Drug & supplement interaction

Kinetin + Carvedilol

Carvedilol brand names: Coreg, Coreg CR.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Kinetin and Carvedilol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Carvedilol states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Kinetin and Carvedilol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Carvedilol and Kinetin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Kinetin safety at a glance

Kinetin overall Use caution Generally used topically in cosmetics; oral supplement use is not well studied and not recommended.
Pregnancy Avoid There is not enough safety information, so it is best to avoid during pregnancy unless your doctor approves.
Breastfeeding Avoid Safety during breastfeeding has not been established, so caution or avoidance is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Carvedilol and Kinetin? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Carvedilol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Carvedilol is filed under 7 classifications — including beta-blockers, cytochrome p450 2c9 (cyp2c9) substrates, antihypertensive drugs. Kinetin has documented interactions with 1 drug class — the most serious being anticoagulant/antiplatelet drugs (moderate) — and none of Carvedilol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Kinetin Does Interact With Other Medications

Kinetin has 122 moderate known drug interactions in our database — Carvedilol isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Kinetin

Covers the 2,830 medications we’ve checked against Kinetin. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Kinetin and Carvedilol May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Ringing in the ears Additional detail

    Kinetin

    “Orally, the most common adverse effect reported from kinetin is nausea. Headache, diarrhea, tinnitus, flushing, and rash are less common. Topically, kinetin seems to be well tolerated. Erythema, dryness, peeling, burning, stinging, and itching have been reported. However, it is unknown if these symptoms are related to kinetin or other ingredients in the products used.”

    Kinetin · Natural Medicines adverse-effect record, reported in cluster headache.

    3 sources cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed
    2. 100044. Wanitphakdeedecha R, Meeprathom W, Manuskiatti W. Efficacy and safety of 0.1% kinetin cream in the treatment of photoaging skin. Indian J Dermatol Venereol Leprol. 2015;81(5):547. PubMed
    3. 100050. Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL. Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea. Clin Exp Dermatol. 2007;32(6):693-5. PubMed

    “Orally, kinetin has been reported to cause tinnitus rarely. Limited research suggests that this reaction is not dose-dependent.”

    Kinetin · Natural Medicines adverse-effect record, reported in tinnitus.

    1 source cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed

    Carvedilol

    Listed in the ADVERSE REACTIONS section of the FDA label for Carvedilol. Read the label on DailyMed ›

  • Itching / A skin rash Additional detail

    Kinetin

    “Orally, kinetin has been reported to cause flushing and rash rarely. Limited research suggests that these reactions are not dose-dependent. Topically, kinetin has been reported to cause erythema, dryness, peeling, burning, stinging, and itching. However, it is unknown if these symptoms are related to kinetin or other ingredients in the products used.”

    Kinetin · Natural Medicines adverse-effect record, reported in erythema.

    2 sources cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed
    2. 100044. Wanitphakdeedecha R, Meeprathom W, Manuskiatti W. Efficacy and safety of 0.1% kinetin cream in the treatment of photoaging skin. Indian J Dermatol Venereol Leprol. 2015;81(5):547. PubMed

    Carvedilol

    Listed in the ADVERSE REACTIONS section of the FDA label for Carvedilol. Read the label on DailyMed ›

  • Diarrhea / Nausea Additional detail

    Kinetin

    “Orally, the most common adverse effect reported from kinetin is nausea. Lower doses generally cause mild nausea; however, doses of 16.8 mg/kg to 23.5 mg/kg daily increase the chance of severe nausea. Kinetin has also been reported to cause diarrhea, although at a lower rate.”

    Kinetin · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed

    Carvedilol

    Listed in the ADVERSE REACTIONS section of the FDA label for Carvedilol. Read the label on DailyMed ›

  • Headache Additional detail

    Kinetin

    “Orally, kinetin has been reported to cause headache rarely. Limited research suggests that this reaction is not dose-dependent.”

    Kinetin · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 100046. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed

    Carvedilol

    Listed in the ADVERSE REACTIONS section of the FDA label for Carvedilol. Read the label on DailyMed ›

Reported for Kinetin but not commonly for Carvedilol: flushing.

Effects for Carvedilol come from the ADVERSE REACTIONS section of its FDA label; effects for Kinetin come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

How to take them

Some Carvedilol Products Have a Food Rule — Kinetin Should Not Break It

At least one FDA label for a product containing Carvedilol says to take it with food. If you take Kinetin on an empty stomach out of habit, keep them separate — and take Carvedilol with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Carvedilol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

2 DOSAGE AND ADMINISTRATION COREG should be taken with food to slow the rate of absorption and reduce the incidence of orthostatic effects.

From the Dosage and Administration section of the FDA label we read for Carvedilol — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Kinetin or Carvedilol

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Kinetin or Carvedilol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Carvedilol

This page covers Kinetin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Carvedilol page lists 211 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Grapefruit (major) and Indian Snakeroot (major).

By severity: 6 major · 171 moderate · 34 minor.

From our pharmacist’s overview on the Carvedilol page

“People take carvedilol (Coreg) for heart failure and high blood pressure, conditions where a sudden swing in pressure or heart rate matters, and its supplement list runs to 211 ingredients, so this one calls for genuine care. More than half of those entries lower blood pressure on their own, fish oil and celery seed among them, and can…”

Reviewed by 2 · Jul 18, 2026

Open the Carvedilol interaction page

How much people look this up

Where Kinetin and Carvedilol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Kinetin
Steady interest

#865 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Carvedilol
Top 10%

#275 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Kinetin reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Kinetin and Carvedilol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Kinetin

What is Kinetin?

  • Anti-aging skincare
  • Skin smoothing and texture
  • Reducing skin dryness and roughness
  • Evening skin tone
  • Cosmetic moisturizing

Kinetin is a plant growth hormone (a cytokinin) used mainly in topical anti-aging and skincare products, not as an oral dietary supplement. Early laboratory research and small studies suggest it may help skin texture and hydration, but high-quality human evidence is limited. If you want to try it, use it as a cosmetic skin product and check with a pharmacist or dermatologist, especially if you have sensitive skin.

Plant-derived cytokinin (a type of plant hormone); used as a purified compound · Topical creams, serums, lotions, and cosmetic skincare products

An interaction check asks whether these two react with each other — it does not ask whether Kinetin is a good idea for someone in your situation. Here is what our Kinetin record says about it on its own.

Kinetin: dosing

There is no established standard dose for kinetin, and it is not meant to be taken as an oral supplement. In cosmetic skincare, it appears as one ingredient among many, usually in low concentrations.The best approach is to follow the directions on the product label for how often to apply it. Do not assume that using more product more often will give better results.

From our Kinetin monograph — the full record covers uses, side effects and every documented interaction.

Read the full Kinetin monograph & all interactions
Medication

About Carvedilol

What Is Carvedilol Used For?

Brand names: Coreg, Coreg CR

Carvedilol is used to treat three main conditions: mild-to-severe chronic heart failure, high blood pressure (hypertension), and reduced heart pumping function (left ventricular dysfunction) in people who have survived a heart attack. For heart failure, it is usually prescribed alongside other medications such as diuretics, ACE inhibitors, and digitalis to help people live longer and reduce the chance of hospital stays.

For people who have had a heart attack and whose heart is not pumping as well as it should, carvedilol is used to lower the risk of dying from heart-related causes. For high blood pressure, it can be used on its own or combined with other blood pressure medicines.

Most-Reported Side Effects for Carvedilol

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 9,141 reports
Dyspnea 8,542 reports
Diarrhea 7,250 reports
Dizziness 7,211 reports
Nausea 6,830 reports
See full Carvedilol drug information
Keep checking

Other Drugs & Kinetin

Browse every other medication we’ve checked against Kinetin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
122Moderate
0Minor
2,707No known interaction
Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Kinetin page.

No interaction 2,707 drugs checked — show the list
Evidence & sources

Kinetin References

The 7 references that drive our Kinetin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Hsiao, G., Shen, M. Y., Lin, K. H., Chou, C. Y., Tzu, N. H., Lin, C. H., Chou, D. S., Chen, T. F., and Sheu, J. R. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol PubMed
  2. Adunka, O., Moustaklis, E., Weber, A., May, A., von Ilberg, C., Gstoettner, W., and Kierner, A. C. Labyrinth anesthesia--a forgotten but practical treatment option in Meniere's disease. ORL J Otorhinolaryngol.Relat Spec. 2003;65(2):84-90.
  3. Sheu, J. R., Hsiao, G., Shen, M. Y., Chou, C. Y., Lin, C. H., Chen, T. F., and Chou, D. S. Inhibitory mechanisms of kinetin, a plant growth-promoting hormone, in platelet aggregation. Platelets. 2003;14(3):189-196. PubMed
  4. Wanitphakdeedecha R, Meeprathom W, Manuskiatti W. Efficacy and safety of 0.1% kinetin cream in the treatment of photoaging skin. Indian J Dermatol Venereol Leprol. 2015;81(5):547. PubMed
  5. Gold-von Simson G, Goldberg JD, Rolnitzky LM, et al. Kinetin in familial dysautonomia carriers: implications for a new therapeutic strategy targeting mRNA splicing. Pediatr Res. 2009;65(3):341-6. PubMed
  6. Chiu PC, Chan CC, Lin HM, Chiu HC. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. J Cosmet Dermatol. 2007;6(4):243-9. PubMed
  7. Wu JJ, Weinstein GD, Kricorian GJ, Kormeili T, McCullough JL. Topical kinetin 0.1% lotion for improving the signs and symptoms of rosacea. Clin Exp Dermatol. 2007;32(6):693-5. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Kinetin and Carvedilol Together: Common Questions

Is it safe to take Kinetin with Carvedilol?
We do not list a known interaction between Kinetin and Carvedilol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Kinetin and Carvedilol have any of the same side effects?
Yes — our sources link each of them separately to 6 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Kinetin and Carvedilol at the same time of day?
At least one FDA label for a product containing Carvedilol says to take it with food. If you take Kinetin on an empty stomach out of habit, keep them separate and take Carvedilol with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Carvedilol products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Kinetin and Carvedilol combination checked?
Interactions in our licensed database are recorded against drug classes. Carvedilol is filed under 7 classifications, and Kinetin has documented interactions with 1 drug class — none of Carvedilol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Kinetin interact with any other medications?
Yes. Kinetin has 122 documented drug interactions in our database — Carvedilol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Carvedilol interact with any supplements?
Yes. Carvedilol has documented interactions with 211 supplements in our database — Kinetin is not one of them. The Carvedilol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Carvedilol and Kinetin?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.