Drug & supplement interaction

Hyperimmune Egg + Tolazamide

Tolazamide brand name: Tolinase.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Hyperimmune Egg and Tolazamide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Hyperimmune Egg and Tolazamide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Tolazamide and Hyperimmune Egg in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Hyperimmune Egg at all — not against Tolazamide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Hyperimmune Egg safety at a glance

Hyperimmune Egg overall Use caution Generally considered low-risk for most people, but it is essentially an egg product and can trigger allergies.
Pregnancy Use caution Not well studied in pregnancy; talk to your doctor before using.
Breastfeeding Use caution Not well studied while breastfeeding; check with your doctor first.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Tolazamide and Hyperimmune Egg? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Hyperimmune Egg Itself Has Been Linked To

This is not an interaction — nothing below involves Tolazamide. It is the side-effect record for Hyperimmune Egg on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Hyperimmune Egg, this list is the first place to look.

  • Bloating or gas / Diarrhea Additional detail

    “Orally, hyperimmune egg products have been reported to cause diarrhea, gas, stomach ache, and bloating.”

    Hyperimmune Egg · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 13213. Karge WH, Deluca JP, Marchitelli LJ, et al. Pilot study on the effect of hyperimmune egg protein on elevated cholesterol levels and cardiovascular risk factors. J Med Food 1999;2:51-63. PubMed
    2. 102904. Scheett TM, Martin TD, Carr BM, Webster MJ. A Comparison of Hyperimmune Egg Protein and Placebo for Efficacy and Safety Among Healthy Young Adults (poster). J Int Soc Sport Nutr 2009;6(S1):P8. DOI

Everything above comes from the Natural Medicines adverse-effect record for Hyperimmune Egg — expand a row for the licensed statement it rests on. We haven’t matched Tolazamide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Tolazamide.

Everything else you take

See Every Supplement That Interacts With Tolazamide

This page covers Hyperimmune Egg only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Tolazamide page lists 272 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate) and Agaricus Mushroom (moderate).

By severity: 2 major · 230 moderate · 40 minor.

From our pharmacist’s overview on the Tolazamide page

“Tolazamide (Tolinase) lowers blood sugar in type 2 diabetes, and I would handle its supplement list with care, because nearly everything listed can drag blood sugar lower still. Herbs and foods with glucose-lowering effects dominate the file, and stacked on a pill that already lowers glucose they raise the odds of hypoglycemia, blood s…”

Reviewed by 2 · Jul 18, 2026

Open the Tolazamide interaction page

How much people look this up

Where Hyperimmune Egg and Tolazamide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Hyperimmune Egg
Steady interest

#775 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Tolazamide
Top half

#1,381 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hyperimmune Egg reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Hyperimmune Egg and Tolazamide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Hyperimmune Egg

What is Hyperimmune Egg?

  • Immune support
  • Digestive health
  • Diarrhea prevention
  • Joint comfort
  • General wellness

Hyperimmune egg is a dried egg product from hens vaccinated against common germs, so the eggs contain extra antibodies (mainly IgY). Some small studies suggest possible benefits for gut health and immune support, but the overall evidence is limited and not strong. People with egg allergy should avoid it, and pregnant or breastfeeding women should check with a doctor first.

Whole eggs (and egg powder) from hens immunized against specific microbes · Powder, capsules, tablets, protein shakes/drink mixes

An interaction check asks whether these two react with each other — it does not ask whether Hyperimmune Egg is a good idea for someone in your situation. Here is what our Hyperimmune Egg record says about it on its own.

Hyperimmune Egg: dosing

There is no official or standardized dose for hyperimmune egg. Products vary widely in strength and form, from powders to capsules.The best advice is to follow the directions on the product label and not exceed the recommended amount.

From our Hyperimmune Egg monograph — the full record covers uses, side effects and every documented interaction.

Read the full Hyperimmune Egg monograph & all interactions
Medication

About Tolazamide

What Is Tolazamide Used For?

Brand name: Tolinase

  • Tolazamide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Tolazamide is in a class of medications called sulfonylureas. Tolazamide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Tolazamide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

  • Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

See full Tolazamide drug information
Keep checking

Other Drugs & Hyperimmune Egg

Browse every other medication we’ve checked against Hyperimmune Egg — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Hyperimmune Egg References

The 10 references that drive our Hyperimmune Egg monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sarker SA, Casswall TH, Juneja LR, et al. Randomized, placebo-controlled, clinical trial of hyperimmunized chicken egg yolk immunoglobulin in children with rotavirus diarrhea. J Pediatr Gastroenterol Nutr 2001;32:19-25. DOI
  2. Greenblatt HC, Adalsteinsson O, Kagen L. Administration to arthritis patients of a dietary supplement containing immune egg: An open-label pilot study. J Med Food 1998;1:171-9. DOI
  3. Karge WH, Deluca JP, Marchitelli LJ, et al. Pilot study on the effect of hyperimmune egg protein on elevated cholesterol levels and cardiovascular risk factors. J Med Food 1999;2:51-63. PubMed
  4. Nguyen SV, Nguyen MTH, Tran BC, Ho MTQ, Umeda K, Rahman S. Evaluation of lozenges containing egg yolk antibody against Porphyromonas gingivalis gingipains as an adjunct to conventional non-surgical therapy in periodontitis patients: A randomized controlle
  5. Scheett TM, Martin TD, Carr BM, Webster MJ. A Comparison of Hyperimmune Egg Protein and Placebo for Efficacy and Safety Among Healthy Young Adults (poster). J Int Soc Sport Nutr 2009;6(S1):P8. DOI
  6. Scheett TM, Martin TD, Carr BM, et al. Hyperimmune Egg Protein Decreases Submaximal Heart Rate and Increases Peak Power (poster). Medicine & Science in Sports Medicine & Exercise 2007;39(5):S365. https://insights.ovid.com/medicine-science-sports-exercise/ DOI
  7. Kollberg H, Carlander D, Olesen H, Wejaker PE, Johannesson M, Larsson A. Oral administration of specific yolk antibodies (IgY) may prevent Pseudomonas aeruginosa infections in patients with cystic fibrosis: a phase 1 feasibility study. Pediatr Pulmonol 20
  8. Nilsson E, Larsson A, Olesen HV, Wejaker PE, Kollberg H. Good effect of IgY against Pseudomonas aeruginosa infections in cystic fibrosis patients. Pediatr Pulmonol 2008;43(9):892-9.
  9. Suzuki H, Nomura S, Masaoka T, et al. Effect of dietary anti-Helicobacter pylori-urease immunoglobulin Y on Helicobacter pylori infection. Aliment Pharmacol Ther 2004;20 suppl 1:185-92. PubMed
  10. Horie K, Horie N, Abdou AM, et al. Suppressive effect of functional drinking yogurt containing specific egg yolk immunoglobulin on Helicobacter pylori in humans. J Dairy Sci 2004;87(12):4073-9. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Hyperimmune Egg and Tolazamide Together: Common Questions

Is it safe to take Hyperimmune Egg with Tolazamide?
We do not list a known interaction between Hyperimmune Egg and Tolazamide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Tolazamide interact with any supplements?
Yes. Tolazamide has documented interactions with 272 supplements in our database — Hyperimmune Egg is not one of them. The Tolazamide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Tolazamide and Hyperimmune Egg?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.