Drug & supplement interaction

Strophanthus + Docetaxel

Docetaxel brand name: Taxotere.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Strophanthus and Docetaxel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Strophanthus and Docetaxel

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Docetaxel and Strophanthus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Strophanthus safety at a glance

Strophanthus overall Avoid Strophanthus contains potent, potentially toxic cardiac glycosides and should only be used under direct medical supervision.
Pregnancy Unsafe When used orally due to possible uterine stimulating effects; avoid using. Read the full pregnancy detail
Breastfeeding Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Docetaxel and Strophanthus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Docetaxel

Interactions in our licensed database are recorded against drug classes, not just single drug names. Docetaxel is filed under 2 classifications — including cytochrome p450 3a4 (cyp3a4) substrates. Strophanthus has documented interactions with 6 drug classes — the most serious being quinidine (major), quinine (major) and corticosteroids (moderate) — and none of Docetaxel’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Strophanthus Does Interact With Other Medications

Strophanthus has 3 major, 120 moderate known drug interactions in our database — Docetaxel isn’t one of them. If you take anything else, check it against the full list below.

Major 3 Moderate 120 No known interaction 2,707 (incl. Docetaxel)
Taking anything else?

Check Another of Your Medications Against Strophanthus

Covers the 2,830 medications we’ve checked against Strophanthus. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Strophanthus and Docetaxel May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Vomiting / Nausea Additional detail

    Strophanthus

    “Orally, side effects include nausea, vomiting, headache, stupor, disturbance of color vision, and cardiac arrhythmias, particularly during overdose (18).”

    Strophanthus · Natural Medicines adverse-effect record, reported in arrhythmia.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, side effects include nausea and vomiting (18).”

    Strophanthus · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Docetaxel

    Listed in the ADVERSE REACTIONS section of the FDA label for Docetaxel. Read the label on DailyMed ›

Reported for Strophanthus but not commonly for Docetaxel: an irregular heartbeat and headache.

Effects for Docetaxel come from the ADVERSE REACTIONS section of its FDA label; effects for Strophanthus come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Strophanthus in Pregnancy & Breastfeeding

Pregnancy Unsafe

When used orally due to possible uterine stimulating effects; avoid using.

Lactation Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Docetaxel

This page covers Strophanthus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Docetaxel page lists 121 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 87 moderate · 32 minor.

From our pharmacist’s overview on the Docetaxel page

“Grapefruit is the first thing I would take off the menu during docetaxel (Taxotere) chemotherapy. It blocks CYP3A4, the liver enzyme that clears docetaxel, and higher levels of a chemotherapy drug mean harsher side effects, not better results.”

Reviewed by 2 · Jul 18, 2026

Open the Docetaxel interaction page

How much people look this up

Where Strophanthus and Docetaxel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Strophanthus
Steady interest

#988 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Docetaxel
Top half

#795 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Strophanthus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Strophanthus and Docetaxel records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Strophanthus

What is Strophanthus?

  • Heart failure
  • Angina (chest pain)
  • Irregular heartbeat
  • Circulation support
  • Traditional African arrow poison (historical)

Strophanthus is a plant that contains powerful heart-affecting compounds called cardiac glycosides (the best known is ouabain/g-strophanthin). Because these substances can strongly affect heart rhythm and are toxic in the wrong amount, Strophanthus is not a casual supplement and should never be used without close medical supervision. Reliable modern evidence for its supplement use is limited.

Strophanthus gratus · Apocynaceae · Seeds (and the seed-derived glycoside ouabain/g-strophanthin) · Oral drops/tinctures, capsules, and historically injectable extracts (mostly outside the U.S.)

An interaction check asks whether these two react with each other — it does not ask whether Strophanthus is a good idea for someone in your situation. Here is what our Strophanthus record says about it on its own.

Strophanthus: dosing

There is no well-established, standardized supplement dose for Strophanthus, and the strength of products can vary a lot. Because the active glycosides are potent and potentially toxic, picking a dose on your own is not safe.If a product is used, follow the exact directions on the label and use it only under the supervision of a qualified healthcare provider. We deliberately do not list specific milligram amounts here.

From our Strophanthus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Strophanthus monograph & all interactions
Medication

About Docetaxel Injection

What Is Docetaxel Injection Used For?

Brand name: Taxotere

Docetaxel Injection is used to treat a number of serious cancers. Beizray (docetaxel injection) is approved as a single agent for locally advanced or metastatic breast cancer after prior chemotherapy has stopped working, and in combination with doxorubicin and cyclophosphamide as adjuvant (after-surgery) treatment for operable node-positive breast cancer. It is also used as a single agent for locally advanced or metastatic non-small cell lung cancer (NSCLC) after platinum-based chemotherapy has failed, and with cisplatin for chemotherapy-naive advanced NSCLC.

Beizray is used with prednisone for metastatic castration-resistant prostate cancer. It is also used with cisplatin and fluorouracil for advanced gastric adenocarcinoma (including gastroesophageal junction cancer) in patients who have not received prior chemotherapy for advanced disease, and for induction treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN).

Most-Reported Side Effects for Docetaxel

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Alopecia 16,970 reports
Madarosis 6,717 reports
Hair texture abnormal 5,993 reports
Hair colour changes 5,874 reports
Hair disorder 5,625 reports
See full Docetaxel Injection drug information
Keep checking

Other Drugs & Strophanthus

Browse every other medication we’ve checked against Strophanthus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

3Major
120Moderate
0Minor
2,706No known interaction
3 Major 120 Moderate 2,706 No interaction
Major

3 interactions

Moderate

120 interactions

Showing 60 of 120 moderate interactions — see all 120 on the Strophanthus page.

No interaction 2,706 drugs checked — show the list

We also checked Strophanthus against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,706 medications checked with no known interaction — see the full Strophanthus list.

See the full Strophanthus interactions page
See every supplement checked against Docetaxel, ranked by severity
Evidence & sources

Strophanthus References

The 4 references that drive our Strophanthus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Tyler VE, Brady LR, Robbers JE. Pharmacognosy. 9th ed. Philadelphia, PA: Lea & Febiger, 1988.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Strophanthus and Docetaxel Together: Common Questions

Is it safe to take Strophanthus with Docetaxel?
We do not list a known interaction between Strophanthus and Docetaxel. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Strophanthus and Docetaxel have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Strophanthus and Docetaxel combination checked?
Interactions in our licensed database are recorded against drug classes. Docetaxel is filed under 2 classifications, and Strophanthus has documented interactions with 6 drug classes — none of Docetaxel's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Strophanthus interact with any other medications?
Yes. Strophanthus has 123 documented drug interactions in our database — Docetaxel is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Docetaxel interact with any supplements?
Yes. Docetaxel has documented interactions with 121 supplements in our database — Strophanthus is not one of them. The Docetaxel interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Strophanthus monograph Uses, safety profile, and every drug interaction in one place Docetaxel Injection drug information The full plain-English guide to this medication Docetaxel supplement interactions Every supplement checked against Docetaxel, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Docetaxel and Strophanthus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.