Drug & supplement interaction

Lemon Verbena + Fentanyl

Fentanyl brand names: Sublimaze, Duragesic, Fentora, Lazanda, Abstral, and others.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Lemon Verbena and Fentanyl in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Lemon Verbena and Fentanyl

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Fentanyl and Lemon Verbena in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lemon Verbena safety at a glance

Lemon Verbena overall Use caution Generally well tolerated as a tea or food, but concentrated extracts and the essential oil are less studied.
Pregnancy Avoid Not enough safety data, so it is best avoided in medicinal amounts during pregnancy.
Breastfeeding Avoid Safety has not been established, so avoid medicinal amounts while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Fentanyl and Lemon Verbena? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Fentanyl

Interactions in our licensed database are recorded against drug classes, not just single drug names. Fentanyl is filed under 10 classifications — including narcotic drugs, serotonergic drugs, serotonergic drugs. Lemon Verbena has documented interactions with 1 drug class — the most serious being benzodiazepines (moderate) — and none of Fentanyl’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lemon Verbena Does Interact With Other Medications

Lemon Verbena has 22 moderate known drug interactions in our database — Fentanyl isn’t one of them. If you take anything else, check it against the full list below.

Moderate 22 No known interaction 2,808 (incl. Fentanyl)
Taking anything else?

Check Another of Your Medications Against Lemon Verbena

Covers the 2,830 medications we’ve checked against Lemon Verbena. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Lemon Verbena and Fentanyl May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Lemon Verbena

    “Contact dermatitis may occur with topical application of lemon verbena (6).”

    Lemon Verbena · Natural Medicines adverse-effect record, reported in dermatitis.

    1 source cited
    1. 6. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

    Fentanyl

    Listed in the ADVERSE REACTIONS section of the FDA label for Fentanyl. Read the label on DailyMed ›

Effects for Fentanyl come from the ADVERSE REACTIONS section of its FDA label; effects for Lemon Verbena come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 114,883 voluntary FDA FAERS reports for Fentanyl that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Lemon Verbena or Fentanyl

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Lemon Verbena or Fentanyl, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Fentanyl

This page covers Lemon Verbena only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Fentanyl page lists 226 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 10 major · 176 moderate · 40 minor.

From our pharmacist’s overview on the Fentanyl page

“There is very little room for error with fentanyl (Duragesic, Sublimaze, Actiq, and other forms), a powerful opioid where a modest rise in blood level or an extra layer of sedation can become dangerous, so this interaction list deserves real respect. Most of the risk falls into two patterns.”

Reviewed by 2 · Jul 18, 2026

Open the Fentanyl interaction page

One more smart check

Taking Lemon Verbena as Part of a Dietary Supplement Product? Check It for Interactions

We hold 32 real supplement products containing Lemon Verbena, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lemon Verbena. Even though Lemon Verbena itself has no known interaction with Fentanyl, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lemon Verbena and Fentanyl Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lemon Verbena
Top half

#681 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Fentanyl
Top 25%

#645 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lemon Verbena reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Lemon Verbena and Fentanyl records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lemon Verbena

What is Lemon Verbena?

Lemon Verbena
  • Digestive upset
  • Anxiety and trouble sleeping
  • Joint pain and inflammation
  • Exercise recovery and oxidative stress
  • Weight management
  • Flavoring and aromatherapy

Lemon verbena is a fragrant South American herb most often enjoyed as a tea or flavoring, and it contains polyphenols like verbascoside that have antioxidant activity in lab studies. Some small studies hint at benefits for inflammation, exercise recovery, and appetite, but the human evidence is limited and far from proven. It is generally well tolerated as a food and tea, but talk with your pharmacist or doctor before using concentrated supplements, and avoid it during pregnancy and breastfeeding.

Aloysia citrodora · Verbenaceae · Leaves and flowering tops; the essential oil is also used · Tea, capsules, liquid extracts, essential oil, and as a flavoring in foods and beverages

An interaction check asks whether these two react with each other — it does not ask whether Lemon Verbena is a good idea for someone in your situation. Here is what our Lemon Verbena record says about it on its own.

Lemon Verbena: dosing

There is no official or well-established standardized dose for lemon verbena. As a tea, it is commonly prepared by steeping the dried leaves in hot water, similar to other herbal teas.For capsules and extracts, products vary widely and some are standardized to a certain percentage of polyphenols or verbascoside. More is not always better, and starting with the lowest amount is a sensible approach.

From our Lemon Verbena monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lemon Verbena monograph & all interactions
Medication

About Fentanyl

What Is Fentanyl Used For?

Brand names: Sublimaze, Duragesic, Fentora, Lazanda, Abstral, Subsys

Fentanyl transdermal system is prescribed for severe, persistent pain that cannot be controlled with other pain medicines, including shorter-acting opioids. It is only for people who are already opioid-tolerant — meaning they've been taking a significant daily opioid dose for at least a week.

It is not for short-term pain, post-surgical pain, mild pain, or use on an as-needed basis. Because of serious risks including addiction, overdose, and death, it is reserved for situations where other treatment options have failed or are not appropriate.

Most-Reported Side Effects for Fentanyl

From FAERS, the FDA’s public side-effect reporting system (114,883 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Drug abuse 12,447 reports
Overdose 8,162 reports
Toxicity to various agents 7,374 reports
Drug dependence 6,445 reports
Nausea 5,689 reports
See full Fentanyl drug information
Keep checking

Other Drugs & Lemon Verbena

Browse every other medication we’ve checked against Lemon Verbena — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
22Moderate
0Minor
2,807No known interaction
22 Moderate 2,807 No interaction
Moderate

22 interactions

No interaction 2,807 drugs checked — show the list

We also checked Lemon Verbena against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,807 medications checked with no known interaction — see the full Lemon Verbena list.

See the full Lemon Verbena interactions page
See every supplement checked against Fentanyl, ranked by severity
Evidence & sources

Lemon Verbena References

The 2 references that drive our Lemon Verbena monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Afrasiabian F, Mirabzadeh Ardakani M, Rahmani K, et al. Aloysia citriodora Palau (lemon verbena) for insomnia patients: A randomized, double-blind, placebo-controlled clinical trial of efficacy and safety. Phytother Res. 2019;33(2):350-359.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lemon Verbena and Fentanyl Together: Common Questions

Is it safe to take Lemon Verbena with Fentanyl?
We do not list a known interaction between Lemon Verbena and Fentanyl. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Lemon Verbena and Fentanyl have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Lemon Verbena and Fentanyl combination checked?
Interactions in our licensed database are recorded against drug classes. Fentanyl is filed under 10 classifications, and Lemon Verbena has documented interactions with 1 drug class — none of Fentanyl's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lemon Verbena interact with any other medications?
Yes. Lemon Verbena has 22 documented drug interactions in our database — Fentanyl is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Fentanyl interact with any supplements?
Yes. Fentanyl has documented interactions with 226 supplements in our database — Lemon Verbena is not one of them. The Fentanyl interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Lemon Verbena monograph Uses, safety profile, and every drug interaction in one place Fentanyl drug information The full plain-English guide to this medication Fentanyl supplement interactions Every supplement checked against Fentanyl, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Fentanyl and Lemon Verbena?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.