Drug & supplement interaction

Quince + Eplerenone

Eplerenone brand name: Inspra.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Quince and Eplerenone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Quince and Eplerenone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Eplerenone and Quince in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Quince at all — not against Eplerenone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Quince safety at a glance

Quince overall Use caution Quince as a food is generally well tolerated, but concentrated supplements are not well studied.
Pregnancy Use caution Quince as food is likely fine, but concentrated extracts or seed products lack safety data, so use caution.
Breastfeeding Use caution There is not enough reliable information on quince supplements during breastfeeding, so caution is advised.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Eplerenone and Quince? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Eplerenone’s Own FDA Label Lists

This is not an interaction — none of it involves Quince. These are the most notable effects listed in the ADVERSE REACTIONS section of Eplerenone’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 8 of them are worth acting on rather than waiting out — marked below.

  • Heart failure Worth acting on mentioned in 7.6% of FDA reports for Eplerenone
  • High potassium Worth acting on
  • Low potassium Worth acting on
  • A heart attack Worth acting on
  • Kidney problems Worth acting on mentioned in 7.4% of FDA reports for Eplerenone
  • Chest pain Worth acting on
  • Raised blood pressure Worth acting on
  • Bleeding or bruising Worth acting on
  • Breast tenderness
  • Dizziness mentioned in 5.3% of FDA reports for Eplerenone

Showing the 10 most notable of 13 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Eplerenone. Read the label on DailyMed › Where a percentage is shown, it is the share of 12,732 voluntary FDA FAERS reports for Eplerenone that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Quince’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Quince side to compare — that is a limit of the record, not a statement that Quince has no side effects.

From our Q&A

Questions About Quince or Eplerenone

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Quince or Eplerenone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Eplerenone

This page covers Quince only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Eplerenone page lists 136 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Tyramine (major) and Adrafinil (moderate).

By severity: 4 major · 111 moderate · 21 minor.

Open the Eplerenone interaction page

One more smart check

Taking Quince as Part of a Dietary Supplement Product? Check It for Interactions

We hold 25 real supplement products containing Quince, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Quince. Even though Quince itself has no known interaction with Eplerenone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Quince and Eplerenone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Quince
Steady interest

#930 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Eplerenone
Top 25%

#561 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Quince and Eplerenone records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Quince

What is Quince?

  • Digestive upset and diarrhea
  • Acid reflux and heartburn
  • Sore throat and cough
  • Skin soothing and wound care
  • Nausea

Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.

Cydonia oblonga · Rosaceae · Fruit, seeds, and leaves · Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts

An interaction check asks whether these two react with each other — it does not ask whether Quince is a good idea for someone in your situation. Here is what our Quince record says about it on its own.

Quince: dosing

There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds.

From our Quince monograph — the full record covers uses, side effects and every documented interaction.

Read the full Quince monograph & all interactions
Medication

About Eplerenone

What Is Eplerenone Used For?

Brand name: Inspra

Eplerenone treats two conditions. First, it is used to lower high blood pressure (hypertension) in adults. Lowering blood pressure reduces the risk of stroke and heart attack. It can be used alone or alongside other blood pressure medicines.

Second, eplerenone is used to improve survival in stable adults who have heart failure with reduced ejection fraction (HFrEF) — meaning the heart pumps less blood than normal — following an acute myocardial infarction (heart attack).

Most-Reported Side Effects for Eplerenone

From FAERS, the FDA’s public side-effect reporting system (12,732 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 1,138 reports
Cardiac failure 966 reports
Acute kidney injury 946 reports
Hypotension 888 reports
Fatigue 690 reports
See full Eplerenone drug information
Keep checking

Other Drugs & Quince

Browse every other medication we’ve checked against Quince — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Quince against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Quince list.

See the full Quince interactions page
See every supplement checked against Eplerenone, ranked by severity
Sources

Sources & How We Checked

We checked Quince against Eplerenone in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Quince monograph › Uses, safety, and every drug interaction in one place Eplerenone supplement interactions › Every supplement checked against Eplerenone, ranked by severity Eplerenone drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Quince and Eplerenone Together: Common Questions

Is it safe to take Quince with Eplerenone?
We do not list a known interaction between Quince and Eplerenone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Eplerenone interact with any supplements?
Yes. Eplerenone has documented interactions with 136 supplements in our database — Quince is not one of them. The Eplerenone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Eplerenone and Quince?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.