in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Valproic Acid states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Chickpea and Valproic Acid

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Valproic Acid and Chickpea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Chickpea at all — not against Valproic Acid, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Chickpea safety at a glance

Chickpea overall Generally safe Chickpeas are a common, generally safe food for most people when cooked and eaten in normal amounts.
Pregnancy Likely Safe When used orally in amounts commonly found in food. There is insufficient reliable information available about the safety of chickpea for medicinal use in pregn... Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in amounts commonly found in food. There is insufficient reliable information available about the safety of chickpea for medicinal use in pregn... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Valproic Acid and Chickpea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Chickpea and Valproic Acid May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 3 of them are worth acting on rather than waiting out — marked below.

  • Shortness of breath / An allergic reaction Worth acting on Additional detail

    Chickpea

    “Chickpea is a common allergen. The most common symptoms of allergic reaction are respiratory and cutaneous and involve breathlessness, wheezing, urticaria, and angioedema.

    In some patients, chickpea can cause a severe allergic reaction with bronchial asthma or anaphylaxis. In a 17-year-old female, chickpea was the cause of a food-dependent exercise-induced anaphylaxis.”

    Chickpea · Natural Medicines adverse-effect record, reported in asthma.

    6 sources cited
    1. 719. Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
    2. 115085. García Ortiz JC, López-Asunsolo A, Cosmes P, Duran AM. Bronchial asthma induced by hypersensitivity to legumes. Allergol Immunopathol (Madr) 1995;23(1):38-40.
    3. 115086. Roberts H, Ben-Shoshan M. Food-dependent exercise-induced anaphylaxis to chickpea in a 17-year-old female: a case report. J Med Case Rep 2015;9:186. PubMed
    4. 115088. Dibek Misirlioglu E, Ozmen S, Bostanci I. An infant with chickpea and egg allergy. Allergol Immunopathol (Madr) 2011;39(3):186-7. PubMed
    5. 115089. Martin JA, Compaired JA, de la Hoz B, et al. Bronchial asthma induced by chick pea and lentil. Allergy 1992;47(2 Pt 2):185-7. PubMed
    6. 115090. Keskin O, Sekerel BE. Poppy seed allergy: a case report and review of the literature. Allergy Asthma Proc 2006;27(4):396-8. PubMed

    Valproic Acid

    Listed in the ADVERSE REACTIONS section of the FDA label for Valproic Acid. Read the label on DailyMed ›

  • A severe allergic reaction Worth acting on Additional detail

    Chickpea

    “Orally, chickpea is well tolerated when consumed in the amounts commonly found in food.

    Most Common Adverse Effects: Abdominal discomfort, bloating, and flatulence.

    Serious Adverse Effects (Rare): Anaphylaxis in susceptible individuals.”

    Chickpea · Natural Medicines adverse-effect record, reported in flatulence.

    Valproic Acid

    Listed in the ADVERSE REACTIONS section of the FDA label for Valproic Acid. Read the label on DailyMed ›

  • Bloating or gas / Stomach upset Additional detail

    Chickpea

    “Orally, flatulence, bloating, and abdominal discomfort have occurred rarely in clinical research.”

    Chickpea · Natural Medicines adverse-effect record, reported in flatulence.

    2 sources cited
    1. 115099. Pittaway JK, Ahuja KD, Cehun M, et al. Dietary supplementation with chickpeas for at least 5 weeks results in small but significant reductions in serum total and low-density lipoprotein cholesterols in adult women and men. Ann Nutr Metab 2006;50(6):512-8. PubMed
    2. 115112. Dahl WJ, Hanifi A, Zello GA, Tyler RT. Gastrointestinal tolerance to daily canned chickpea intake. Can J Diet Pract Res 2014;75(4):218-21. PubMed

    Valproic Acid

    Listed in the ADVERSE REACTIONS section of the FDA label for Valproic Acid. Read the label on DailyMed ›

Reported for Chickpea but not commonly for Valproic Acid: hives and wheezing.

Effects for Valproic Acid come from the ADVERSE REACTIONS section of its FDA label; effects for Chickpea come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 30,892 voluntary FDA FAERS reports for Valproic Acid that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Chickpea in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in amounts commonly found in food. There is insufficient reliable information available about the safety of chickpea for medicinal use in pregnancy and lactation; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Valproic Acid Products Have a Food Rule — Chickpea Should Not Break It

At least one FDA label for a product containing Valproic Acid says to take it with food. If you take Chickpea on an empty stomach out of habit, keep them separate — and take Valproic Acid with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Valproic Acid products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

irritation may benefit from administration of the drug with food or by slowly building up the dose from an initial low level.

From the Dosage and Administration section of the FDA label we read for Valproic Acid — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Chickpea or Valproic Acid

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chickpea or Valproic Acid, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Valproic Acid

This page covers Chickpea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Valproic Acid page lists 173 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Kava (major).

By severity: 9 major · 147 moderate · 17 minor.

From our pharmacist’s overview on the Valproic Acid page

“Anyone taking valproic acid (Depakene, Depacon) for seizures or bipolar disorder should treat this list with genuine care. Of the 173 supplements and herbs on file, nine are rated major.”

Reviewed by 2 · Jul 18, 2026

Open the Valproic Acid interaction page

How much people look this up

Where Chickpea and Valproic Acid Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chickpea
Steady interest

#1,261 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Valproic Acid
Top 25%

#497 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Chickpea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Chickpea and Valproic Acid records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Chickpea

What is Chickpea?

  • General nutrition and protein source
  • Blood sugar support
  • Cholesterol and heart health
  • Digestive and gut health (fiber)
  • Weight management and appetite control

Chickpeas are a nutritious food legume rich in protein, fiber, and various vitamins and minerals, and they fit well into a healthy diet. As a whole food they may support blood sugar, cholesterol, and digestive health, but they are not a proven treatment for any disease. People with legume allergies should avoid them, and anyone with specific health concerns should talk to a pharmacist or doctor.

Cicer arietinum · Fabaceae · Seeds (dried beans); sometimes sprouts and young leaves · Whole cooked beans, canned beans, flour (besan/gram flour), roasted snacks, hummus, sprouts, and protein powders

An interaction check asks whether these two react with each other — it does not ask whether Chickpea is a good idea for someone in your situation. Here is what our Chickpea record says about it on its own.

Chickpea: dosing

There is no official medicinal dose for chickpeas because they are a food. Most nutrition guidance simply encourages eating legumes regularly as part of a balanced diet.For chickpea flour, protein powders, or supplement products, there is no standardized dose.

From our Chickpea monograph — the full record covers uses, side effects and every documented interaction.

Read the full Chickpea monograph & all interactions
Medication

About Valproic Acid

What Is Valproic Acid Used For?

Brand names: Depakene, Depacon, Valproate

Valproic acid capsules (brands Valproic and Valproic Acid) and valproic acid oral solution (brand Valproic Acid) are both used to treat epilepsy. Specifically, they are approved for complex partial seizures (either alone or with other seizure types) as monotherapy or add-on therapy, and for simple and complex absence seizures as sole therapy or add-on therapy.

Both forms are intended for adults and pediatric patients. Always follow your prescriber's guidance on which product and regimen is right for you.

See full Valproic Acid drug information
Keep checking

Other Drugs & Chickpea

Browse every other medication we’ve checked against Chickpea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Chickpea against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Chickpea list.

See the full Chickpea interactions page
See every supplement checked against Valproic Acid, ranked by severity
Evidence & sources

Chickpea References

The 14 references that drive our Chickpea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
  2. García Ortiz JC, López-Asunsolo A, Cosmes P, Duran AM. Bronchial asthma induced by hypersensitivity to legumes. Allergol Immunopathol (Madr) 1995;23(1):38-40.
  3. Roberts H, Ben-Shoshan M. Food-dependent exercise-induced anaphylaxis to chickpea in a 17-year-old female: a case report. J Med Case Rep 2015;9:186. PubMed
  4. Dibek Misirlioglu E, Ozmen S, Bostanci I. An infant with chickpea and egg allergy. Allergol Immunopathol (Madr) 2011;39(3):186-7. PubMed
  5. Martin JA, Compaired JA, de la Hoz B, et al. Bronchial asthma induced by chick pea and lentil. Allergy 1992;47(2 Pt 2):185-7. PubMed
  6. Keskin O, Sekerel BE. Poppy seed allergy: a case report and review of the literature. Allergy Asthma Proc 2006;27(4):396-8. PubMed
  7. Pascual CY, Fernandez-Crespo J, Sanchez-Pastor S, et al. Allergy to lentils in Mediterranean pediatric patients. J Allergy Clin Immunol 1999;103(1 Pt 1):154-8. PubMed
  8. Kalogeromitros D, Armenaka M, Galatas I, Capellou O, Katsarou A. Anaphylaxis induced by lentils. Ann Allergy Asthma Immunol 1996;77(6):480-2. PubMed
  9. Branco Ferreira M, Pedro E, Meneses Santos J, et al. Latex and chickpea (Cicer arietinum) allergy: first description of a new association. Eur Ann Allergy Clin Immunol 2004;36(10):366-71. DOI
  10. Patil SP, Niphadkar PV, Bapat MM. Chickpea: a major food allergen in the Indian subcontinent and its clinical and immunochemical correlation. Ann Allergy Asthma Immunol 2001;87(2):140-5. PubMed
  11. Niphadkar PV, Patil SP, Bapat MM. Chickpea-induced anaphylaxis. Allergy 1997;52(1):115-6. PubMed
  12. Orhan F, Karakas T. Food-dependent exercise-induced anaphylaxis to lentil and anaphylaxis to chickpea in a 17-year-old boy. J Investig Allergol Clin Immunol 2008;18(6):465-8.
  13. Pittaway JK, Ahuja KD, Cehun M, et al. Dietary supplementation with chickpeas for at least 5 weeks results in small but significant reductions in serum total and low-density lipoprotein cholesterols in adult women and men. Ann Nutr Metab 2006;50(6):512-8. PubMed
  14. Dahl WJ, Hanifi A, Zello GA, Tyler RT. Gastrointestinal tolerance to daily canned chickpea intake. Can J Diet Pract Res 2014;75(4):218-21. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Chickpea and Valproic Acid Together: Common Questions

Is it safe to take Chickpea with Valproic Acid?
We do not list a known interaction between Chickpea and Valproic Acid. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Chickpea and Valproic Acid have any of the same side effects?
Yes — our sources link each of them separately to 5 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Chickpea and Valproic Acid at the same time of day?
At least one FDA label for a product containing Valproic Acid says to take it with food. If you take Chickpea on an empty stomach out of habit, keep them separate and take Valproic Acid with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Valproic Acid products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Valproic Acid interact with any supplements?
Yes. Valproic Acid has documented interactions with 173 supplements in our database — Chickpea is not one of them. The Valproic Acid interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Chickpea monograph Uses, safety profile, and every drug interaction in one place Valproic Acid drug information The full plain-English guide to this medication Valproic Acid supplement interactions Every supplement checked against Valproic Acid, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 14 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Valproic Acid and Chickpea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.