Medication interaction hub

What Supplements Interact with Daunorubicin, Cytarabine?

Daunorubicin, Cytarabine brand name: Vyxeos. Every interaction below applies to the brands too.

50 Interactions 3 Major 47 Moderate
Curated & coded by · Clinical Pharmacist · Updated September 18, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Daunorubicin, Cytarabine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Daunorubicin, Cytarabine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Vyxeos pairs daunorubicin and cytarabine to treat acute myeloid leukemia, and its supplement list is one to handle with genuine care. Most of it points at the liver: 38 of the 50 flagged ingredients can stress an organ already processing intensive chemotherapy, and the three rated major all belong to that group. Two of those three are simply beer and wine, because alcohol on top of this treatment raises the chance of liver injury, and the third is Siberian cocklebur, an herb tied on its own to liver failure.

The remaining entries fall into two smaller patterns. A handful of antioxidant supplements might theoretically dull the cancer-killing action of the daunorubicin component, and a few herbs may make seizures more likely. Nothing here rates minor, which fits how seriously I would take it; each item deserves a conversation with your oncology team. Across the full list, 47 entries are moderate alongside those 3 majors.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 47 No known interaction 1,402

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Daunorubicin, Cytarabine: Top Interactions at a Glance

The Daunorubicin, Cytarabine supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 50 interacting ingredients — plus 1,402 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Daunorubicin, Cytarabine Combinations Today

The Daunorubicin, Cytarabine + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Greater Celandine + Daunorubicin, Cytarabinei

There is some concern that greater celandine can adversely affect the liver.

Read the full interaction Moderate Likelihood Possible Acerola + Daunorubicin, Cytarabinei

Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.

Read the full interaction Moderate Likelihood Possible Buchu + Daunorubicin, Cytarabinei

Buchu contains pulegone, a known hepatotoxin.

Read the full interaction Moderate Likelihood Possible Saigon Cinnamon + Daunorubicin, Cytarabinei

Theoretically, Saigon cinnamon might cause additive effects when used with hepatotoxic drugs.

Read the full interaction Major Likelihood Likely Siberian Cocklebur + Daunorubicin, Cytarabinei

Siberian cocklebur can adversely affect the liver.

Read the full interaction Major Likelihood Probable Beer + Daunorubicin, Cytarabinei

Concomitant use of alcohol with hepatotoxic drugs may increase the risk of hepatotoxicity.

Read the full interaction
The complete list

Every Supplement Checked Against Daunorubicin, Cytarabine

All 1,452 ingredients in our database, ranked by severity — 50 with a Daunorubicin, Cytarabine interaction on file and 1,402 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Daunorubicin, Cytarabine?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Greater Celandine with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that greater celandine can adversely affect the liver.

Full Greater Celandine + Daunorubicin, Cytarabine answer

Can you take Acerola with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.

Full Acerola + Daunorubicin, Cytarabine answer

Can you take Buchu with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Buchu contains pulegone, a known hepatotoxin.

Full Buchu + Daunorubicin, Cytarabine answer

Can you take Saigon Cinnamon with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Saigon cinnamon might cause additive effects when used with hepatotoxic drugs.

Full Saigon Cinnamon + Daunorubicin, Cytarabine answer

Can you take Hemp Agrimony with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hemp agrimony contains hepatotoxic pyrrolizidine alkaloids (PA).

Full Hemp Agrimony + Daunorubicin, Cytarabine answer

Can you take Kava with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, using kava with hepatotoxic drugs might increase the risk of liver damage.

Full Kava + Daunorubicin, Cytarabine answer

Can you take Khella with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, khella might have additive adverse effects on the liver when used with hepatotoxic drugs.

Full Khella + Daunorubicin, Cytarabine answer

Can you take Kudzu with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive hepatotoxic effects.

Full Kudzu + Daunorubicin, Cytarabine answer

Can you take Ligandrol with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive hepatotoxic effects.

Full Ligandrol + Daunorubicin, Cytarabine answer

Can you take Manchurian Thorn with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that high doses of Manchurian thorn can induce liver damage.

Full Manchurian Thorn + Daunorubicin, Cytarabine answer

Can you take Melatonin with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking melatonin with drugs that lower the seizure threshold might increase the risk of seizure activity.

Full Melatonin + Daunorubicin, Cytarabine answer

Can you take Niacin with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.

Full Niacin + Daunorubicin, Cytarabine answer

Can you take Noni with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.

Full Noni + Daunorubicin, Cytarabine answer

Can you take Ostarine with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use with hepatotoxic drugs might increase the risk of adverse hepatotoxic effects.

Full Ostarine + Daunorubicin, Cytarabine answer

Can you take Padang Cassia with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that ingesting large amounts of Padang cassia might cause hepatotoxicity in some people.

Full Padang Cassia + Daunorubicin, Cytarabine answer

Can you take Rauwolscine with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.

Full Rauwolscine + Daunorubicin, Cytarabine answer

Can you take Red Yeast Rice with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk of liver damage.

Full Red Yeast Rice + Daunorubicin, Cytarabine answer

Can you take Rhubarb with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.

Full Rhubarb + Daunorubicin, Cytarabine answer

Can you take Rose Hip with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, the antioxidant effects of rose hip might reduce the effectiveness of antitumor antibiotics.

Full Rose Hip + Daunorubicin, Cytarabine answer

Can you take Spearmint with Daunorubicin, Cytarabine?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of spearmint might increase the risk of liver damage when taken with hepatotoxic drugs.

Full Spearmint + Daunorubicin, Cytarabine answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Daunorubicin, Cytarabine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Daunorubicin, Cytarabine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Daunorubicin, Cytarabine sits in 4 interaction categories. Open any one to see what the group means:

Hepatotoxic Drugs 38 ingredients

Medications with known liver considerations. Supplements that can stress the liver add to the load.

38 of the supplement ingredients on this page reach Daunorubicin, Cytarabine through this category.

Antitumor Antibiotics 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Daunorubicin, Cytarabine through this category.

Seizure Threshold Lowering Drugs 6 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

6 of the supplement ingredients on this page reach Daunorubicin, Cytarabine through this category.

Topoisomerase Ii Inhibitors 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Daunorubicin, Cytarabine through this category.

About Daunorubicin, Cytarabine

Daunorubicin, Cytarabine is a prescription medication also sold under the brand name Vyxeos. Because supplements and herbal products can change how medications work — or how strongly — every ingredient on this page has been checked against it in our interaction database.

Generic name: Daunorubicin, Cytarabine  ·  Brand name: Vyxeos.

See the full Daunorubicin and Cytarabine Lipid Complex Injection drug information

Related: does Daunorubicin, Cytarabine deplete any nutrients?

Daunorubicin, Cytarabine has 1 reported nutrient association in the research literature — see the Daunorubicin, Cytarabine nutrient depletion report.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Daunorubicin, Cytarabine

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Daunorubicin, Cytarabine.

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Pharmacist Counseling Corner

Daunorubicin, Cytarabine & Supplements: Common Questions

What supplements interact with Daunorubicin, Cytarabine?
In our interaction database, 50 supplement and herbal ingredients have an interaction with Daunorubicin, Cytarabine on file — 3 rated major, 47 moderate, and 0 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Siberian Cocklebur, Beer, Wine.
Which Daunorubicin, Cytarabine supplement interactions are the most serious?
The 3 major-rated combinations — led by Siberian Cocklebur, Beer and Wine — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Daunorubicin, Cytarabine?
That depends entirely on which supplement. The honest answer for Daunorubicin, Cytarabine is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Vyxeos have the same supplement interactions as Daunorubicin, Cytarabine?
Yes — Vyxeos all contain Daunorubicin, Cytarabine, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
Does Daunorubicin, Cytarabine deplete any vitamins or nutrients?
It might — Daunorubicin, Cytarabine has 1 reported nutrient-depletion association in the research literature, which is a different question from interactions: instead of a supplement changing the drug, the drug may lower a nutrient over time. See the Daunorubicin, Cytarabine nutrient depletion report for the specifics and what to discuss with your pharmacist.
What about Daunorubicin, Cytarabine and my other medications?
This page covers Daunorubicin, Cytarabine against supplements and herbal ingredients. Checking Daunorubicin, Cytarabine against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Daunorubicin and Cytarabine Lipid Complex Injection drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 18, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.