Drug & supplement interaction

Thymus Extract + Temozolomide

Temozolomide brand name: Temodar.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Thymus Extract and Temozolomide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Temozolomide states a food rule worth keeping to.

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Interaction report

Thymus Extract and Temozolomide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Temozolomide and Thymus Extract in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Thymus Extract safety at a glance

Thymus Extract overall Use caution Human safety data are limited, and animal-tissue products carry a small risk of contamination.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety during breastfeeding is unknown, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Temozolomide and Thymus Extract? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Temozolomide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Temozolomide is filed under 3 classifications — alkylating agents, antineoplastics, oral drugs. Thymus Extract has documented interactions with 1 drug class — the most serious being immunosuppressants (moderate) — and none of Temozolomide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Thymus Extract Does Interact With Other Medications

Thymus Extract has 121 moderate known drug interactions in our database — Temozolomide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 121 No known interaction 2,709 (incl. Temozolomide)
Taking anything else?

Check Another of Your Medications Against Thymus Extract

Covers the 2,830 medications we’ve checked against Thymus Extract. Pick one to open its full report.

What to actually watch for

What Temozolomide’s Own FDA Label Lists

This is not an interaction — none of it involves Thymus Extract. These are the most notable effects listed in the ADVERSE REACTIONS section of Temozolomide’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on
  • A low platelet count Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • A higher chance of infection Worth acting on
  • Dry skin
  • Hair loss
  • Reduced appetite
  • Constipation
  • Tiredness

Showing the 10 most notable of 14 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Temozolomide. Read the label on DailyMed › Thymus Extract’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Thymus Extract side to compare — that is a limit of the record, not a statement that Thymus Extract has no side effects.

How to take them

Some Temozolomide Products Have a Food Rule — Thymus Extract Should Not Break It

At least one FDA label for a product containing Temozolomide says to take it on an empty stomach. Most supplements — Thymus Extract included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Temozolomide on its own and move Thymus Extract to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Temozolomide products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

To reduce nausea and vomiting, take TEMODAR on an empty stomach or at bedtime and consider antiemetic therapy prior to and following TEMODAR administration.

From the Dosage and Administration section of the FDA label we read for Temozolomide — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Overlapping uses

What Temozolomide Is Prescribed For, and What Thymus Extract Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Temozolomide is a prescription medicine with approved uses on its FDA label. Thymus Extract is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Temozolomide is prescribed for: Temozolomide treats two types of aggressive brain tumors in adults: glioblastoma and anaplastic astrocytoma. For newly diagnosed glioblastoma, it is given alongside radiation therapy and then continued as maintenance treatment. For anaplastic astrocytoma, Temodar (the brand-name injection/capsule product) is approved for adjuvant treatment of newly diagnosed cases as well as refractory cases (tumors that have stopped responding to other treatment). Temozolomide Capsules, USP are approved for newly diagnosed glioblastoma and for refractory anaplastic astrocytoma in patients whose disease progressed on a regimen containing nitrosourea and procarbazine.

Thymus Extract has been studied for:

  • Cancer studied, not established Thymus Extract has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Thymus Extract for cancer

    Although there has been interest in using oral thymus extract for cancer, there is insufficient reliable information about the clinical effects of thymus extract for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Temozolomide on your own; if you are taking Thymus Extract for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Thymus Extract or Temozolomide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Thymus Extract or Temozolomide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Temozolomide

This page covers Thymus Extract only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Temozolomide page lists 25 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Acerola (moderate), Alpha-lipoic Acid (moderate), Coenzyme Q10 (moderate) and Coffee Charcoal (moderate).

By severity: 1 major · 14 moderate · 10 minor.

From our pharmacist’s overview on the Temozolomide page

“Temozolomide (Temodar) is an oral chemotherapy pill, usually prescribed for aggressive brain tumors, and stakes that high make me treat this list with real caution. Most of the 25 supplements on file interfere in the gut, where fibers, gums, and charcoals may bind the drug or change how much of it gets absorbed.”

Reviewed by 2 · Jul 18, 2026

Open the Temozolomide interaction page

How much people look this up

Where Thymus Extract and Temozolomide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Thymus Extract
Steady interest

#740 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Temozolomide
Steady interest

#2,470 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Thymus Extract reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Thymus Extract and Temozolomide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Thymus Extract

What is Thymus Extract?

  • Immune system support
  • Frequent infections
  • Allergies
  • Autoimmune conditions
  • Cancer supportive care

Thymus extract is a glandular product made from the thymus tissue of animals, and it is promoted mainly for immune support. The evidence is mostly limited, preliminary, or from older studies, so it should not replace proven treatments. Because it is an animal-tissue product, talk with your pharmacist or doctor before using it, especially if you have a serious medical condition.

Thymus gland tissue, usually from cattle or sheep · Capsules, tablets, oral liquid, injectable preparations (in some countries)

An interaction check asks whether these two react with each other — it does not ask whether Thymus Extract is a good idea for someone in your situation. Here is what our Thymus Extract record says about it on its own.

Thymus Extract: dosing

There is no well-established standard dose for thymus extract, and products vary widely in their strength and source. Do not assume that taking more is safer or more effective.

From our Thymus Extract monograph — the full record covers uses, side effects and every documented interaction.

Read the full Thymus Extract monograph & all interactions
Medication

About Temozolomide

What Is Temozolomide Used For?

Brand name: Temodar

Temozolomide treats two types of aggressive brain tumors in adults: glioblastoma and anaplastic astrocytoma. For newly diagnosed glioblastoma, it is given alongside radiation therapy and then continued as maintenance treatment.

For anaplastic astrocytoma, Temodar (the brand-name injection/capsule product) is approved for adjuvant treatment of newly diagnosed cases as well as refractory cases (tumors that have stopped responding to other treatment). Temozolomide Capsules, USP are approved for newly diagnosed glioblastoma and for refractory anaplastic astrocytoma in patients whose disease progressed on a regimen containing nitrosourea and procarbazine.

Most-Reported Side Effects for Temozolomide

From FAERS, the FDA’s public side-effect reporting system (20,946 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Disease progression 1,887 reports
Thrombocytopenia 1,569 reports
Nausea 1,310 reports
Fatigue 1,037 reports
Neutropenia 1,035 reports
See full Temozolomide drug information
Keep checking

Other Drugs & Thymus Extract

Browse every other medication we’ve checked against Thymus Extract — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
121Moderate
0Minor
2,708No known interaction
121 Moderate 2,708 No interaction
Moderate

121 interactions

Showing 60 of 121 moderate interactions — see all 121 on the Thymus Extract page.

No interaction 2,708 drugs checked — show the list

We also checked Thymus Extract against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,708 medications checked with no known interaction — see the full Thymus Extract list.

See the full Thymus Extract interactions page
See every supplement checked against Temozolomide, ranked by severity
Evidence & sources

Thymus Extract References

The 2 references that drive our Thymus Extract monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Nationwide alert on hallmark labs injectable adrenal cortex extract. FDA. Available at: www.fda.gov/bbs/topics/NEWS/NEW00539.html

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Thymus Extract and Temozolomide Together: Common Questions

Is it safe to take Thymus Extract with Temozolomide?
We do not list a known interaction between Thymus Extract and Temozolomide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Thymus Extract and Temozolomide at the same time of day?
At least one FDA label for a product containing Temozolomide says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Temozolomide on its own and move Thymus Extract to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Are Thymus Extract and Temozolomide used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Thymus Extract in each. That is a conversation for your prescriber, especially if Temozolomide is being adjusted to a target.
How was the Thymus Extract and Temozolomide combination checked?
Interactions in our licensed database are recorded against drug classes. Temozolomide is filed under 3 classifications, and Thymus Extract has documented interactions with 1 drug class — none of Temozolomide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Thymus Extract interact with any other medications?
Yes. Thymus Extract has 121 documented drug interactions in our database — Temozolomide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Temozolomide interact with any supplements?
Yes. Temozolomide has documented interactions with 25 supplements in our database — Thymus Extract is not one of them. The Temozolomide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Thymus Extract monograph Uses, safety profile, and every drug interaction in one place Temozolomide drug information The full plain-English guide to this medication Temozolomide supplement interactions Every supplement checked against Temozolomide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Temozolomide and Thymus Extract?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.