Drug & supplement interaction

Ecdysteroids + Ciclesonide

Ciclesonide brand names: Omnaris, Alvesco, Zetonna.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Ecdysteroids and Ciclesonide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Ecdysteroids and Ciclesonide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ciclesonide and Ecdysteroids in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ecdysteroids at all — not against Ciclesonide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ecdysteroids safety at a glance

Ecdysteroids overall Use caution Short-term use appears generally well tolerated in small studies, but long-term safety is not well established.
Pregnancy Avoid There is not enough safety information, so avoid use during pregnancy.
Breastfeeding Avoid There is not enough safety information, so avoid use while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ciclesonide and Ecdysteroids? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ciclesonide’s Own FDA Label Lists

This is not an interaction — none of it involves Ecdysteroids. These are the most notable effects listed in the ADVERSE REACTIONS section of Ciclesonide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 7 of them are worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on mentioned in 70.7% of FDA reports for Ciclesonide
  • Bone thinning Worth acting on
  • Chest pain Worth acting on
  • A severe allergic reaction Worth acting on
  • Hives Worth acting on
  • A higher chance of infection Worth acting on
  • An allergic reaction Worth acting on
  • Cough mentioned in 19.0% of FDA reports for Ciclesonide
  • Pain in an arm or leg
  • A stuffy or runny nose

Showing the 10 most notable of 18 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Ciclesonide. Read the label on DailyMed › Where a percentage is shown, it is the share of 13,541 voluntary FDA FAERS reports for Ciclesonide that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Ecdysteroids’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Ecdysteroids side to compare — that is a limit of the record, not a statement that Ecdysteroids has no side effects.

Everything else you take

See Every Supplement That Interacts With Ciclesonide

This page covers Ecdysteroids only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ciclesonide page lists 166 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Active Hexose Correlated Compound (ahcc) (moderate) and Adrafinil (moderate).

By severity: 2 major · 134 moderate · 30 minor.

From our pharmacist’s overview on the Ciclesonide page

“Ciclesonide (Alvesco, Omnaris, Zetonna) is a corticosteroid for asthma and nasal allergies, and even though it is inhaled rather than swallowed, its supplement list warrants genuine care. The body clears it through the CYP3A4 enzyme, and 121 of the 166 ingredients on file nudge that pathway one way or the other.”

Reviewed by 2 · Jul 18, 2026

Open the Ciclesonide interaction page

One more smart check

Taking Ecdysteroids as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Ecdysteroids, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ecdysteroids. Even though Ecdysteroids itself has no known interaction with Ciclesonide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Ecdysteroids and Ciclesonide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ecdysteroids
Steady interest

#1,315 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Ciclesonide
Top 25%

#501 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Ecdysteroids is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ecdysteroids reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Ecdysteroids and Ciclesonide records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ecdysteroids

What is Ecdysteroids?

  • Muscle building and strength
  • Athletic performance and recovery
  • General "adaptogen" or vitality support
  • Anti-aging and wellness

Ecdysteroids are plant- and insect-derived steroid-like compounds (most notably 20-hydroxyecdysone) marketed mainly to athletes for building muscle. Human evidence is very limited and far weaker than the marketing suggests, and long-term safety is not well studied. Talk to your pharmacist or doctor before using them, and avoid use during pregnancy and breastfeeding.

Roots and aerial parts of certain plants (such as Rhaponticum carthamoides and Spinacia oleracea); also found in some insects · Capsules, tablets, powders, and extracts (often standardized to 20-hydroxyecdysone)

An interaction check asks whether these two react with each other — it does not ask whether Ecdysteroids is a good idea for someone in your situation. Here is what our Ecdysteroids record says about it on its own.

Ecdysteroids: dosing

There is no well-established, standardized dose for ecdysteroids. Doses used in research vary, and many products are standardized to a percentage of 20-hydroxyecdysone, but ideal amounts in people are not proven.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Ecdysteroids monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ecdysteroids monograph & all interactions
Medication

About Ciclesonide Oral Inhalation

What Is Ciclesonide Oral Inhalation Used For?

Brand names: Omnaris, Alvesco, Zetonna

Alvesco (ciclesonide oral inhalation) is used for maintenance treatment of asthma. It is a preventive medicine for adults and teens 12 years of age and older.

It is not a rescue inhaler. It does not relieve sudden breathing trouble (acute bronchospasm) and is not indicated for children under 12.

Most-Reported Side Effects for Ciclesonide

From FAERS, the FDA’s public side-effect reporting system (13,541 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Asthma 5,858 reports
Dyspnea 4,621 reports
Wheezing 3,710 reports
Therapeutic product effect incomplete 2,598 reports
Cough 2,578 reports
See full Ciclesonide Oral Inhalation drug information Ciclesonide NDC codes and packages
Keep checking

Other Drugs & Ecdysteroids

Browse every other medication we’ve checked against Ecdysteroids — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Ecdysteroids References

The 2 sources that drive our Ecdysteroids monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Ecdysteroids is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  2. Dietary Supplements — MedlinePlus Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ecdysteroids and Ciclesonide Together: Common Questions

Is it safe to take Ecdysteroids with Ciclesonide?
We do not list a known interaction between Ecdysteroids and Ciclesonide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Ciclesonide interact with any supplements?
Yes. Ciclesonide has documented interactions with 166 supplements in our database — Ecdysteroids is not one of them. The Ciclesonide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Ciclesonide and Ecdysteroids?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.