Ergot + Collagenase Clostridium Histolyticum-Aaes
Collagenase Clostridium Histolyticum-Aaes brand name: Qwo.
We found no known interaction between Ergot and Collagenase Clostridium Histolyticum-Aaes in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Ergot and Collagenase Clostridium Histolyticum-Aaes
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Collagenase Clostridium Histolyticum-Aaes and Ergot in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Ergot safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Ergot Does Interact With Other Medications
Ergot has 462 moderate known drug interactions in our database — Collagenase Clostridium Histolyticum-Aaes isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Ergot
We haven’t checked that one against Ergot yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Ergot. Pick one to open its full report.
Ergot in Pregnancy & Breastfeeding
When used orally due to risk for toxicity and stillbirth; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Where Ergot and Collagenase Clostridium Histolyticum-Aaes Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#858 of 1,452 supplements looked up here in the last 7 days
#180 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ergot reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Ergot and Collagenase Clostridium Histolyticum-Aaes records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Ergot
What is Ergot?
- Heavy menstrual or uterine bleeding
- Bleeding after childbirth
- Migraine headaches
- Stimulating uterine contractions
Ergot is a toxic fungus that grows on rye and contains powerful chemicals (ergot alkaloids) that strongly narrow blood vessels and squeeze the uterus. Because raw ergot is poisonous and the dose is impossible to control safely, it should never be used as a home remedy or supplement. Some purified ergot chemicals are used as prescription drugs under strict medical supervision, but the crude herb is not safe to take.
Claviceps purpurea · Clavicipitaceae · The fungal mass (sclerotium) that grows on rye and other grasses · Historically used as crude dried fungus; purified ergot alkaloids are available only as prescription medicines (not as a dietary supplement)
An interaction check asks whether these two react with each other — it does not ask whether Ergot is a good idea for someone in your situation. Here is what our Ergot record says about it on its own.
Ergot: dosing
There is no safe established dose of crude ergot for self-care, and it should not be taken as a supplement. The amount of active chemical in the raw fungus varies and cannot be measured reliably at home, which makes poisoning very easy.The only safe way ergot chemicals are used is as purified, carefully measured prescription medicines given and monitored by a healthcare professional. Do not try to make or take any ergot preparation on your own.
From our Ergot monograph — the full record covers uses, side effects and every documented interaction.
About Collagenase Clostridium histolyticum Injection
What Is Collagenase Clostridium histolyticum Injection Used For?
Brand name: Qwo
-
Collagenase Clostridium histolyticum injection (Xiaflex) is used to treat Dupuytren's contracture (a painless thickening and tightening of tissue [cord] beneath the skin in the palm of the hand, which may make it difficult to straighten one or more fingers) when a cord of tissue can be felt upon examination. Collagenase Clostridium histolyticum injection (Xiaflex) is also used to treat Peyronie's disease (a thickening of tissue [plaque] inside the penis that causes the penis to curve). Collagenase Clostridium histolyticum injection (QWO) is also used to treat cellulite (fat deposit beneath the skin) in the buttocks of adult women. Collagenase Clostridium histolyticum injection is in a class of medications called enzymes. In people with Dupuytren's contracture, it works by helping to break down the cord of thickened tissue and allows the finger(s) to be straightened. In people with Peyronie's disease, it works by helping to break down the plaque of thickened tissue and allows the penis to be straightened. In women with cellulite, it works by releasing fibrous bands, redistributing fat cells, and stimulating the growth of new collagen.
Other Drugs & Ergot
Browse every other medication we’ve checked against Ergot — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
462 interactions
- Diltiazem ›
- Nifedipine ›
- Metronidazole ›
- Phentermine ›
- Methylphenidate ›
- Erythromycin ›
- Estradiol ›
- Norethindrone ›
- Verapamil ›
- Phenylpropanolamine ›
- Prednisone ›
- Cyclosporine ›
- Ciprofloxacin ›
- Fentanyl ›
- Nicotine ›
- Carbamazepine ›
- Dextromethorphan ›
- Miconazole ›
- Phenylephrine ›
- Pseudoephedrine ›
- Trimipramine ›
- Amphetamine ›
- Buprenorphine ›
- Diethylpropion ›
- Everolimus ›
- Nortriptyline ›
- Selegiline ›
- Sumatriptan Succinate ›
- Aripiprazole ›
- Caffeine (otc Drug) ›
- Cimetidine ›
- Cyclobenzaprine ›
- Desipramine ›
- Doxepin ›
- Duloxetine ›
- Erythromycin Ethylsuccinate ›
- Erythromycin Stearate ›
- Isoniazid ›
- Itraconazole ›
- Metoclopramide ›
- Modafinil ›
- Nicardipine ›
- Oxymetazoline Hydrochloride ›
- Paroxetine ›
- Prucalopride ›
- Tramadol ›
- Valproic Acid ›
- Vortioxetine ›
- Almotriptan ›
- Amiodarone ›
- Amphetamine Sulfate ›
- Aprepitant ›
- Aripiprazole Lauroxil ›
- Caffeine (prescription Drug) ›
- Chlorpheniramine ›
- Clarithromycin ›
- Clozapine ›
- Cocaine Hydrochloride (prescription Drug) ›
- Danazol ›
- Desvenlafaxine ›
Showing 60 of 462 moderate interactions — see all 462 on the Ergot page.
No interaction 2,367 drugs checked — show the list
We also checked Ergot against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Testosterone ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Isotretinoin ›
- Tirzepatide ›
- Warfarin Sodium ›
- Ibuprofen ›
- Amlodipine Besylate ›
- Docusate ›
- Valacyclovir ›
- Tadalafil ›
- Hydroxyurea ›
- Metformin ›
- Semaglutide ›
- Propranolol ›
- Amoxicillin ›
- Methotrexate ›
- Levothyroxine, Liothyronine ›
- Lisinopril ›
- Bupropion ›
- Bendamustine ›
- Azithromycin ›
- Pregabalin ›
- Doxycycline ›
- Gabapentin ›
- Lamotrigine ›
- Acyclovir ›
- Naproxen ›
- Clonazepam ›
- Omeprazole ›
- Letrozole ›
- Acetaminophen, Codeine ›
- Candesartan Cilexetil ›
- Amoxicillin, Clavulanate Potassium ›
- Bisoprolol ›
- Acetylsalicylic Acid ›
- Acetaminophen, Aspirin ›
- Amlodipine Besilate ›
- Acetaminophen, Oxycodone ›
- Diazepam ›
- Perindopril Arginine, Amlodipine ›
- Calcium Oxybate, Magnesium Oxybate, Potassium Oxybate, Sodium Oxybate ›
- Insulin Degludec, Liraglutide ›
- Ezetimibe ›
- Dapsone ›
- Amlodipine Besylate, Benazepril ›
- Cephalexin ›
- Cyclopentolate ›
Showing the 60 most looked-up of 2,367 medications checked with no known interaction — see the full Ergot list.
Ergot References
The 4 references that drive our Ergot monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
- Singhal AB, Caviness VS, Begleiter AF, et al. Cerebral vasoconstriction and stroke after use of serotonergic drugs. Neurology 2002;58:130-3. PubMed
- Eadie MJ. Convulsive ergotism: epidemics of the serotonin syndrome? Lancet Neurol 2003;2:429-34. PubMed
- Etzel RA. Mycotoxins. JAMA 2002;287:425-7.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Ergot and Collagenase Clostridium Histolyticum-Aaes Together: Common Questions
Is it safe to take Ergot with Collagenase Clostridium Histolyticum-Aaes?
Does Ergot interact with any other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.