Drug & supplement interaction

Fish Oil + Ivermectin

Ivermectin brand names: Stromectol, Mectizan, Sklice, Soolantra.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 13, 2026

The bottom line No known interaction

We found no known interaction between Fish Oil and Ivermectin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ivermectin states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Fish Oil and Ivermectin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Ivermectin and Fish Oil in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Fish Oil safety at a glance

Fish Oil overall Generally safe Fish oil is generally well tolerated for most adults at typical supplement doses.

Pregnancy Likely Safe When used orally and appropriately. Intake of fish oil during pregnancy does not appear to adversely affect the fetus or nursing infant. One large clinical tria... Read the full pregnancy detail

Breastfeeding Likely Safe When used orally and appropriately. Intake of fish oil during pregnancy does not appear to adversely affect the fetus or nursing infant. One large clinical tria... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Ivermectin and Fish Oil? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Ivermectin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Ivermectin is filed under 4 classifications — including topical drugs, p-glycoprotein substrates, oral drugs. Fish Oil has documented interactions with 9 drug classes — the most serious being antihypertensive drugs (moderate), contraceptive drugs (moderate) and cyclosporine (neoral, sandimmune) (moderate) — and none of Ivermectin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Fish Oil Does Interact With Other Medications

Fish Oil has 207 moderate, 120 minor known drug interactions in our database — Ivermectin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 207 Minor 120 No known interaction 2,503 (incl. Ivermectin)

Taking anything else?

Check Another of Your Medications Against Fish Oil

Covers the 2,830 medications we’ve checked against Fish Oil. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Fish Oil and Ivermectin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 3 of them are worth acting on rather than waiting out — marked below.

Wheezing Worth acting on Additional detail
Fish Oil
“Orally, fish oil has been reported to cause nasopharyngitis and upper respiratory tract infections in 3.3% of patients in one clinical trial. Exacerbation of asthma and apnea have been reported for patients using fish oil.”

Fish Oil · Natural Medicines adverse-effect record, reported in asthma.
5 sources cited

65798. Davidson, M. H., Stein, E. A., Bays, H. E., Maki, K. C., Doyle, R. T., Shalwitz, R. A., Ballantyne, C. M., and Ginsberg, H. N. Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patie

1040. Hawthorne AB, Daneshmend TK, Hawkey CJ, et al. Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial. Gut 1992;33:922-8. PubMed

66061. Turner, D., Shah, P. S., Steinhart, A. H., Zlotkin, S., and Griffiths, A. M. Maintenance of remission in inflammatory bowel disease using omega-3 fatty acids (fish oil): a systematic review and meta-analyses. Inflamm.Bowel.Dis. 2011;17(1):336-345. PubMed

66119. Oliver, C. and Jahnke, N. Omega-3 fatty acids for cystic fibrosis. Cochrane.Database.Syst.Rev. 2011;(8):CD002201. PubMed

66354. Lawrence, R. and Sorrell, T. Eicosapentaenoic acid in cystic fibrosis: evidence of a pathogenetic role for leukotriene B4. Lancet 8-21-1993;342(8869):465-469. PubMed
Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin. Read the label on DailyMed ›
Anemia Worth acting on Additional detail
Fish Oil
“Orally, 3 grams or greater of omega-3 fatty acids daily may inhibit platelet aggregation and increase the risk of bleeding; however, there is little evidence of statistically significant bleeding risk at lower doses.”

Fish Oil · Natural Medicines adverse-effect record, reported in anemia.
6 sources cited

1313. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference

8699. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed

66500. Knapp, H. R. Dietary fatty acids in human thrombosis and hemostasis. Am J Clin Nutr 1997;65(5 Suppl):1687S-1698S. PubMed

66501. Archer, S. L., Green, D., Chamberlain, M., Dyer, A. R., and Liu, K. Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study. Arterioscler Thromb.Vasc.Biol 1998;1 PubMed

66334. Weksler, B. B. Omega 3 fatty acids have multiple antithrombotic effects. World Rev Nutr Diet 1994;76:47-50. PubMed

101543. McNamara RK, Strawn JR, Tallman MJ, et al. Effects of fish oil monotherapy on depression and prefrontal neurochemistry in adolescents at high risk for bipolar I disorder: A 12-week placebo-controlled proton magnetic resonance spectroscopy trial. J Child A PubMed
Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin. Read the label on DailyMed ›
Bleeding or bruising Worth acting on Additional detail

Fish Oil

“Orally and parenterally, fish oil is generally well-tolerated. Topically, no adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted.

Most Common Adverse Effects:

Orally: Abdominal pain, bad breath, fishy aftertaste, heartburn, increased low-density lipoprotein (LDL) cholesterol levels, loose stools, nausea, and rash.

Serious Adverse Effects (Rare):

Orally: Atrial…”

Fish Oil · Natural Medicines adverse-effect record, reported in atrial fibrillation.

Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin. Read the label on DailyMed ›
Itching reported in 6.2% of FDA reports for Ivermectin Additional detail
Fish Oil
“Orally, skin rashes, itching, and skin irritation have been reported.

A case of severe tissue inflammation and breast tissue necrosis has been reported for a female who injected fish oil from capsules subcutaneously for breast augmentation.”

Fish Oil · Natural Medicines adverse-effect record, reported in skin irritation.
6 sources cited

66498. Kuenzel U and Bertsch S. Clinical experiences with a standardized commercial fish oil product containing 33.5% omega-3 fatty acids - field trial with 3958 hyperlipemic patients in general practitioner practice. In: Chandra RK. Health Effects of Fish and F

66492. Sydenham E, Dangour AD Lim WS. Omega 3 fatty acid for the prevention of cognitive decline and dementia. Cochrane Database Syst Rev. 2012;6:CD005379. PubMed

66488. Schachter, HM, Reisman, J, Tran, K, Dales, B, Kourad, K, Barnes, D, Sampson, M, Morrison, A, Gaboury, I, and Blackman, J. Health effects of omega-3 fatty acids on asthma. Evid.Rep.Technol.Assess.(Summ.) 2004;(91):1-7.

89369. Souied EH, Delcourt C, Querques G, Bassols A, Merle B, Zourdani A, Smith T, Benlian P; Nutritional AMD Treatment 2 Study Group. Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: the Nutritional AMD Treatment 2 stud DOI

104551. Suradom C, Suttajit S, Oon-Arom A, Maneeton B, Srisurapanont M. Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation for prevention and treatment of perinatal depression: a systematic review and meta-analysis of randomized-controlled trials. Nord PubMed

89371. Turk E, Karagulle E, Koksal H, Togan T, Erinanc OH, Dogru O, Moray G. Bilateral breast necrosis due to local injection of fish oil. Breast J 2013;19(2):196-8. PubMed
Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›
Reduced appetite / Constipation Additional detail
Fish Oil
“Orally, most adverse effects of omega-3 fatty acids are gastrointestinal in nature. Gastrointestinal upset is common with the use of fish oil supplements, occurring in up to 5% of patients in clinical trials, with nausea in up to 1.5% of patients. Diarrhea and loose stools may also occur, with potentially severe diarrhea at very high doses.”

Fish Oil · Natural Medicines adverse-effect record, reported in anorexia.
6 sources cited

12915. Wang C, Chung M, Lichtenstein A, et al. Effects of omega-3 fatty acids on cardiovascular disease. Evid Rep Technol Assess (Summ) 2004 Mar;(94):1-8.

65599. Maclean, C. H., Mojica, W. A., Morton, S. C., Pencharz, J., Hasenfeld, Garland R., Tu, W., Newberry, S. J., Jungvig, L. K., Grossman, J., Khanna, P., Rhodes, S., and Shekelle, P. Effects of omega-3 fatty acids on lipids and glycemic control in type II di

65728. Reisman, J., Schachter, H. M., Dales, R. E., Tran, K., Kourad, K., Barnes, D., Sampson, M., Morrison, A., Gaboury, I., and Blackman, J. Treating asthma with omega-3 fatty acids: where is the evidence? A systematic review. BMC.Complement Altern Med 2006;6 PubMed

65770. Lim, A. K., Manley, K. J., Roberts, M. A., and Fraenkel, M. B. Fish oil for kidney transplant recipients. Cochrane Database Syst Rev 2007;(2):CD005282. DOI

65780. Freund-Levi, Y., Basun, H., Cederholm, T., Faxen-Irving, G., Garlind, A., Grut, M., Vedin, I., Palmblad, J., Wahlund, L. O., and Eriksdotter-Jonhagen, M. Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptom

65904. Turnbull, T., Cullen-Drill, M., and Smaldone, A. Efficacy of omega-3 fatty acid supplementation on improvement of bipolar symptoms: a systematic review. Arch Psychiatr.Nurs 2008;22(5):305-311. PubMed
Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin. Read the label on DailyMed ›
Stomach pain Additional detail

Fish Oil

Recorded for Fish Oil in the same Natural Medicines adverse-effect record shown under Bleeding or bruising above.

Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin. Read the label on DailyMed ›
Headache / Dizziness reported in 10.3% of FDA reports for Ivermectin Additional detail
Fish Oil
“Orally, fish oil may cause headache, dizziness, and inability to sleep. Also, restlessness and formication have been reported in less than 1% of studied cases of patients taking fish oil.”

Fish Oil · Natural Medicines adverse-effect record, reported in cluster headache.
6 sources cited

65599. Maclean, C. H., Mojica, W. A., Morton, S. C., Pencharz, J., Hasenfeld, Garland R., Tu, W., Newberry, S. J., Jungvig, L. K., Grossman, J., Khanna, P., Rhodes, S., and Shekelle, P. Effects of omega-3 fatty acids on lipids and glycemic control in type II di

65648. Schachter, H. M., Kourad, K., Merali, Z., Lumb, A., Tran, K., and Miguelez, M. Effects of omega-3 fatty acids on mental health. Evid.Rep.Technol.Assess.(Summ.) 2005;(116):1-11.

89359. Oliveira JM, Rondó PH, Yudkin JS, Souza JM, Pereira TN, Catalani AW, Picone CM, Segurado AA. Effects of fish oil on lipid profile and other metabolic outcomes in HIV-infected patients on antiretroviral therapy: a randomized placebo-controlled trial. Int J PubMed

103491. Nicholls SJ, Lincoff AM, Garcia M, et al. Effect of high-dose omega-3 fatty acids vs corn oil on major adverse cardiovascular events in patients at high cardiovascular risk: The STRENGTH randomized clinical trial. JAMA. 2020e2022258.

104551. Suradom C, Suttajit S, Oon-Arom A, Maneeton B, Srisurapanont M. Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation for prevention and treatment of perinatal depression: a systematic review and meta-analysis of randomized-controlled trials. Nord PubMed

66498. Kuenzel U and Bertsch S. Clinical experiences with a standardized commercial fish oil product containing 33.5% omega-3 fatty acids - field trial with 3958 hyperlipemic patients in general practitioner practice. In: Chandra RK. Health Effects of Fish and F
Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›
Diarrhea reported in 4.6% of FDA reports for Ivermectin Additional detail

Fish Oil

Recorded for Fish Oil in the same Natural Medicines adverse-effect record shown under Bleeding or bruising above.

Ivermectin

Listed in the ADVERSE REACTIONS section of the FDA label for Ivermectin, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Showing the 10 most notable of 13 shared effects — ranked by how unusual each one is, not just whether both lists mention it.

Reported for Fish Oil but not commonly for Ivermectin: stomach upset, a heart attack, an irregular heartbeat and a change in taste.

Effects for Ivermectin come from the ADVERSE REACTIONS section of its FDA label; effects for Fish Oil come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 6,298 voluntary FDA FAERS reports for Ivermectin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Fish Oil in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally and appropriately. Intake of fish oil during pregnancy does not appear to adversely affect the fetus or nursing infant. One large clinical trial shows that intake of fish oil from the 24th week of gestation increases the odds of the child having overweight and having metabolic syndrome measurements at age 10 when compared with placebo. More research is needed to confirm these findings. The adequate intake level of omega-3 fatty acids during pregnancy is 1.4 grams daily; the adequate intake level during lactation is 1.3 grams daily. If possible, people who are trying to become pregnant, as well as those who are pregnant or lactating, should avoid swordfish, king mackerel, and tilefish (also called golden bass or golden snapper), as these may contain high levels of methylmercury. Pregnant individuals should also limit consumption of other fatty fish to 12 ounces, or about 3-4 servings, per week.

Pregnancy And Lactation Possibly Unsafe

When fish oil from dietary sources are consumed in large amounts. Fatty fish can contain significant amounts of toxins such as mercury, polychlorinated biphenyls (PCBs), dioxin, and dioxin-related compounds. If possible, people who are trying to become pregnant, as well as those who are pregnant or lactating, should avoid swordfish, king mackerel, and tilefish (also called golden bass or golden snapper), as these may contain high levels of methylmercury. Pregnant individuals should also limit consumption of other fatty fish to 12 ounces, or about 3-4 servings, per week.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Ivermectin Products Have a Food Rule — Fish Oil Should Not Break It

At least one FDA label for a product containing Ivermectin says to take it on an empty stomach. Most supplements — Fish Oil included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Ivermectin on its own and move Fish Oil to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ivermectin products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Patients should take tablets on an empty stomach with water.

From the Dosage and Administration section of the FDA label we read for Ivermectin — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Fish Oil or Ivermectin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Fish Oil or Ivermectin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Ivermectin

This page covers Fish Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ivermectin page lists 58 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), St. John's Wort (major), Sweet Orange (major), Bitter Melon (moderate) and Black Pepper (moderate).

By severity: 3 major · 37 moderate · 18 minor.

Open the Ivermectin interaction page

One more smart check

Taking Fish Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 4,777 real supplement products containing Fish Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Fish Oil. Even though Fish Oil itself has no known interaction with Ivermectin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Fish Oil and Ivermectin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Fish Oil

Top 5%

#58 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Ivermectin

Top 1%

#12 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Fish Oil reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Fish Oil and Ivermectin records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Fish Oil

What is Fish Oil?

High triglycerides
Heart health
Joint pain and inflammation
Brain and eye health
Dry eyes

Fish oil provides omega-3 fatty acids (EPA and DHA) that are best known for lowering high triglyceride levels. The evidence for other heart and health benefits is mixed, and it is generally well tolerated. Talk with your pharmacist or doctor before starting it, especially if you take blood thinners or have a fish allergy.

Oil from fatty fish (such as mackerel, salmon, sardines, and anchovies) · Softgel capsules, liquid, gummies, and fortified foods

An interaction check asks whether these two react with each other — it does not ask whether Fish Oil is a good idea for someone in your situation. Here is what our Fish Oil record says about it on its own.

Fish Oil: dosing

There is no single standard dose of fish oil for everyone, and the right amount depends on why it is being used and the EPA/DHA content of the product. Higher, prescription-strength doses used for very high triglycerides should only be used under a doctor's supervision.

From our Fish Oil monograph — the full record covers uses, side effects and every documented interaction.

Read the full Fish Oil monograph & all interactions

Medication

About Ivermectin

What Is Ivermectin Used For?

Brand names: Stromectol, Mectizan, Sklice, Soolantra

Ivermectin tablets (including Stromectol) are used to treat two parasitic infections: strongyloidiasis (a roundworm infection of the intestinal tract) and onchocerciasis (river blindness, caused by a parasitic worm spread by blackfly bites). These are prescription uses for serious infections.

Topical ivermectin lotion — sold under several names including RID One and Done, Head Lice Treatment Ivermectin Lotion, Scalp Care Lotions, and others — is applied to the scalp to treat head lice. A separate topical ivermectin cream (1%), available as Soolantra and ivermectin cream 1%, is used to treat the inflammatory pimple-like bumps of rosacea.

Most-Reported Side Effects for Ivermectin

From FAERS, the FDA’s public side-effect reporting system (6,298 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Headache 647 reports

Asthenia 590 reports

Fever 485 reports

Pruritus 388 reports

Diarrhea 292 reports

See full Ivermectin drug information

Keep checking

Other Drugs & Fish Oil

Browse every other medication we’ve checked against Fish Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

207Moderate

120Minor

2,502No known interaction

207 Moderate 120 Minor 2,502 No interaction

Moderate

207 interactions

Showing 60 of 207 moderate interactions — see all 207 on the Fish Oil page.

Minor

120 interactions

Showing 60 of 120 minor interactions — see all 120 on the Fish Oil page.

No interaction 2,502 drugs checked — show the list

We also checked Fish Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,502 medications checked with no known interaction — see the full Fish Oil list.

See the full Fish Oil interactions page

See every supplement checked against Ivermectin, ranked by severity

Evidence & sources

Fish Oil References

The 157 references that drive our Fish Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
Allard JP, Kurian R, Aghdassi E, Muggli R, et al. Lipid peroxidation during n-3 fatty acid and vitamin E supplementation in humans. Lipids 1997;32:535-41.. PubMed
Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
Onwude JL, Lilford RJ, Hjartardottir H, et al. A randomised double blind placebo controlled trial of fish oil in high risk pregnancy. Br J Obstet Gynaecol 1995;102:95-100. PubMed
Bulstra-Ramakers MT, Huisjes HJ, Visser GH. The effects of 3g eicosapentaenoic acid daily on recurrence of intrauterine growth retardation and pregnancy induced hypertension. Br J Obstet Gynaecol 1995;102:123-6. PubMed
Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
Hawthorne AB, Daneshmend TK, Hawkey CJ, et al. Treatment of ulcerative colitis with fish oil supplementation: a prospective 12 month randomised controlled trial. Gut 1992;33:922-8. PubMed
D'Almeida A, Carter JP, Anatol A, Prost C. Effects of a combination of evening primrose oil (gamma linolenic acid) and fish oil (eicosapentaenoic + docahexaenoic acid) versus magnesium, and versus placebo in preventing pre-eclampsia. Women Health 1992;19 PubMed
FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
Montori VM, Farmer A, Wollan PC, Dinneen SF. Fish oil supplementation in type 2 diabetes: a quantitative systemic review (abstract). Diabetes Care 2000;23:1407-15.
Anon. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Soprawivenza nell'Infarto miocardico. Lancet 1999;354:447-55. DOI
Adler A, Holub BJ. Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men. Am J Clin Nutr 1997;65:445-50. PubMed
Higdon JV, Liu J, Du S, et al. Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as asses
Kastrup EK. Drug Facts and Comparisons. 1998 ed. St. Louis, MO: Facts and Comparisons, 1998.
Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. N Engl J Med 1996;334:1557-60. PubMed
Belluzzi A, Brignola C, Campieri M, et al. Effects of new fish oil derivative on fatty acid phospholipid-membrane pattern in a group of Crohn's disease patients. Dig Dis Sci 1994;39:2589-94. PubMed
Mahan LK, Escott-Stump S. Krause's Food, Nutrition, and Diet Therapy. 9th edition. W.B. Saunders Co., Philadelphia, PA, 1996.
Yetiv JZ. Clinical applications of fish oils. JAMA 1988;260:665-70. DOI
de Deckere EAM, Korver O, Verschuren PM, Katan MB. Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. Eur J Clin Nutr 1998;52:749-53. PubMed
Sorensen NS, Marckmann P, Hoy CE, et al. Effect of fish-oil-enriched margarine on plasma lipids, low-density-lipoprotein particle composition, size, and susceptibility to oxidation. Am J Clin Nutr 1998;68:235-41. PubMed
Kelley DS, Rudolph IL. Effect of individual fatty acids of omega-6 and omega-3 type on human immune status and role of eicosanoids. Nutrition 2000;16:143-5.
Meydani SN, Dinarello CA. Influence of dietary fatty acids on cytokine production and its clinical implications. Nutr Clin Pract 1993;8:65-72. PubMed
Caicoya M. Fish consumption and stroke: a community case-control study in Asturias, Spain. Neuroepidemiology 2002;21:107-14. PubMed
Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
Dewailly E, Blanchet C, Lemieux S, et al. n-3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik. Am J Clin Nutr 2001;74:464-73. PubMed
Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
Maresta A, Balduccelli M, Varani E, et al. Prevention of postcoronary angioplasty restenosis by omega-3 fatty acids: main results of the Esapent for Prevention of Restenosis Italian Study (ESPRIT). Am Heart J 143:E5. PubMed
Deutch B, Jorgensen EB, Hansen JC. n-3 PUFA from fish or seal oil reduce atherogenic risk indicators in Danish women. Nutr Res 2000;20:1065-77. DOI
Higgins S, McCarthy SN, Corridan BM, et al. Measurement of free cholesterol, cholesteryl esters and cholesteryl linoleate hydroperoxide in copper-oxidised low density lipoprotein in healthy volunteers supplemented with a low dose of n-3 polyunsaturated f
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Pharmacist Counseling Corner

Taking Fish Oil and Ivermectin Together: Common Questions

Is it safe to take Fish Oil with Ivermectin?

We do not list a known interaction between Fish Oil and Ivermectin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Fish Oil and Ivermectin have any of the same side effects?

Yes — our sources link each of them separately to 10 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

Should I take Fish Oil and Ivermectin at the same time of day?

At least one FDA label for a product containing Ivermectin says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Ivermectin on its own and move Fish Oil to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.

How was the Fish Oil and Ivermectin combination checked?

Interactions in our licensed database are recorded against drug classes. Ivermectin is filed under 4 classifications, and Fish Oil has documented interactions with 9 drug classes — none of Ivermectin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Fish Oil interact with any other medications?

Yes. Fish Oil has 327 documented drug interactions in our database — Ivermectin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Ivermectin interact with any supplements?

Yes. Ivermectin has documented interactions with 58 supplements in our database — Fish Oil is not one of them. The Ivermectin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.