Drug & supplement interaction

Forsythia + Epinephrine Hydrochloride

Epinephrine Hydrochloride brand name: Adrenalin.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Forsythia and Epinephrine Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Forsythia and Epinephrine Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Epinephrine Hydrochloride and Forsythia in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Forsythia safety at a glance

Forsythia overall Use caution Generally used short-term in traditional medicine, but human safety data are limited.
Pregnancy Avoid Not enough safety data; avoid during pregnancy.
Breastfeeding Avoid Not enough safety data; best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Epinephrine Hydrochloride and Forsythia? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Epinephrine Hydrochloride

Interactions in our licensed database are recorded against drug classes, not just single drug names. Epinephrine Hydrochloride is filed under a single classification — alpha-adrenergic agonists. Forsythia has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and azithromycin (zithromax) (minor) — and none of Epinephrine Hydrochloride’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Forsythia Does Interact With Other Medications

Forsythia has 122 moderate, 1 minor known drug interactions in our database — Epinephrine Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Forsythia

Covers the 2,830 medications we’ve checked against Forsythia. Pick one to open its full report.

What to actually watch for

What Epinephrine Hydrochloride’s Own FDA Label Lists

This is not an interaction — none of it involves Forsythia. These are the most notable effects listed in the ADVERSE REACTIONS section of Epinephrine Hydrochloride’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on
  • Chest pain Worth acting on
  • Raised blood pressure Worth acting on
  • A severe allergic reaction Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on
  • Tremor or shakiness
  • Sweating
  • A fast or pounding heartbeat
  • Anxiety or restlessness

Showing the 10 most notable of 14 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Epinephrine Hydrochloride. Read the label on DailyMed › Forsythia’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Forsythia side to compare — that is a limit of the record, not a statement that Forsythia has no side effects.

Everything else you take

See Every Supplement That Interacts With Epinephrine Hydrochloride

This page covers Forsythia only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Epinephrine Hydrochloride page lists 1 supplement it has a documented interaction with, worst first, each one explained.

The most serious there right now: Butcher's Broom (moderate).

By severity: 1 moderate.

From our pharmacist’s overview on the Epinephrine Hydrochloride page

“Anyone who carries epinephrine hydrochloride (Adrenalin) for severe allergic reactions, or receives it in emergency care, can look at this page without worry. A single supplement is on file, butcher's broom, rated moderate, and the issue is overlap.”

Reviewed by 2 · Jul 18, 2026

Open the Epinephrine Hydrochloride interaction page

One more smart check

Taking Forsythia as Part of a Dietary Supplement Product? Check It for Interactions

We hold 355 real supplement products containing Forsythia, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Forsythia. Even though Forsythia itself has no known interaction with Epinephrine Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Forsythia and Epinephrine Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Forsythia
Top 25%

#336 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Epinephrine Hydrochloride
Steady interest

#2,673 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Forsythia reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Forsythia and Epinephrine Hydrochloride records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Forsythia

What is Forsythia?

  • Colds and flu symptoms
  • Sore throat
  • Fever
  • Inflammation
  • Antimicrobial support

Forsythia is a traditional Chinese herb, used mainly for cold and flu symptoms and as part of multi-herb formulas. Most evidence comes from laboratory, animal, and traditional use rather than strong human studies, so its real-world benefits remain unproven. Talk to your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or taking other medicines.

Forsythia suspensa · Oleaceae · Dried fruit (and sometimes leaves) · Dried fruit, teas, decoctions, capsules, and herbal formulas

An interaction check asks whether these two react with each other — it does not ask whether Forsythia is a good idea for someone in your situation. Here is what our Forsythia record says about it on its own.

Forsythia: dosing

There is no well-established standardized dose for forsythia. Traditional preparations use the dried fruit in decoctions, often as part of a multi-herb formula, and amounts vary by product and practitioner.If you use a commercial supplement, follow the directions on the product label and do not exceed the recommended amount.

From our Forsythia monograph — the full record covers uses, side effects and every documented interaction.

Read the full Forsythia monograph & all interactions
Medication

About Epinephrine Injection

What Is Epinephrine Injection Used For?

Brand name: Adrenalin

Epinephrine Injection (0.3 mg and 0.15 mg strengths) is used for emergency treatment of allergic reactions (Type I), including anaphylaxis. Triggers include stinging insects (bees, wasps, hornets, yellow jackets, fire ants), biting insects (such as mosquitoes), foods, drugs, allergen immunotherapy, diagnostic substances like radiocontrast media, and other allergens. It is also used for idiopathic anaphylaxis (no known cause) and exercise-induced anaphylaxis.

It is meant for immediate use in people at increased risk for anaphylaxis, including those with a history of it. It is emergency supportive therapy only. It does not replace immediate medical care.

See full Epinephrine Injection drug information
Keep checking

Other Drugs & Forsythia

Browse every other medication we’ve checked against Forsythia — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
122Moderate
1Minor
2,706No known interaction
Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Forsythia page.

Minor

1 interaction

No interaction 2,706 drugs checked — show the list
Evidence & sources

Forsythia References

The 3 references that drive our Forsythia monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kong XT, Fang HT, Jiang GQ, et al. Treatment of acute bronchiolitis with Chinese herbs. Arch Dis Child 1993;68:468-71. PubMed
  2. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  3. Li XG, Ni J, Shen S, Wang XP, Tian JC. Pharmacokinetic interaction of Forsythia suspensa extract and azithromycin injection after single and co-intravenous administration in rats. Chin J Nat Med 2020;18(3):234-240. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Forsythia and Epinephrine Hydrochloride Together: Common Questions

Is it safe to take Forsythia with Epinephrine Hydrochloride?
We do not list a known interaction between Forsythia and Epinephrine Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Forsythia and Epinephrine Hydrochloride combination checked?
Interactions in our licensed database are recorded against drug classes. Epinephrine Hydrochloride is filed under 1 classification, and Forsythia has documented interactions with 2 drug classes — none of Epinephrine Hydrochloride's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Forsythia interact with any other medications?
Yes. Forsythia has 123 documented drug interactions in our database — Epinephrine Hydrochloride is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Epinephrine Hydrochloride interact with any supplements?
Yes. Epinephrine Hydrochloride has documented interactions with 1 supplement in our database — Forsythia is not one of them. The Epinephrine Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Epinephrine Hydrochloride and Forsythia?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.