Drug & supplement interaction

Zedoary + Panitumumab

Panitumumab brand name: Vectibix.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Zedoary and Panitumumab in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Zedoary and Panitumumab

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Panitumumab and Zedoary in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Zedoary safety at a glance

Zedoary overall Use caution Generally used in food amounts, but human safety data for supplement doses is limited.
Pregnancy Likely Unsafe When used orally. Zedoary is thought to have abortifacient effects; avoid using. Read the full pregnancy detail
Breastfeeding Avoid No reliable safety information during breastfeeding, so it is best avoided.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Panitumumab and Zedoary? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Panitumumab

Interactions in our licensed database are recorded against drug classes, not just single drug names. Panitumumab is filed under a single classification — antineoplastics. Zedoary has documented interactions with 1 drug class — the most serious being cytochrome p450 3a4 (cyp3a4) substrates (moderate) — and none of Panitumumab’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Zedoary Does Interact With Other Medications

Zedoary has 643 moderate known drug interactions in our database — Panitumumab isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Zedoary

Covers the 2,830 medications we’ve checked against Zedoary. Pick one to open its full report.

What to actually watch for

What Panitumumab’s Own FDA Label Lists

This is not an interaction — none of it involves Zedoary. These are the most notable effects listed in the ADVERSE REACTIONS section of Panitumumab’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • An electrolyte imbalance Worth acting on
  • Low magnesium Worth acting on
  • A bowel blockage Worth acting on
  • Dehydration Worth acting on
  • Low potassium Worth acting on
  • Blood clots Worth acting on
  • Wheezing Worth acting on
  • A severe skin reaction Worth acting on
  • Chest pain Worth acting on
  • Kidney problems Worth acting on

Showing the 10 most notable of 43 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Panitumumab. Read the label on DailyMed › Zedoary’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Zedoary side to compare — that is a limit of the record, not a statement that Zedoary has no side effects.

Special populations

Zedoary in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally. Zedoary is thought to have abortifacient effects; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Panitumumab

This page covers Zedoary only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Panitumumab page lists 1 supplement it has a documented interaction with, worst first, each one explained.

The most serious there right now: American Pawpaw (minor).

By severity: 1 minor.

From our pharmacist’s overview on the Panitumumab page

“Panitumumab (Vectibix) is an infused antibody used against certain colorectal cancers, and its supplement interaction file is about as short as they come. A single ingredient appears on it, American pawpaw, and even that is rated minor, with the evidence suggesting the interaction is unlikely to occur at all.”

Reviewed by 2 · Jul 18, 2026

Open the Panitumumab interaction page

One more smart check

Taking Zedoary as Part of a Dietary Supplement Product? Check It for Interactions

We hold 83 real supplement products containing Zedoary, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Zedoary. Even though Zedoary itself has no known interaction with Panitumumab, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Zedoary and Panitumumab Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Zedoary
Top half

#723 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Panitumumab
Steady interest

#2,518 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Zedoary reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Zedoary and Panitumumab records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Zedoary

What is Zedoary?

  • Digestive upset and bloating
  • Loss of appetite
  • Menstrual discomfort
  • Inflammation and pain
  • Traditional flavoring and tonic

Zedoary is a ginger-family root used in traditional Asian and Indian medicine, mostly for digestion and as a spice. Scientific evidence in humans is very limited, so its benefits are not well proven. Talk with your pharmacist or doctor before using it, and avoid it during pregnancy.

Curcuma zedoaria · Zingiberaceae · Rhizome (root) and essential oil · Dried powder, capsules, tinctures, essential oil, tea

An interaction check asks whether these two react with each other — it does not ask whether Zedoary is a good idea for someone in your situation. Here is what our Zedoary record says about it on its own.

Zedoary: dosing

There is no standardized, well-established dose for zedoary. The right amount depends on the form (powder, capsule, tincture, or oil) and the product's strength.The safest approach is to follow the directions on the product label and not exceed them.

From our Zedoary monograph — the full record covers uses, side effects and every documented interaction.

Read the full Zedoary monograph & all interactions
Medication

About Panitumumab Injection

What Is Panitumumab Injection Used For?

Brand name: Vectibix

Vectibix (panitumumab injection) is used to treat metastatic colorectal cancer (mCRC) in adults. It is approved for patients whose tumors have a specific genetic profile — either wild-type RAS (no RAS mutations in KRAS or NRAS) or a KRAS G12C mutation — as confirmed by an FDA-approved test before starting treatment.

For wild-type RAS mCRC, Vectibix may be used alone after prior chemotherapy has stopped working, or in combination with FOLFOX chemotherapy as a first-line treatment. For KRAS G12C-mutated mCRC, Vectibix is used in combination with sotorasib in patients who have already received fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy. Vectibix is not appropriate for patients with RAS-mutant mCRC (except in the specific KRAS G12C combination setting) or for patients whose RAS mutation status is unknown.

See full Panitumumab Injection drug information
Keep checking

Other Drugs & Zedoary

Browse every other medication we’ve checked against Zedoary — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
643Moderate
0Minor
2,186No known interaction
Moderate

643 interactions

Showing 60 of 643 moderate interactions — see all 643 on the Zedoary page.

No interaction 2,186 drugs checked — show the list
Evidence & sources

Zedoary References

The 5 references that drive our Zedoary monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Tariq S, Imran M, Mushtaq Z, Asghar N. Phytopreventive antihypercholesterolemic and antilipidemic perspectives of zedoary (Curcuma Zedoaria Roscoe) herbal tea. Lipids Health Dis 2016;15:39. doi: 10.1186/s12944-016-0210-y.
  4. Rodseeda C, Yamanont P, Pinthong D, Korprasertthaworn P. Inhibitory effects of Thai herbal extracts on the cytochrome P450 3A-mediated the metabolism of gefitinib, lapatinib and sorafenib. Toxicol Rep 2022;9:1846-1852. PubMed
  5. Niu LQ, Xiao L, Cai QH, et al. Comparative effectiveness of Chinese herbal injections treating for rotavirus enteritis in children: A systematic review and Bayesian network meta-analysis. Integr Med Res 2023;12(2):100944. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Zedoary and Panitumumab Together: Common Questions

Is it safe to take Zedoary with Panitumumab?
We do not list a known interaction between Zedoary and Panitumumab. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Zedoary and Panitumumab combination checked?
Interactions in our licensed database are recorded against drug classes. Panitumumab is filed under 1 classification, and Zedoary has documented interactions with 1 drug class — none of Panitumumab's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Zedoary interact with any other medications?
Yes. Zedoary has 643 documented drug interactions in our database — Panitumumab is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Panitumumab interact with any supplements?
Yes. Panitumumab has documented interactions with 1 supplement in our database — Zedoary is not one of them. The Panitumumab interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Panitumumab and Zedoary?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.