Drug & supplement interaction

Elecampane + Carbinoxamine Maleate

Carbinoxamine Maleate brand name: Karbinal ER.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Elecampane and Carbinoxamine Maleate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Elecampane and Carbinoxamine Maleate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Carbinoxamine Maleate and Elecampane in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elecampane safety at a glance

Elecampane overall Use caution Generally used in small amounts in tea and tinctures, but it can cause allergic reactions and stomach upset.
Pregnancy Likely Unsafe When used orally; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Carbinoxamine Maleate and Elecampane? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Carbinoxamine Maleate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Carbinoxamine Maleate is filed under 2 classifications — anticholinergic drugs, oral drugs. Elecampane has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Carbinoxamine Maleate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Elecampane Does Interact With Other Medications

Elecampane has 248 moderate known drug interactions in our database — Carbinoxamine Maleate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Elecampane

Covers the 2,830 medications we’ve checked against Elecampane. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Elecampane and Carbinoxamine Maleate May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Diarrhea / Vomiting Additional detail

    Elecampane

    “Orally, large doses of elecampane may cause vomiting and diarrhea (12).”

    Elecampane · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

    Carbinoxamine Maleate

    Listed in the ADVERSE REACTIONS section of the FDA label for Carbinoxamine Maleate. Read the label on DailyMed ›

  • A skin rash Additional detail

    Elecampane

    “Topically, elecampane can cause allergic contact dermatitis, especially in individuals sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many other herbs.”

    Elecampane · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 6958. Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
    2. 48729. Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
    3. 48731. Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed

    Carbinoxamine Maleate

    Listed in the ADVERSE REACTIONS section of the FDA label for Carbinoxamine Maleate. Read the label on DailyMed ›

Effects for Carbinoxamine Maleate come from the ADVERSE REACTIONS section of its FDA label; effects for Elecampane come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 190 voluntary FDA FAERS reports for Carbinoxamine Maleate that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Elecampane in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Carbinoxamine Maleate

This page covers Elecampane only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Carbinoxamine Maleate page lists 46 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), Angel's Trumpet (moderate) and Bacopa (moderate).

By severity: 3 major · 32 moderate · 11 minor.

Open the Carbinoxamine Maleate interaction page

One more smart check

Taking Elecampane as Part of a Dietary Supplement Product? Check It for Interactions

We hold 332 real supplement products containing Elecampane, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Elecampane. Even though Elecampane itself has no known interaction with Carbinoxamine Maleate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Elecampane and Carbinoxamine Maleate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elecampane
Top half

#434 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Carbinoxamine Maleate
Top half

#1,273 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elecampane reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Elecampane and Carbinoxamine Maleate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Elecampane

What is Elecampane?

Elecampane
  • Cough and bronchitis
  • Asthma symptoms
  • Loosening mucus (expectorant)
  • Digestive upset
  • Intestinal worms (traditional)

Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Inula helenium · Asteraceae · Roots and rhizomes · Tea, tincture, dried root, capsules, lozenges, syrup

An interaction check asks whether these two react with each other — it does not ask whether Elecampane is a good idea for someone in your situation. Here is what our Elecampane record says about it on its own.

Elecampane: dosing

There is no standardized, well-established dose for elecampane. It is commonly taken as a tea made from the dried root, as a tincture, or in syrups and lozenges, with the amount varying by product and tradition.Because the strength of products varies and reliable dosing studies are lacking, the safest approach is to follow the directions on the product label and start with a small amount.

From our Elecampane monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elecampane monograph & all interactions
Medication

About Carbinoxamine Maleate

Most-Reported Side Effects for Carbinoxamine Maleate

From FAERS, the FDA’s public side-effect reporting system (190 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Drug toxicity 14 reports
Headache 14 reports
Sinusitis 10 reports
Fever 9 reports
Fatigue 8 reports
Keep checking

Other Drugs & Elecampane

Browse every other medication we’ve checked against Elecampane — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Elecampane page.

No interaction 2,581 drugs checked — show the list
Evidence & sources

Elecampane References

The 5 references that drive our Elecampane monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
  4. Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
  5. Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elecampane and Carbinoxamine Maleate Together: Common Questions

Is it safe to take Elecampane with Carbinoxamine Maleate?
We do not list a known interaction between Elecampane and Carbinoxamine Maleate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Elecampane and Carbinoxamine Maleate have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Elecampane and Carbinoxamine Maleate combination checked?
Interactions in our licensed database are recorded against drug classes. Carbinoxamine Maleate is filed under 2 classifications, and Elecampane has documented interactions with 1 drug class — none of Carbinoxamine Maleate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Elecampane interact with any other medications?
Yes. Elecampane has 248 documented drug interactions in our database — Carbinoxamine Maleate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Carbinoxamine Maleate interact with any supplements?
Yes. Carbinoxamine Maleate has documented interactions with 46 supplements in our database — Elecampane is not one of them. The Carbinoxamine Maleate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Carbinoxamine Maleate and Elecampane?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.