Drug & supplement interaction

Hyperimmune Egg + Lisinopril

Lisinopril brand names: Zestril, Prinivil, Qbrelis.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Hyperimmune Egg and Lisinopril in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Hyperimmune Egg and Lisinopril

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lisinopril and Hyperimmune Egg in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Hyperimmune Egg at all — not against Lisinopril, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Hyperimmune Egg safety at a glance

Hyperimmune Egg overall Use caution Generally considered low-risk for most people, but it is essentially an egg product and can trigger allergies.
Pregnancy Use caution Not well studied in pregnancy; talk to your doctor before using.
Breastfeeding Use caution Not well studied while breastfeeding; check with your doctor first.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lisinopril and Hyperimmune Egg? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Hyperimmune Egg and Lisinopril May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Bloating or gas / Diarrhea reported in 5.7% of FDA reports for Lisinopril Additional detail

    Hyperimmune Egg

    “Orally, hyperimmune egg products have been reported to cause diarrhea, gas, stomach ache, and bloating.”

    Hyperimmune Egg · Natural Medicines adverse-effect record, reported in diarrhea.

    2 sources cited
    1. 13213. Karge WH, Deluca JP, Marchitelli LJ, et al. Pilot study on the effect of hyperimmune egg protein on elevated cholesterol levels and cardiovascular risk factors. J Med Food 1999;2:51-63. PubMed
    2. 102904. Scheett TM, Martin TD, Carr BM, Webster MJ. A Comparison of Hyperimmune Egg Protein and Placebo for Efficacy and Safety Among Healthy Young Adults (poster). J Int Soc Sport Nutr 2009;6(S1):P8. DOI

    Lisinopril

    Listed in the ADVERSE REACTIONS section of the FDA label for Lisinopril, and in voluntary FDA adverse-event reports. Read the label on DailyMed ›

Effects for Lisinopril come from the ADVERSE REACTIONS section of its FDA label; effects for Hyperimmune Egg come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 313,746 voluntary FDA FAERS reports for Lisinopril that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Hyperimmune Egg or Lisinopril

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Hyperimmune Egg or Lisinopril, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Lisinopril

This page covers Hyperimmune Egg only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lisinopril page lists 167 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Siberian Cocklebur (major).

By severity: 6 major · 137 moderate · 24 minor.

From our pharmacist’s overview on the Lisinopril page

“Lisinopril is an ACE inhibitor that lowers blood pressure and protects the heart and kidneys, so the 167 supplements and herbs on this page warrant genuine care. Six carry a major rating, and those deserve your attention first.”

Reviewed by 2 · Jul 18, 2026

Open the Lisinopril interaction page

How much people look this up

Where Hyperimmune Egg and Lisinopril Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Hyperimmune Egg
Steady interest

#909 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lisinopril
Top 1%

#25 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hyperimmune Egg reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Hyperimmune Egg and Lisinopril records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Hyperimmune Egg

What is Hyperimmune Egg?

  • Immune support
  • Digestive health
  • Diarrhea prevention
  • Joint comfort
  • General wellness

Hyperimmune egg is a dried egg product from hens vaccinated against common germs, so the eggs contain extra antibodies (mainly IgY). Some small studies suggest possible benefits for gut health and immune support, but the overall evidence is limited and not strong. People with egg allergy should avoid it, and pregnant or breastfeeding women should check with a doctor first.

Whole eggs (and egg powder) from hens immunized against specific microbes · Powder, capsules, tablets, protein shakes/drink mixes

An interaction check asks whether these two react with each other — it does not ask whether Hyperimmune Egg is a good idea for someone in your situation. Here is what our Hyperimmune Egg record says about it on its own.

Hyperimmune Egg: dosing

There is no official or standardized dose for hyperimmune egg. Products vary widely in strength and form, from powders to capsules.The best advice is to follow the directions on the product label and not exceed the recommended amount.

From our Hyperimmune Egg monograph — the full record covers uses, side effects and every documented interaction.

Read the full Hyperimmune Egg monograph & all interactions
Medication

About Lisinopril

What Is Lisinopril Used For?

Brand names: Zestril, Prinivil, Qbrelis

Lisinopril treats high blood pressure (hypertension) in adults and children 6 years and older, and can be used alone or alongside other blood pressure medicines. Lowering blood pressure reduces the risk of strokes and heart attacks. The tablet combination product containing lisinopril and hydrochlorothiazide is specifically indicated for high blood pressure.

Lisinopril is also used as an add-on therapy to reduce signs and symptoms of systolic heart failure, and to reduce the risk of death in people who are hemodynamically stable (have reasonably stable circulation) within 24 hours of an acute heart attack (acute myocardial infarction).

Most-Reported Side Effects for Lisinopril

From FAERS, the FDA’s public side-effect reporting system (313,746 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 20,515 reports
Nausea 19,130 reports
Diarrhea 17,858 reports
Dyspnea 14,363 reports
Dizziness 13,969 reports
See full Lisinopril drug information
Keep checking

Other Drugs & Hyperimmune Egg

Browse every other medication we’ve checked against Hyperimmune Egg — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Hyperimmune Egg against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Hyperimmune Egg list.

See the full Hyperimmune Egg interactions page
See every supplement checked against Lisinopril, ranked by severity
Evidence & sources

Hyperimmune Egg References

The 10 references that drive our Hyperimmune Egg monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sarker SA, Casswall TH, Juneja LR, et al. Randomized, placebo-controlled, clinical trial of hyperimmunized chicken egg yolk immunoglobulin in children with rotavirus diarrhea. J Pediatr Gastroenterol Nutr 2001;32:19-25. DOI
  2. Greenblatt HC, Adalsteinsson O, Kagen L. Administration to arthritis patients of a dietary supplement containing immune egg: An open-label pilot study. J Med Food 1998;1:171-9. DOI
  3. Karge WH, Deluca JP, Marchitelli LJ, et al. Pilot study on the effect of hyperimmune egg protein on elevated cholesterol levels and cardiovascular risk factors. J Med Food 1999;2:51-63. PubMed
  4. Nguyen SV, Nguyen MTH, Tran BC, Ho MTQ, Umeda K, Rahman S. Evaluation of lozenges containing egg yolk antibody against Porphyromonas gingivalis gingipains as an adjunct to conventional non-surgical therapy in periodontitis patients: A randomized controlle
  5. Scheett TM, Martin TD, Carr BM, Webster MJ. A Comparison of Hyperimmune Egg Protein and Placebo for Efficacy and Safety Among Healthy Young Adults (poster). J Int Soc Sport Nutr 2009;6(S1):P8. DOI
  6. Scheett TM, Martin TD, Carr BM, et al. Hyperimmune Egg Protein Decreases Submaximal Heart Rate and Increases Peak Power (poster). Medicine & Science in Sports Medicine & Exercise 2007;39(5):S365. https://insights.ovid.com/medicine-science-sports-exercise/ DOI
  7. Kollberg H, Carlander D, Olesen H, Wejaker PE, Johannesson M, Larsson A. Oral administration of specific yolk antibodies (IgY) may prevent Pseudomonas aeruginosa infections in patients with cystic fibrosis: a phase 1 feasibility study. Pediatr Pulmonol 20
  8. Nilsson E, Larsson A, Olesen HV, Wejaker PE, Kollberg H. Good effect of IgY against Pseudomonas aeruginosa infections in cystic fibrosis patients. Pediatr Pulmonol 2008;43(9):892-9.
  9. Suzuki H, Nomura S, Masaoka T, et al. Effect of dietary anti-Helicobacter pylori-urease immunoglobulin Y on Helicobacter pylori infection. Aliment Pharmacol Ther 2004;20 suppl 1:185-92. PubMed
  10. Horie K, Horie N, Abdou AM, et al. Suppressive effect of functional drinking yogurt containing specific egg yolk immunoglobulin on Helicobacter pylori in humans. J Dairy Sci 2004;87(12):4073-9. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Hyperimmune Egg and Lisinopril Together: Common Questions

Is it safe to take Hyperimmune Egg with Lisinopril?
We do not list a known interaction between Hyperimmune Egg and Lisinopril. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Hyperimmune Egg and Lisinopril have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Lisinopril interact with any supplements?
Yes. Lisinopril has documented interactions with 167 supplements in our database — Hyperimmune Egg is not one of them. The Lisinopril interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Hyperimmune Egg monograph Uses, safety profile, and every drug interaction in one place Lisinopril drug information The full plain-English guide to this medication Lisinopril supplement interactions Every supplement checked against Lisinopril, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 10 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lisinopril and Hyperimmune Egg?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.