Drug & supplement interaction

Zedoary + Mipomersen Sodium

Mipomersen Sodium brand name: Kynamro.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Zedoary and Mipomersen Sodium in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Zedoary and Mipomersen Sodium

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mipomersen Sodium and Zedoary in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Zedoary safety at a glance

Zedoary overall Use caution Generally used in food amounts, but human safety data for supplement doses is limited.
Pregnancy Likely Unsafe When used orally. Zedoary is thought to have abortifacient effects; avoid using. Read the full pregnancy detail
Breastfeeding Avoid No reliable safety information during breastfeeding, so it is best avoided.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mipomersen Sodium and Zedoary? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mipomersen Sodium

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mipomersen Sodium is filed under a single classification — hepatotoxic drugs. Zedoary has documented interactions with 1 drug class — the most serious being cytochrome p450 3a4 (cyp3a4) substrates (moderate) — and none of Mipomersen Sodium’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Zedoary Does Interact With Other Medications

Zedoary has 643 moderate known drug interactions in our database — Mipomersen Sodium isn’t one of them. If you take anything else, check it against the full list below.

Moderate 643 No known interaction 2,187 (incl. Mipomersen Sodium)
Taking anything else?

Check Another of Your Medications Against Zedoary

Covers the 2,830 medications we’ve checked against Zedoary. Pick one to open its full report.

Special populations

Zedoary in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally. Zedoary is thought to have abortifacient effects; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Mipomersen Sodium Is Prescribed For, and What Zedoary Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Mipomersen Sodium is a prescription medicine with approved uses on its FDA label. Zedoary is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Zedoary has been studied for:

  • Hypercholesterolemia studied, not established Zedoary has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Zedoary for hypercholesterolemia

    Taking 200 mL of tea prepared with 0.5 gram, 1 gram, or 1.5 grams of zedoary root powder twice daily between meals for 2 months reduces total cholesterol by 9%, 14% and 17% respectively in non-obese men aged 25-40 years with mild hypercholesterolemia. The highest dose also seems to increase high-density lipoprotein (HDL) cholesterol by 6.8%.

    1 source cited
    1. 99637. Tariq S, Imran M, Mushtaq Z, Asghar N. Phytopreventive antihypercholesterolemic and antilipidemic perspectives of zedoary (Curcuma Zedoaria Roscoe) herbal tea. Lipids Health Dis 2016;15:39. doi: 10.1186/s12944-016-0210-y.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Mipomersen Sodium on your own; if you are taking Zedoary for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Mipomersen Sodium

This page covers Zedoary only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mipomersen Sodium page lists 38 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).

By severity: 3 major · 35 moderate.

From our pharmacist’s overview on the Mipomersen Sodium page

“Kynamro (mipomersen sodium) treats a severe inherited cholesterol disorder, and it already carries a serious warning about liver injury on its own. All 38 supplements and herbs on this page interact the same way, by adding their own liver stress to a medicine that is hard on that organ to begin with, so approach this list with genuine…”

Reviewed by 2 · Jul 18, 2026

Open the Mipomersen Sodium interaction page

One more smart check

Taking Zedoary as Part of a Dietary Supplement Product? Check It for Interactions

We hold 83 real supplement products containing Zedoary, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Zedoary. Even though Zedoary itself has no known interaction with Mipomersen Sodium, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Zedoary and Mipomersen Sodium Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Zedoary
Steady interest

#1,065 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mipomersen Sodium
Steady interest

#1,860 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Zedoary reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Zedoary and Mipomersen Sodium records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Zedoary

What is Zedoary?

  • Digestive upset and bloating
  • Loss of appetite
  • Menstrual discomfort
  • Inflammation and pain
  • Traditional flavoring and tonic

Zedoary is a ginger-family root used in traditional Asian and Indian medicine, mostly for digestion and as a spice. Scientific evidence in humans is very limited, so its benefits are not well proven. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy.

Curcuma zedoaria · Zingiberaceae · Rhizome (root) and essential oil · Dried powder, capsules, tinctures, essential oil, tea

An interaction check asks whether these two react with each other — it does not ask whether Zedoary is a good idea for someone in your situation. Here is what our Zedoary record says about it on its own.

Zedoary: dosing

There is no standardized, well-established dose for zedoary. The right amount depends on the form (powder, capsule, tincture, or oil) and the product's strength.The safest approach is to follow the directions on the product label and not exceed them.

From our Zedoary monograph — the full record covers uses, side effects and every documented interaction.

Read the full Zedoary monograph & all interactions
Medication

About Mipomersen Injection

What Is Mipomersen Injection Used For?

Brand name: Kynamro

  • Mipomersen injection is used to decrease levels of cholesterol and other fatty substances in the blood in people who have homozygous familial hypercholesterolemia (HoFH; a rare inherited condition that causes very high levels of cholesterol in the blood, increasing the risk of serious heart disease). Some people with HoFH may be treated with LDL apheresis (a procedure that removes LDL from the blood), but mipomersen injection should not be used along with this treatment. Mipomersen injection should not be used to decrease cholesterol levels in people who do not have HoFH. Mipomersen injection is in a class of medications called antisense oligonucleotide (ASO) inhibitors. It works by preventing certain fatty substances from forming in the body.

See full Mipomersen Injection drug information
Keep checking

Other Drugs & Zedoary

Browse every other medication we’ve checked against Zedoary — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
643Moderate
0Minor
2,186No known interaction
643 Moderate 2,186 No interaction
Moderate

643 interactions

Showing 60 of 643 moderate interactions — see all 643 on the Zedoary page.

No interaction 2,186 drugs checked — show the list

We also checked Zedoary against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,186 medications checked with no known interaction — see the full Zedoary list.

See the full Zedoary interactions page
See every supplement checked against Mipomersen Sodium, ranked by severity
Evidence & sources

Zedoary References

The 5 references that drive our Zedoary monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Tariq S, Imran M, Mushtaq Z, Asghar N. Phytopreventive antihypercholesterolemic and antilipidemic perspectives of zedoary (Curcuma Zedoaria Roscoe) herbal tea. Lipids Health Dis 2016;15:39. doi: 10.1186/s12944-016-0210-y.
  4. Rodseeda C, Yamanont P, Pinthong D, Korprasertthaworn P. Inhibitory effects of Thai herbal extracts on the cytochrome P450 3A-mediated the metabolism of gefitinib, lapatinib and sorafenib. Toxicol Rep 2022;9:1846-1852. PubMed
  5. Niu LQ, Xiao L, Cai QH, et al. Comparative effectiveness of Chinese herbal injections treating for rotavirus enteritis in children: A systematic review and Bayesian network meta-analysis. Integr Med Res 2023;12(2):100944. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Zedoary and Mipomersen Sodium Together: Common Questions

Is it safe to take Zedoary with Mipomersen Sodium?
We do not list a known interaction between Zedoary and Mipomersen Sodium. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Zedoary and Mipomersen Sodium used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Zedoary in each. That is a conversation for your prescriber, especially if Mipomersen Sodium is being adjusted to a target.
How was the Zedoary and Mipomersen Sodium combination checked?
Interactions in our licensed database are recorded against drug classes. Mipomersen Sodium is filed under 1 classification, and Zedoary has documented interactions with 1 drug class — none of Mipomersen Sodium's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Zedoary interact with any other medications?
Yes. Zedoary has 643 documented drug interactions in our database — Mipomersen Sodium is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mipomersen Sodium interact with any supplements?
Yes. Mipomersen Sodium has documented interactions with 38 supplements in our database — Zedoary is not one of them. The Mipomersen Sodium interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Zedoary monograph Uses, safety profile, and every drug interaction in one place Mipomersen Injection drug information The full plain-English guide to this medication Mipomersen Sodium supplement interactions Every supplement checked against Mipomersen Sodium, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mipomersen Sodium and Zedoary?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.