Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Acidophilus With Pectin Ingredients & Drug Interactions

by Country Life

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Acidophilus With Pectin is a dietary supplement by Country Life with 4 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 188 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus, Citrus Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Acidophilus With Pectin by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (240 mg) without saying how much of each component you get.

This capsule contains 4 active ingredients. Lactobacillus acidophilus is a live probiotic bacterium — a "good" microorganism meant to support gut health.

Citrus Pectin is a soluble fiber extracted from citrus fruit. The product also includes a Proprietary Probiotic Blend and complex Marine Polysaccharides.

In addition, there are several inactive ingredients — Cellulose, Magnesium Stearate, Stearic Acid, and Silica — which serve as capsule material and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“support digestive health”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Hypercholesterolemia — rated "Possibly Effective" (Pectin) (Natural Medicines).
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Lactobacillus Acidophilus) (Natural Medicines).

The evidence for Lactobacillus acidophilus shows it's possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis. It's rated possibly ineffective for atopic disease (allergic conditions), and there isn't enough reliable evidence to rate it for acute respiratory distress syndrome.

Citrus Pectin is possibly effective for high cholesterol (hypercholesterolemia). The evidence for its use in prediabetes and radiation exposure is insufficient to draw conclusions.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Pectin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Gastrointestinal side effects — such as stomach discomfort, bloating, gas, diarrhea, and burping — can occur when taken with other probiotics, but these are uncommon.

Because L. acidophilus contains live organisms, there's a theoretical concern it could cause infection in some patients, though this is rare and usually occurs in people with weakened immunity or serious underlying illness. In pregnancy, L. acidophilus is rated possibly safe, but there's limited data on breastfeeding safety — talk with your doctor or pharmacist.

Citrus Pectin from food sources and typical supplement amounts is generally well tolerated. The most common side effects are mild: diarrhea, gas, loose stools, and cramping.

Allergic reactions, including severe ones like anaphylaxis, are rare but possible in people sensitive to pectin. In pregnancy and lactation, pectin from food is likely safe, but concentrated supplement safety during pregnancy and breastfeeding hasn't been well studied — check with your doctor before use.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Pectin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Pectin, Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 188 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check if you're on digoxin (Lanoxin) or any tetracycline antibiotic — Citrus Pectin may reduce how much of these drugs you absorb, making them less effective. Lovastatin (Mevacor) for cholesterol also interacts the same way.

Additionally, any antibiotic drug might reduce how well the Lactobacillus acidophilus works; your pharmacist can suggest timing to separate them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with certain digestive and bowel conditions if you're not on antibiotics or certain heart or cholesterol medications. If you take digoxin, lovastatin, tetracycline antibiotics, or any other prescription medication, check your exact drugs with the tool on this page before starting.

Talk to your pharmacist about the best timing if you're on antibiotics.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Acidophilus With Pectin, straight from the product label.

Brand Country Life
Barcode (UPC) 015794030522
Net contents 250 Vegan Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 326777
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Acidophilus With Pectin by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
125
UPC/BARCODE
015794030522
IngredientAmount% DV
Maltodextrin0 NP--
Proprietary Probiotic Blend240 mg--
Lactobacillus acidophilus0 NP--
complex Marine Polysaccharides0 NP--
Citrus Pectin200 mg--

Other ingredients: Cellulose, Magnesium Stearate, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Acidophilus is a probiotic strain used to support digestive health and Country Life's established Acidophilus formula provides 2.4 billion CFUs per serving (at the time of manufacture). (Viable cell count at the time of manufacture.) This probiotic helps to support microflora balance. Country Life's Acidophilus formula is protected by the unique MAKTrek delivery system.

2.4 billion CFUs per serving (at the time of manufacture)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Yes Certified Gluten-Free by GFCO.org No Yeast, wheat or soy No Milk, salt or preservatives No Artificial colors, flavors or sweeteners No GMOs

Yes Certified Vegan by the AVA

Yes Manufacturing supports wind power

This product has been manufactured at a GMP Registered facility.

GF Certified Gluten-Free Dairy-Free Certified Gluten-Free

Supports digestive health Helps to support microflora balance

General Statements

Yes Recyclable Packaging

Our Pledge of Integrity Authenticity Cleanliness Freshness Consistency Accuracy

Brand IP Statement(s)

MAKTrek is a trademark of MAK Wood, Inc.

Established 1971 Country Life

Seals/Symbols

Certified B Corporation GF Certified Gluten-Free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take two (2) capsules once daily with food.

Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers. Caution: If you are pregnant, nursing, or taking medication, have a medical condition or planning surgery, consult a doctor before using this product.

Stop using and consult a doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store in a dry place between 59 degrees - 86 degrees F. Best if refrigerated.

See for yourself

Acidophilus With Pectin by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Acidophilus With Pectin by Country Life

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container125 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

240 mg per serving

Citrus Pectin

Interacts with
23 drugs
200 mg per serving Form: Citrus spp.

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...

Citrus Pectin monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Acidophilus With Pectin by Country Life Drug Interactions

Want to check YOUR meds against Acidophilus With Pectin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
188Drugs
188 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Acidophilus With Pectin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D

Citrus Pectin3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Acidophilus With Pectin, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Acidophilus With Pectin by Country Life: Common Questions

Does Acidophilus With Pectin by Country Life interact with any medications?
Yes. Based on its ingredients, Acidophilus With Pectin has a known interaction with 188 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Acidophilus With Pectin contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on an antibiotic?
Antibiotics can kill the live organisms in this probiotic, so it won't work as well. It's usually best to take them at different times — ask your pharmacist how many hours apart. If you're on a tetracycline antibiotic like doxycycline, that's also an ingredient interaction to watch for with the pectin in this product.
Is this safe during pregnancy?
Lactobacillus acidophilus is rated possibly safe in pregnancy, and citrus pectin from food is likely safe. However, data on concentrated pectin supplements during pregnancy are limited. Talk with your doctor before starting to make sure it's right for you.
What are the most common side effects?
The live probiotic and pectin may cause mild gastrointestinal symptoms — bloating, gas, diarrhea, or stomach cramping — but these are uncommon. If you're sensitive to pectin, allergic reactions are rare but possible.
Will this help my IBS?
Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, meaning there's evidence it may help, but it's not proven for everyone. Talk with your doctor about whether it makes sense for your specific situation.
Does this product help lower cholesterol?
Citrus Pectin is possibly effective for high cholesterol. However, if you're on lovastatin (Mevacor), this product may interfere with how much of that drug your body absorbs — so check with your pharmacist first.
Can I take this while breastfeeding?
Lactobacillus acidophilus data on breastfeeding safety is limited, and the same goes for concentrated pectin supplements. Dietary amounts of pectin are likely fine, but ask your doctor before taking this supplement while nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Acidophilus With Pectin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Acidophilus With Pectin label
Sources

Sources & How We Checked

Acidophilus With Pectin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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