Drug & supplement interaction

Omega-6 Fatty Acids + Furosemide

Furosemide brand name: Lasix.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Omega-6 Fatty Acids and Furosemide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Omega-6 Fatty Acids and Furosemide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Furosemide and Omega-6 Fatty Acids in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Omega-6 Fatty Acids at all — not against Furosemide, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Omega-6 Fatty Acids safety at a glance

Omega-6 Fatty Acid... overall Use caution Generally safe from food, but supplement benefits are uncertain and balance with omega-3 matters.
Pregnancy Likely Safe When consumed as part of the diet in amounts between 5% and 10% of daily calories according to the Dietary Reference Intake (DRI) Acceptable Macronutrient Distr... Read the full pregnancy detail
Breastfeeding Likely Safe When consumed as part of the diet in amounts between 5% and 10% of daily calories according to the Dietary Reference Intake (DRI) Acceptable Macronutrient Distr... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Furosemide and Omega-6 Fatty Acids? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Omega-6 Fatty Acids Itself Has Been Linked To

This is not an interaction — nothing below involves Furosemide. It is the side-effect record for Omega-6 Fatty Acids on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Omega-6 Fatty Acids, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Bone thinning Worth acting on Additional detail

    “In epidemiological research, increased intake of omega-6 fatty acids was associated with elevated risk of fracture in the elderly.”

    Omega-6 Fatty Acids · Natural Medicines adverse-effect record, reported in fractures.

    1 source cited
    1. 66662. Martinez-Ramirez, M. J., Palma, S., Martinez-Gonzalez, M. A., Delgado-Martinez, A. D., de la Fuente, C., and Delgado-Rodriguez, M. Dietary fat intake and the risk of osteoporotic fractures in the elderly. Eur.J Clin Nutr 2007;61(9):1114-1120. PubMed
  • Raised blood pressure Worth acting on Additional detail

    “Dietary intake of the omega-6 fatty acid linoleic acid in amounts of 5% to 10% of daily calories is appropriate according to the Dietary Reference Intake (DRI) Acceptable Macronutrient Distribution Range (AMDR). However, higher intake levels, especially when compared with omega-3 fatty acid intake, might be detrimental.”

    Omega-6 Fatty Acids · Natural Medicines adverse-effect record, reported in atherosclerosis.

    6 sources cited
    1. 23723. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate. Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/books/03 DOI
    2. 66678. Simopoulos, A. P. The omega-6/omega-3 fatty acid ratio, genetic variation, and cardiovascular disease. Asia Pac.J Clin Nutr 2008;17 Suppl 1:131-134.
    3. 66692. Harris, W. S., Mozaffarian, D., Rimm, E., Kris-Etherton, P., Rudel, L. L., Appel, L. J., Engler, M. M., Engler, M. B., and Sacks, F. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition DOI
    4. 65498. Yamada, T., Strong, J. P., Ishii, T., Ueno, T., Koyama, M., Wagayama, H., Shimizu, A., Sakai, T., Malcom, G. T., and Guzman, M. A. Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan. Atheroscler
    5. 66640. Assies, J., Lok, A., Bockting, C. L., Weverling, G. J., Lieverse, R., Visser, I., Abeling, N. G., Duran, M., and Schene, A. H. Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. Prostaglandins Leukot.Es PubMed
    6. 66642. Chiplonkar, S. A., Agte, V. V., Tarwadi, K. V., Paknikar, K. M., and Diwate, U. P. Micronutrient deficiencies as predisposing factors for hypertension in lacto-vegetarian Indian adults. J Am Coll.Nutr 2004;23(3):239-247. PubMed
  • Trouble sleeping Additional detail

    “In epidemiological research, an increased dietary ratio of omega-6 fatty acids to omega-3 fatty acids has been associated with an elevated risk of having a sleep disorder.”

    Omega-6 Fatty Acids · Natural Medicines adverse-effect record, reported in insomnia.

    1 source cited
    1. 107001. Luo J, Ge H, Sun J, Hao K, Yao W, Zhang D. Associations of dietary ?-3, ?-6 fatty acids consumption with sleep disorders and sleep duration among adults. Nutrients 2021;13(5):1475. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Omega-6 Fatty Acids — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Furosemide’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Furosemide column appears here.

Special populations

Omega-6 Fatty Acids in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When consumed as part of the diet in amounts between 5% and 10% of daily calories according to the Dietary Reference Intake (DRI) Acceptable Macronutrient Distribution Range (AMDR).

Pregnancy And Lactation Possibly Unsafe

When high amounts of omega-6 fatty acids are consumed in the diet. Population research suggests that the highest maternal intakes of omega-6 fatty acids (15.2-47.6 grams or 137-428 kcal daily) during pregnancy is associated with a 2.4-times greater odds of giving birth to an infant below the 10th percentile for birth weight when compared with the lowest maternal intakes (0.4-5.7 grams daily). In addition, population research in women with a history of atopy suggests that the highest blood levels of omega-6 fatty acids during the second trimester is associated with an increased odds of having a child develop atopic dermatitis by age 4-6 years when compared with the lowest intakes. There is insufficient reliable information available about supplemental omega-6 fatty acids; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Omega-6 Fatty Acids or Furosemide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Omega-6 Fatty Acids or Furosemide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Furosemide

This page covers Omega-6 Fatty Acids only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Furosemide page lists 227 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Lithium (major).

By severity: 9 major · 193 moderate · 25 minor.

From our pharmacist’s overview on the Furosemide page

“Yellow dock is where I would start with furosemide (Lasix). This water pill already flushes potassium, and heavy yellow dock use can compound that loss, one of nine major-rated interactions on a list of 227 that deserves genuine care.”

Reviewed by 2 · Jul 18, 2026

Open the Furosemide interaction page

One more smart check

Taking Omega-6 Fatty Acids as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Omega-6 Fatty Acids, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Omega-6 Fatty Acids. Even though Omega-6 Fatty Acids itself has no known interaction with Furosemide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Omega-6 Fatty Acids and Furosemide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Omega-6 Fatty Acids
Steady interest

#1,430 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Furosemide
Top 25%

#567 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Omega-6 Fatty Acids reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Omega-6 Fatty Acids and Furosemide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Omega-6 Fatty Acids

What is Omega-6 Fatty Acids?

  • General nutrition and energy
  • Skin conditions like eczema
  • Inflammation support
  • Heart and cholesterol health
  • Nerve health (such as diabetic nerve discomfort)

Omega-6 fatty acids are essential fats your body needs but cannot make on its own, and most people get plenty from everyday foods like vegetable oils, nuts, and seeds. Supplements such as evening primrose or borage oil are sometimes used for skin or other concerns, but the evidence for added benefit is mixed, and balancing omega-6 with omega-3 fats matters more than taking more omega-6. Talk with your pharmacist or doctor before adding a supplement.

Dietary fats from plant oils, seeds, nuts, and some animal sources · Vegetable oils (corn, soybean, sunflower, safflower), capsules, evening primrose oil, borage oil, and softgels

An interaction check asks whether these two react with each other — it does not ask whether Omega-6 Fatty Acids is a good idea for someone in your situation. Here is what our Omega-6 Fatty Acids record says about it on its own.

Omega-6 Fatty Acids: dosing

There is no single standardized dose of omega-6 fatty acids that works for everyone, and most people meet their needs through diet alone. Health organizations describe omega-6 as an essential nutrient but focus on overall fat balance rather than a specific supplement amount.For supplements like evening primrose oil or borage oil, the right amount depends on the specific product and the GLA content.

From our Omega-6 Fatty Acids monograph — the full record covers uses, side effects and every documented interaction.

Read the full Omega-6 Fatty Acids monograph & all interactions
Medication

About Furosemide

What Is Furosemide Used For?

Brand name: Lasix

Furosemide tablets and oral solution are used in adults and children to treat edema (fluid buildup) caused by congestive heart failure, cirrhosis of the liver, and kidney disease, including nephrotic syndrome. In adults, oral furosemide is also used to treat high blood pressure, alone or alongside other blood pressure medications.

Furosemide injection is reserved for patients who cannot take oral medicine or for emergency situations such as acute pulmonary edema (sudden dangerous fluid in the lungs). Furoscix (subcutaneous injection) is specifically indicated for edema in adults with chronic heart failure or chronic kidney disease, including nephrotic syndrome, and in pediatric patients weighing at least 43 kg. Lasix Onyu (subcutaneous injection) is indicated for edema in adults with chronic heart failure only.

See full Furosemide drug information
Keep checking

Other Drugs & Omega-6 Fatty Acids

Browse every other medication we’ve checked against Omega-6 Fatty Acids — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Omega-6 Fatty Acids against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Omega-6 Fatty Acids list.

See the full Omega-6 Fatty Acids interactions page
See every supplement checked against Furosemide, ranked by severity
Evidence & sources

Omega-6 Fatty Acids References

The 20 references that drive our Omega-6 Fatty Acids monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Godley PA. Essential fatty acid consumption and risk of breast cancer. Breast Cancer Res Treat 1995;35:91-5. PubMed
  2. Newcomer LM, King IB, Wicklund KG, Stanford JL. The association of fatty acids with prostate cancer risk. Prostate 2001;47:262-8. DOI
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate. Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/books/03 DOI
  4. Colter, A. L., Cutler, C., and Meckling, K. A. Fatty acid status and behavioural symptoms of attention deficit hyperactivity disorder in adolescents: a case-control study. Nutr J 2008;7:8. PubMed
  5. Yamada, T., Strong, J. P., Ishii, T., Ueno, T., Koyama, M., Wagayama, H., Shimizu, A., Sakai, T., Malcom, G. T., and Guzman, M. A. Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan. Atheroscler
  6. Conklin, S. M., Manuck, S. B., Yao, J. K., Flory, J. D., Hibbeln, J. R., and Muldoon, M. F. High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism. Psychosom.Med. 2007;69(9):932-934.
  7. Richardson, A. J., Cyhlarova, E., and Ross, M. A. Omega-3 and omega-6 fatty acid concentrations in red blood cell membranes relate to schizotypal traits in healthy adults. Prostaglandins Leukot.Essent.Fatty Acids 2003;69(6):461-466. PubMed
  8. Assies, J., Lok, A., Bockting, C. L., Weverling, G. J., Lieverse, R., Visser, I., Abeling, N. G., Duran, M., and Schene, A. H. Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. Prostaglandins Leukot.Es PubMed
  9. Chiplonkar, S. A., Agte, V. V., Tarwadi, K. V., Paknikar, K. M., and Diwate, U. P. Micronutrient deficiencies as predisposing factors for hypertension in lacto-vegetarian Indian adults. J Am Coll.Nutr 2004;23(3):239-247. PubMed
  10. Mamalakis, G., Kiriakakis, M., Tsibinos, G., Hatzis, C., Flouri, S., Mantzoros, C., and Kafatos, A. Depression and serum adiponectin and adipose omega-3 and omega-6 fatty acids in adolescents. Pharmacol.Biochem.Behav. 2006;85(2):474-479. PubMed
  11. Okuyama, H., Ichikawa, Y., Sun, Y., Hamazaki, T., and Lands, W. E. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. World Rev Nutr Diet. 2007;96:143-1
  12. Martinez-Ramirez, M. J., Palma, S., Martinez-Gonzalez, M. A., Delgado-Martinez, A. D., de la Fuente, C., and Delgado-Rodriguez, M. Dietary fat intake and the risk of osteoporotic fractures in the elderly. Eur.J Clin Nutr 2007;61(9):1114-1120. PubMed
  13. Sonestedt, E., Gullberg, B., and Wirfalt, E. Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer. Public Health Nutr 2007;10(8):769-779. PubMed
  14. Simopoulos, A. P. The omega-6/omega-3 fatty acid ratio, genetic variation, and cardiovascular disease. Asia Pac.J Clin Nutr 2008;17 Suppl 1:131-134.
  15. Harris, W. S., Mozaffarian, D., Rimm, E., Kris-Etherton, P., Rudel, L. L., Appel, L. J., Engler, M. M., Engler, M. B., and Sacks, F. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Omega-6 Fatty Acids and Furosemide Together: Common Questions

Is it safe to take Omega-6 Fatty Acids with Furosemide?
We do not list a known interaction between Omega-6 Fatty Acids and Furosemide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Furosemide interact with any supplements?
Yes. Furosemide has documented interactions with 227 supplements in our database — Omega-6 Fatty Acids is not one of them. The Furosemide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Omega-6 Fatty Acids monograph Uses, safety profile, and every drug interaction in one place Furosemide drug information The full plain-English guide to this medication Furosemide supplement interactions Every supplement checked against Furosemide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 20 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Furosemide and Omega-6 Fatty Acids?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.