Medication interaction hub

What Supplements Interact with Carbinoxamine Maleate?

Carbinoxamine Maleate brand name: Karbinal ER. Every interaction below applies to the brands too.

46 Interactions 3 Major 32 Moderate 11 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Carbinoxamine Maleate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Carbinoxamine Maleate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

46 supplements and herbal ingredients have interactions with Carbinoxamine Maleate on file in the HelloPharmacist interaction database — 3 rated major, 32 moderate, and 11 minor. The most serious involve Activated Charcoal, Henbane and Scopolia.

Our assessment: with 3 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Carbinoxamine Maleate.

Major 3 Moderate 32 Minor 11 No known interaction 1,406

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Carbinoxamine Maleate: Top Interactions at a Glance

The Carbinoxamine Maleate supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 46 interacting ingredients — plus 1,406 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Carbinoxamine Maleate Combinations Today

The Carbinoxamine Maleate + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Angel's Trumpet + Carbinoxamine Maleatei

Concomitant use may increase anticholinergic effects and adverse effects.

Read the full interaction Moderate Likelihood Possible Tragacanth + Carbinoxamine Maleatei

Theoretically, tragacanth might alter absorption of oral drugs.

Read the full interaction Minor Likelihood Unlikely Deanol + Carbinoxamine Maleatei

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.

Read the full interaction Moderate Likelihood Probable Datura Wrightii + Carbinoxamine Maleatei

Datura wrightii contains atropine and scopolamine, as well as other tropane alkaloids with anticholinergic activity.

Read the full interaction Major Likelihood Probable Activated Charcoal + Carbinoxamine Maleatei

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.

Read the full interaction Major Likelihood Probable Henbane + Carbinoxamine Maleatei

Concomitant use of henbane can have additive anticholinergic effects and adverse effects with amantadine, antihistamines, atropine, belladonna alkaloids, hyoscy...

Read the full interaction
The complete list

Every Supplement Checked Against Carbinoxamine Maleate

All 1,452 ingredients in our database, ranked by severity — 46 with a Carbinoxamine Maleate interaction on file and 1,406 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Carbinoxamine Maleate?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Angel's Trumpet with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Concomitant use may increase anticholinergic effects and adverse effects.

Full Angel's Trumpet + Carbinoxamine Maleate answer

Can you take Tragacanth with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.

Full Tragacanth + Carbinoxamine Maleate answer

Can you take Deanol with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.

Full Deanol + Carbinoxamine Maleate answer

Can you take Datura Wrightii with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Datura wrightii contains atropine and scopolamine, as well as other tropane alkaloids with anticholinergic activity.

Full Datura Wrightii + Carbinoxamine Maleate answer

Can you take Purple Nut Sedge with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro, purple nut sedge dose-dependently inhibits acetylcholinesterase (AChE).

Full Purple Nut Sedge + Carbinoxamine Maleate answer

Can you take Sage with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, sage might decrease the clinical effects of anticholinergic drugs.

Full Sage + Carbinoxamine Maleate answer

Can you take Slippery Elm with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Carbinoxamine Maleate answer

Can you take Syrian Rue with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Syrian rue might decrease the effects of anticholinergic drugs.

Full Syrian Rue + Carbinoxamine Maleate answer

Can you take Teazle with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro research suggests that teazle extract can inhibit acetylcholinesterase activity.

Full Teazle + Carbinoxamine Maleate answer

Can you take Thyme with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use of anticholinergic drugs and thyme essential oil might reduce the effects of anticholinergic drugs.

Full Thyme + Carbinoxamine Maleate answer

Can you take Toothed Clubmoss with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopol...

Full Toothed Clubmoss + Carbinoxamine Maleate answer

Can you take Wild Lettuce with Carbinoxamine Maleate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Studies report varying evidence on whether or not wild lettuce contains hyoscyamine, an anticholinergic drug.

Full Wild Lettuce + Carbinoxamine Maleate answer

Can you take Thyroid Extract with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Food and medications can interfere with thyroid hormone absorption.

Full Thyroid Extract + Carbinoxamine Maleate answer

Can you take Agar with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.

Full Agar + Carbinoxamine Maleate answer

Can you take Algin with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, algin can alter the absorption of oral drugs.

Full Algin + Carbinoxamine Maleate answer

Can you take Black Psyllium with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Full Black Psyllium + Carbinoxamine Maleate answer

Can you take Blond Psyllium with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.

Full Blond Psyllium + Carbinoxamine Maleate answer

Can you take Carob with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, carob might also impair the absorption of oral drugs.

Full Carob + Carbinoxamine Maleate answer

Can you take Karaya Gum with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...

Full Karaya Gum + Carbinoxamine Maleate answer

Can you take Marshmallow with Carbinoxamine Maleate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.

Full Marshmallow + Carbinoxamine Maleate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Carbinoxamine Maleate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Carbinoxamine Maleate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Carbinoxamine Maleate sits in 2 interaction categories. Open any one to see what the group means:

Anticholinergic Drugs 30 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

30 of the supplement ingredients on this page reach Carbinoxamine Maleate through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Carbinoxamine Maleate through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Carbinoxamine Maleate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Carbinoxamine Maleate.

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Products that contain Carbinoxamine Maleate-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Carbinoxamine Maleate.

Calmhills by Herbal Hills contains Henbane Migrahills by Herbal Hills contains Henbane Migrahills by Herbal Hills contains Henbane Migrahills by Herbal Hills contains Henbane Angiplex by UNDA Plex contains Belladonna Back & Neck Pain by BIOVEA Homeopathics contains Belladonna SuperFlex-H by NewtonEverett contains Belladonna CBD+13 by T-Relief contains Belladonna
Pharmacist Counseling Corner

Carbinoxamine Maleate & Supplements: Common Questions

What supplements interact with Carbinoxamine Maleate?
More than you might expect — 46 in total, though they are far from equal: 3 are rated major, 32 moderate, and 11 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Activated Charcoal, Henbane, Scopolia.
Which Carbinoxamine Maleate supplement interactions are the most serious?
Focus on the major group: Activated Charcoal, Henbane and Scopolia. A major rating means the combination can be clinically significant, not that harm is guaranteed — but it's exactly the kind of thing to run past your pharmacist before your next dose, not after. Jump to the ranked list.
Can I take vitamins or supplements while on Carbinoxamine Maleate?
Usually yes — most people on Carbinoxamine Maleate can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Karbinal ER have the same supplement interactions as Carbinoxamine Maleate?
Yes — Karbinal ER all contain Carbinoxamine Maleate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Carbinoxamine Maleate and my other medications?
This page covers Carbinoxamine Maleate against supplements and herbal ingredients. Checking Carbinoxamine Maleate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.