Nutmeg - Adempas (Riociguat) Interaction
Herbal: Nutmeg
Also Known As: Myristica fragrans, Buah Pala, Jaatipatree, Jaiphal, Jatiphal, Jatiphala, Jatiphalam, Magic, Muscade, Muscadier, Muskatbaum, Muskatnuss, Myristica, Myristica Oil, Noix de Muscade, Nuez Moscada, Nutmeg
Drug: Riociguat
Brand names:
Adempas
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jun 22, 2025
Interaction Details
There were no interactions found between Riociguat and Nutmeg. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Nutmeg Overview
Nutmeg is a spice that is made from the seed of the nutmeg tree (Myristica fragrans), which is native to Indonesia. The seed is often used as a spice.
Nutmeg has a long history of use in traditional medicine, and is purported to have a number of health benefits. It has been used as a natural remedy for digestive issues, including constipation, diarrhea, and bloating. It is also thought to have anti-inflammatory properties and may be helpful in reducing inflammation and swelling in the body.
It is important to note that large doses of nutmeg can be toxic, and it should be used sparingly.
Riociguat Overview
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Riociguat is used to treat pulmonary arterial hypertension (PAH; high blood pressure in the vessels that carry blood to the lungs). Riociguat is also used to treat chronic thromboembolic pulmonary hypertension (CTEPH; high blood pressure in the lung arteries caused by blood clots that narrow or block blood flow) in adults who cannot have surgery or for those treated with surgery who continue to have high lung blood pressure levels after surgery. Riociguat may improve the ability to exercise in people with PAH and CTEPH and may slow the worsening of symptoms in people with PAH. Riociguat is in a class of medications called soluble guanylate cyclase (sGC) stimulators. It works by relaxing the blood vessels in the lungs to allow blood to flow easily.
Nutmeg - More Interactions
Nutmeg interacts with 523 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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